The Electron Microscopy shared resource offers techniques that allow researchers to resolve structures from cellular ultrastructure all the way down to molecular interactions. Our expertise in EM sample preparation and imaging allows us to support biomedical and translational research. With our cryogenic electron microscopy, or cryo-EM, technologies and services, the core brings a new structural determination technique to solve difficult molecular structures at an ultrafine scale. Recent advances in cryo-EM technology and software algorithms have made it a compelling structural biology method for flexible proteins that resist visualization by other techniques.
We offer services and one-on-one training through the complexities of the electron microscopy workflow, from sample preparation to image processing. All users are supported by experienced staff members and will be granted 24/7 access to instruments after they have satisfied training requirements. Our equipment, training, and services are available to both internal and external users.