Assessing Diet, Appetite and Physiology Throughout Weight Loss
Why does weight loss stop?
People can achieve weight loss through lifestyle changes, but often weight loss stops despite efforts to continue losing weight.
The ADAPT study is interested in learning why weight loss stops and if body and brain changes can predict halted weight loss, known as an involuntary weight loss plateau.
The study lasts about 18 months and includes in-person visits at the University of Washington South Lake Union campus and Fred Hutch. During the first 6-months of the study, participants will complete a weight loss program focused on reducing dietary intake and increasing physical activity. The program is held by teleconference (e.g., Zoom) and involves group and one-on-one discussion sessions that are led by Fred Hutch nutrition staff. Individuals in similar programs have lost 5-7% of their body weight.
The weight loss program and all study visits are provided by the study at NO COST to participants. Participants could receive up to $550.
Study Activities
Key Eligibility Criteria
- 18-60 years old
- BMI between 30-50 kg/m2
- Willing to attend in-person study visits and participate in remote weight loss intervention
- No major medical conditions
- Not in a weight loss program
- Not taking prescription medications for weight loss
- Able and willing to have MRIs and muscle and adipose tissue biopsies
Research Study Team
Marian Neuhouser, PhD, RD
Ellen Schur, MD, MS
