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VIDD Staff Scientists & Physicians

Parul Agrawal, Ph.D

Parul Agrawal, Ph.D

Staff Scientist, Stamatatos Lab, Vaccine and Infectious Disease Division, Fred Hutch

Pre-clinical evaluation of vaccine candidates and adjuvants in animal models. Specifically, monitor the activation, survival and maturation of B cells that produce protective antibodies against HIV-1. Designing and characterizing HIV-1 immunogens.

Erica Andersen-Nissen, Ph.D.

Erica Andersen-Nissen, Ph.D.

Senior Staff Scientist, McElrath Lab, Vaccine and Infectious Disease Division, Fred Hutch
Laboratory Director, Cape Town HVTN Immunology Laboratory

Research interests include early innate immune responses to HIV vaccines on subsequent adaptive immune responses and systems biology analyses of how immune responses are shaped.

Michele Andrasik, Ph.D.

Michele Andrasik, Ph.D.

Director, Social & Behavioral Sciences and Community Engagement, HIV Vaccine Trials Network (HVTN) & COVID-19 Prevention Network (CoVPN)
Senior Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Affiliate Assistant Professor, Global Health, University of Washington
Affiliate Assistant Professor, Environmental and Occupational Health Sciences, University of Washington

Research interests include sexual risk taking, victimization and alcohol/drug abuse among African-American women, HIV prevention for African American and African-born populations and health disparities.

Jessica Andriesen, Ph.D.

Jessica Andriesen, Ph.D.

Senior Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Clinical trial data management, Logistics, operations and study facilitation, Scientific communications, Host-pathogen interactions High-dimensional data analysis.

Rena D. Astronomo, Ph.D.

Rena D. Astronomo, Ph.D.

Staff Scientist, McElrath Lab, Vaccine and Infectious Disease Division, Fred Hutch

Research interests include understanding mucosal immune responses to viral infections and vaccines, in particular, the contribution of passively administered and vaccine elicited antibodies to protection against HIV-1 transmission at the cervicovaginal mucosa.

Martine Aubert, Ph.D.

Martine Aubert, Ph.D.

Senior Staff Scientist, Jerome Lab, Vaccine and Infectious Disease Division, Fred Hutch

Research interests include targeting latent viral genomes for mutagenesis and disruption of viral pathogenesis and infection using engineered homing endonucleases.

Erwing Fabian Cardozo-Ojeda, M.S., Ph.D.

Erwing Fabian Cardozo-Ojeda, M.S., Ph.D.

Staff Scientist, Schiffer Group, Vaccine and Infectious Disease Division, Fred Hutch

Mathematical modeling of virus and immune system dynamics. Population/within-host dynamics approach to quantify HIV-1 infection and treatment efficacy (ordinary differential equations, nonlinear mixed effects models).

Kristen Cohen, Ph.D.

Kristen Cohen, Ph.D.

Senior Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Characterization of immunological “signature” associated with development of cross-neutralizing antibody responses in HIV-infected individuals.

Leonard D'Amico, Ph.D.

Leonard D'Amico, Ph.D.

Staff Scientist, Cancer Immunotherapy Trials Network (CITN), Vaccine and Infectious Disease Division, Fred Hutch

Immune profiling of cancer immunotherapy clinical trial subjects to further the understanding of therapy-driven patient immune responses in order to develop more effective cancer treatments.

Sayan Dasgupta, Ph.D.

Sayan Dasgupta, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Staff Scientist, Biostatistics, Bioinformatics & Epidemiology

Interests include supervised learning methods in infectious disease modeling, semiparametrics and Bayesian assessment of complex models.

Allan C. deCamp, Ph.D.

Allan C. deCamp, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Correlates analysis, sieve analysis and antigenic mapping focusing on HIV-1 vaccines and immunology.

Dobromir Dimitrov, Ph.D.

Dobromir Dimitrov, Ph.D.

Senior Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Senior Staff Scientist, Public Health Sciences Division, Fred Hutch
Affiliate Assistant Professor, Applied Mathematics, University of Washington

Research interests include mathematical modeling of infectious diseases, evaluating impact of interventions for HIV prevention, mathematical biology (population dynamics, epidemic modeling) and dynamical systems (ODE, PDE, and impulsive systems).

One Bridget Dintwe, Ph.D.

One Bridget Dintwe, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Research Officer, Cape Town HVTN Immunology Laboratory

Oversight for quality control of Good Clinical Lab Practice (GCLP)-compliant assays and is studying cellular immune responses to HIV vaccines for the Cape Town HVTN laboratory. Research involves interrogation of the phenotype and transcriptional profile of vaccine induced T cells in order to better understand these T cell responses.

