Shared Resources Job Openings

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Shared Resources (SR) Department of Research Administration (RA) Fred Hutch supports the faculty and research community through interdisciplinary sciences to accelerate innovation discovery by enabling scientific collaboration through unparalleled infrastructure including the Shared Resources supports.

Under the direction of the Administrative Manager, the Administrative Assistant II will provide support to more than 14 scientific core that works with an employee base of approximately 330 people. The Shared Resources Administrative (SR Admin) team provides Core facilities with business support in areas including operations, fiscal management, billing, fund development, and HR. The candidate will work collaboratively across RA, the Administration Division, and Scientific Divisions. This position has the potential to be a hybrid work model.

Responsibilities

This key administrative position is responsible for supporting, organizing and coordinating activities for SR operations which includes Shared Resources Senior Directors, Core Directors, and the admin team. The incumbent works independently in performing responsibilities. This role requires strong organizational and time management skills, attention to detail, the ability to effectively prioritize shifting tasks, and to build strong working relationships. Judgment is used daily in interpreting policy, representing the department, interacting with Center staff, and working with highly sensitive or confidential information. Critical qualities also include exceptional written and oral communication, critical thinking, and teamwork. Responsibilities include:

• Function as a primary contact person for Shared Resources. Act as a liaison with Fred Hutch staff and outside individuals/organizations, answering questions, monitor shared inboxes, and resolving problems with regards to the administration of the department/project(s)/program/initiatives.
• Perform administrative and clerical duties including
  • scheduling meetings, conferences and seminars
  • assembling meeting agendas
  • collecting and compiling a variety of information
  • composing minutes reports and memos
  • office organization
  • travel agendas
  • establishing and maintaining department files in hard copy and electronic form
  • Purchasing equipment and supplies for the program and performing inventory control duties; Working with purchasing department as required.
• Arranges travel agendas and requirements, and activities as required by the leadership; performs clerical duties to include preparation of correspondence
• Assist with onboarding new hires by scheduling introductory meetings, arranging communication/meeting access and IT support
• Maintain workflows and database for scientific equipment
• Assist the Sr. Operations Manager, leadership, and staff with the implementation and administration of institution, and department projects/programs/initiatives, policies and procedures. Assist the leadership with the implementation and administration of Center and department policies and procedures.
• Assist with planning, production, printing, and distribution of department communications and newsletters
• Coordinate special events including holiday party, tours, poster sessions, open house, and coffee chats
• Manage and process reimbursements, and credit card reconciliation
• Perform other duties and special projects assigned

Qualifications

Minimum qualifications:

• Bachelor's degree or equivalent work experience - additional experience may substitute for educational requirement
• Minimum five years of progressively complex administrative experience
• Superior organizational skills and must be detailed
• Strong computer and word processing skills
• Knowledge in Microsoft Office Suite skills (i.e., Excel, Outlook, PowerPoint, Teams, Word), SharePoint, and Adobe Acrobat Pro
• Collaborative and team-oriented communication style able to work effectively cross-departmentally
• Excellent verbal and written communication skills, including the ability to propose actions, identify and illustrate opportunities, and make recommendations
• Able to grasp and apply new concepts quickly
• Ability to effectively prioritize concurrent responsibilities and meet timelines
• Ability to work independently under minimal supervision with a wide degree of creativity and latitude

Preferred qualifications:

• High level of integrity and discretion including the ability to exercise good judgment and maintain confidentiality
• Strong organizational skills, attention to detail and accuracy, flexible with the ability to effectively manage time and prioritize multiple concurrent responsibilities
• High level of initiative. Able to work independently with minimal supervision, and collaborate with a team to effectively to meet deadlines.
• Strong technical aptitude to quickly learn new systems and applications, and able to apply technology to improve systems and processes

Application instructions:

Please submit your resume along with a statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career, or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

This position is responsible for Quality Control (QC) cGMP testing activities in support of Human Gene Therapy Phase I/II clinical trials.  

This position will primarily focus on performing transfer, qualification, and validation of analytical test methods using FDA and ICH guidelines. In addition, the position will perform testing as needed in support of the Cell Processing and Biologics Production facilities (CPF and BPF). Cross-training on multiple assays will be required for this position as well as in laboratory quality systems.

Responsibilities

• Lead and participate in analytical method transfer/qualification/validation activities
• Participate in commissioning of laboratory instrumentation
• Perform cGMP in-process, lot release, and stability testing of raw materials, intermediates, drug substance, drug product, and human gene therapy products
• Review assays performed by peers
• Perform deviation and out of specification (OOS) investigations
• Write SOPs and test methods
• Perform general laboratory activities in accordance to SOPs and laboratory quality systems

Qualifications

MINIMUM QUALIFICATIONS:

• Bachelor’s or Graduate degree in a life sciences field
• Minimum of 4 years (2 years for Graduate Degree) work experience, preferably with a background in biologics and/or cell therapy
• Knowledge of regulatory guidance documents/information for Analytical Procedures and Method Validation
• Experience with ELISA, qPCR, gel electrophoresis, and HPLC methods
• Good written and oral communication. Good presentation skills
• Detail oriented, organized, proactive and self-motivated
• Possess strong communication and teamwork skills
• Ability to analyze data, assess/evaluate trends and make recommendations for improvement
• Experience with typical Quality Systems (ex. Document Control, Deviations, CAPA, Change Control, etc.)

PREFERRED QUALIFICATIONS:

• Knowledge of cGMP requirements for Phase I/II clinical trials
• Familiarity with Chemistry. Manufacturing, and Controls (CMC) information for Investigational New Drug Applications
• Experience with flow cytometry
• Experience with microbial-based assays
• Knowledge of aseptic and cell culture techniques   

A statementdescribing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The Animal Technician I-II performs routine rodent husbandry, custodial care for the animal areas, and processes equipment. The Technician I-II position is overseen by the Animal Technician Lead and is a direct report to the Animal Technician Manager.  This is considered an entry level position for individuals with no prior experience in laboratory animal care procedures or skilled individuals who are transitioning from other animal care positions. The position of tech I-II will be determined depending on experience.

