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48 Found open positions

Administrative Manager I

FH Vaccine and Infectious Disease Division
Category: Administrative Support
Seattle, WA, US
Job ID: 19074

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking an Administrative Manager I to join their Administrative Services team. The Administrative Manager is responsible for the planning, coordination, and implementation of administrative functions of SCHARP with a focus on supporting the human resource, technology and general day-to-day needs of staff, and overall business operations.  

Responsibilities

Human Resources

  • Partner with SCHARP managers, Fred Hutch HR and Center CIT teams on the process of recruiting, hiring, onboarding and offboarding new or departing staff
  • Conduct orientations for new staff and affiliates
  • Maintain all materials, process documents and trainings related to hiring, orientation, retention and termination of staff
  • Maintain HR staffing data, reports and job descriptions

 

Technology & Facilities

  • Serve as the primary liaison with Center IT related to service issues, escalate and resolve staff technology challenges
  • Responsible for managing the budgeting, purchasing and inventory of large office equipment, such as laptops, monitors, office furniture, etc.
  • Track and maintain data on workspace inventory

 

Program Support:

  • Respond to requests and manage special projects, activities and events
  • Support Quality audits through monthly reports, reviews of administrative data and information
  • Maintain SCHARP and Admin SharePoint pages
  • Participate in meetings including, VIDD Administrative Management, BBE Program Operations and SCHARP Executive Management Group
  • Backup and collaborate with other administrative staff to support the business needs of SCHARP
  • Other responsibilities as assigned

Qualifications

Minimum qualifications

  • BA/BS in related field and 3+ years OR equivalent combination of education/experience will substitute for minimum qualifications
  • Excellent written and verbal communication skills
  • Advanced knowledge of Microsoft Outlook, Microsoft Word, Excel and PowerPoint
  • Experience with the budget process and/or developing financial reports
  • Exceptional organizational skills and attention to detail
  • High degree of professionalism, integrity and outstanding interpersonal skills
  • Comfortable working in a fast-paced, constantly changing, matrixed environment

 

Preferred qualifications

  • MA/MS desired
  • Experience in a research or academic setting
  • Experience using SharePoint, Teams, Slack and web conferencing platforms
  • Knowledge or spirit of inquiry for continuous performance improvement
  • Demonstrated ability to work independently and as part of a team
  • Ability to effectively partner with teams and individuals with diverse skill sets
  • Positive attitude and sense of humor


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Associate Director of Vaccine Immunology Statistical Center (VISC) Operations

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
US-WA-
Job ID: 18985

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The Gottardo Lab is looking for an Associate Director of Vaccine Immunology Statistical Center (VISC) Operations.

 

Led by Dr. Raphael Gottardo, the VISC partners with world-class research programs to tackle global public health initiatives in infectious disease. The VISC operates within two global research networks: the Collaboration for AIDS Vaccine Discovery (CAVD) and the Global Health Vaccine Accelerator Platforms (GH-VAP). The VISC has additional dedication to open science exemplified by their DataSpace web application.

 

The CAVD is an international network of scientists and experts dedicated to designing a variety of novel HIV vaccine candidates and advancing the most promising candidates to clinical trials.  The GH-VAP supports laboratory and clinical research to accelerate vaccine discovery and translation related to non-HIV infectious diseases, including COVID-19, TB, and malaria.


The Associate Director of VISC Operations oversees operations for the VISC and related projects and reports directly to the VISC principal investigator (PI).  The Associate Director provides day-to-day management of the work, is responsible for relationship management among internal and external stakeholders, and serves as the PI’s representative when needed.

 

The Associate Director will be a member of the VISC Leadership Team and will significantly contribute to the formulation and implementation of strategic decisions of the network.  The Associate Director is expected to establish and maintain strong, positive, and productive relationships among Biostatistics, Bioinformatics and Epidemiology (BBE) faculty, Statistical Center for HIV/AIDS Research and Prevention (SCHARP) leadership and staff, external partners, and the sponsor.  The Associate Director will provide fiscal oversight and make day-to-day management decisions regarding the work supported by the VISC.  The Associate Director will also be responsible for direct management of a junior project manager and will provide guidance and mentorship for SCHARP staff.

Responsibilities

  • Provide leadership, strategic planning, fiscal oversight, and make management decisions for the work supported by the VISC and related grants
  • Serve as an active member on the VISC Leadership Team along with the PI, and other objective leads
  • Represent the VISC at internal and external meetings as needed
  • Participate in meetings and discussions with other Strategic Alliance members and represent VISC and its interests
  • Manage existing relationships with key stakeholders and establish working relationships with new collaborators and partners
  • Engage and support faculty charging to the VISC grant.  Establish ongoing relationships with faculty and ensure there is open communication about resources and general awareness between the faculty and the PI of work being supported by the grant.
  • Collaborate with SCHARP functional managers to assign and prioritize work to match with network strategic goals
  • Oversee relationships with contractors and vendors providing services to the VISC. Ensure work is completed on time and within allowed budgets.
  • Performs all management tasks, to include hiring, training, workload prioritization and allocation, discipline, termination, and evaluation of direct reports
  • Provide guidance and mentorship to junior project managers and other SCHARP staff
  • Defines and manages scope of work, timelines, and resources associated with new projects, or deliverables
  • Oversee budgets. Review budgets and effort allocation monthly with the VIDD Finance Department to ensure that effort matches appropriately with the work being done. Investigate unexpected charges and escalate/engage with others as appropriate. 
  • Contribute to preparation of grant applications and annual progress reports, providing guidance to the VIDD Finance Department for budgeting purposes and contributing scientific descriptions of how the aims of the grant were or will be implemented
  • Lead or participate in SCHARP committees and working groups
  • Perform other duties as required

Qualifications

  • Bachelor's degree in statistics, immunology or vaccine/laboratory-research related field; Master's or PhD preferred
  • Minimum of five years of management experience with demonstrated progressively increasing scope of responsibilities
  • Experience working with complex groups within a research and laboratory research environment
  • Strong leadership, to include communication, organization, negotiation, and interpersonal skills expected, coupled with proven ability to manage competing priorities and timelines
  • Strong written and verbal communication and management skills
  • Demonstrated ability to build successful working relationships with relevant collaborators
  • Resource and personnel management, budget oversight, and grant writing desired

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Bioinformatics Analyst

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18939

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


 

The HIV Vaccine Trials Network (HVTN) is the world’s largest publicly funded multi-disciplinary international collaboration facilitating the development of vaccines to prevent HIV/AIDS, through clinical research studies. Most recently, the COVID-19 Prevention Network (CoVPN) was formed by the National Institute of Allergy and Infectious Diseases (NIAID) at the US National Institutes of Health to respond to the global pandemic. Using the infectious disease expertise of their existing research networks and global partners, NIAID has directed the HVTN to utilize their experience and expertise to address the pressing need for vaccines and antibodies against the SARS-CoV-2 virus. The mission of CoVPN is to conduct Phase 3 efficacy trials of vaccines and antibodies to prevent infection and COVID-19 disease, to ensure rapid and thorough evaluation that can support approval and dissemination of the interventions. 

 
The Bioinformatics Analyst will provide analytical and programming support as part of the Bioinformatics Core and Biosequence Analysis Unit of the HIV Vaccine Trials Network and Coronavirus Prevention Network.  The field of vaccine research is increasingly relying on the use of high-throughput genetic and proteomics data to make scientific advancements, and the HVTN and CoVPN are looking for a person with the skills, drive and curiosity to help us overcome these epidemics.

 
This position has responsibilities for both data analysis and programming support for our data and information infrastructure.  This is an applied position, where computer programming and data analytics are toolkits for solving scientific problems, typically involving viral sequence data integrated with clinical and immunology data.  The ideal candidate will have a grounded understanding of statistics/data analysis, and software development – especially high-performance computing – as well as a deep scientific curiosity about applying software and data analysis to the field of vaccine research.

Responsibilities

  • Work with scientific and analytic collaborators to define analysis and data requirements
  • Manage and process multifarious types of study data
  • Developing software processes and pipelines for data management, data processing and analysis
  • Generating data visualizations and reports of analysis results
  • Software development for long-term data-management, analysis, and infrastructure projects
  • Presenting scientific results and contributing to scientific papers
  • Work collaboratively with both our local team and a global network of scientists
  • Perform other responsibilities as required

Qualifications

Minimum qualifications

  • Bachelor’s degree in the quantitative or physical sciences, or equivalent experience
  • 2-4 years of experience with scientific computing, ideally in the domain of biomedical/scientific research and genomics/proteomics
  • 2+ years of experience programming in R and/or Python, ideally both
  • 2+ years of experience with high-performance computing (i.e., the development of multi-core or multi-threaded computational jobs)
  • Strong analytical abilities and problem-solving skills
  • Experience in data management and developing data-processing pipelines
  • Knowledge of databases, including relational databases and no-SQL databases, e.g., MongoDB
  • A solid understanding of high-level programming concepts, data structures and algorithms
  • Familiarity with inferential statistics and machine learning
  • Familiarity with software development best practices (e.g., unit testing, version control)
  • Excellent written and oral communication skills

 

Preferred qualifications

  • Master’s degree or greater in the quantitative or physical sciences
  • Competency in other programming languages, such as Java and/or C++
  • 2-4 years experience working with genetic/proteomic data, ideally in the field of pathogen genomics
  • Experience working with lab assay data
  • Experience working with reproducible research tools and processes
  • Experience with containerization (especially Docker) and virtual machines
  • Proficiency in working with and developing software in Linux-based operating systems

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Bioinformatics Analyst I-II, Computational Analyses of Microbial Genomic/Metagenomic/Epigenomic Data

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18060

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


 

The Johnston Laboratory in the Vaccine and Infectious Disease Division at the Fred Hutchinson Cancer Research Center is recruiting a highly motivated and creative Bioinformatics Analyst to analyze multiple unique data sets primarily associated with long-read sequencing technologies (PacBio) including large scale computational genomics of microbial genomes, patient tumor and tissue metagenomics, and microbial/eukaryote epigenetics.