Clara P. Domínguez Islas, Ph.D.

Clara P. Domínguez Islas, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Design and analysis of trials for HIV prevention, methods for meta-analysis of clinical trials, Bayesian approaches for extrapolation of efficacy between populations.

Tracy Qi Dong, Ph.D.

Tracy Qi Dong, Ph.D.

Staff Scientist, Biostatistics, Bioinformatics and Epidemiology Program, Vaccine and Infectious Disease Division, Fred Hutch

Research interests include statistical models of infectious diseases, analysis of observational and interventional studies, space-time modeling, and survey statistics.

Mike Duff, Ph.D.

Mike Duff, Ph.D.

Staff Scientist, Biostatistics, Bioinformatics and Epidemiology Program, Vaccine and Infectious Disease Division, Fred Hutch

B cell receptor sequence analysis

Paul Edlefsen, Ph.D.

Paul Edlefsen, Ph.D.

Senior Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Affiliate Assistant Professor, Biostatistics, University of Washington

Statistical and computational methods for bioinformatics applications, statistical modeling for genome sequence analysis and statistical modeling frameworks. The interface between computer science, statistics, and molecular biology and such as development of new informatics methods in genomics and post-genomics.

Karsten Eichholz, Ph.D.

Karsten Eichholz, Ph.D.

Staff Scientist, Corey Lab, Vaccine and Infectious Disease Division, Fred Hutch

Research interests include development of cellular immunotherapies for HIV, chimeric antigen receptor design and in vitro testing, in vitro and in situ imaging of chimeric antigen receptor T cells.

Lynda Marie Emel, Ph.D.

Lynda Marie Emel, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Associate Director, HPTN Statistical and Data Management Center, Vaccine and Infectious Disease Division, Fred Hutch

Clinical trial design and operations, good clinical data management practices (GCDMP), research regulations, behavioral research methodology, research ethics.

Andrew Fiore-Gartland, Ph.D.

Andrew Fiore-Gartland, Ph.D.

Senior Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Current studies include development of methods for T-cell based sieve analysis, quantification of vaccine induced T cell responses, systems biology of influenza and time-dependent correlates analysis of HIV efficacy trial.

Leigh Fisher, Ph.D.

Leigh Fisher, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

HVTN cross-protocol analyses

Steve Fling, Ph.D.

Steve Fling, Ph.D.

Senior Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Immune monitoring and correlative science analyses for early clinical trials in the area of cancer immunotherapy.

Briana D. Furch, M.D., MPH

Briana D. Furch, M.D., MPH

Staff Physician, Vaccine and Infectious Disease Division, Fred Hutch
Clinical Trials Physician/Protocol Team Lead, HIV Vaccine Trials Network (HVTN) & CoVID 19 Prevention Network (CoVPN) Core

Research area includes immunology and vaccine design for development of vaccines, especially HIV-1 and SARS-CoV-2.

Elena E. Giorgi, Ph.D.

Elena E. Giorgi, Ph.D.

Senior Staff Scientist, Biostatistics, Bioinformatics and Epidemiology Program, Vaccine and Infectious Disease Division, Fred Hutch

Research area includes developing mathematical and statistical models to study viral evolution, immune correlates in infectious diseases (HIV, HCV, and SARS-CoV-2 in particular), and vaccine design. 

Jessica Graham, Ph.D.

Jessica Graham, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Roles of regulatory T cells in modulating anti-viral immunity, understanding the host immune response in anti-viral immunity and vaccine development.

Matthew D. Gray, Ph.D.

Matthew D. Gray, Ph.D.

Senior Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Construction and evaluation of recombinant viral vectors for B cell engineering studies in mouse, human, and non-human primates. Molecular analyses of B cell responses to vaccination and tumor antigens. Binding and structural studies on neutralizing antibodies and their pathogen targets. Development of mono-, bi-, and tri-specific single-chain antibodies for B cell engineering studies and therapeutics. Optimization of Fc effector functions and circulation half-life for improved antibody therapeutics.

Nicole Grunenberg, M.D.

Nicole Grunenberg, M.D.

Staff Physician, Vaccine and Infectious Disease Division, Fred Hutch
Clinical Trials Physician/Protocol Team Leader, HIV Vaccine Trials Network (HVTN)

Immunology and vaccine design for development of vaccines, especially HIV-1 vaccine.

Brett Hanscom, Ph.D.