Responsibilities

• Learn to and become proficient in providing care for all small animal species on a daily basis in accordance with standard operating procedures. Learn to evaluate animals’ general health, report abnormalities to the small animal veterinary technologist or veterinarian for veterinary evaluation. Learn to perform preventive animal health care duties and administer treatments as prescribed.
• Learn to and become proficient in
  • providing feed to animals according to prescribed SOPs and insure that animals have fresh water at all times
  • changing animal housing according to schedule by transferring animals to clean housing and transporting soiled housing and accessories to the wash area
  • performing housekeeping duties such as sweeping, mopping, garbage removal, and equipment washing in animal housing areas and surrounding premises
  • maintaining accurate records of animal identification, veterinary treatments, animal census, facility housekeeping, and room parameters (e.g. daily temperature high and low)
  • effectively communicating with research staff regarding the status of their animals through verbal, written, or electronic means
  • Learn to and become proficient in using and maintaining animal housing IVC systems and hoods, including routine cleaning, checking air flow gauges, attaching and removing blower units, securing hoses, and relocating racks to the cage wash facility for sanitizing
  • PPE policies and procedures throughout the small animal vivarium
  • appropriately mix and use of all cleaning solutions according to established SOPs and/or manufacturers’ instructions
  • operation of equipment washers, automatic water bottle filling systems and autoclaves under supervision
  • material management inventory control, notifying the supervisor or designated technicians of items that need to be ordered
• Attend and participate in assigned training classes
• May transport or assist in transport of animals, supplies or equipment between facilities or may assist in such activities
• Work on call, weekend, evening, or holiday shifts as needed or as assigned
• Perform other duties as assigned

Qualifications

• High school diploma or equivalent
• Good verbal and written communication skills
• Ability to follow written and verbal instructions that are presented in English
• Ability to lift and move 50 lbs on a regular basis and sustained physical activities such as bending, balancing, stooping, reaching, and remain standing for long periods of time.
• Ability to wear Personal Protective Equipment including scrubs, gloves, shoe covers, gowns, ear plugs / muffs, face mask, and eye protection
• Science and animal husbandry background preferred

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Fred Hutchinson Cancer Research Center, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, the Center’s five scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Hutchinson Center, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Join us and make a difference!

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

Responsibilities

The Animal Technician I-II performs routine rodent husbandry, custodial care for the animal areas, and processes equipment. The Technician I-II position is overseen by the Animal Technician Lead and is a direct report to the Animal Technician Manager.  This is considered an entry level position for individuals with no prior experience in laboratory animal care procedures or skilled individuals who are transitioning from other animal care positions. The position of tech I-II will be determined depending on experience.

• Learn to and become proficient in providing care for all small animal species on a daily basis in accordance with standard operating procedures. Learn to evaluate animals’ general health, report abnormalities to the small animal veterinary technologist or veterinarian for veterinary evaluation. Learn to perform preventive animal health care duties and administer treatments as prescribed.
• Learn to and become proficient in providing feed to animals according to prescribed SOPs and insure that animals have fresh water at all times.
• Learn to and become proficient in changing animal housing according to schedule by transferring animals to clean housing and transporting soiled housing and accessories to the wash area.
• Learn to and become proficient in performing housekeeping duties such as sweeping, mopping, garbage removal, and equipment washing in animal housing areas and surrounding premises.
• Learn to and become proficient in maintaining accurate records of animal identification, veterinary treatments, animal census, facility housekeeping, and room parameters (e.g. daily temperature high and low).
• Learn to and become proficient in effectively communicating with research staff regarding the status of their animals through verbal, written, or electronic means.
• Learn to and become proficient in using and maintaining animal housing IVC systems and hoods, including routine cleaning, checking air flow gauges, attaching and removing blower units, securing hoses, and relocating racks to the cage wash facility for sanitizing.
• Learn to and become proficient in PPE policies and procedures throughout the small animal vivarium.
• Learn to and become proficient in appropriately mix and use of all cleaning solutions according to established SOPs and/or manufacturers’ instructions.
• Learn to and become proficient in operation of equipment washers, automatic water bottle filling systems and autoclaves under supervision.
• Learn to and become proficient in material management inventory control, notifying the supervisor or designated technicians of items that need to be ordered.
• Attend and participate in assigned training classes.
• May transport or assist in transport of animals, supplies or equipment between facilities or may assist in such activities.
• Work on call, weekend, evening, or holiday shifts as needed or as assigned.
• Perform other duties as assigned.

Qualifications

MINIMUM QUALIFICATIONS:

• High school diploma or equivalent.
• Good verbal and written English communication skills.
• Ability to follow written and verbal instructions that are presented in English.
• Ability to lift and move 50 lbs on a regular basis and sustained physical activities such as bending, balancing, stooping, reaching, and remain standing for long periods of time. 
• Ability to wear Personal Protective Equipment including scrubs, gloves, shoe covers, gowns, ear plugs / muffs, face mask, and eye protection.

PREFERRED QUALIFICATIONS:

• Science and animal husbandry background. 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Bioinformatician II provides specialized consulting and data analysis services to researchers at the Fred Hutch and across the wider FredHutch/UW Cancer Consortium. This position requires the ability to work independently, manage multiple overlapping data analysis projects, and communicate effectively with faculty, post-doctoral fellows, and research staff on a wide range of topics in biology, analysis of next-generation sequencing data, sound experimental design, and data science.

This role will have the opportunity to work partially at our campus and remotely

Responsibilities

The Bioinformatician II reports to the Bioinformatics Shared Resource Manager, in association with the Director of the Genomics & Bioinformatics Shared Resources, and will work with Fred Hutch scientists to refine computational research questions, develop analytical processes applied to large genomic datasets, and provide timely results and documentation for processes used.

