Clinical Trials & Studies
Fred Hutch scientists conduct hundreds of clinical trials and volunteer studies, often in collaboration with the University of Washington, Seattle Children’s and Seattle Cancer Care Alliance, our clinical care partner.
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Clinical Trials FAQ
Find answers to frequently asked questions about clinical trials and observational studies, including:
What are clinical trial phases? Are clinical trials safe? How do observational studies differ from clinical trials? Are study participants paid?
Studies Open for Enrollment
Volunteer participation in clinical trials and observational studies is vital to disease research. No matter how promising a new drug, vaccine or procedure looks when tested in the laboratory or on animals, it cannot be approved for general use in humans until it has been carefully evaluated through several phases of clinical study that include volunteer participants. Through our clinical trials, patients gain access to promising new treatments for cancer and other diseases, as well as new vaccines for diseases such as HIV.
Observational studies are also crucial to determining cause and effect in human health, including how behavior, lifestyle, genetic factors and other traits may help prevent disease or contribute to disease risk. Some of our studies seek healthy participants for prevention research that may involve dietary changes, vitamin supplementation, increased physical activity or adoption of other health-promoting behaviors.
Below are studies that are still enrolling participants. Some involve healthy volunteers, and some seek patients with particular diagnoses or medical histories. Each study describes its enrollment criteria in detail, and many offer online screening tools for prospective participants.
Malaria Studies
We are working to develop vaccines and medicines to prevent and limit malaria. To do this, we need healthy volunteers to take part in our clinical research studies. Read the general criteria and use our screening tool to see if you qualify for a study.
PALS Study
Prostate Cancer Active Lifestyle (PALS) is enrolling volunteers with low-grade prostate cancer who have chosen active surveillance of their disease. The goal is to learn whether weight loss through diet and exercise can slow the progression of prostate cancer.
FRESH Study
Some studies have shown that frequent eating is associated with lower risk for certain diseases, while other studies suggest that eating the standard three meals a day is better. We are recruiting healthy adults between the ages of 18 to 50 to participate in a a study that examines how eating patterns influence health and appetite.
ACE Study
The Acute Effects of Exercise on Breast Cancer Biomarkers (ACE Study) is enrolling women to test the effect of moderate intensity exercise on cancer risk factors such as biomarkers in healthy women. Knowing if exercise significantly alters these biomarkers, could help support guidelines for daily exercise for breast cancer prevention and could indicate that exercise even without weight loss is beneficial.
HIV Vaccine Studies
We are enrolling HIV-negative volunteers for a number of HIV vaccine studies. The products used in our trials are not produced from live HIV or from HIV-infected human cells and cannot cause HIV infection.
Mucosal Studies
We are enrolling HIV-negative volunteers for studies on how the mucosal immune system works and how people become infected with HIV through sex. Participants will make one clinic visit and provide a swabbed sample from their mucous membranes.
HIV Cohort Studies
We are seeking both HIV-positive and HIV-negative volunteers for observational studies that help us learn more about the immune system. No medications or vaccines will be given.
Conquer the Common Cold
We are currently recruiting about 200 people to participate in our study. We hope that this study may provide information to help with designing a vaccine for Rhinovirus or for other viruses. Rhinoviruses are responsible for causing 30-50% of common colds.
Faculty & Labs
Learn about the hundreds of faculty at Fred Hutch and their groundbreaking research — all of it aimed at eliminating cancer and related diseases as causes of human suffering and death.
Patients have access to world-class cancer treatments developed at Fred Hutch through Seattle Cancer Care Alliance, which brings together research teams and cancer specialists from Fred Hutch, Seattle Children’s and UW Medicine.