 

The Johnston Laboratory is an interdisciplinary and highly collaborative team of classically trained microbiologists, synthetic microbiologists, bioinformaticians and engineers. Using cutting edge technologies and methodologies, we seek to gain a deeper functional understanding of what bacteria are doing and how they are doing it. We then use that information to create novel therapeutics and engineer the next generation of microbe-based technologies for application in human medicine, synthetic microbiology and bioengineering.

Responsibilities

The Bioinformatics Analyst will be responsible for working with our team to provide data analyses and visualizations of primarily microbial datasets (Genomic/Metagenomic/Epigenomic data). A successful candidate will have experience in data analysis, generating visualizations, writing analyses summaries and abstracts, and managing time across various projects with different collaborators. Responsibilities and essential job functions include but are not limited to the following:

  • Supports the maintenance of computational infrastructure and the flow of samples and information for large-scale studies.
  • Contributes to web-based bioinformatics and public and proprietary relational databases. Assists in the development and application of computational tools.
  • Interpret complex biological information, conduct statistical and genomic analysis.
  • Write custom scripts to access databases, perform and evaluate quality control and analyze Next Generation Sequencing (NGS) data.
  • Assist in the development and refinement of data analysis and integration methodology and pipelines.
  • Develop modular and reusable software for use in basic science research and genomic analysis in a cost-effective and efficient manner with limited instruction or guidance.
  • Engage in bioinformatics literature to ensure the availability of robust methods, resources, and data sources. Work with research collaborators to gather requirements and create processes and pipelines to meet their research goals
  • Candidate must demonstrate outstanding personal initiative and creativity in problem solving
  • Excellent written and oral communication skills are required for manuscripts/grants preparation, public presentation, and collaboration with other researchers

Qualifications

The successful candidate will be involved in multiple funded projects and work closely with bench scientists during project design, method development, and data acquisition; executing, improving, and developing informatics pipelines based on evaluation of computational tools and reference databases; and conducting and reporting data analysis using principles of good statistical scientific practice and reproducible research.

 

We are accepting applications for either a Bioinformatics Analyst Level I (min 0-2 years) or Level II (min 3-6 years).

 

Minimum Qualifications:

  • Bioinformatics Analyst I Education: BS degree in Biology, Statistics, Computer Science or equivalent education with 0-2 years of work experience with bioinformatics in relevant scientific domain
  • Bioinformatics Analyst II Education: BS degree in Biology, Statistics, Computer Science or equivalent education with 3-6 years of work experience with bioinformatics in relevant scientific domain
  • 2+ years of experience in software development, data engineering, data science, or related field with a track record of manipulating, processing, and extracting value from large datasets
  • Extensive experience working with at least one of the following datasets, e.g. whole genome analyses (assembly and annotation tools, Pangenomics), Metagenome analyses (community compositional assessment and comparisons), epigenome analysis (SMRTseq, ChipSeq, ATACseq - data pipelines)
  • Proficiency in, at least, one modern scripting or programming language (Python, R, Node, or C++)
  • Ability to learn new tools and content quickly and independently
  • Strong oral and communication skills


Desired Qualifications:

  • MS degree with 2+ years of work experience with bioinformatics in relevant scientific domain
  • Beneficial experience relative to this role:
  • Experience with workflow solutions (e.g. NextFlow, Airflow, Luigi, Cromwell)
  • Experience using source code management and CI/CD solutions (e.g., Git, GitHub, Jenkins, GitLabCI)
  • Experience with AWS services (e.g. EC2, S3, Batch, Lambda)
  • Experience with application container solutions (e.g. Docker, Singularity)

 

Application Instructions:

Applications will be considered commensurate with experience and track record of achievement. Please include a cover letter with your application, detailing your interest and suitability for this position.

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Bioinformatics Analyst II

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18853

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.  

 


 

The Gottardo Lab at Fred Hutch is a research lab within the computational biology program focused on creating statistical methods and software tools to analyze high throughput biological data. In collaboration with bench scientists and clinicians we work to understand severe diseases such HIV, malaria, and cancer and ultimately help develop vaccines and/or a cure. You can learn more about the lab and lab members at http://rglab.org/

 

The Bioinformatics Analyst is responsible for working with our collaborators to provide data analyses and visualizations using our bioinformatics tools. The bioinformatics analyst position will work with a small team of bioinformatics specialists and developers to achieve our goal of using computational methods to understand complex diseases. A successful candidate will have experience in data cleaning, data analysis, generating visualizations, writing analyses summaries and abstracts, and managing time across various projects with different collaborators.

Responsibilities

Responsibilities and essential job functions include but are not limited to the following:

  • Work with research collaborators to gather requirements and create software processes and data analysis pipelines to meet their research goals
  • Provide statistical analysis, data summaries, and visualizations for use in collaborating projects
  • Participate in meetings and presentations with collaborating labs
  • Write abstracts and summaries around computational methods
  • Assist team with data management tasks such as data cleaning and data standardization

Qualifications

Minimum:

  • BS degree in Biology, Statistics, Computer Science or related
  • 3+ years of experience in software development, data engineering, data science, or related field with a track record of manipulating, processing, and extracting value from large datasets
  • Some professional experience cleaning and analyzing biological assay data, e.g. flow cytometry, CytOF, single-cell genomics
  • Proficiency in a modern programming language used in data science (e.g. R, Python, SAS, Matlab, Scala, Java, C++)
  • Ability to learn new tools and content quickly and independently
  • Strong oral and communication skills

 

Preferred:

  • Experience using source code management and CI/CD solutions (e.g., Git, GitHub, Jenkins, GitLabCI)
  • Experience doing reproducible analysis using tools like Rmarkdown or Jupyter notebooks
  • Experience with application container solutions (e.g. Docker, Singularity)
  • Experience with AWS services (e.g. EC2, S3, Batch, Lambda)
  • Experience with workflow solutions (e.g. NextFlow, Airflow, Luigi, Cromwell)

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Biostatistician III-IV

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 19026

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


 

The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking a Statistical Research Associate level III-IV.

Responsibilities

The Statistical Research Associate provides low advanced-level statistical support in the planning, operations, monitoring, analytic, and exploratory stages of clinical trials and research. Job duties may include some or all of the following:

  • Collaborate with PhD statisticians/epidemiologists, SRAs, laboratory scientists, laboratory data managers, and other subject-matter experts to provide statistical support for clinical studies and research projects or laboratory data and analyses including statistical considerations and planning (power and sample size calculations), randomization lists, consultation, study data analyses, and written summaries and tables of results for use in study reports - for example, Data and Safety Monitoring Boards or other interim review meetings, scientific abstracts and manuscripts, and/or tables in support of a Clinical Study Report for submission
  • Contribute to and review study documents including protocol drafts, statistical analysis plans, case report forms, and other documents as required
  • Collaborate with data management and operations in the development of quality assurance procedures for on-going data collection, cleaning and analysis - such as establishing edit checks, or HIV endpoint verification
  • Participate in verification of standard reports prepared by programmers or other team members
  • Apply and adhere to CDISC data standards and guidelines where required in the production of analysis datasets and reports; assist in the production of supporting CDISC documentation for submissions (Define.xml, Reviewer’s Guides)
  • Generate written summaries for use in customized statistical lab reports
  • Participate in protocol team conference calls and meetings, organizational meetings, interim data review meetings, scientific meetings, regional meetings and internal team meetings as required
  • Maintain functional understanding of standard policies and procedures and complete required training in a timely manner; Contribute to the development and maintenance of standard procedures and related quality documents
  • Participate in internal project initiatives which may include developing new tools and processes, evaluating new statistical software packages, or exploring other value-added team activities
  • Represent SCHARP and the data analytics unit at professional meetings
  • Mentor or formally supervise more junior SRAs as required. Conduct performance reviews of direct reports
  • Perform other responsibilities as required

Qualifications

Minimum qualifications:

 

Level III

  • MS or PhD degree in Statistics or Biostatistics or related field with demonstrated work experience
  • A minimum of 3 years of related work experience is required
  • Proficiency with the SAS or R (as required by specific team/project)
  • Demonstrated knowledge of general statistical practice within clinical trials
  • Thorough understanding of statistical programming process and best practices
  • Functional understanding of GCP and regulatory requirements
  • Proven track record of collaboration with internal colleagues
  • Strong oral and written communication skills

 

Level IV

  • MS or PhD degree in Statistics or Biostatistics or related field with demonstrated work experience
  • A minimum of 4 years of related work experience is required
  • High-level proficiency with the SAS or R (as required by specific team/project)
  • Demonstrated functional knowledge of general statistical practice within clinical trials
  • Thorough understanding of statistical programming process and best practices
  • Minimum of 1 year of experience in a senior, lead or management role
  • Minimum of 1 year of experience statistical project management
  • Strong oral and written communication skills
  • Strong organizational and multi-tasking skills
  • Functional understanding of GCP and regulatory requirements
  • Proven track record of collaboration with internal and external partners


Preferred qualifications:

 

Level III

  • 4+ years of relevant work experience
  • Demonstrated specialized knowledge of statistical practice within network specialization
  • Proven track record of collaboration with external collaborators

 

Level IV

  • 5+ years of relevant work experience
  • Demonstrated specialized knowledge of statistical practice within network specialization
  • Proven track record of collaboration with external collaborators
  • 2+ years of experience in a senior, lead or management role
  • 2+ years of experience in statistical project management
  • Functional understanding of network needs and objectives
  • Able to lead network-specific statistical tasks with minimal supervision


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Business Analyst II

FH Vaccine and Infectious Disease Division
Category: Project Management
Seattle, WA, US
Job ID: 18711

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking a Business Analyst to translate and document the business needs of SCHARP into process improvement and solution engineering requirements by leveraging both their knowledge of process as well as business analysis best practices within a system development life cycle.