• Perform quality control and end-to-end analysis of large sequence datasets from diverse workflows
• Consult with researchers to refine research questions and to develop sound experimental designs
• Identify best-practice bioinformatics tools and strategies to meet the needs of proposed projects
• Provide figures and written sections describing methods and results for manuscripts, presentations, and grant applications
• Partner with researchers who are developing novel assays to design appropriate processing and analysis workflows
• Collaborate with colleagues in the Genomics Shared Resource and the Hutch Data Core to ensure the integrity and consistency of primary data, track experimental methods and metadata, define standardized analysis pipelines, and provide training and support as users analyze and interpret results

Qualifications

• MS or PhD in bioinformatics, computational biology, genetics, or related field
• At least three years’ professional experience with computational analysis of complex sequence-based data sets including some of these assays: whole exome sequencing; targeted amplicon sequencing; somatic variant calling; bulk RNA-seq expression ; single-cell expression and immune repertoire profiling; CUT&RUN; ChIP-seq; ATAC-seq; or CRISPR/Cas9 knockout screens
• Demonstrated fluency in R or Python 3, ideally both
• Proficiency with Linux/Unix shell scripting (e.g., bash)
• Strong organizational skills, including the ability to manage and prioritize multiple competing tasks
• Excellent written and verbal communication skills

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The Bioinformatics Training Specialist is responsible for developing and implementing a broad portfolio of educational resources to support data-intensive science through the Hutch Data Core (HDC). This program focuses on teaching in-person and online short courses in computational and bioinformatic methods to the scientific research community at Fred Hutch. The role includes curating or developing educational content and training documentation to support the efforts of the HDC and its mission to expand the data science capabilities of the UW/Fred Hutch Cancer Consortium research community.

Responsibilities

The Bioinformatics Training Specialist reports to the acting Director of the Hutch Data Core (Sr. Director of the Molecular and Cellular Scientific Resources). The specialist is the lead and primary point of contact for bioinformatics and data-intensive technology training, and is responsible for guiding the planning, implementation, and assessment of all training courses, materials, and one-on-one consultation.

• Oversee all bioinformatics training and educational activities, including the development, maintenance, delivery and ongoing evaluation of institution-wide training content and materials via both in-person and online opportunities
• Work with HDC staff to develop and deliver timely, current and effective institution-wide training in computing and bioinformatics skills
• Work with technology core directors to assess the outreach and educational needs of their user-base
• Work with members of Center IT and Scientific Computing groups on customizing and maintaining educational content specific to the Fred Hutch on-premise and cloud-based computing environment
• Design, develop, and maintain a centralized educational resource supporting courses/seminars, e-libraries, and drop-in consulting both in-person and through online forums such as Slack
• Brand, market, and advertise the available educational offerings by creating a digital presence that brings awareness and draws interest
• Facilitate both a seminar series and a series of group-led “journal club” discussions around current topics in bioinformatics for the Fred Hutch community
• Collaborate with local Slack workspace administrators to create, monitor, and moderate HDC-associated Slack channels as appropriate
• Maintain and update HDC-related content for the Fred Hutch SciWiki
• Define, collect, and report-out training activity metrics to be used to communicate success to the HDC Faculty Advisory Committee and for future inclusion in the UW/Fred Hutch Cancer Consortium Support Grant (CCSG) updates and proposals
• Other responsibilities as needed

Qualifications

• MS or PhD in science education or a pertinent scientific field
• 4+ years of research and/or college-level education teaching
• Demonstrated competency in R, Python, or related language
• Experience with standards and methods in bioinformatics
• Excellent presentation, writing, and editing skills

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism, and inclusion.   

The Department of Research Administration at Fred Hutch supports the faculty and research community through interdisciplinary sciences to accelerate innovation discovery by enabling scientific collaboration through unparalleled infrastructure. The Business Analyst III role will significantly impact the Research Administration business practices at Fred Hutch with complex decision-making with leadership input on the department's business operations. The Research Administration has an annual budget of over $100 million and more than 350 employees. The successful candidate will report to the Director of Finance and Operations in Research Administration work under general Supervision. Under the guidance of the Director of Finance and Operations, the Business Analyst will engage business and clinical leaders and subject domain experts to analyze functional requirements and data sources that support centralizing the Research Administration department businesses. The candidate will work collaboratively across Research Administration, the Administration Division, and Scientific Divisions. This position has the potential to be a hybrid work model.

Responsibilities

The Business Analyst III is a subject matter and process expert; a leader who works with business partners, technical teams, and other stakeholders to design and deliver data and analytics capabilities to support the Research Administration Department and Fred Hutch's mission and strategic goals. Finally, this individual performs a key role in advancing Research Administration to:

• Analyzing the structure and identifying any improvements of business to determine how it operates and determine its objectives within the current business model work. Build systematic solutions that address complex business problems, derive actionable insights, and maximize decision-making confidence while easy to refresh. (25%)
• Design and implement automated analytic solutions, including reports, dashboards, and views from a wide range of data sources, and provide leadership in evaluating, interpreting, and optimizing these solutions. Maintain a solid working knowledge of a wide range of internal financial systems, workflows, and related data sources. (15%)
• Assure integrity of the data for current and future financial reporting and ensure the sustainability and adaptability of all developed solutions. Seek opportunities for continuous improvement. Develop a robust understanding of the Research Administration department's financial data and systems to ensure effective, reliable, and responsible use of data. (15%)
• Collaborate inter-departmentally to monitor and develop meaningful reports that provide users with insight on financial performance. Utilize numerous data sources and analytics to develop reports that assist in conveying the causes of financial variation. Assist in developing action steps for financial improvement and reports to monitor these results. (15%)
• Translate business problems into technical approaches to create standardized Tableau reporting dashboards, which help explain budget to actual variances and guiding decision-making. Partner with
• Operations Analyst to align and enhance existing Tableau Dashboards (15%)
• Manage budget system (currently Kaufman Hall Axiom) from a data management and reporting perspective. Conduct data discovery and analysis from financial data to generate and test working hypotheses, uncover relationships, and identify quality issues. (15%)
• Applies thorough knowledge of the needs of a business unit and understanding of systems technology to identify and design improvements for computer-based systems.
• Conducts operational and organizational studies on business units, analyzes structure and flow of work through the teams, and recommends changes to improve operations.
• Provides consultation to business unit management to determine solutions to business problems.
• Coordinates functional requirements of business unit and technical solutions with systems personnel to develop the most cost-effective solution. Devises test plans, builds test data and tests new or enhanced application functions. Develops and delivers training and operating procedures.
• Have extensive experience in the supported business functions, as well as some data processing skills and knowledge.