Brett Hanscom, Ph.D.

Senior Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Design and analytic methods for HIV prevention trials and measurement-error modeling and bias correction.

Joe (Jue) Hou, Ph.D.

Joe (Jue) Hou, Ph.D.

Senior Staff Scientist, Corey Lab, Vaccine and Infectious Disease Division, Fred Hutch

Utilizing computational immunology approaches to (1) reveal disease-induced specific immune responses and subsets in the temporal and spatial patterns; (2) explore the mechanism and disparity of vaccine protection; (3) discover the mechanism of individual variances in immune responses.

Tzu-Jung Huang, Ph.D.

Tzu-Jung Huang, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Staff Scientist, Vaccine Immunology Statistical Center

Research interests include high-dimensional testing, post-selection inference, statistical analysis and designs of platform trials, survival analysis, and vaccine efficacy evaluation.

John Huddleston, Ph.D.

John Huddleston, Ph.D.

Staff Scientist, Bedford Lab, Biostatistics, Bioinformatics and Epidemiology Program, Vaccine and Infectious Disease Division, Fred Hutch

Within the Bedford Lab, work includes independent research, software development, and educational outreach and mentorship. Research focus involves the evolution of seasonal influenza viruses, development of computational models to predict the composition of future influenza populations, and contribution of reports to the World Health Organization’s vaccine composition meetings. Also a core developer of Nextstrain’s real-time pathogen surveillance tools including the Augur bioinformatics toolkit and the SARS-CoV-2 genomic epidemiology workflow. This work builds on previous professional roles as a bioinformatics specialist and software developer and previous educational experiences including a master’s degrees in computer science and biology.

John Hural, Ph.D.

John Hural, Ph.D.

Senior Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Associate Director for Laboratory Operations, HIV Vaccine Trials Network (HVTN)

Immunologic endpoint determination for experimental vaccines (HIV, pneumococcus, malaria, TB, flu) and Logistics, operations, quality assurance, and assay validation for immunologic evaluation of vaccines in the clinical trial setting.

Andrew Johnson, Ph.D., B.S.

Andrew Johnson, Ph.D., B.S.

Staff Scientist, Kublin Lab, Vaccine and Infectious Disease Division, Fred Hutch

Research interests include understanding how the microbiome regulates our immune response, especially in the context of vaccination. In particular, studying how microbial exposure shapes immune development and the response to vaccination.

Daniel Jones, Ph.D.

Daniel Jones, Ph.D.

Staff Scientist, Newell Lab, Vaccine and Infectious Disease Division, Fred Hutch

Developing statistical methods for the analysis of spatial transcriptomics and spatial genomics data.

Michal Juraska, Ph.D.

Michal Juraska, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Design and analysis of vaccine efficacy trials, genotype-specific vaccine efficacy-based sieve analysis, immune correlates of vaccine protection, analysis of vaccine-induced immune response durability and survival analysis.

Latha Kallur Siddaramaiah, Ph.D.

Latha Kallur Siddaramaiah, Ph.D.

Staff Scientist, Stamatatos Lab, Vaccine and Infectious Disease Division, Fred Hutch

Research interests include vaccine manufacturing, characterization and immunological evaluation of drug substance and drug product, and vaccine adjuvant studies.

Shelly Karuna, M.D., MPH

Shelly Karuna, M.D., MPH

Senior Staff Physician, Vaccine and Infectious Disease Division, Fred Hutch
Director of Clinical Development, HIV Vaccine Trials Network (HVTN)
Clinical Trials Physician/Protocol Team Leader, HIV Vaccine Trials Network (HVTN)

HIV vaccine development and trial design, combination HIV prevention, mucosal immunology and mucosal sampling design in HIV prevention trials, the intersection of oncology and infectious disease, comparative effectiveness, decision analysis and health-related quality of life.

Angela Shaulov Kask, Ph.D.

Angela Shaulov Kask, Ph.D.

Staff Scientist, Cancer Immunotherapy Trials Network (CITN), Vaccine and Infectious Disease Division, Fred Hutch

Research interests include Cancer Immunology/Translational Immunology/Viral Immunology/Cellular Immunology, immune monitoring and correlative science data analyses in cancer immunotherapy clinical trials.

Maria P. Lemos, Ph.D., MPH

Maria P. Lemos, Ph.D., MPH

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Research focus includes studying the barrier and immune mechanisms that contribute to protection after circumcision, vaccine or passive immunizations at mucosal sites of encounter with HIV.

Shuying (Sue) Li, Ph.D.