Responsibilities

  • Work closely with SCHARP’s network partners and end users to author business requirements, use cases, functional specifications and internal client communications documentation
  • Convert customer / business needs into product requirements
  • Collaborate on complex projects, facilitate and conduct business and functional requirements gathering workshops
  • Recommend solutions to meet changing business needs
  • Build detailed knowledge of business processes across functional areas
  • Use standard methodology to document business processes
  • Perform business process analysis
  • Map both simple and complex business processes (AS-IS & TO-BE) and/or larger scope workflow
  • Lead the development of future recommendations and conduct presentations to stakeholders
  • Create end user test cases for use by user acceptance testing participants
  • Organize and manage user acceptance testing (UAT)
  • Support the defect evaluation and prioritization process
  • Play the role of Product Owner for assigned applications as part of the system development life cycle
  • Maintain product backlogs and facilitate prioritization for applications assigned
  • Participate in software selection based on documented business requirements
  • Participate in analysis and recommendation of software solutions based on business requirements

Qualifications

Minimum qualifications

  • Bachelor's degree in business administration, computer science, or information management systems; or 5-years of related experience
  • At least 3-years of professional experience as a business or systems analyst or functionally equivalent position
  • Ability to gather and document business requirements and convey to internal stakeholders
  • Ability to gather and document functional requirements and convert to production specifications
  • Ability to communicate free of technical language to the business and end-user
  • Demonstrated expertise in analytical thinking and problem solving
  • Strong collaboration, multi-tasking, and organization skills
  • Strong oral and written communication skills
  • Ability to work independently or on project teams and balance multiple priorities
  • Demonstrated knowledge of business analysis best practices
  • Demonstrated knowledge of agile system development life cycle


Preferred qualifications

  • CAPM or CCBA
  • Experience working in or understanding of clinical research data management or data analytics systems and workflows
  • Experience working in a regulated environment
  • Demonstrated knowledge of UML, specifically for use cases and diagrams


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Clinical Data Manager II-III

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 19151

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. 

 

SCHARP is seeking a Clinical Data Manager (CDM) to join their group. The CDM leads and monitors the collection, processing, data entry and quality control of study data. They are responsible for effectively managing timelines, quality and delivery of data for assigned projects that are in support of clinical trials research. They develop and maintain successful working relationships with their team and specific research sites to ensure and maintain data integrity and quality. The CDM works within a network/study/protocol team to support the policies and goals of each project assigned. Applying GCP and GCDMP principles, the CDM manages the protocol/study specific tasks including coordinating clinical and laboratory database deliverables, working with collaborators on data content requirements, leading data quality and closeout activities throughout the data management lifecycle. The CDM adheres to SCHARP Standard Operating Procedures (SOPs), Work Practice Guidelines (WPGs), applicable clinical trial regulations, and study confidentiality requirements and functions with moderate supervision in operational and technical matters within defined procedures and practices.

 

PLEASE NOTE: This position is temporary, 6 months. At this time we do not anticipate conversion to regular employee at the end of the contract period. 

Responsibilities

The Clinical Data Manager (CDM) will manage study/protocols with moderate supervision from senior staff and/or departmental leadership and will use judgment in making decisions regarding routine data management, quality control and liaison tasks. The CDM is the primary SCHARP contact for study/protocol specific implementation, operation, and closeout phases and is responsible study communication, documentation, and training on data collection and management activities for domestic and international research sites for assigned protocol/study(s).   The CDM is a member of the protocol/study team coordinating with both internal and external partners and collaborators to ensure the relevant data are collected and cleaned to meet the needs of the protocol/study and research objectives.


For the more experienced CDM, they may participate in training and orientation of new CDMs when appropriate, and may serve as a CDM mentor. Assignment of projects/trials is commensurate with previous experience and can be assigned across scientific areas or study phases. They will be coordinating larger, more complex studies and/or a larger volume of studies with minimal assistance.

  • Manages study/project implementation including but not limited to leading SCHARP team members through CRF, lab, and other data collection processes, reporting and analysis requirements, study/project documentation and training
  • Effectively manage assigned protocol/study, establish timelines and milestones, monitor and communicate ongoing status and progress
  • Ensure rapid resolution of issues/problems using appropriate internal and/or external resources. Track and manage issues escalating to the appropriate level in a timely manner.
  • Participate in development of protocol/study from draft protocol to optimize collection of accurate and high-quality data
  • Work with project sponsors, stakeholders and SCHARP team members to define project requirements, scope, risks, staffing requirements, organization and approach
  • Act as subject matter expert for data management issues between SCHARP study teams and external domestic and international research sites for assigned studies
  • Assist in development of Case Report Forms (CRFs) for assigned studies
  • Assist in the design of the protocol/study specific database for assigned studies
  • Assist in the maintenance of the study database including routine revisions or additions to include the design and/or modification of routine and existing study database edit check programs for assigned studies
  • Perform User Acceptance Testing (UAT) for assigned studies
  • Monitor study data to insure the quality and completeness of the data submitted by implementing quality control procedures
  • Generate QC reports for site review and correction as well as a variety of other reports as required
  • Evaluate study data for protocol compliance
  • Assist in the maintenance of documentation of the study database and other related data management programs and/or applications
  • Assist in the review of new and revised departmental SOPs and WPGs
  • Ensure that SCHARP meets its obligations in accordance with Good Clinical Data Management Practices (GCDMP)
  • Perform other duties as assigned

Qualifications

Minimum qualifications

 

Level II

  • Bachelor’s degree or equivalent, preferably in a health-related or scientific discipline
  • 4+ years’ experience in the pharmaceutical/clinical research environment as a Clinical Data Manager
  • EDC experience required
  • Demonstrated expertise in relevant clinical data management activities
  • Knowledge of clinical research, FDA & ICH, GCP, GCDMP, SDTM and related regulatory requirements
  • Familiarity with all phases of clinical trials and ability to adapt to study requirements
  • Experience in clinical trial and regulated research settings
  • Demonstrated problem-solving skills. Self-motivated and able to work independently using strong organizational, project and time management skills
  • Strong written and oral communication skills
  • Proficient with MS Office software

 

Level III

  • Bachelor’s degree or equivalent, preferably in a health-related or scientific discipline
  • 6+ years’ experience in the pharmaceutical/clinical research environment as Clinical Data Manager
  • EDC experience required. Working knowledge of Medidata Rave required
  • Demonstrated expertise in relevant clinical data management activities
  • Knowledge of clinical research, FDA & ICH, GCP, GCDMP, SDTM and related regulatory requirements
  • Familiarity with all phases of clinical trials and ability to adapt to study requirements
  • Experience in clinical trial and regulated research settings
  • Demonstrated problem-solving skills. Self-motivated and able to work independently using strong organizational, project and time management skills
  • Experience in facilitating and building consensus in an interdisciplinary team environment and able to build successful working relationships with a wide variety of collaborators
  • Strong verbal and written communication skills
  • Proficient with MS Office software

 

 

Preferred qualifications

Level II

  • Working knowledge of Medidata Rave highly desirable
  • Prior experience in HIV or infectious diseases clinical trial operation management and/or protocol development preferred
  • Experience with managing immunology, infectious disease and/or virology research projects desired
  • Familiarity with project management software desirable

 

Level III

  • Experience with managing immunology, infectious disease and/or virology research projects highly desired
  • Prior experience in HIV or infectious diseases clinical trial operation management and/or protocol development highly preferred
  • Experience using SAS and relational databases (e.g. MS SQL Server, MS Access, or Oracle) preferred
  • Familiarity with project management software desirable

 


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Clinical Research Coordinator I - Hill Lab

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 19018

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The position will work directly with an Assistant Professor in the Infectious Disease Sciences Program in the Vaccine and Infectious Disease Division to provide support to the Principal Investigator and research staff in the development, implementation and management of his diverse research portfolio, including research studies and clinical trials.


The Clinical Research Coordinator (CRC) will be responsible for providing support on all aspects of research study and clinical trial development and implementation. Primary responsibilities of the CRC will include assistance with the planning, coordination, implementation, and close-out (e.g. presentation of data, manuscript writing) of industry-sponsored clinical trials, in addition to retrospective and prospective observational or investigator-initiated interventional studies. Additional responsibilities will include communicating with internal and external collaborators and supporting study personnel in the preparation of regulatory documentation and audits if applicable.


Under the supervision of the Assistant Professor, the CRC will manage a portfolio of clinical research projects and will be required to perform their responsibilities with a high level of independence within the scope of study protocol(s) and institutional guidelines. The position will include interaction with patients, physicians, researchers, and other clinical providers and support staff within and outside of the Fred Hutch/ Seattle Cancer Care Alliance (SCCA) / UW system including the SCCA Patient Care Services.

Responsibilities

  • Prepares study start-up documentation including FDA submissions, eligibility checklists, study-specific clinic orders and study calendars
  • Research, maintain, analyze, and abstract patient clinical trial data from pre-study background (e.g., previous diagnoses and treatments) through clinical trial participation and long-term follow-up
  • Ensures patient eligibility requirements for clinical trials are met, assists in patient enrollment, screens and registers patients on study
  • Understand and interact with departments and automated electronic medical record systems throughout Fred Hutch/SCCA/UW system to ensure timely and complete delivery of data
  • Track status of potential and active clinical trial participants
  • Create and maintain the study’s manual of operations and laboratory manual
  • Create and maintain a REDCap database or equivalent for collection of study data. Abstracts data from medical records to complete study-specific case report forms. Maintains shadow chart with source documents. Assists in the development of data acquisition forms and instructions for completion.
  • Schedules study related clinic procedures such as blood draws, infusions and treatment according to protocol requirements; coordinates with clinic staff to ensure proper documentation and timing of research-related procedures
  • Coordinate and support regularly scheduled Sponsor or institutional monitoring visits to ensure quality and completeness of data. Responds to all findings and implements corrective action as necessary.
  • Coordinate long-term follow-up evaluations and data collection with clinical trial participants, SCCA, and participants’ local physicians
  • Serve as a liaison and reference resource to Physicians, Investigators, other staff members, and other organizations with questions about data collection or protocol procedures and requirements
  • Coordinate special projects regarding data collection, analysis, output, and presentation
  • Ensures compliance with ongoing reporting requirements to the Food and Drug Administration, National Institutes of Health, Human Subjects Committee, Institutional Review Board, Pharmaceutical Companies, and other agencies, to include annual reports, study amendments, safety reports, and unanticipated problem/noncompliance reports

Qualifications

  • BA/BS in a life sciences field of study required
  • Applicant must have one to two years of research or related experience
  • Previous experience in oncology research and clinical data collection is preferred
  • This position requires excellent organizational skills, attention to detail, ability to problem solve and to prioritize multiple competing tasks in a dynamic environment
  • Collaborative focus is essential, as well as strong written and verbal communication skills, including computer skills
  • Ability to work in teams and independently, flexible hours at times in support of clinical trials and regulatory and related compliance

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Clinical Research Coordinator I --Infectious Disease Sciences

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 18932

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The incumbent will participate in the planning, coordination, and implementation of complex investigator-initiated, industry-sponsored, and cooperative group clinical research studies involving human subjects in the Infectious Disease Sciences Program. This individual will work with a diverse team, but have a high level of independence within the scope of study protocol(s) and institutional guidelines. The team member will have patient facing responsibilities and participate in both investigator initiated and pharmaceutical industry trials among cancer patients. Collaborative skills are a must and experience with clinical trials desired.