Qualifications

MINIMUM QUALIFICATIONS:

• Bachelor's degree in Math, Business, Computer Science or related field, or equivalent combination of education and experience/technical training that demonstrates analytical and technical competency.
• 5 years of business analytic experience.
• Superior organizational skills.
• Proven knowledge and application of best practices for system management, documentation, and standardization.
• Sustained, proven ability to think systematically and analytically using independent judgment.
• Ability to identify and implement improvements such as increasing the level of data accuracy or decreasing the time spent to update a model or report.
• Experience working with financial software programs
• Advanced experience with systems; Tableau, PeopleSoft, Workday.
• Advanced Excel skills.
• Experience with relational database tools such as SQL Server and Access.
• Ability to research, analyze and interpret complex data and formulate recommendations.
• Collaborative and team-oriented communication style with ability to work effectively cross-departmentally.
• Excellent verbal and written communication skills, including the ability to propose actions, identify and illustrate opportunities, make recommendations.
• Solid financial skills, including a working understanding of the income statement.
• Able to grasp and apply new concepts quickly.
• Ability to effectively prioritize concurrent responsibilities and meet timelines.
• Ability to manage projects independently or lead/direct the work of others with a wide degree of creativity and latitude.
• Ability to work in a high-pressure, deadline-oriented, and complex health care environment.
• Working understanding of relations between income statement, balance sheet, and cash flow statement. Articulate the financial impact of decisions to both clinical and administrative audiences.

PREFERRED QUALIFICATIONS:

• Masters degree or higher level degree in Health Science, Informatics, Business, or a related field.
• 8 years of business analytic experience in a healthcare environment
• Expert in managing databases and systems.
• Expert with Tableau.
• Extensive experience in exploratory data analysis, data visualization.
• Experience with predictive modeling and leading indicators

Please submit a cover letter with your application outlining how you meet the qualifications.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The primary responsibility of a Cellular Production Associate is to execute manufacturing operations in the production of modified cellular products for patients participating in clinical protocols using cellular therapy. Clinical manufacturing in the Cell Processing Facility (CPF) requires following applicable current Good Manufacturing Practices (cGMP) in a cleanroom processing environment.

SHIFT: TUES - FRI, 7AM-5:30PM (4x10 SCHED)

Responsibilities

• Utilizing aseptic techniques, perform a variety of open cell product manipulations in an ISO 5 biosafety cabinet.
• Follow Standard Operating Procedures (SOPs) and complete required processing documentation such as production batch records.
• Perform cell processing operations such as cell selection/depletion, expansion, stimulation, transduction, cryopreservation, and patient infusion preparation.
• Review executed GMP records for compliance with procedure.
• Identify deviations from approved policies and procedures. Document deviation, investigate occurrence, and contribute to CAPA development.
• Maintain and operate primary process equipment, such as incubators, centrifuges, cell sorting/selection equipment, and controlled-rate freezers.
• Participate in problem-solving and troubleshooting for cell processing operations and equipment. Assist in the evaluation of current practices and operations and help to implement changes to improve performance.
• Contribute to Corrective and Preventative Actions (CAPA) completion, and assist in the execution of change controls.
• Participate in quality/compliance improvement and technical development projects.
• Develop training skills, train junior associates.
• Act as Protocol Champion on existing protocols, assessing materials readiness using a Bill of Materials.
• As Protocol Champion, report production status and production run summary data.
• Assess the need for batch record updates and manage document change requests.

Qualifications

• CPA I: Bachelor's degree in a biological science and a minimum of one year of postgraduate lab experience, or 6 mos+ professional GMP experience. A minimum of four years of related lab experience with high school diploma is acceptable in lieu of bachelor's degree in biological science.
• CPA II: Bachelor's degree in a biological science and a minimum of three years of postgraduate lab experience. 
• Experience with open aseptic processing, working in biosafety cabinets.
• Experience with fundamentals of cell culture. Experience establishing and maintaining long-term T-cell lines/clones preferred. 
• Must be able to work efficiently, with strong attention to detail in a highly regulated environment.
• Proficiency with standard computer programs (MS Office).
• Must be able to support teamwork, and communicate effectively in a diverse team environment.
• Must demonstrate solid time management and organizational skills, and strong verbal and written communication.
• Must be able to wear clean room attire, surgical masks, and all required Personal Protective Equipment (PPE).
• Must have the ability to stand and to work in a biosafety cabinet for long periods.
• Meets physical requirements of the job, as follows: can lift a minimum of 25 pounds and the ability to bend, reach, stretch, and climb ladders.
• Ability to work non-standard shifts and occasional weekend days or evenings. Must be willing to work the Tuesday - Friday, 7AM - 5:30PM shift. 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Lab Technician II/Flow Cytometry Specialist I provides flow cytometry services to Center and external laboratories. The incumbent reports to the Flow Cytometry Director and works independently in performing daily responsibilities according to established procedures.

Responsibilities

• Maintain, calibrate and operate the flow cytometers to meet established performance and safety standards.
• Perform periodic and as needed instrument maintenance.
• Run samples for investigators as requested.
• Instruct investigators in the proper use of equipment, data collection and analysis, providing individual assistance as necessary.
• Provide researchers advice in panel design and experimental troubleshooting.
• Maintain accurate department records including instrument use logs, materials used, supply inventories, capital equipment lists, equipment maintenance lists, department purchases and accounting records.
• Prepare instrument billing for flow cytometry facility use.
• Maintain current knowledge of advances in flow cytometry and recommend improved laboratory equipment as necessary.
• Maintain current knowledge of laboratory data collection and analysis and recommend updated software and equipment as necessary.
• Perform other responsibilities as required.

Qualifications

Required Qualifications:

• Bachelor’s degree in a physical or biological science.
• Experience working with flow cytometry, either as a researcher using instrumentation or in a core facility/service roll.
• Demonstrated skill in working with electronics, equipment and machinery in a lab environment.
• Significant knowledge of laboratory data collection.
• Strong interpersonal and communication skills.

