Cancer Prevention Program
The Cancer Prevention Program is built around the idea that changing certain lifestyle or environmental factors can lower cancer incidence and improve survival. We investigate cancer etiology and risk factors through clinic- and community-based studies in targeted populations.
As part of our long-term objectives, we develop and test novel screening and surveillance methods that can be readily translated into clinical practice and train the next generation of scientists in prevention research.
Cancer Prevention Faculty
Our faculty members research genetic, environmental, nutritional, and behavioral factors that can reduce cancer morbidity and mortality rates.
Active Projects
Advanced Colorectal Cancer of Serrated Subtype (ACCESS) Study
Public Health Sciences, Cancer PreventionResearchers are studying a subtype of colorectal cancer (CRC) that develops via the serrated pathway with a goal of determining future prevention strategies and advancing treatment for CRC.
Funding Agency: National Institutes of Health
Contact: Rachel Malen, rmalen@fredhutch.org
Ancillary Cost-Effectiveness Analysis
Public Health Sciences, Cancer PreventionResearchers are determining the cost-effectiveness of cord blood vs. haplo matched relatives using clinical information from the Bone Marrow Transplant (BMT) Clinical Trials Network (CTN) and insurance claims data.
Funding Agency: National Institutes of Health
Contact: Jordan Steelquist, jsteelq@fredhutch.org
Cancel Save & Close Menopause Strategies: Finding Lasting Answers for Symptoms and Health (MsFLASH)
Public Health Sciences, Cancer PreventionThe MsFLASH network conducts clinical trials aimed at finding promising treatments for the most common symptoms of menopause.
Carotene and Retinol Efficacy Trial (CARET)
- Marian Neuhouser, Ph.D. R.D.
- Mark Thornquist, Ph.D.
- Gary Goodman, M.D.
- Charles Kooperberg, Ph.D.
- Noel Weiss, M.D., Dr.P.H.
- Chu Chen, Ph.D.
Researchers tested the efficacy and safety of beta-carotene and retinyl palmitate in people at high risk for lung cancer in a randomized, double-blind, placebo-controlled trial. Active follow-up of trial. participants ended on June of 2005; however, the program continues to support the extensive biological repository and ancillary studies that use CARET samples and data.
Contact: Jackie Dahlgren, jdahlgre@fredhutch.org
Clinical and Economic Value of Next Generation Sequencing-Based Diagnostic Testing in Cancer Care
Public Health Sciences, Cancer PreventionResearchers are developing a decision model designed to evaluate the cost effectiveness of multiplex NGS testing vs. usual care. They plan to pair the decision model with information theory to identify the most efficient and impactful study designs.
Funding Agency: Personalized Medicine Coalition
Contact: Jordan Steelquist, jsteelq@fredhutch.org
Collaboration for a Healthy Community (Together We STRIDE)
Public Health Sciences, Cancer PreventionThe goal of the project is to build and enhance community capacity and infrastructure on childhood obesity initiatives in the Lower Yakima Valley, Washington.
Funding Agency: National Institute on Minority Health and Health Disparities
Contact: Sonia Bishop, sbishop@fredhutch.org
Colorectal Research in Epidemiology (CORE) Family Studies
Public Health Sciences, Cancer PreventionWorking with biological specimens, medical records and interviews, researchers investigate how genetic, environmental and lifestyle factors effects the incidence of colon and rectal cancers.
Funding Agency: National Institutes of Health
Contact: Rachel Malen, rmalen@fredhuthc.org
Cook for Your Life!: Maintaining Diet and Physical Activity
Public Health Sciences, Cancer PreventionTo test the effects of in-person and e-communication (e.g., text, email) interventions on improving diet and physical activity among Latina breast cancer survivors.
Funding Agency: National Institutes of Health / National Cancer Institute
Contact: Lisa Levy, llevy@fredhutch
Cost Effectiveness Analysis of Stem Cell Transplant in Older MDS Patients
Public Health Sciences, Cancer PreventionResearchers compare the differences in cost and quality of life when using allogeneic stem cell transplant versus hypomethylating agents for patients aged 50 to 75 with myelodysplastic syndrome.
Funding Agency: National Institutes of Health
Contact: Jordan Steelquist, jsteelq@fredhutch.org
Diet and Genetic Risk for Prostate Cancer
Public Health Sciences, Cancer PreventionUsing the data from the 12,000 Carotene and Retinol Efficacy Trial (CARET) participants, this study looks at the effects of both diet and dietary supplements, as well as polymorphisms in oxidative stress regulatory genes, on prostate cancer risk.
Funding Agency: National Cancer Institute
Contact: Diana Lowry, dlowry@fredhutch.org
Early Detection Research Network (EDRN)
Public Health Sciences, Cancer PreventionThe Data Management and Coordinating Center (DMCC) of the EDRN is jointly operated by Fred Hutch, the University of Washington, the University of Texas MD Anderson Cancer Center and COMPASS. It provides coordination and data management under the direction of the Steering Committee and develops statistical and analytical methods based for the network.
Funding Agency: National Institutes of Health
Contact: Royce Malnik, rmalnik@fredhutch.org
Enhancing And Teaching [EAT] 5 for Life Project
Public Health Sciences, Cancer PreventionThis study builds on the Seattle 5 a Day Worksite Program and studies the effectiveness of interventions designed to maintain the changes companies made with the original project.