Responsibilities

Study Conduct / Clinical Research Practice

  • Work independently in performing daily responsibilities required to plan and execute investigator driven/industry-based clinical research trials and non-intervention protocols
  • Coordinate research and administrative activities related to studies, ensuring all projects are completed according to project timelines
  • Serve as project liaison, representing the project to other center departments, funding sources, affiliated individuals or institutions, and outside organizations
  • On assigned projects, act as the main protocol resource person for the investigator and/or research sponsor, research subjects, local and central labs, monitors, primary care teams, and investigational pharmacy staff
  • Collaborate with investigators and coworkers to ensure completion of study activities
  • Train others as needed and develop standard operating procedures (SOP) or other necessary documents for standardized study conduct
  • Screen and recruit subjects either within the consortium or the community dependent upon study specific requirements, enroll, and follow research subjects, complete case report forms (CRFs), place physician orders, coordinate research study visits, communicate with the primary care teams, investigational pharmacy staff and research subjects
  • Ensure accurate enrollment records are maintained and up to date
  • Coordinate specimen collection, transport, processing, storage, and shipment procedures according to protocol requirements. Track and maintain research supplies.
  • Create source documents or CRFs as needed to promote efficient data collection and entry
  • Review CRFs to ensure completeness, accuracy, and compliance with Good Clinical Practice
  • Identify and report any adverse events in accordance with protocol, regulatory guidelines, and institutional policy
  • Manage the production of study kits

 

Protocol Development and Implementation

  • Help develop and review research protocols for feasibility and collaborate with study leadership to develop the study budget and implementation plans
  • Develop and maintain tools for study implementation, which may include data collection tools, study reference materials, and study specific orders. Revise and utilize tools as necessary to fulfill the aims of the clinical trial.

 

Budget and Billing

  • Prepare requests for research prices on study activities and coordinate the research billing start-up process
  • Review, reconcile, and approve research study bills. Work closely with the IDS fiscal staff to ensure accurate research billing and reimbursement

 

Regulatory Compliance and Documentation

  • Facilitate protocol monitoring visits and collaborate with study monitors to resolve data discrepancies and procedural issues
  • Provide input to the regulatory coordinator on protocol document submissions and continuing review reports
  • Prepare or assist in preparing consent forms, continuation review reports, protocol modifications, serious adverse event reports, and other study reports

 

Other Duties Which May Be Required:

  • Perform retrospective chart review as required
  • Travel for investigator meetings
  • May require weekends and holiday coverage for clinical studies
  • Other duties as assigned

Qualifications

  • BA/BS in a life sciences field of study required
  • Applicant must have at least one year of research or related experience
  • This position requires excellent organizational skills, attention to detail, ability to problem solve and to prioritize multiple competing tasks in a dynamic environment
  • Collaborative focus is essential, as well as strong written and verbal communication skills, including computer skills
  • Experience in clinical trials coordination setting
  • Computer experience including electronic CRF, MS Office including Excel, Outlook, PowerPoint, and Access
  • Excellent written and communication skills, attention to detail, high-level organization, leadership ability, and the flexibility to work in collaboration with a multi-disciplinary team
  • Previous experience in oncology research and clinical data collection is preferred
  • Prior experience with EPIC is desirable
  • Knowledge using REDCap databases is desirable
  • Certified Clinical Research Coordinator (ACRP), Certified Clinical Research Professional (SOCRA), or equivalent certification is preferred

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Clinical Research Coordinator II - J. Hill Group

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 18273

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The position will work directly with an Assistant Professor in the Infectious Disease Sciences Program in the Vaccine and Infectious Disease Division to provide support to the Principal Investigator and research staff in the development, implementation and management of his diverse research portfolio, including research studies and clinical trials.


The Clinical Research Coordinator (CRC) will be responsible for providing support on all aspects of research study and clinical trial development and implementation. Primary responsibilities of the CRC will include assistance with the planning, coordination, implementation, and close-out (e.g. presentation of data, manuscript writing) of industry-sponsored clinical trials, in addition to retrospective and prospective observational or investigator-initiated interventional studies. Additional responsibilities will include communicating with internal and external collaborators and supporting study personnel in the preparation of regulatory documentation and audits if applicable.


Under the supervision of the Assistant Professor, the CRC will manage a portfolio of clinical research projects and will be required to perform their responsibilities with a high level of independence within the scope of study protocol(s) and institutional guidelines. The position will include interaction with patients, physicians, researchers, and other clinical providers and support staff within and outside of the Fred Hutch/ Seattle Cancer Care Alliance (SCCA) / UW system including the SCCA Patient Care Services.

Responsibilities

  • Assist the research manager with preparing start-up documentation including IRB documents, eligibility checklists, study procedures/SOPs, study-specific clinic orders and study calendars (if not completed by the Clinical Research Manager)
  • Screens and registers patients; ensures eligibility requirements are met
  • Ability to consent patients and assures consent forms are completed correctly and in entirety
  • Schedules study related clinic procedures such as blood draws, infusions and imaging according to protocol requirements; coordinates with clinic staff to ensure proper documentation and timing of research-related procedures
  • Perform review of medical charts using ORCA/MINDscape and enter data in REDCap, Excel or other study-related databases
  • Abstracts data from medical records to complete study-specific case-report form (CRFs) (electronic and/or paper) in timely and accurate manner; maintains shadow chart with source documents
  • Maintain study and specimen tracking and inventory records for biospecimens pulled from repository
  • Assemble study kits for clinical trials
  • Perform basic processing and banking of lab specimens and associated record keeping
  • Collaborates with study sponsor/consortium delegate to assist with study monitoring visits and responds to findings
  • Creates and maintains patient tracking tools; communicates status to investigators, management and relevant departments
  • Manages study documentation throughout study life cycle including IRB annual renewals, modifications, patient study charts and regulatory binder
  • Liaises with study sponsor, investigator(s), research manager and members of study team to communicate timelines, expectations and study status
  • Acts as a resource to physicians, investigators, other staff members, and other organizations regarding protocol procedures, data collection requirements and other study related operations
  • Keeps knowledge and skills current by completing mandated training and attending meetings with the study team and the Consortium, such as the monthly coordinator meeting, relevant lectures, faculty and administrative presentations, and other opportunities of interest
  • Perform other duties as assigned

Qualifications

  • Bachelor’s degree in scientific/medical field or equivalent experience/education. Minimum of three years post-bachelor's experience in clinical study/trials coordination or related field.
  • Clinical research related certification is preferred
  • Experience with industry-sponsored clinical trials and documentation of case report form (eCRF) in study electronic data capture (EDC) system
  • Ability to work in teams and independently, flexible hours at times in support of clinical trials and regulatory and related compliance
  • Strong attention to detail and project management skills and experience is required
  • Well-organized and ability to juggle numerous tasks, often with conflicting and competing deadlines
  • Strong written and verbal communication skills
  • Strong computer skills, including proficiency in the Office Suite, and experience working with excel and databases (preferably REDCap)
  • Knowledge of federal regulations and guidelines that govern clinical research, including GCP and human subjects research

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Clinical Trial Assistant/Program Assistant--J. Hill Group

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 18948

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.



This is a position to assist in recruiting and monitoring participants for a variety of research studies and clinical trials focused on infectious diseases in individuals with cancer. This position will support an Assistant Professor in the Infectious Disease Sciences Program in the Vaccine and Infectious Disease Division.

Responsibilities

This position will work under the direction of the Principal Investigator. The incumbent will perform functions requiring knowledge and skills specific to the ongoing clinical research protocols, including but not limited to:

  • Assist the clinical research study coordinator in study-related tasks
  • Perform review of medical charts using the electronic medical record (ORCA/MINDscape) and enter data in REDCap, Microsoft Access, Excel or other study-related databases
  • Maintain study and specimen tracking sheets
  • Assemble study kits
  • Assist with processing and biobanking of biologic specimens and associated record keeping
  • Assist with retrieving and transporting biologic specimens from the UW Medical Center, Seattle Children’s hospital, and Seattle Cancer Care Alliance
  • May perform other duties as assigned

Qualifications

Required:

  • High school graduation or GED
  • Minimum of one-year experience in a related field
  • Must be competent working with Office Suite, particularly with Excel. It is expected that the incumbent will be familiar with extracting data from a database and with data filtering.
  • Strong written and verbal communication skills
  • Attention-to-detail is required for the position


Preferred:

  • BA/BS degree
  • Previous experience working in a healthcare setting and with patient charts and biologic
    specimens

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Clinical Trial Assistant/Program Assistant-Infectious Disease Sciences

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 18964

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The Infectious Disease Sciences Program at the Fred Hutchinson Cancer Research Center is seeking a full-time Clinical Trial Assistant (payroll title: Program Assistant I) to perform any of a variety of administrative and/or clinical responsibilities in support of two or more studies. 