 Preferred Qualifications:

• Molecular and cell biology experience.
• Familiarity with or experience in optical systems, instrument analysis.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.  

Fred Hutch has organized its Cellular and Biological materials process development and GMP manufacturing resources into a Therapeutic Products Program (TPP) wityh a Quality Control and Quality Assurance function. The Quality Assurance department will manage the quality program associated with both GMP facilities and liaise with the Seattle Cancer Care Alliance quality assurance system. The Quality Assurance group is an integral part of the program providing oversight for all manufacturing protocols and managing the FDA relationship. We are seeking a GMP Quality Assurance Manager to provide direct management for our Quality Assurance department while reporting to the Director and Head of TPP Quality.

Responsibilities

• Act as manager for the Quality Assurance Shared Resource within the GMP Therapeutic Products program.
• Manage five -seven full-time Quality Assurance employees providing support to internal investigator protocols as well as external collaborative partners.  
• Establish and ensure appropriate Quality Systems are implemented and maintained, including ongoing data analysis of product and process outputs to ensure early detection and response to quality improvement opportunities and prevention of quality issues
• Ensure compliance with all quality policies and continuous quality improvement initiatives
• Provide expertise and guidance in interpreting governmental regulations, agency guideline and internal policies to ensure site compliance
• Provide coaching and mentorship to the Quality team, ensuring appropriate levels of accountability for quality decisions and clearly communicates cross-functionally within the organization
• Manage all aspects of plant quality systems, including document control, deviations, CAPA, supplier quality, change control, in-process quality assurance, quality control (analytical and microbiology laboratories), finished product review and release
• Hire and manage departmental personnel directly.
• Work with other Quality/Compliance, Operations, Planning, Logistics, Purchasing and Finance managers and personnel to effectively create and support process and quality enhancement initiatives
• Support an aggressive Quality Program, which instills personal accountability for accuracy, consistency and completeness for all operations and departments according to site and corporate policies
• Create and maintain an environment of excellence, world-class quality and continuous improvement throughout the entire plant
• Make fact-based, scientifically sound, quality decisions regarding products manufactured at the facility within the requirements of cGMPs and applicable regulatory/industry guidance documents
• Manage approval or rejection of starting materials, packaging materials, bulk and finished products per the appropriate regulations and site policies and procedures
• Execute and maintain a clear quality vision and strategy for the site
• Supply the highest level of internal and external customer service and measure this through the maintenance and communication of site quality metrics
• Lead and/or support investigations
• Author, approve and/review area quality deviations and investigation reports as appropriate
• Ensure on-time completion of all corrective action items
• Lead the application of appropriate quality technology tools to establish and maintain process capability, and support systems for current pharmaceutical manufacturing
• Work safely in accordance with regulations, standards, and procedures and in a manner that eliminates unreasonable risk to health and the environment

Qualifications

• Bachelor of Science in Chemistry or Biology, Masters degree a plus.
•  6 -10 years of experience within the pharmaceutical or biotechnology industry (preferred) or academic setting.
• 5 years of experience in the manufacturing of Biologics and/or Cell Therapy products
• 5 years in a managerial role managing a team(s) of quality individuals
• Lean/Kaizen/Six Sigma working knowledge preferred
• Experience in working closely with and establishing cross-functional teams for process improvement efforts
• Experience in developing/documenting procedures
• cGMP training experience
• Project management experience
• Expert knowledge of cGMP requirements
• Prior experience in managing inspections performed by FDA and other regulatory authorities.
• Thorough understanding of quality systems
• Complete understanding and application of principles, concepts, practices and standards for testing performed in all QC laboratories
• Expertise in the manufacture and control of finished pharmaceutical products, analytical analysis techniques and statistical quality control
• Strong working knowledge of FDA requirements and guidance documents
• Ability to use relevant software packages to process and analyze data
• Ability to lead an organization during a period of organizational growth and change
• Ability to establish timelines and accountability for Quality and Cross-Functional Team projects
• Excellent written and verbal communication skills

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The Quality Control laboratory performs in-process and release testing in support of Human Gene Therapy Phase I/II clinical research studies. We are looking for a dynamic, skilled, and detail-oriented candidate to join our team. The position will be the subject matter expert for flow cytometry testing activities in our GMP laboratory environment. The position will also be required to perform testing as needed. Cross training in other cell-based potency and microbial assays may eventually be required.

Responsibilities

• Provide technical support and troubleshooting with flow-based characterization and potency assays
• Develop and/or transfer of analytical methods from internal/external partners
• Design or assist in the design of multi-color flow cytometry panels
• Serve as the flow cytometry QC representative in cross-functional teams
• Train and mentor other flow cytometry QC analysts
• Perform in-process, lot release, and stability cGMP testing of raw materials and human gene therapy products
• Perform data review
• Write SOPs and test methods
• Perform deviation and out of specification (OOS) investigations
• Maintain laboratory cell lines
• Maintain equipment
• Perform general activities in accordance to SOPs and laboratory quality systems
   

Qualifications

Required:

• Bachelor’s or master’s degree in a life sciences field with 5+ years (3+ years MS), preferably with a background in biologics and/or cellular therapeutics
• Extensive hands-on experience in the performance of flow cytometry methods to characterize cells using analyzers such as Miltenyi MACSQuant, BD FACSCanto/LSR, Guava easyCyte, etc.
• Familiarity with data analysis software packages such as FlowJo, Miltenyi MACSQuantify, BD FACSDiva, etc.
• Strong communication and writing skills with demonstrated ability to work in a dynamic team environment

Preferred:

• Knowledge of aseptic and cell culture techniques   
• Experience with typical GMP Quality Systems (ex. Document Control, Deviations, CAPA, Change Control, etc.) 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion. 

The Experimental Histopathology laboratory is recruiting a research Histotechnologist to provide routine and customized immunohistochemistry support for Fred Hutchinson research efforts. The incumbent will assist with the design of innovative protocols in a customer service based, team oriented work environment.

