Core Facilities

Supporting Breakthrough Science

Every investigator at Fred Hutch has access to shared facilities and cutting-edge technologies and expertise that can help speed the process of discovery — and that few individual labs could afford on their own. This multimillion-dollar infrastructure is also accessible to members of the Fred Hutch/University of Washington Cancer Consortium, academic and industry research partners, and some other external clients. Shared Resources core facilities are staffed by experts who can help investigators design experiments, choose the most suitable tests and equipment, create customized tests and software tools, and analyze experimental results. In all, they offer dozens of services in addition to access to equipment and tools.

Antibody Technology

Provides custom-designed monoclonal antibodies, antigen design, immunization and screening strategies, and hybridoma cell line production and optimization.

Cellular Imaging

The largest and most comprehensive shared microscopy facility in the region; supports both basic and preclinical projects.

Comparative Medicine

Fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care and complies with all animal welfare regulations.

Cryo-EM

Offers services in cryogenic electron microscopy to solve difficult molecular structures at an ultra-fine scale. 

Data Core

Offers training, consulting and infrastructure for hybrid high-performance computing, scientific software, database services and petabyte-scale data management.

Experimental Histopathology

Provides a range of histology, histochemistry, immunochemistry and pathology services for human tissues and model organisms.

Flow Cytometry / CyTOF

Offers top-of-the-line cell analysis and cell-sorting services, from single-laser benchtop analysis to mass cytometry and complex multi-laser cell sorts.

Genomics / Bioinformatics

Provides integrated support to generate and analyze genomic data from DNA array, genetic analysis and high-throughput screening methods.

Immune Monitoring

Supports studies of cellular immunity, including assays of cell populations and responses in clinical trials.

Preclinical Modeling

Supports the development and maintenance of preclinical mouse models, including patient-derived xenografts, cell-line xenografts and genetically engineered mouse models.

Proteomics

Provides mass spectrometry and high-performance liquid chromatography services for the analysis of proteins and peptides, including metabolomics studies.

Specimen Processing / Research Cell Bank

Processes blood, urine and buccal specimens, and offers DNA extraction and fingerprinting, specimen storage and B cell tissue culture.

Therapeutic Products Program

Offers development and manufacturing expertise for novel biological molecules and cell-based therapies for preclinical studies and Phase 1/2 clinical testing.

Shared Resources Operations

Responsible for the strategic optimization and effective day-to-day functioning of the core facilities, including strategic leadership, finance and business operations, facilities and informatics development and organizational business integration.

The Thomas Building on the Fred Hutch main campus is home to many of our Shared Resource core facilities. Photo by Robert Hood / Fred Hutch News Service