This position will work under the direction an Infectious Disease Sciences Program faculty member and support multiple faculty members’ research/studies.  The incumbent will perform functions requiring knowledge and skills specific to the program studies and to clinical research. 

Responsibilities

  • Place orders/requisitions in inpatient and outpatient setting
  • Put together sampling kits and distribute to study sites and/or patients
  • Complete patient questionnaires
  • Collect data from various sources, including medical chart review, as requested and assist in maintaining databases(e.g. REDCap, Microsoft Access/ Excel or other study-related databases)
  • Contact patients via phone and/or email for study related procedures
  • Shipping and tracking of specimens
  • Perform basic laboratory procedures on collected samples
  • Transport specimens, if necessary, utilizing universal precautions
  • Perform data entry for CRFs and review data prior to entering to ensure its credibility
  • Perform specimen collection procedures for various studies (not including blood draws)
  • Copy medical records, and send out reports via fax or e-mail
  • Practice infection control, isolation techniques, and universal precautions
  • Participate and prepare data for research meetings
  • Assist with study related monitoring visits
  • Be willing to perform other duties as requested or assigned by study staff or P.I.
  • Maintain HIPAA, Good Clinical Practice and other clinical research training requirements

Qualifications

  • BA/BS in biological sciences or other field, with an interest in clinical research and healthcare
  • Excellent written and verbal skills required
  • Must be able to use Microsoft Office Suite (Outlook, Excel, Word, and Access) and have the willingness to learn new software programs as necessary. Demonstrate a professional, positive attitude when working with patients.
  • Highly motivated and independent
  • Strong written and verbal communication skills


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Clinical Trials Physician, HVTN and CoVPN

FH Vaccine and Infectious Disease Division
Category: Staff Scientist
Seattle, WA, US
Job ID: 18401

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   


 

The HIV Vaccine Trials Network (HVTN) is the world’s largest publicly funded multi-disciplinary international collaboration facilitating the development of vaccines to prevent HIV/AIDS. The HVTN conducts all phases of clinical trials, from evaluating experimental vaccines for safety and immunogenicity to testing vaccine efficacy and is housed at the Fred Hutchinson Cancer Research Center (Fred Hutch). The COVID-19 Prevention Network (CoVPN) was formed by the National Institute of Allergy and Infectious Diseases (NIAID) at the US National Institutes of Health to respond to the global pandemic. Using the infectious disease expertise of their existing research networks and global partners, NIAID has directed the networks to address the pressing need for vaccines and monoclonal antibodies (mAbs) against SARS-CoV-2. 

 

The Clinical Trials Physician plays a key role in providing scientific and clinical oversight and project management for the development and implementation of HIV vaccine and monoclonal antibody trials. We are looking for a physician with active interest in early phase trials who will work with the NIH and other developers in translating preclinical to clinical development. Clinical trials physicians report directly to HVTN leadership. Some experience with early phase trials; knowledge of preclinical toxicity models is desirable but not mandatory.

Responsibilities

  1. In collaboration with Network Principal Investigators and CoVPN and HVTN leadership, provide scientific review and input into concept and protocol development
  2. Manage multidisciplinary teams and institutions organized around the development and implementation of HIV and SARS-CoV-2 vaccine and monoclonal antibody protocols
  3. Represent the Network in interactions with Principal Investigators, vaccine developers, and other vaccine research and public health organizations involved in HIV and SARS-CoV-2 vaccine discovery
  4. Contribute to a core capacity for review and summary of scientific literature and analysis related to key issues for trial design
  5. Manage timelines for protocol development and implementation, to assure timely start dates for clinical trials. This includes process development and manufacturing of novel products
  6. Participate in the review of safety data from all phases of vaccine and monoclonal antibody clinical trials; this includes providing clinical input into the design of clinical monitoring plans and serving as medical monitor for clinical trials
  7. Other duties as assigned

Qualifications

  • A physician (M.D. or equivalent degree) is required
  • Preference will be given to those applicants with experience in clinical trials and to those applicants with training in phase 1 or preclinical evaluations of vaccines or antibodies
  • Board certification in internal medicine, family practice, pediatrics, preventive medicine, or infectious disease is desirable
  • The ideal candidate should:
    • be highly organized
    • have exceptional written and verbal communication skills
    • have experience managing multidisciplinary teams
    • be able to handle challenging workloads and multiple concurrent projects
    • be proficient with standard business productivity software, including word processing, spreadsheet, presentation graphics, and database applications

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

EDC Report Programmer

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18710

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking an EDC Report Programmer role to support both the EDC Programming and Clinical Data Management teams through the development of data reporting requirements and the programming of study reports using Business Objects or other software package(s). This position will also translate data management specifications for data entry screens, edit checks, custom functions, data integrations, and test plans for clinical study builds in the Clinical Data Management system.

Responsibilities

  • Configure reports using of Medidata Rave Business Objects and other software
  • Create standard, study-specific, and ad hoc reports with high attention to detail, accuracy, and timeliness
  • Test and debug reports as well as maintain version control on production reports and scripts
  • Document requirements related to all data and reporting needs such as dashboards, scorecards, reports, ad hoc queries, and other data needs
  • Create user acceptance testing (UAT) criteria for reports. Validate reports against UAT criteria
  • Configure and program clinical trial forms, visit schedules, edit checks and other study requirements in EDC systems using applied knowledge or programming and data standards
  • Performs verification of quality and completeness of study deliverables prior to release
  • Performs peer review for configuration and programming completed by other EDC programmers for both new study builds and post-production changes
  • Support EDC programming requests from study teams as assigned, applying knowledge of EDC tools and data standards to complete requests in the timelines defined
  • Supports other activities as assigned

Qualifications

Minimum qualifications

  • Bachelor’s degree in computer science, or a scientific, technical, or health-related field
  • At least 3 years of experience is required in report programming
  • Demonstrated programming skills (SQL, or similar programming experience)
  • Fundamental understanding of clinical trials
  • Working knowledge of relational database management system
  • Excellent written & oral communication skills including grammatical/ technical writing skills
  • Effective time management and organizational skills
  • Must work well independently and be self-motivated
  • Candidates should be detail-oriented with strong analytical and critical thinking skills
  • Experience in good clinical data management practices in health research
  • Experience with EDC software
  • Experience with Data Management tools or best practices


Preferred qualifications

  • Experience working in a biomedical laboratory and/or experience with clinical trials and data management


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

IT Program Manager I

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18854

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The Bedford Lab at the Fred Hutch is seeking a Program Manager to help lead our efforts in genomic epidemiology, with a focus on project management for the Nextstrain Platform and the implementation of our Bill and Melinda Gates Foundation grant through the Africa Pathogen Genomics Initiative.

Responsibilities

Project management for Nextstrain and the Nextstrain Africa PGI Grant

  • Building and maintaining partnerships with public health labs and departments of health, both within and outside the Africa PGI consortium, including maintaining a basic CRM (customer relationship management) spreadsheet
  • Ensuring that the voice and needs of public health users is brought to Nextstrain team, to ensure development priorities are aligned with needs of public health
  • Act as a frontline responder to various partners and Nextstrain users to respond to their needs and answer basic questions
  • Grant management and administration for the Africa PGI grant, including managing goals of grant, project timelines, interfacing with funders, and reporting
  • Developing and keeping updated a product roadmap specifying development priorities and user stories
  • Supporting interviews with public health entities to establish use cases for Nextstrain
  • Leading weekly standups with an interdisciplinary team of scientists, researchers, and software developers, and designers
  • Assisting in development of documentation and high-level tutorials
  • Supporting development of grant applications and funding proposals


General Bedford lab responsibilities

  • There are some additional, more general responsibilities to cover work in the Bedford Lab, including organization of lab meetings and purchasing of capital equipment

Qualifications

Minimum qualifications:

  • BA in relevant technical field
  • Minimum 3 years related experience, or equivalent education, whether in an academic or professional setting
  • Experience working with public health departments or labs, and managing relationships with these partners, if possible, in cross-cultural environments
  • Experience working on grant-based projects and in grant reporting and administration
  • Self-motivation and enthusiasm about taking a hands-on approach to collaborative scientific discovery efforts and software development
  • Excellent written and verbal communication skills
  • Experience in program or project management
  • Willingness to learn basics of software development, particularly using Python, in order to effectively work with Nextstrain software developers and public health partners using Nextstrain

 

Desired qualifications:

  • MPH in Epidemiology or other relevant field
  • Experience or interest in genomic epidemiology and/or phylodynamics
  • Experience or interest in leveraging software for public health
  • Experience building cross-cultural partnerships
  • Experience working in software development or with software developers
  • Experience with any programming language (e.g., Python, R, etc.) is helpful, but not required


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Lab Technician II

FH Vaccine and Infectious Disease Division
Category: Laboratory Research Sciences
ZA-Cape Town
Job ID: 18992

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


Since 2001, Fred Hutch has led an array of distinctive research activities in partnership with colleagues in South Africa to accelerate the development of a preventive HIV vaccine and improve the diagnosis, prevention, and treatment of cancer and infectious diseases worldwide. In 2013, Fred Hutch opened the state-of-the-art Cape Town HVTN Immunology Laboratory to serve as a base for HIV vaccine trials in South Africa. The HIV Vaccine Trials Network, or HVTN, a Hutch-based international collaboration of scientists and educators, opened two major trials in 2016 to test strategies for preventing HIV infection, including a study of a candidate vaccine which, if shown to be at least 50 percent protective, could become the world’s first licensed HIV vaccine.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

This position is responsible for monitoring all specimen activities for the laboratory including specimen requests, tracking, receipt, inventory and shipping. This position will also assist with laboratory procurement, inventory management, equipment management and other laboratory work as needed. Responsibilities include:


Sample Management and Repository
Work with the CHIL Repository Technician and Laboratory Manager to:

  • Receive, store and ship clinical specimens in accordance with regulations (i.e. IATA), Good Clinical Laboratory Practice (GCLP), and Standard Operating Procedures (SOP)
  • Track specimens and store laboratory samples using a computerized LIMS system and work with system programmers to maintain the inventory database
  • Pull specimens as needed for laboratory assays
  • Assist with repository audits as needed