Responsibilities

• Perform routine immunohistochemistry on an automated platform and in situ hybridization, routine and special stains, and molecular studies.
• Assist in the vetting of antibodies to be used for specific applications.
• Assist in establishing, optimizing, and customizing histology procedures for fixing, processing, sectioning, staining, and reagent preparation to support immunohistochemistry projects.
• Perform histology according to FDA (Food and Drug Administration) and GLP (Good Laboratory Practices) guidelines and regulations.
• Research, troubleshoot, and test new reagents.
• Optimize antigen retrieval conditions, blocking, detection, and titer to ensure ideal staining conditions for antibodies.
• Work independently as an immunohistochemistry and histology resource for researchers to assist with preparation of their protocols.
• Participate in group meetings with laboratory staff and researchers to discuss experimental design that will meet research goals.
• Accurately log-in, label, organize, and track specimens.
• Maintain inventory and order supplies, as necessary.
• Prepare reagents from detailed laboratory procedures and document that quality control standards are being met.
• Assist in the design and writing of laboratory protocols for all procedures.
• Develop teaching and training materials and teach techniques to technicians, students, fellows, and other scientists.
• Perform routine maintenance on immunohistochemistry, imaging, and other laboratory equipment.
• Assist in organizing work and storage space and in general lab upkeep.
• Perform routine and specialized histology support as needed
• Remain current in the field by completing at least 10 hours of continuing education a year.
• Perform other duties, as assigned.

Qualifications

• The minimum requirement is a bachelor’s degree with 5 years of relevant Histology/Pathology experience including 3 years in IHC. HT or HTL (ASCP) Certification plus one additional certification in immunohistochemistry, molecular pathology, or necropsy or demonstrate mastery of technique.
• The successful technologist must be able to work accurately and efficiently, be detail oriented, and work both independently and within a group.
• Strong troubleshooting and problem solving skills are required.
• This position requires excellent written and verbal communication skills and the ability to work positively in a customer oriented environment. In addition, the incumbent must be flexible and skilled at organizing and prioritizing tasks.
• Familiarity with Microsoft Word, Excel, SharePoint, and Internet Explorer is desirable.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

This position is in a service laboratory within the Research Cell Bank in Shared Resources. The laboratory provides cell banking services to researchers at Fred Hutch and around the world.

The technician will be responsible for the processing of human blood samples, including isolation, purification, and cryopreservation of lymphocytes and the transformation, expansion, and cryopreservation of B-lymphoblastoid cell lines. Candidates should be familiar with the use of molecular biology techniques such as DNA extraction, PCR, and DNA typing. Responsibilities will also include the performance of quality control procedures for tissue culture and DNA, the recording of data and maintenance of a laboratory database, and participation in the prioritization of laboratory activities. The position may involve work on some weekends and/or evenings.

This position will have a Tuesday – Saturday schedule.

Qualifications

• Bachelor’s degree in a biological field is required
• At least one-year experience in a biotechnology type lab is strongly preferred
• At least 3-6 months of tissue culture or clinical sample processing (blood) experience is required
• Experience with standard molecular biology techniques, and DNA quantification and purification are required
• Motivation and willingness to work with blood samples and a large number of cultured cell lines
• Organizational skills and the ability to take detailed and accurate laboratory notes are essential
• Ability to multi-task with precise attention to detail is especially critical
• Must be able to work under pressure in a highly dynamic environment where priorities can shift without advance warning
• Experience using computer application software, including Microsoft Excel and PowerPoint is required
• The ability and desire to work cooperatively with others in a team environment
• Flexibility regarding the work schedule

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The Fred Hutch Antibody Technology Resource is nationally recognized for its novel monoclonal antibody discovery platform. The facility supports Fred Hutch research labs across all five divisions, generating antibodies for basic science needs as well as clinical diagnostic and therapeutic applications. Other clients include regional academic research institutes and biotech companies. The lab has been completely updated over the past five years with cutting-edge instrumentation for antibody discovery including: Molecular Devices ClonePixII colony picker, IntelliCyt iQue Screener, AKTA Pure FPLC, Protein Simple WES capillary electrophoresis, Carterra and a $1.2M robot which automates significant parts of the antibody discovery process.

Responsibilities

Our group is seeking a Research Technician IV who will work with the resource Director to run antibody discovery projects from initial design and immunization to monoclonal antibody purification and kinetic determination.  The successful candidate must have a desire to learn new skills in order to complete all stages of this multidisciplinary process. The candidate will contribute to the team’s knowledge base through their expertise. This is a fast-passed, team-centric work environment which requires independence, organization, and time management skills. Specific responsibilities include:

• Engineering both antibodies and antigens, ideally including humanization.
• Running kinetic/binning experiments on antibodies using a Carterra Surface Plasmon Resonance (SPR) instrument
• Sequencing, cloning, expressing and purifying antibodies
• Screening antibodies using robotics and flow cytometry
• Generating hybridomas and/or culture B cells
• Immunizing animals
• Working with director to design antibody discovery campaigns

Qualifications

The successful candidate must be highly motivated, reliable, and independently productive.  Specific qualifications include:

• BA/BS or MS degree in a scientific discipline with 5-15 years hands-on laboratory experience
• A proven ability to engineer proteins including antibodies
• Excellent molecular biology skills (PCR, cloning, transient transfection)
• An ability to transfect cells, ideally this would include through lentivirus
• An understanding of High Performance Liquid Chromatography and significant experience running an AKTA
• An understanding of protein kinetics and use of SPR instruments
• A willingness to learn how to perform screening, generate hybridoma and use robotics

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Fred Hutch is seeking a Senior Director, Clinical Manufacturing and Resources. This program includes GMP manufacturing of clinical grade cellular and biological products and resources supporting a wide variety of clinical trials.  Clinical manufacturing includes Cell Processing, Biologics Production, Quality Assurance, Quality Control, and Process Development.  Clinical Resources include Immune Monitoring and Specimen Processing. The Senior Director will manage operations and ensure the success of these critical clinical research resources. 