Shuying (Sue) Li, Ph.D.

Senior Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Senior Staff Scientist, Public Health Sciences Division, Fred Hutch

Development of genetic statistical methodologies, including phylogenetic tree reconstruction from genetic sequences.

Xiaohong Li, Ph.D.

Xiaohong Li, Ph.D.

Staff Scientist, Biostatistics, Bioinformatics and Epidemiology Program, Vaccine and Infectious Disease Division, Fred Hutch

Application of statistical and machine learning methods in molecular genetics and immunology of infectious diseases. Study relationship of human host genetics, SARS-Cov-2 clinical symptoms and immunogenicity reaction. Longitudinal immunogenicity reactions after SARS-Cov-2 infection. SARS-Cov-2 and HIV virus evolutionary dynamics over time and clonal dynamics interactions in human hosts and HIV infected population. Population dynamics of infectious disease transmission and interactions between hosts and pathogen from molecular genetics point of view. Quantitative evaluation of early detection of cancer and infectious diseases.

Troy Martin, M.D., MPH

Troy Martin, M.D., MPH

Staff Scientist, HIV Vaccine Trials Network (HVTN), Vaccine and Infectious Disease Division, Fred Hutch

Research interests include the development of HIV vaccines for adults and children. Part of the core leadership team on network strategic planning and implementation, as the HVTN Chief of Staff. Primary research focus is in the HVTN’s phase 1 experimental medicine program for induction of broadly neutralizing antibodies against sites of vulnerability on the HIV envelope protein.

Laura Matrajt, Ph.D.

Laura Matrajt, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Research lies at the interface of mathematics, computer science, biology, and public health policy. Utilizing and developing quantitative tools including dynamical systems, differential equations, stochastic processes, operations research and optimization to understand complex biological processes.

Bryan T. Mayer, Ph.D.

Bryan T. Mayer, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Staff Scientist, Vaccine Immunology Statistical Center

Research interests include analysis of immune response to vaccine candidates, study design for pilot studies, statistical methods for biological assays, and infectious disease models.

Samuel Minot, Ph.D.

Samuel Minot, Ph.D.

Staff Scientist, Fredricks Lab, Vaccine and Infectious Disease Division, Fred Hutch

Research focus includes the role of the microbiome in human health and disease.

Zoe Moodie, Ph.D.

Zoe Moodie, Ph.D.

Senior Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Senior Staff Scientist, Public Health Sciences Division, Fred Hutch

Research focus includes design and analysis of vaccine clinical trials, immune correlates of risk and protection, statistical training and capacity building.

Mia Moore, Ph.D.

Mia Moore, Ph.D.

Staff Scientist, Biostatistics, Bioinformatics and Epidemiology Program, Vaccine and Infectious Disease Division, Fred Hutch

Mathematical modeling of HIV and CoVID epidemiology

Carmen Paez, M.D., MBA

Carmen Paez, M.D., MBA

Staff Physician, Vaccine and Infectious Disease Division, Fred Hutch
Clinical Trials Physician/Protocol Team Leader, HIV Vaccine Trials Network (HVTN)

HIV vaccine development and clinical trial design. Monoclonal antibodies clinical trial design for HIV prevention. Mucosal sampling in HIV prevention clinical trials. Leadership in developing and implementing clinical trials for HIV vaccines and monoclonal antibodies. Safety monitoring oversight for clinical trials.

Rachael Parks, Ph.D.

Rachael Parks, Ph.D.

Staff Scientist, HIV Vaccine Trials Network (HVTN), Vaccine and Infectious Disease Division, Fred Hutch

Immune profiling of antigen-specific B cell responses to vaccines and infection.

Sivasankaran M. Ponnan, Ph.D.

Sivasankaran M. Ponnan, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Staff Scientist (T-cell Immunologist), HIV Vaccine Trials Network (HVTN)

Oversight of the Good Clinical Lab Practice (GCLP) - compliant assays and studies cellular immune responses to candidate vaccines at the HVTN End Point GCLP laboratory. Execute assays supporting the HVTN and CoVPN clinical trials and assist with clinical trial operations. Research interests include single-cell genomics and high parameter flow cytometry to examine vaccine-induced T cells' proliferative capabilities, phenotypic traits, and migration potential.

Nirasha Ramchurren, Ph.D.

Nirasha Ramchurren, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Identifying correlates of immune response in immunotherapy trials

April Kaur Randhawa, Ph.D.

April Kaur Randhawa, Ph.D.