Sample Processing and Laboratory Assays

  • Receive, process, and store research specimens following established SOPs. Sample processing will involve blood processing for peripheral blood mononuclear cells (PBMC), serum, plasma, as well as other blood processing or processing of other sample types
  • Assist with thawing and counting of specimens as needed

 

Laboratory Operations

  • Work with the Laboratory Manager to coordinate repairs and service of lab equipment (e.g., pipettes) and assist with obtaining quotes and purchasing of equipment and ensuring the equipment inventory is up to date
  • Provide support for laboratory inventory management, assisting with purchasing of laboratory supplies and reagents, working with the inventory database and supporting continuous improvement processes
  • Assist Quality Assurance Associate with review of laboratory documentation as needed
  • Share on-call duties with lab personnel to respond to equipment alarms in a timely manner after normal work hours (off-hours)
  • Contribute to the development of the laboratory environment (e.g. laboratory safety)
  • May support additional laboratory work, facilities, and administrative work as needed

 

General Duties

  • Follow lab protocols and standard operating procedures (SOPs); conduct all work according to Good Clinical Laboratory Practice (GCLP) guidelines and auditable-standards, ensuring accurate and timely reporting and record keeping
  • Attend and participate in appropriate laboratory meetings
  • Other duties, as required

Qualifications

  • Laboratory Technician diploma/certificate 5+ years of experience in a routine or research laboratory setting
  • Experience with Specimen Processing (especially PBMC processing) and LIMS systems strongly preferred
  • Experience working under GCLP guidelines desired
  • Experience in Microsoft Office, especially Word, Outlook and Excel desired
  • Meticulous attention to detail
  • Good numeracy, literacy and organizational skills
  • Ability to follow lab protocols and Standard Operating Procedures
  • Experience with computerized systems for labs
  • Good communication skills and an interest in learning
  • Good interpersonal and time management skills and ability to work in a team
  • Willingness to be flexible in working hours, including working evenings and weekends as needed
  • Motivation and adaptability with a keen interest in the HIV field
  • Ability to lift 20kg
  • Experience working with LN2 and ultralow freezers will be given preference
  • Completion of IATA shipping certification is required during the first six months

Laboratory Manager

FH Vaccine and Infectious Disease Division
Category: Laboratory Research Sciences
ZA-Cape Town
Job ID: 18165

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

Since 2001, Fred Hutch has led an array of distinctive research activities in partnership with colleagues in South Africa to accelerate the development of a preventive HIV vaccine and improve the diagnosis, prevention, and treatment of cancer and infectious diseases worldwide. In 2013, Fred Hutch opened the state-of-the-art Cape Town HVTN Immunology Laboratory to serve as a base for HIV vaccine trials in South Africa. The HIV Vaccine Trials Network, or HVTN, a Hutch-based international collaboration of scientists and educators, opened two major trials in 2016 to test strategies for preventing HIV infection, including a study of a candidate vaccine which, if shown to be at least 50 percent protective, could become the world’s first licensed HIV vaccine.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


 

The purpose of this position is to oversee the laboratory physical space and equipment. The Lab Manager oversees equipment maintenance and smooth functioning of the physical space and building facilities and to manage laboratory projects under the direction of the laboratory management. This position will work independently in performing daily responsibilities, referring issues on as necessary. Skills and knowledge will be applied in coordinating operational and administrative activities necessary to smooth functioning of a clinical research laboratory.

Responsibilities

Manage Lab Facilities and Equipment (30%)

  • Oversee the laboratory facilities, including specialized HVAC and electrical systems, the generator and UPS. Coordinate and oversee regular maintenance and repairs and troubleshoot problems with assistance from the off-site facilities company.
  • Oversee and manage the 24hr on-call system and handle queries from personnel when laboratory alarms are triggered. Attend to high-level emergencies 24/7, supported by the lab team.
  • Coordinate purchase and shipment/receipt of laboratory equipment to ensure laboratory is well- equipped at all times
  • Oversee and coordinate equipment maintenance, repairs, purchases and usage, troubleshooting equipment that is not performing
  • Formally document equipment maintenance, trends and other parameters to ensure functioning according to GCLP standards
  • Manage installation of new laboratory equipment, overseeing processes such as verification, qualification and validation
  • Monitor and maintain lab space and equipment, ensuring that current laboratory resource needs are met and future program resource needs are anticipated
  • Maintain good working relationships with key service providers that support the laboratory
  • Monitor and manage service level agreement compliance by service providers and ensure timely annual agreement renewals


Oversee Lab Inventory (20%)

  • Monitor lab reagents and consumables, insuring inventory systems are in place and kept up to date and accurate at all times
  • Obtain quotes and order lab reagents and consumables as needed
  • Assist with preparation of and adherence to lab budgets, performing cost analyses as needed


Repository Management (20%)

  • Oversee the specimen repository, ensuring detailed organization and proper storage of all clinical trial specimens according to GCLP guidelines
  • Ship, receive and handle specimens according to IATA and GCLP guidelines and using the lab LIMS systems
  • Train lab staff on proper specimen handling to maintain cold chain at all times
  • Supervise lab staff when receiving and accessing specimens


Laboratory Safety and GCLP Compliance (30%)

  • Address all Environmental Health & Safety issues and ensure laboratory compliance at all times
  • Review lab documentation, performing QC checks to ensure compliance
  • Draft new laboratory SOPs and edit and review existing laboratory SOPs, ensuring they are kept up- to date
  • Prepare files for audits and attend audits as requested, assisting in addressing any issues raised at the audits
  • Oversee documents required to satisfy regulatory requirements

Qualifications

Education, certification, qualifications and experience needed:

  • BTech, BA or BSc in a related field required, preferably Biomedical Technology or equivalent diploma (Clinical Pathology, Haematology, Microbiology or Immunology)
  • Minimum of ten years of experience in a routine or research laboratory setting; lab management experience
  • Familiarity with the function and troubleshooting many types of laboratory equipment
  • Experience working in a laboratory environment according to Good Clinical Laboratory Practices


Competencies / job specifications required to do the job:

  • Technologically-inclined with extensive knowledge of and experience troubleshooting lab equipment and systems
  • In-depth knowledge of quality assurance, quality control and best laboratory practices
  • Excellent attention to detail
  • Effective communication and interpersonal skills; works well in a team environment
  • Self-starter that works independently
  • Good time management and works within set deadlines
  • Flexible and adaptable to the changing needs of a dynamic environment with a desire to learn

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Post-Doctoral Research Fellow - Pancera Lab

FH Vaccine and Infectious Disease Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 18749

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


 

The Pancera/Stamatatos lab, within the Vaccine and Infectious Disease Division, works toward the development of safe and effective vaccines against HIV-1, malaria and other pathogens. Our major emphasis is the design of protein immunogens and understanding the immune response following vaccination or natural infection. The subgroup led by Dr. Pancera focuses on structural characterization of these immunogens and their immune responses. The laboratory utilizes a wide range of in vitro and in vivo systems and cutting-edge technologies and techniques.  Experimental approaches include high-throughput crystallography, cryoEM, specialized immunological methodologies and assays, molecular and cellular biology techniques, bioinformatics, and computational approaches. 

 

Our lab is seeking an outstanding Postdoctoral Fellow to work on a project involving the characterization of the humoral immune response following vaccination against HIV, malaria or other pathogens using X-ray crystallography and cryoEM and the designs of novel immunogens.

Responsibilities

  • Perform recombinant protein expression (coli, insect cells, mammalian cells) and purification including affinity purification, ion exchange and FPLC
  • Determine X-ray crystal structures of the proteins/antibodies complexes
  • Use Electron Microscopy for screening purposes (negative stain) and single particle cryoEM to determine the molecular structures of antigen-antibody complexes
  • Use of biophysical methods such as ITC and Bio Layer interferometry/SPR or ELISA
  • Initiate and carry out scientific projects under the supervision of Dr. Pancera
  • Develop and demonstrate a thorough understanding of the scientific literature relating to the research topics
  • Conduct and publish research in HIV structural biology

Qualifications

  • PhD in Structural Biology, Protein Chemistry, Biochemistry or a related field is required with significant expertise in X-ray protein crystallography
  • Candidates with backgrounds in areas such as protein biochemistry, and vaccine development are strongly encouraged to apply
  • On-hands experience with diverse aspects of Molecular Biology is required
  • Experience in X-ray crystallography including up-to-date knowledge of relevant programs including CCP4, and Phenix packages, protein purification, protein characterization, and a strong publication history are strongly desired
  • Knowledge of cryoEM is not required but desirable. Additional expertise with tissue culture and immunological assays is a plus
  • The candidate must be a ‘risk taker’, show initiative, willingness to take up new skills and responsibilities, and be a team player
  • Excellent attention to details and the ability to work independently are essential to success in this position, as are good communication and organizational skills
  • The candidate must be self-motivated, able to multitask and to work within a very collaborative environment
  • Salary will be commensurate with (appropriate) experience
  • A cover letter and research statement is required

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Post-Doctoral Research Fellow, HIV Vaccine Design & Testing

FH Vaccine and Infectious Disease Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 17924

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

Responsibilities

The McGuire Lab is seeking outstanding postdoctoral fellows to work on a project involving the validating and testing of novel vaccine candidates to elicit broadly neutralizing antibodies against HIV-1.  Responsibilities include: 

  • Design and execute prime-boost immunization regimens in a humanized murine model which will serve as a surrogate for human vaccine trials 
  • Perform endpoint analyses including antigen-specific B cell sorting and serum antibody binding and neutralization assays to gain a high-resolution understanding of the immune response to immunization. 
  • To complement this analysis the candidate will perform single B cell sorting of human PBMC samples ascertain the identity of antigen-reactive naive B cells.  
  • May be required to help with SARS-CoV-2 work as needed 

Qualifications

  • PhD in immunology, biochemistry, or a related field is required and expertise in B cell immunology is highly desirable
  • Experience with conducting in vitro studies with human peripheral blood samples preferred.
  • The candidate should have a strong molecular biology background as well.
  • Experience in multicolor flow cytometry preferred.
  • The candidate must be independent, show initiative, willingness to take up new skills and responsibilities, and be a team player
  • Excellent attention to detail and the ability to work independently are essential to success in this position, as are good communication and organizational skills
  • The candidate must be self-motivated, able to multitask and to work within a very collaborative environment

Post-Doctoral Research Fellow, Mathematical Modeler

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 19140

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 

This position will work with Scientists in the Donnell Lab and the HPTN Network. 