Responsibilities

The Sr. Director will have operational/financial oversight of seven core resources, including Cell Processing Facility, Biologics Production Facility, Quality Assurance, Quality Control, Process Development, Immune Monitoring and Specimen Processing.  The Sr. Director will be responsible for the efficient production and quality of both research and clinical-grade cellular and biological products and appropriate processing of clinical samples to serve and anticipate customer needs.  The Sr. Director reports to the Vice President, Interdisciplinary Science Administration.

Specific responsibilities include:

Leadership

• Responsible for performance and support of five resource Directors. The Sr. Director will promote continuous development of a team of manufacturing and quality professionals. 
• Lead strategic planning and develop and optimize plans for staffing, plant operations, and finance that support strategic goals and ensure compliance with FDA and GMP regulations.
• The Director will report to faculty advisory committees on a recurring basis concerning current operations, finance, and future needs and plans for the facility.

Financial management and Business Development

• Responsible for operating and capital budgets in collaboration with central Shared Resources administration
• Develop and maintain appropriate rate structures, conduct yearly reviews of rates, and ensure timely and appropriate billing in all resources.
• Assess new program opportunities and ensure robust support and collaboration with external and alliance partners.

Operations

• Develop and implement the overall strategy, priorities, and quality vision. Responsible for management of physical plant, operations, and data systems.
• Ensure coordination of production scheduling, project planning and quality program structure in collaboration with the core Directors.
• Assess needs and potential to expand services in response to end user needs.
• Ensure appropriate Quality Systems are maintained, including ongoing data analysis of product and process outputs to ensure early detection of quality issues and response to quality improvement opportunities.

Customer Service

• Collaborate with all users of clinical resources to ensure the highest possible quality in the facility, assess needs for operational changes, and anticipate and plan for future operational requirements.

Qualifications

• A Bachelor’s Degree (Master’s Degree or PhD preferred) with at least 5 years of experience in GMP manufacturing in a senior management role. 

• The candidate will have at least 5 years professional experience managing senior level personnel.  Strong leadership skills are required to lead clinical resources through periods of growth, change and time pressure. The ideal candidate will have a demonstrated ability to:

  • effectively lead individual teams as well as act collaboratively across an organization;

  • establish timelines, benchmark accountability and oversee program and project budgets;

  • develop and document procedures through strong project management skills and excellent written and verbal communication skills;

  • analyze data and apply an analytical framework to decision making.

• A high level of knowledge of cGMP and FDA requirements and guidance documents and a thorough understanding of quality systems is preferred, as is prior experience in managing inspections performed by the FDA and other regulatory authorities.
• Experience in the manufacturing of Cellular Therapeutic or Biological products is preferred. 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Comparative Medicine Transporter Technician position assumes responsibility for transporting materials, people, and animals between various local locations as well as completing small and large animal husbandry duties, custodial care, supply distribution, and inventory duties for the department. This position is under supervision of the Animal Facility Managers. Knowledge of and adherence to department procedures and animal handling guidelines are essential.

The Transporter Technician is classified as essential personnel and, as such, is required to work with minimal amount of absences and during all Center closures except in the event of a major disaster when access to animal housing and use facilities is prohibited by governmental emergency personnel.

Responsibilities

PRIMARY JOB DUTIES

• Drive animals, personnel, equipment and supplies to and from Fred Hutch locations to other local locations (e.g. vivariums, storage, airport or other local facilities) to maximize operational efficiencies and effective use of care days. Maintain an understanding of differing destination site requirements and regulations.
• Promote interdepartmental communication and collaboration to ensure timely and accurate movement of animals between locations. Learn and develop familiarity with electronic communication systems used to schedule transport.
• Coordinate and collaborate with facility management and research staff to identify animals for transport. Help prepare animals for transport including but not limited to removal/return to appropriate cages and/or holding racks.
• Ensure paperwork accompanying animals on transport is complete and compliant with internal and external transport requirements.
• Coordinate vehicle availability and maintenance needs.
• Assist as necessary in transport and receipt of animals from external vendor sources.
• Learn to and become proficient in Personnel Protective Equipment policies and procedures throughout the animal facilities
• Maintain an understanding of effective and safe animal handling and disease management principles. Demonstrate safe and appropriate animal handling.
• Learn to and become proficient in effectively communicating with research staff through verbal, written, or electronic means. 

SECONDARY JOB DUTIES

• Provide care for all small animal species in accordance with standard operating procedures, providing feed and fresh water to animals and changing animal housing when necessary.
• Learn to evaluate animals’ general health, report abnormalities to the small animal veterinary technicians or veterinarian for veterinary evaluation. Learn to perform preventive animal health care duties and administer treatments as prescribed.
• Provide care for canines in accordance with standard operating procedures including cleaning and sanitizing canine enclosures, feeding animals (standardized and prescribed diets), assuring that animals have fresh water at all times, transferring animals to clean caging, performing complete housekeeping duties in animal housing areas and surrounding premises, performing laundry cleaning services, and bathing, and socializing of the canines.
• Preform housekeeping duties such as sweeping, mopping, garbage removal, and equipment washing in animal housing areas and surrounding premises.
• Maintain accurate records of animal identification, veterinary treatments, animal census, facility housekeeping, and room parameters (e.g. daily temperature high and low).
• Learn to and become proficient in appropriately mixing and use of all cleaning solutions according to established SOPs and/or manufacturers’ instructions.
• Learn to and become proficient in material management inventory control, notifying the supervisor or designated technicians of items that need to be ordered.
• Attend and participate in assigned training classes, and become familiar with, and learn to utilize web based DVMax and eSirius systems for record keeping and other uses.
• Work on call, weekend, evening, or holiday shifts as needed or as assigned.
• Perform other duties as assigned.

Qualifications

• High school diploma or equivalent
• Maintenance of a valid Washington State Driver’s License and good driving record
• Good verbal and written communication skills
• Ability to follow written and verbal instructions that are presented in English
• Ability to lift and move 50 lbs on a regular basis and sustained physical activities such as bending, balancing, stooping, reaching, and remain standing for long periods of time
• Ability to wear Personal Protective Equipment including scrubs, disposable coveralls, gloves, shoe covers, gowns, ear plugs / muffs, face mask, and eye protection
• Science and animal husbandry background including prior experience or education in animal care preferred

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Veterinary Technician provides support to veterinary staff and Center laboratories by performing a variety of technical procedures and health assessments in studies involving laboratory animals. Completion of these tasks will be expected to be conducted independently without direct supervision. A clear understanding of research protocols is required for work on animal manipulation segments of the protocols. This position reports directly to the Veterinary Technician Manager.