Senior Staff Scientist, Biostatistics, Bioinformatics and Epidemiology Program, Vaccine and Infectious Disease Division, Fred Hutch
Associate Director, Laboratory & Data Science, HIV Vaccine Trials Network (HVTN) & COVID-19 Prevention Network (CoVPN)

Infectious disease biologist researching prevention strategies for globally important pathogens such as HIV, tuberculosis, and COVID-19.

Daniel B. Reeves, Ph.D.

Daniel B. Reeves, Ph.D.

Staff Scientist, Schiffer Group, Vaccine and Infectious Disease Division, Fred Hutch

Creates mathematical models of viral and immune system dynamics and evolution. Uses theoretical and computational methods to better understand host-pathogen interplay and inform the development of preventative and curative interventions.

Mingchao Shen, Ph.D.

Mingchao Shen, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Associate Director Project Management, HVTN Laboratory Center, HIV Vaccine Trials Network (HVTN)

Research focus includes preclinical animal models for vaccines and adjuvants testing, vaccine product development and clinical trial design, vaccine adjuvants, formulations and innate immune responses, immunological evaluation of vaccines and project management for collaborative research projects.

Anton M. Sholukh, Ph.D.

Anton M. Sholukh, Ph.D.

Senior Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Research focus includes the analysis of humoral immune response to HSV-2 and its vaccine candidates and understanding the role of tissue B cells in HSV-2 infection.

Timothy Skalland, Ph.D.

Timothy Skalland, Ph.D.

Staff Scientist, Biostatistics, Bioinformatics & Epidemiology, Vaccine and Infectious Disease Division, Fred Hutch

Research interests include the design and analysis of group-sequential and complex clinical trials, specifically as pertaining to HIV prevention trials.

Sujatha Srinivasan, Ph.D.

Sujatha Srinivasan, Ph.D.

Senior Staff Scientist, Fredricks Lab, Vaccine and Infectious Disease Division, Fred Hutch

Research focus includes ecology of human microbial communities, impact of bacterial interactions on health and disease, molecular diagnosis of bacterial pathogens and bacterial adaptive responses.

Daniel Stone, Ph.D.

Daniel Stone, Ph.D.

Senior Staff Scientist, Jerome Lab, Vaccine and Infectious Disease Division, Fred Hutch

Research focus includes development of DNA editing enzymes that target the genomes of viruses that undergo latent infections and viral vectors for gene delivery to sites of latent viral infection.

Jean de Dieu Tapsoba, Ph.D.

Jean de Dieu Tapsoba, Ph.D.

Staff Scientist, Biostatistics, Bioinformatics and Epidemiology Program, Vaccine and Infectious Disease Division, Fred Hutch

Research focus includes the development and application of statistical methods to account for measurement error, missing data and selection bias in regression analyses of cross-sectional, longitudinal or survival data from clinical trials and observational studies in cancer and HIV/AIDS prevention research areas.

Manuel V. Villaran, M.D., M.S., MPH

Manuel V. Villaran, M.D., M.S., MPH

Clinical Trials Physician/Protocol Team Leader, HIV Vaccine Trials Network (HVTN), Vaccine and Infectious Disease Division, Fred Hutch

HIV and COVID-19 vaccine development and trial design

Stephaun Elite Wallace, Ph.D., M.S.

Stephaun Elite Wallace, Ph.D., M.S.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch
Director of External Relations, HIV Vaccine Trials Network, Fred Hutch
Clinical Assistant Professor, Dept. of Global Health, University of Washington

Research commitment, inquiry, and interests are situated at the intersection of public health and social justice to further understand and mitigate the impacts of structural and social factors like stigma, racism, sexism, homophobia/transphobia, historical trauma, and education and income inequities on population-level health. Particularly interested in the health and wellbeing of Black and LGBTQ populations.

Marius Walter, Ph.D.

Marius Walter, Ph.D.

Staff Scientist, Jerome Lab, Vaccine and Infectious Disease Division, Fred Hutch

Development of viral vectors to cure latent infections with herpesviruses

Sahar Zangenah, Ph.D.

Sahar Zangenah, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Research is focused on statistical analysis of survey data, Bayesian modeling including Bayesian nonparametrics and the design and analysis of vaccine studies.

Yifan Zhu, Ph.D.

Yifan Zhu, Ph.D.

Staff Scientist, Vaccine and Infectious Disease Division, Fred Hutch

Statistical methods in HIV/AIDS research and monitoring and analyzing drug adherence patterns. Transmission models for infectious disease epidemiology.