Responsibilities

A Postdoctoral Research Fellow position with focus on development, refinement, and utilization of different classes of epidemiological transmission models is available immediately in the Vaccine and Infectious Disease Division (VIDD) of the Fred Hutchinson Cancer Research Center.  The successful applicant will be joining a dynamic multi-disciplinary group to work on methods for effective model configuration and calibration using data collected by the HIV Prevention Trials Network (HPTN) as a basis for the methodological work. Among the key objectives of the modeling work are improving the understanding of HIV transmission, informing effective public health strategies, and guiding rational development of new preventive interventions.  The position will require a substantial amount of programming and computation, good organization and communication skills.

 

To find out more, please visit: HPTN Modelling Centre and COVID-19 Model.

Qualifications

  • Suitable applicants should have a recent PhD degree in statistics/biostatistics, applied mathematics, infectious disease epidemiology, population biology, theoretical ecology or a similarly quantitative discipline.
  • Research experience in mathematical modeling of biological systems, including but not limited to modeling infectious disease transmission and population dynamics, and experience with reviewing/analyzing scientific literature is required.
  • Experience with Bayesian statistical methods of model calibration or longitudinal data analysis is a plus. 

 

Application instructions:

Please submit a cover letter describing your research interests and interest in the position, with CV and names of three references.

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Post-Doctoral Research Fellow, Viral Immunology

FH Vaccine and Infectious Disease Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 17839

Overview

Fred Hutchinson Cancer Research Center, home to three Nobel laureates, is an independent, nonprofit research institute based in Seattle. Its interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Its Vaccine and Infectious Disease Division, which is home to more than 70 faculty members, was established to facilitate and enhance the Hutch's efforts in infectious disease prevention and vaccine development.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.  



The Stamatatos Lab, investigates the development of protective antibody responses during viral infections, with emphasis on HIV-1 and SARS-CoV-2, by employing advanced Immunological, Molecular and Bioinformatic tools. The information generated from these studies is used to design immunogens to elicit similar antibody responses by vaccination.

Responsibilities

We have two positions for Postdoctoral fellows interested in:

  • Investigating the development of B cell and antibody responses against SARS-CoV-2 in adult and pediatric patients
  • Investigating the activation and expansion of B cells that produce HIV-1 neutralizing antibodies in immunized humanize murine

Qualifications

  • A PhD in Immunology or Microbiology are preferred
  • Strong background on T and/or B cell immunity, is important
  • Ability to work independently within a very collaborative environment is critical, as are strong written, communication and organizational skills
  • Salary will be commensurate with appropriate experience

Applicants must submit:

  • Cover letter discussing your interest in this position including statement of research interests and career goals
  • Include a separate attachment of at least 3 references - Names and contact information

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Post-Doctoral Research Fellow- Stamatatos Lab

FH Vaccine and Infectious Disease Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 18055

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. The Vaccine and Infectious Disease Division, which is home to more than 70 faculty members, was established to facilitate and enhance the Hutch's efforts in infectious disease prevention and vaccine development. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

The Stamatatos Lab, investigates the development of protective antibody responses during viral infections, with emphasis on HIV-1 and SARS-CoV-2, by employing advanced Immunological, Molecular and Bioinformatic tools. The information generated from these studies is used to design immunogens to elicit similar antibody responses by vaccination.

 

We have two positions for Postdoctoral fellows interested in: 1) Investigating the development of B cell and antibody responses against SARS-CoV-2 in adult and pediatric patients and 2) Investigating the activation and expansion of B cells that produce HIV-1 neutralizing antibodies in immunized humanize murine.

 

Salary will be commensurate with appropriate experience.

Qualifications

Minimum qualifications:

  • A PhD in Immunology or Microbiology are preferred.
  • Strong background on T and/or B cell immunity is preferred
  • Ability to work independently within a very collaborative environment is critical, as are strong written, communication and organizational skills

Applicants must submit:

  • Cover letter discussing your interest in this position
  • Curriculum Vitae
  • Statement of research interests and career goals
  • Names and contact information of at least three referees

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Postdoctoral Research Fellow, Bioengineering

FH Vaccine and Infectious Disease Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 18129

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

The Jia Zhu Lab has a post-doctoral position open to conduct research in immune responses in human barrier tissues.


The Postdoctoral Fellow recruited for this position will study the protective immune responses in human barrier tissue, such as skin and mucosa, against viral pathogens, including human herpes simplex virus. The candidate will participate in research activities:

  1. to expand the development of three-dimensional (3-D) ‘tissue organoids’ and/or ‘organ-on-chip’ platforms based on our new ‘skin-on-chip’ microfluidic device incorporated with a microvascular network, and
  2. to delineate viral-host interactions and understand monocytes, neutrophils and lymphocytes recruitment and function in human tissues using our in vitro tissue model system.
  3. to evaluate newly discovered antiviral drugs and compounds.

The candidate will conduct independent research and collaborate with a multidisciplinary team of researchers, engineers and clinicians, and be expected to conduct manuscript/grant writing and research presentations at local and major scientific conferences.

 

 

Qualifications

Minimum qualifications:

  • A Ph.D. in the field of Immunology, Virology or related fields and experience in a related area
  • Must be knowledgeable in modern molecular biology techniques and be proficient in microscopic imaging
  • The candidate should be highly motivated, with a strong desire to develop cutting edge technology
  • Be able to work independently in a team environment
  • Strong analytical skills, excellent written and verbal communication skills, and problem-solving skills are needed


Application instructions:

Please include a cover letter with your application, describing your research accomplishments as well as detailing your interest and suitability for this position.


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Principal Lab Programmer

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 13818

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

 

The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world.

Working here means never wondering if you are making a positive difference in the world. For the past 15 years, SCHARP has been be instrumental in eradicating diseases around the world. Recent work supporting COVID-19 studies affirms our continued importance to global health.

 

The Lab Programming team at SCHARP is looking for a lead programmer to join our team. We are a fun, egalitarian group that focuses on delivering reliable and reusable solutions.

Responsibilities

In this role, you will provide day-to-day technical leadership to an enthusiastic team of programmers; providing guidance on best practices, design, tools, and programming hygiene. This is not a management position - you will still get to be in the code most days.

 

An early project may include improving the requirements and specifications around our codebase. This will include working with the broader SCHARP Programming Unit to establish lightweight processes for validating python, 3rd party packages and our own in-house applications.

 

As a lead, you will advise on programming concepts and feasibility, as well as represent the Lab Programming team’s interests within the wider SCHARP environment.


Responsibilities may include:

  • Develop requirements and architecture for applications, processes and systems
  • Provide primary technical leadership and mentorship of a seven-person programming team
  • Design and implement data pipelines for laboratory assay data analysis
  • Development and maintenance of quality system documentation
  • Train users on application use, procedures, and data submission best practices
  • Troubleshoot and resolve lab programming-related issues
  • Take initiative and lead complex, cross-functional team projects
  • Lead team projects in best practices or process improvement
  • Develop, apply and train team in best programming practices

Qualifications

Required

  • Bachelor’s degree in Computer Science or similar technical degree
  • 7+ years of delivering applications in Python or any object-oriented programming language
  • 3+ years of experience designing and drafting requirements for applications
  • Proficiency using source code management tools (SVN)
  • Experience with relational databases (Postgres)
  • Proficient Linux user - including command line tools
  • Exemplary attention to detail: testing, meaningful comments, root cause analysis


Preferred

  • Experience designing and deploying applications using Django or Flask
  • Basic CI/CT experience (Jenkins)
  • Programming in multiple languages for a scientific or health related field
  • Python, JavaScript, Java, Perl, Unix shell, Go, C/C++
  • Knowledge of laboratory procedures for assays
  • Understanding of computerized systems validation
  • Programming support of clinical trials, statistical programming, or other scientific research

Program Assistant II

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 19072

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.


The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking a Program Assistant II to assist with the implementation of program policies and procedures, administrative support, and operational assistance for program management which involves customer/stakeholder engagements, communication and information management within cross-functional teams and planning and coordination of projects/programs. May carry out special assignments or projects in addition to defined responsibilities.

 

This is a temporary, part-time position.

Responsibilities

The incumbent works with some independence and is expected to use judgment in carrying-out duties within the framework of SCHARP Unit policies and procedures. May perform some or all of the following responsibilities:

  • Assists in the implementation of department/study policies and procedures
  • Carry-out special assignments or projects
  • Serve as department/study liaison and provide information to Center staff and outside organizations
  • Gather information and produce reports on department/study performance
  • Maintain updated policies and procedures manuals
  • Make accurate and complete postings to department/study records and maintain files and filing systems in accordance with policies and procedures
  • Prepare special and recurring reports
  • Perform clerical duties to include: drafting and word processing correspondence, reports, publications.; editing and proofreading materials; making appointments, travel arrangements, and organizing meetings
  • May monitor the program budget and report variances to supervisor
  • Perform related duties as assigned

Qualifications

  • High school graduation or GED
  • Minimum of two years’ experience with Communication Management skills, such as:
    • communicating with customers or stakeholders
    • concisely replying to the email
    • requesting additional information when needed
    • summarizing customer/stakeholder deliverables and timelines
  • Six months’ experience with Technical Understanding skills, such as:
    • familiarity with clinical trials and their management
    • familiarity with technical environments for research
  • Six months’ experience with Cross-Functional Organization skills:
    • ability to plan and coordinate activities for multiple teams (e.g. meetings, training, workshops)
    • ability to review multiple users’ calendars
    • ability to organize, store and share documentation across teams

Project Manager III - HVTN B Cell

FH Vaccine and Infectious Disease Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 19176

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The HIV Vaccine Trials Network (HVTN) Laboratory Center in the Immunology & Vaccine Development Program of the Vaccine & Infectious Disease Division is dedicated to understanding human immunity and mechanisms of vaccine-induced immune protection against HIV and SARS-CoV-2.

