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Acute Effects of Exercise on Breast Cancer Biomarkers (ACE) Study

Public Health Sciences, Epidemiology

The Acute Effects of Exercise on Breast Cancer Biomarkers (ACE Study) is enrolling women to test the effect of moderate intensity exercise on cancer risk factors such as biomarkers in healthy women. Knowing if exercise significantly alters these biomarkers, could help support guidelines for daily exercise for breast cancer prevention and could indicate that exercise even without weight loss is beneficial.

Contact: Jude Warner, acestudy@fredhutch.org

Advanced Colorectal Cancer of Serrated Subtype (ACCESS) Study

Public Health Sciences, Cancer Prevention

Researchers are studying a subtype of colorectal cancer (CRC) that develops via the serrated pathway with a goal of determining future prevention strategies and advancing treatment for CRC.

Funding Agency: National Institutes of Health

Contact: Rachel Malen, rmalen@fredhutch.org

Advancing our Understanding of the Etiologies and Mutational Landscapes of Basal-like, Luminal A, and Luminal B Breast Cancer

Public Health Sciences, Epidemiology

Addressing research gaps in the molecular subtypes of breast cancer, we are taking a multidisciplinary approach to study the epidemiology and mutational landscapes of basal-like, luminal A, and luminal B tumors.

Funding Agency: DOD

Contact: Sarah Taylor, sataylor@fredhutch.org

Ancillary Cost-Effectiveness Analysis

Public Health Sciences, Cancer Prevention

Researchers are determining the cost-effectiveness of cord blood vs. haplo matched relatives using clinical information from the Bone Marrow Transplant (BMT) Clinical Trials Network (CTN) and insurance claims data.

Funding Agency: National Institutes of Health

Contact: Jordan Steelquist, jsteelq@fredhutch.org

Bacterial Correlates of Colorectal Cancer Subtypes and Survival

Public Health Sciences, Epidemiology

Scientists identify differences in the bacterial community in tumors for patients with etiologically-distinct subgroups of colorectal cancer, and how those differences relate to survival.

Funding Agency: National Cancer Institute

Contact: Amanda Phipps, aphipps@fredhutch.org

Breast Cancer Initiative 2.5

Public Health Sciences, Epidemiology

Breast Cancer Initiative 2.5 is uniting the global breast cancer community behind a common goal to make breast health a global priority and reduce disparities in breast cancer outcomes for 2.5 million women by 2025.

Breast, Colorectal and Ovary Cancer Clinical Validation Center

Public Health Sciences, Epidemiology

After identifying early detection biomarkers for each of these cancers, we are conducting phase 2 and phase 3 validation studies directed towards clearly defined clinical applications.

Funding Agency: National Cancer Institute

Contact: Chris Li, cili@fredhutch.org

Carotene and Retinol Efficacy Trial (CARET)

Public Health Sciences, Cancer Prevention

Researchers tested the efficacy and safety of beta-carotene and retinyl palmitate in people at high risk for lung cancer in a randomized, double-blind, placebo-controlled trial. Active follow-up of trial. participants ended on June of 2005; however, the program continues to support the extensive biological repository and ancillary studies that use CARET samples and data.

Contact: Jackie Dahlgren, jdahlgre@fredhutch.org

Case-control study of ovarian cancer (DOVE)

Public Health Sciences, Epidemiology

Using two ovarian cancer case-control studies, scientists are trying to determine why some women develop ovarian tumors and others do not.

Funding Agency: National Cancer Institute

Contact: Holly Harris, hharris@fredhutch.org

Chronic Myelogenous Leukemia Care in the Tyrosine Kinase Era

Public Health Sciences, Epidemiology

Using the Optum Labs/United Healthcare database, investigators review healthcare use patterns of chronic myelogenous leukemia patients treated in the tyrosine kinase inhibitor era.

Funding Agency: American Association for Cancer Research (AACR)

Contact: Nancy Blythe, nblythe@fredhutch.org

Last Modified, April 12, 2021