The Veterinary Technician is classified as essential personnel and, as such, is required to work with a minimal amount of absences and during all Center closures except in the event of a major disaster when access to animal housing and use facilities is prohibited by governmental emergency personnel.

Responsibilities

The Veterinary Technician works independently to provide veterinary care to research animals as well as performing specialized job assignments related to facility and research support. The Veterinary Technician is expected to rotate between any of the animal facilities when requested. The primary responsibility of this position is providing veterinary care for research animals under direction of the Veterinary Technician Manager and Clinical Veterinarians. Other responsibilities range from providing technical services for research support, assistance in the health monitoring program, training to operate specialized equipment, and assisting in other aspects of animal care. The position requires a basic understanding of animal anatomy, anesthesia, euthanasia, veterinary supportive care, biohazard containment, chemical hazard containment, radiation hazard containment and risk-reduction measures. Knowledge of the investigators’ needs with respect to the scientific process, the content of the corresponding IACUC approved protocols, the animal welfare regulations and the assurance of animal health and well-being are required.

• Provides appropriate veterinary care to animals housed in Fred Hutch animal facilities under direction of the Veterinary Technician Manager. To include assessment, treatment plan, communication with research and husbandry staff, and Clinical Veterinarians. This includes preventative animal health care duties.
• Maintains appropriate animal health records. Requires proficiency in Microsoft Office and use of the DVMax, eSirius, and Hutch IACUC systems for record keeping and referencing project information.
• May provide trainings to researchers or other CM staff, to include facility orientation as well as hands-on training and instruction for routine technical skills involving animal care and research activities.    
• May perform routine study related activities such as subcutaneous, intradermal, intravenous, intraperitoneal, intramuscular, and other injections. Monitors animal’s subsequent wellbeing, and provides supportive care, under the direction of veterinarians, as appropriate.
• Performs or assists other veterinary staff with exams, drug treatments, wound treatments, bandage changes, ear cleaning, fecal sampling, blood sampling, injections, animal weights, care of neonates, transport, placing of catheters, administering IV fluids, dental care, laboratory procedures (fecals, vaginal cytology, urinalysis, complete blood counts), bone marrow aspirates, instrument care and identification, emergency procedures and other critical care.
• May perform necropsies and harvests of biological specimens for scientific study, veterinary assessments, or health monitoring program. May include blood, urine, bone marrow, skin, tail biopsies, and solid organ harvests.
• Must be well-versed in laboratory rodent and large animal housing, radiation safety, biohazard containment, and biosecurity for known or potential infectious diseases. Trained to implement risk reduction measures as they pertain to facility activities.
• Administers general anesthesia, performs patient monitoring, and may assist with surgery for major operative procedures in animals, using appropriate aseptic techniques. Provides follow-up care as directed by veterinarians.
• Inspects newly arrived animals for general health and reports abnormalities to the Veterinary Technician Manager or Clinical Veterinarians. May assist in the preparation of animal housing appropriate for the species.
• May be responsible for breeding, weaning and identification of animals and maintenance of colony records.  
• Appropriately identifies animals per established SOPs, maintains accurate records of animal identification, daily room tallies, and labor allocation.
• Performs animal care and custodial duties (feeding, watering, cleaning, laundry) when necessary.
• Participates in material management inventory control and request purchase requisitions as necessary. Summarizes and submits appropriate documentation to ensure cost-recovery for services rendered.
• Helps supervisors and veterinarians ensure that areas within the facility meet institutional and federal regulatory standards and compliance with CM guidelines and SOPs.
• Appropriately uses, documents use, and assures security of controlled substances.
• May transport animals supplies or equipment between facilities and institutions. Assists veterinarians with planning and record-keeping for animal shipments.
• Operates cage washing equipment including mechanical rack, autoclave, pressure washer and other cleaning equipment and devices and performs environmental control tests to validate and ensure proper function and document test results.
• Takes all training and fulfill regulatory requirements to operate LINAC, gamma irradiators, or other specialized equipment, and becomes proficient in the operation of the LINAC and other equipment as required.
• Implements environmental enrichment and social housing requirements for USDA-covered species according to CM and IACUC policies and guidelines and assures compliance with these guidelines for non-USDA species.
• Assumes Veterinary Technician Lead responsibilities on a short-term basis if requested.
• Participates in assigned required training and other formal continuing education appropriate for professional growth and service excellence in these responsibilities. Licensor for LVT, membership in the local AALAS branch, and AALAS technician certifications are encouraged and supported by CM.
• Works on call, weekend, evening, or holiday shifts as needed or assigned.
• Performs other duties as assigned.

Qualifications

MINIMUM QUALIFICATIONS:

• A bachelor’s degree in a biological science or Associates Degree in Veterinary Technology.
• Ability to read and write clearly and follow instructions precisely.  
• Prior experience, training or education in laboratory animal care and in a variety of veterinary technical procedures is desired (typically in excess of one year).
• Basic understanding of the scientific process, including aspects of study design with experimental and control groups and in appropriate methods and levels of documentation is also required.
• Knowledge of the IACUC oversight process, including methods to assure animal well-being through animal care.
• Use protocols via the Comp. Med veterinary care program is essential.
• Perform procedures that may require lifting up to 50 lbs. This may include lifting animals, feed, bedding, equipment and/or supplies.
• Ability to wear Personal Protection Equipment may include scrubs, disposable coveralls, gloves, shoe covers, gowns, ear plugs / muffs, face mask, and eye protection. 

PREFERRED QUALIFICATIONS:

• AALAS certification at the LATg level is recommended, and persons hired for this position should continue to pursue this certification as soon as possible once eligible until achieved.
• Maintenance of state license (LVT) is preferred.
• Maintenance of a valid Washington State Driver’s License and good driving record.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.