Since its initial inception in 1983, the Cancer Prevention Program has grown into the largest and most diverse program in PHS with expertise in epidemiology, biostatistics, nutrition, genomics, behavioral science, health economics, health disparities, health communications, dissemination and implementation, primary care and oncology. Through interdisciplinary collaborations, CP faculty and staff are dedicated to the mission of preventing chronic disease and its consequences by identifying exposures, understanding mechanisms, and developing effective interventions. Faculty members frequently conduct laboratory-based investigations related to risk, exposure and biomarker assessment that inform interventions. We continue to be at the forefront of nutrition and cancer research.
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Carlson Studies
The Carlson group uses genetic epidemiology to investigate the genetic risk factors of diseases such as cancer, cardiovascular and neurological disease. The molecular biology lab explores the underlying molecular mechanisms behind these correlations.
Grady Lab
The Grady Lab is focused on the role of genomic and epigenomic alterations in gastrointestinal carcinogenesis, specifically esophageal adenocarcinoma (EAC) and colorectal cancer (CRC).
Greenlee Studies
The Greenlee group focuses on behavioral interventions for cancer prevention and control as well as validating and testing complementary and integrative approaches to cancer survivorship. In essence, we want to understand what cancer survivors can do, in addition to conventional care, to improve cancer outcomes.
Health Communication Research Center
Health Communication Research Center (HCRC) develops, tests, evaluates and disseminates theory-based health communication interventions using various media including prints, podcasts, internet websites, and social media.
Health and Behavioral Innovations in Technology
Health and Behavioral Innovations in Technology (HABIT) designs, develops, tests, and disseminate techology-delivered interventions for health behavior change. Our goals are to develop and test technologies to help one million people quit smoking, eat healthy and lose weight.
Jones Lab
The Jones Lab research focuses on understanding financial hardship and financial anxiety affect health, quality of life and disease outcomes and testing unique methods of interpreting patient-reported outcomes to measure effectiveness of clinical care and adapt methods for use in oncology clinical trials.
Neuhouser Lab
The Neuhouser Lab's research focuses on investigating the role of modifiable lifestyle factors, including nutrition, physical activity and energy balance/obesity and their relationship to the etiology and prevention of cancer. Research investigates methodologies to improve upon dietary self-report, novel methods to characterize food intake, innovative intervention strategies and applications to large cohorts with well-characterized and adjudicated clinical outcomes.
Peters Lab
The peters Lab is studying the impact of genetic variants across the genome, as well as interactions of genetic variants with lifestyle and environmental risk factors. We are also conducting large-scale studies to analyze molecular and genetic characteristics of colorectal tumors and their microenvironment in relation to host genomes, lifestyle and environmental risk factors, and survival.
Tobacco-Related Health Disparities Research Group
The Tobacco-Related Health Disparities (TREHD) Research Group focuses on research to improve treatment for tobacco-related health disparities groups — including people with mental health conditions and Veterans receiving care through the Veterans Health Administration (VHA) — by testing new treatment content and increasing treatment accessibility through high-reach delivery modalities of telephone, web and mobile.
Hutchinson Institute for Cancer Outcomes Research
Office of Community Outreach & Engagement
SWOG
Women's Health Initiative
Hutchinson Institute for Cancer Outcomes Research
Hutchinson Institute for Cancer Outcomes Research (HICOR) is a research institute at Fred Hutch whose mission is to improve cancer prevention, detection and treatment in ways that will reduce the economic and human burden of cancer — and ultimately lead to better outcomes for patients. To achieve this, HICOR brings together researchers, patient partners, clinicians, payers and policymakers to share cancer-related data and generate clinically relevant performance metrics that can guide improvements in cancer care.
ADAPT Study
Public Health Sciences, Cancer PreventionThe ADAPT study is interested in learning why weight loss stops and if body and brain changes can predict halted weight loss, known as an involuntary weight loss plateau. The study lasts about 18 months and includes in-person visits at the University of Washington South Lake Union campus and Fred Hutch.
Advanced Colorectal Cancer of Serrated Subtype (ACCESS) Study
Public Health Sciences, Cancer PreventionResearchers are studying a subtype of colorectal cancer (CRC) that develops via the serrated pathway with a goal of determining future prevention strategies and advancing treatment for CRC.
Funding Agency: National Institutes of Health
Contact: Rachel Malen, rmalen@fredhutch.org
Ancillary Cost-Effectiveness Analysis
Public Health Sciences, Cancer PreventionResearchers are determining the cost-effectiveness of cord blood vs. haplo matched relatives using clinical information from the Bone Marrow Transplant (BMT) Clinical Trials Network (CTN) and insurance claims data.
Funding Agency: National Institutes of Health
Contact: Jordan Steelquist, jsteelq@fredhutch.org
Cancel Save & Close Menopause Strategies: Finding Lasting Answers for Symptoms and Health (MsFLASH)
Public Health Sciences, Cancer PreventionThe MsFLASH network conducts clinical trials aimed at finding promising treatments for the most common symptoms of menopause.
Carotene and Retinol Efficacy Trial (CARET)
- Marian Neuhouser, PhD, RD
- Matty Triplette, MD, MPH
- Mark Thornquist, PhD
- Gary Goodman, MD
- Chu Chen, PhD
Researchers tested the efficacy and safety of beta-carotene and retinyl palmitate in people at high risk for lung cancer in a randomized, double-blind, placebo-controlled trial. Active follow-up of trial. participants ended on June of 2005; however, the program continues to support the extensive biological repository and ancillary studies that use CARET samples and data.
Funding Agency: National Cancer Institute
Contact: Becky Harbine, bharbine@fredhutch.org
Clinical and Economic Value of Next Generation Sequencing-Based Diagnostic Testing in Cancer Care
Public Health Sciences, Cancer PreventionResearchers are developing a decision model designed to evaluate the cost effectiveness of multiplex NGS testing vs. usual care. They plan to pair the decision model with information theory to identify the most efficient and impactful study designs.
Funding Agency: Personalized Medicine Coalition
Contact: Jordan Steelquist, jsteelq@fredhutch.org
Collaboration for a Healthy Community (Together We STRIDE)
Public Health Sciences, Cancer PreventionThe goal of the project is to build and enhance community capacity and infrastructure on childhood obesity initiatives in the Lower Yakima Valley, Washington.
Funding Agency: National Institute on Minority Health and Health Disparities
Contact: Sonia Bishop, sbishop@fredhutch.org
Colorectal Research in Epidemiology (CORE) Family Studies
Public Health Sciences, Cancer PreventionWorking with biological specimens, medical records and interviews, researchers investigate how genetic, environmental and lifestyle factors effects the incidence of colon and rectal cancers.
Funding Agency: National Institutes of Health
Contact: Rachel Malen, rmalen@fredhuthc.org