Every investigator at Fred Hutch has access to shared facilities and cutting-edge technologies and expertise that can help speed the process of discovery — and that few individual labs could afford on their own. This multimillion-dollar infrastructure is also accessible to members of the Cancer Consortium, academic and industry research partners, and some other external clients. Our shared resources include core facilities that are staffed by experts who can help investigators design experiments, choose the most suitable tests and equipment, create customized tests and software tools, and analyze experimental results. In all, they offer dozens of services in addition to access to equipment and tools.
This shared resource provides custom-designed monoclonal antibodies, antigen design, immunization and screening strategies, and hybridoma cell line production and optimization.
This shared resource is staffed by bioinformatics specialists who help researchers process, explore and understand genomics data and develop new tools and techniques.
The shared resource provides collaborative statistical support to investigators and research projects.
This shared resource is the largest and most comprehensive facility of its kind in Washington state and supports both fundamental and preclinical projects. It is also the only local microscopy facility that offers cryo-techniques. Our light microscopy capabilities include screening for cancer drugs, live cell assays for the development of CAR T cell–based therapies and multi-photon microscopy.
This shared resource provides a series of core services to support investigators and projects at Fred Hutch, and across the Cancer Consortium. Core services include programming, data Control and interviewing, and ancillary services such as tracking participants who are lost to follow up, and mathematical modeling.
This facility is fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care and complies with all U.S. Department of Agriculture, Public Health Service, Washington state and local area animal welfare regulations.
This shared resource provides a broad range of histology, histochemistry, immunochemistry and pathology services, including a wide range of special stains. The Experimental Histopathology team has extensive experience working with human tissue as well as other experimental model systems.
This shared resource offers a wide array of cell analysis and cell sorting instrumentation — from single-laser benchtop analyzers to complex multi-laser cell sorts for cell analysis and sorting — as well as expert technical staff who offer consulting on process-related matters, including experimental design, data analysis and troubleshooting.
This shared resource supports the generation of genomics-based data through DNA array, genetic analysis and high-throughput screening.
This shared resource supports studies of cellular immunity, including assays of cell populations and responses in clinical trials.
This shared resource provides a broad range of metabolomics services including sample analysis, data analysis and interpretation, training and workshops through its specialty cores which include Mass Spectrometry, NMR and Metabolic Imaging, Biostatistics & Bioinformatics, and Promotional & Outreach.
This is a collaborative resource dedicated to increasing the availability of high quality annotated human biospecimens that meet the detailed requirements of translation research and abide by all applicable human subjects regulations.
This is a state of the art exercise facility, a human nutrition laboratory for feeding studies and a clinical facility that conducts study interviews, collects medical history and physical exam data, and supports biospecimen collection, indirect calorimetry, and body composition for single-facility or custom multiple-facility use studies.
This shared resource provides support for characterizing proteins and peptides by mass spectrometry and high-performance liquid chromatography.
This shared resource provides provides state of the art tissue microarray (TMA) construction and analysis services in addition to pathology review of solid tumor specimens for research.
This shared resource provides a wide range of services, including processing of blood, urine and buccal specimens; DNA extractions and DNA fingerprinting; specimen storage options; and tissue culture of B cells.
This shared resource offers development and manufacturing expertise for novel biological molecules, as well as innovative cell-based therapies for preclinical studies and Phase 1/2 clinical testing.
This is a joint Fred Hutch and UW Department of Radiology providing support for the application of technologies for in-vivo biological assessment and imaging in animal models. Imaging modalities include magnetic resonance imaging (MRI) scanners, fluorescence imaging system (Xenogen) bioluminescence capabilities and more.
Shared resources are critical to Fred Hutch’s five-year strategic plan, which calls for an increase in interdisciplinary research that cuts across divisional boundaries. To help teams access emerging technologies — a key component of the strategic plan — these centralized facilities invest in cutting-edge equipment and tools. Importantly, junior and senior faculty members have equal access. This approach offers huge benefits to groups such as our integrated research centers, which includes faculty from all five Fred Hutch scientific divisions.