Contact: Sonia Bishop, sbishop@fredhutch.org
FRESH Study
Public Health Sciences, Cancer PreventionFRESH study researchers are exploring how meal frequency affects the body. By comparing biomarkers in people who eat three times per day to those who eat six times per day, they’re hoping to determine which eating pattern is more beneficial.
Funding Agency: National Institutes of Health
Contact: Diana Lowry, dlowry@fredhutch.org
Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO)
Public Health Sciences, Cancer PreventionThrough the collaborative effort of researchers from three continents, GECCO researchers study the impact of common and rare genetic variants across the entire genome by performing whole genome sequencing and genotyping. They also align detailed clinical, epidemiologic, and outcome data across the studies in the consortium.
Funding Agency: National Institutes of Health
Contact: Tabitha Harrison, tharriso@fredhutch.org
Geographic Management of Cancer Health Disparities (GMAP)
Public Health Sciences, Cancer PreventionThe Geographic Management of Cancer Health Disparities Program (GMaP) is a systematic and comprehensive approach to facilitating collaboration and capacity-building among cancer health disparities researchers and organizations to advance cancer health disparities research and training.
Contact: Sara Cole, scole2@fredhutch.org
Health and Behavioral Innovations in Technology (HABIT) Group
Public Health Sciences, Cancer PreventionThe HABIT group develops technology-based interventions to help people make healthier choices, liking quitting smoking, eating healthy and losing weight.
Contact: Brie Sullivan, bsulliva@fredhutch.org
Health, Eating, Activity and Lifestyle (HEAL) Study
Public Health Sciences, Cancer PreventionThis study covered a multiethnic group of breast cancer survivors from western Washington, Los Angeles County, and north-central New Mexico. Within 12 months of a diagnosis, women completed a baseline interview. Two years later, they completed a second interview, with a blood draw, anthropometry, and diet and dietary supplement questionnaires.
Funding Agency: National Cancer Institute
Contact: Diana Lowry, dlowry@fredhutch.org
Metabolically Activated Macrophages in Obesity and Insulin Resistance
Public Health Sciences, Cancer PreventionResearchers explore how adipose tissue macrophages contribute to insulin resistance in obese patients, in a study designed to dissociate the relationship between adiposity, adipose tissue inflammation, and insulin resistance.
Funding Agency: National Institutes of Health
Contact: Gail Cromer, gcromer@fredhutch.org
Move and Moderate in Balance (MOVE'M) Study
Public Health Sciences, Cancer PreventionProject involves more than a dozen organizations focused on increasing the access to healthy foods and physical activity at the work place. This two-year study is designed to be maintained after the close of the study period.
Contact: Sonia Bishop, sbishop@fredhutch.org
New-Onset Diabetes (NOD)
Public Health Sciences, Cancer PreventionThe New-Onset Diabetes (NOD) cohort is jointly funded by NCI and NIDDK and is part of the Consortium for the study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC).
Contact: Sarah Nguyen, sarah-nguyen@fredhutch.org
Nutrition Assessment Shared Resources (NASR)
Public Health Sciences, Cancer PreventionThe NASR helps investigators bring state-of-the-art dietary data collection methods into their research protocols. In-house processing of dietary data allows for a high degree of standardization, rigorous quality assurance procedures, control of data management and maximum flexibility to nutrient databases.
Contact: Carolyn Ehret, cehret@fredhutch.org
Nutrition and Physical Activity Assessment Study (NPAAS)
Public Health Sciences, Cancer PreventionThis study uses biomarker measurements to correct for differences in actual diet and activity versus self-reported intake and output levels. By tracking objective measurements, they’re better able to identify risk factors for many cancers, cardiovascular disease and diabetes that are typically not apparent with self-reporting.
Funding Agency: National Cancer Institute
Contact: Sheri Greaves, sgreaves@whi.org
Partnership for the Advancement of Cancer Research (PACR) Project
Public Health Sciences, Cancer PreventionFred Hutch has partnered with New Mexico State University in a program funded by the national Cancer Institute’s Partnerships to Advance Cancer Health Equality (PACHE) program. Scientists work with institutions in underserved communities to train students from diverse backgrounds in cancer research while effectively delivering cancer advances to racially and ethnically diverse communities.
Funding Agency: National Cancer Institute / Partnerships to Advance Cancer Health Equity
Contact: Marilyn Drennan, mdrennan@fredhutch.org
Population Architecture using Genomics and Epidemiology (PAGE)
Public Health Sciences, Cancer PreventionResearchers investigate whether genetic variants initially identified through genome-wide association study (GWAS) research are generalizing across ancestral groups, modified by environmental factors and associated with various outcomes.
Funding Agency: National Institutes of Health
Contact: Tabitha Harrison, tharriso@fredhutch.org
Contact Cancer Prevention
Program Operations Director
Kelly Ambrose
Phone: 206.667.7726
kambrose@fredhutch.org
Assistant to the Program Head
Elizabeth Cox
Phone: 206.667.5755
eacox@fredhutch.org
Location
The Cancer Prevention Program is located at the Robert W. Day Campus in the South Lake Union neighborhood of Seattle.
Mailing address:
Fred Hutchinson Cancer Research Center
Cancer Prevention Program
1100 Fairview Ave N, M3-B232
P.O. Box 1024
Seattle, WA 98109-1024
The UW Box number is 35808. When using box number, follow with mail stop.