Excellence in Preclinical Research
The Comparative Medicine shared resource provides a variety of research support services. All our facilities are fully accredited by the AAALAC International and comply with all U.S. Department of Agriculture, Public Health Service, Washington state and local area regulations.
Our Services
Comparative Medicine Services
We offer expert services for research studies using preclinical models, with offerings in model development, colony management, care, genotyping, imaging, research and diagnostic pathology, training and more.
World-Class PDX Services
Our PDX experts have created xenograft models of dozens of cancers, including Merkel cell carcinoma and cancers of the liver, bladder, lung and pancreas, on behalf of investigators across Seattle and beyond. We’ve performed more than 2,000 xenograft surgeries since 2016.
Cutting-Edge Genome Engineering
Our GEMM team designs, produces and maintains transgenic and gene-edited mice in partnership with investigators pursuing a variety of research questions. Our high editing efficiency — up to 100% of live-born pups in our projects exhibit successful gene targeting — is testament to our expertise in CRISPR/Cas9 and other state-of-the-art genome engineering technologies.
Our Team at Work
The Comparative Medicine team’s excellence in operational, veterinary and research support services enables high-quality science that proceeds with maximal efficiency, care and regulatory compliance. Our veterinary and research teams provide collaborative support in study design, IACUC protocol review, project-specific training and implementation, and assistance. Our operations teams ensure animals are optimally cared for through stringent husbandry practices.
A Comparative Medicine core staff member prepares equipment.
A bulk rack washer ensures consistent sanitation processes.
Staff removes clean water bottles from tunnel washer.
A Comparative Medicine core staff member prepares equipment.
A bulk rack washer ensures consistent sanitation processes.
Staff removes clean water bottles from tunnel washer.
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