Non-Hodgkin Lymphoma at Fred Hutch Cancer Center

Experts in Non-Hodgkin Lymphoma Care 

Each year at Fred Hutch Cancer Center, we care for more than 3,000 patients with non-Hodgkin lymphoma (NHL), including more than 60 rare subtypes. We provide all standard therapies. Our experts are national leaders in NHL research and have developed many of these approaches.

To make sure you get the best clinical care and research opportunities, we bring together a team of NHL experts to discuss and design your treatment. This means you benefit from the experience of the whole group.

Many of our patients take part in clinical trials — led by world-renowned physicians from Fred Hutch and UW Medicine — to get promising therapies that are not available everywhere. Through efforts like the Immunotherapy Integrated Research Center, we’re at the forefront of a fundamental shift in the way cancer is treated and cured, empowering a patient’s immune system to fight cancers like lymphoma.

Non-Hodgkin Lymphoma Information

Lymphoma starts when a type of white blood cell called a lymphocyte changes and grows out of control. Sometimes the disease is indolent and grows slowly, which may cause fewer symptoms. Sometimes it is aggressive and grows quickly. This matters for NHL treatment.

Non-Hodgkin Lymphoma Symptoms

Learn about the common signs and symptoms of NHL and how different NHL subtypes may cause different symptoms because of how they affect your lymphocytes, blood, organs or other tissues.

Non-Hodgkin Lymphoma Stages

Physicians group non-Hodgkin lymphoma into stages I (1) through IV (4). Learn more about each stage and why it matters in treatment planning.

Screening and Diagnosis

To diagnose non-Hodgkin lymphoma, physicians take out a sample of tissue, often a lymph node or part of a lymph node, for testing. A hematopathologist checks the sample under a microscope for cancer cells. NHL is usually diagnosed through testing ordered by a patient’s primary care provider. Fred Hutch hematopathologists review pathology to confirm diagnosis and are experts in identifying NHL subtypes.

Treatments and Therapies

Different non-Hodgkin lymphoma subtypes start, grow and respond to treatments differently. Your Fred Hutch care team will tailor your treatment plan based on your NHL subtype, if it’s indolent or aggressive, the stage of the disease and other important factors, like your personal preferences.

Non-Hodgkin Lymphoma Specialists at Fred Hutch

At Fred Hutch, you receive care from a team of providers with extensive experience in NHL. Your care team includes a hematologist-oncologist, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs.

Non-Hodgkin Lymphoma Research and Clinical Trials

In recent decades, research into targeted therapies and immunotherapies has found new ways to control NHL. Physicians and researchers from Fred Hutch and UW Medicine continue to develop and test innovative treatment approaches like these.

Non-Hodgkin Lymphoma Risk Factors and Prevention

Learn about risk factors for non-Hodgkin lymphoma.

Locations for Non-Hodgkin Lymphoma Care

Find expert NHL at Fred Hutch locations. Explore treatment options backed by compassionate, world-class oncology teams.

We know a cancer diagnosis can be overwhelming. Contact us for an appointment or second opinion.

Why Choose Fred Hutch for Non-Hodgkin Lymphoma Care

At Fred Hutch we combine compassionate care with innovative research to address the impact of cancer and infectious disease. We’re driven by the urgency of our patients, the hope of our community and our passion for discovery to pursue scientific breakthroughs and healthier lives for every person. 

Non-Hodgkin Lymphoma News

All news
Dr. Jingyi Jessica Li named Donald and Janet K. Guthrie Endowed Chair in Statistics Funding will help new program head expand applied use of statistics in cancer research October 7, 2025
What's next for T-cell therapies: Q&A with Dr. Stanley Riddell After approval of latest cellular therapy for non-Hodgkin lymphoma, the immunologist looks ahead February 5, 2021
Antibody blocks Epstein-Barr virus in preclinical trial Hutch-discovered protein blocks virus linked to cancers, mono, autoimmune diseases June 23, 2020