 

This position will be with the McElrath HVTN Laboratory. The Research Project Manager will lead detailed evaluation of B cell immune responses to candidate HIV and SARS-CoV-2 vaccines in clinical trials as well as investigations of immune responses to HIV and SARS-CoV-2 (COVID-19) infections. This individual will develop and implement novel methods, train and supervise technicians, design experiments and oversee collection and analysis of data.

Responsibilities

Reporting to the HVTN Laboratory Associate Director, the Research Project Manager will coordinate and carry out activities including but not limited to:

  • Lead, develop and conduct immune assays to assess antigen-specific B cell responses: high-dimensional multiparameter flow cytometry, FACS sorting, isolation and culturing of antigen-specific primary B cells, biochemical assays (protein gels, western blots and ELISAs), BCR sequencing and other assays as relevant.
  • Supervise, mentor, and train a team of research technicians to conduct B cell immune assays
  • Analyze flow data and results
  • Coordinate with statistical groups and internal and external stakeholders
  • Participation in both formal and informal sharing of data amongst collaborating researchers
  • Assist with external progress reports, grant applications and scientific articles
  • Coordinate establishment of new techniques in the laboratory
  • Other duties and projects as assigned

Qualifications

  • Advanced degree preferred; BA/BS with 10+ years work experience or equivalent combination of relevant work experience and post-bachelor’s education required.
  • Experience with human B cell immunology and multiparameter flow cytometry and analysis is required
  • Excellent communication (oral and written) and problem-solving skills are required
  • Duties will require working in a team-oriented research environment and in serving in a collaborative and supervisory capacity
  • A strong background in collaborative team leadership, positive communication and project completion is preferred
  • Motivation and adaptability are essential, as is a keen interest in the HIV vaccine field
  • Knowledge of human clinical trials and/or GCLP/GLP experience is required
  • Proficiency in the following computer programs is necessary: MS Office, Illustrator or other drawing program, Prism, JMP, Excel, R and/or SAS statistical analysis program, and FlowJo and/or other flow data analysis programs.
  • Hours: Must be flexible, able to work some nights and weekends
  • Special qualifications: willingness to work with biohazardous (e.g., HIV-1) materials, required


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Regional Medical Liaison

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
ZA-Soweto
Job ID: 18999

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.


The HIV Vaccine Trials Network (HVTN) is the world’s largest publicly funded multi-disciplinary international collaboration facilitating the development of vaccines to prevent HIV/AIDS. Most recently, the COVID-19 Prevention Network (CoVPN) was formed by the National Institute of Allergy and Infectious Diseases (NIAID) at the US National Institutes of Health to respond to the global pandemic. Using the infectious disease expertise of their existing research networks and global partners, NIAID has directed the HVTN to utilize their experience and expertise to address the pressing need for vaccines and antibodies against the SARS-CoV-2 virus. The mission of CoVPN is to conduct Phase 3 Efficacy Trials to prevent infection and COVID-19 disease. CoVPN will work to develop and conduct studies to ensure rapid and thorough evaluation of United States government-sponsored COVID-19 vaccines and antibodies for the prevention of COVID-19 disease.


The Regional Medical Liaison plays a key role in providing clinical support for clinical research sites (CRSs) implementing vaccine & prevention trials of the HVTN/CoVPN in Southern Africa. The position is based in Southern Africa and is part of the Clinical Development Unit, Leadership Operations Center (LOC) of the HVTN/CoVPN and reports to the Programme Lead/Protocol Team Lead. The Regional Medical Liaison is a resource for CRS staff and other LOC staff based in Southern Africa and is a liaison between Southern Africa-based clinical CRS staff, Seattle-based Clinical Safety Specialists and Clinical Trials Physicians, and Network Leadership.  The main responsibilities of the position are to be involved in the safety monitoring of trials being conducted in the region.

Responsibilities

Project Management, coordination, support and implementation (20%)

  • Provide on-call coverage of HVTN 24/7 Safety Phone
  • As needed and working in close collaboration with other Network staff, participate in teams that support the development and implementation of trial sites and clinical trials in Southern Africa; this may include contributing to the design of clinical monitoring plans
  • Other duties and assignments as requested for the overall performance of the department and company
  • Serve as the primary contact for medical related queries

 

Safety Management, Quality control, Quality Assessment Coordination (50%)

  • Conduct active monitoring and review of safety data from all phases of vaccine clinical trials; this may include serving on the Protocol Safety Review Teams (PSRTs) for clinical trials
  • Help ensure completeness, accuracy, and safety compliance of clinical data provided by CRSs, including querying sites for clarification and updates as needed during the conduct of the trial
  • Provide ongoing consultation on protocol clinical safety issues to protocol teams and to CRS and Network staff
  • Contribute to the preparation, review, and distribution of safety reports for the PSRT
  • Contribute to the preparation of reports for the Safety Monitoring Board (SMB) and Data & Safety Monitoring Board (DSMB) if applicable


Clinical Research Support, quality assurance, protocol adherence (20%)

  • Provide training to CRSs and respond to CRS queries on clinical matters related to the Network's vaccine trials, including but not limited to clinical data collection, and optimal assessment, management, and reporting of adverse events
  • Contribute to the development of clinical case report forms (CRFs), Study-specific Procedure documents (SSPs), and other protocol documents
  • As needed and working in close collaboration with other Network staff, participate in teams that support the development and implementation of the Network's trial sites and clinical trials in Southern Africa; this may include contributing to the design of clinical monitoring plans

 

Other duties as assigned (10%)

Qualifications

EDUCATION, CERTIFICATION, QUALIFICATIONS AND EXPERIENCE NEEDED

  • A medical doctor (MBChB, MBBS, MD or equivalent degree) with clinical experience in Southern Africa is strongly preferred
  • Postgraduate education in public health or clinical research or administration
  • Preference will be given to those applicants with experience in public health or a research field and to those with data management experience in international research
  • Candidate should possess familiarity with clinical trials safety data collection practices, clinical data and adverse event reporting, and regulatory requirements

 

COMPETENCIES / JOB SPECIFICATIONS REQUIRED TO DO THE JOB

  • Meticulous attention to detail
  • Good numeracy, literacy and organizational skills
  • Ability to follow lab protocols and Standard Operating Procedures
  • Clinical Research Expertise
  • Good communication skills and an interest in learning
  • Good interpersonal and time management skills and ability to work in a team
  • Willingness to be flexible in working hours, including working evenings and weekends as needed
  • Should demonstrate the ability to identify, communicate, and follow up on clinical trial conduct and clinical data issues with study sites and research collaborators

Regulatory Affairs Associate

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 18194

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center (Fred Hutch), home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first and largest cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.


The Vaccine and Infectious Disease Division (VIDD), one of five scientific divisions at Fred Hutch, addresses the growing need for treatment and prevention strategies for infectious diseases worldwide. VIDD is comprised of three research programs—Biostatistics, Bioinformatics & Epidemiology (BBE), Immunology & Vaccine Development (IVD), and Infectious Disease Sciences (IDS). The IVD Program is a large and diverse program, supporting the research of more than 20 faculty, more than 75 active grants and a research staff of more than 200. This program supports a complex portfolio of clinical trials in infectious diseases including HIV vaccine trials, COVID-19 vaccine trials, and related observational studies. The IVD Program currently has a vacancy for a Regulatory Affairs Associate.

Responsibilities

The Regulatory Affairs Associate is responsible for providing support and guidance to investigators on regulatory issues and requirements related to the conduct of clinical trials and use of investigational products. This role ensures proper oversight of clinical trials involving investigational new drugs (INDs). The Regulatory Affairs Associate serves as a liaison for PI(s)/study team and various internal/external regulatory oversight groups. This role is also responsible for coordinating submissions to local regulatory bodies including the Institutional Review Board (IRB) and Institutional Biosafety Committee (IBC) under the supervision of the Regulatory Affairs Manager.

 

Primary responsibilities:

  • Provide regulatory support to IVD Principal Investigators (PIs) working in multiple clinical trials units including the Vaccine Trials Unit (VTU), the Prevention Center (PC), the COVID Clinical Ressearch Center (CCRC) and other mobile locations
  • Write and prepare regulatory submissions including applications, renewals, amendments, consent forms, safety reports, study updates, etc. in accordance with required timelines
  • Prepare and coordinate site registration materials/submissions and assist with communications with sponsors and contract research organizations (CROs)
  • Assist in the development of project/study policies and procedures. Administer policies and procedures according to protocol, regulatory, and lab safety policies.
  • In partnership with the PI, prepare and track all clinical activity documents including IRB/IBC/site registration approvals, safety reports, deviations, laboratory certifications, staff training & licenses, monitoring notices and reports, inspections & compliance, etc.
  • Assist with sponsor monitoring visits remotely and onsite as needed
  • Create, maintain, and audit systems for tracking and implementing regulated activities at the clinical locations
  • Assure the proper management, retention, and version control of all applicable regulatory documentation including master files and amendments
  • Assist in the coordination of project activities to ensure they follow timelines and meet deadlines
  • Assist in the development of research materials
  • Perform information searches related to studies and projects
  • Provide clear and concise professional communication in response to reviewing bodies and regulatory agencies
  • Use judgment to interpret and apply federal and local regulations regarding clinical research
  • Perform other responsibilities as assigned

Qualifications

Required:

  • Bachelor’s degree
  • 3-5 years of experience working in regulatory affairs or related field
  • Previous experience in clinical trials regulatory operations with an emphasis on IND trials in a pharmaceutical, biotechnology, or academic clinical research setting
  • Experience preparing and reviewing regulatory applications, communicating with the regulatory committees, preparing for monitoring visits or audits, and assessing risk in the conduct of clinical research
  • Understanding and interpreting Good Clinical Practice and Human Subjects regulations
  • Excellent verbal and written communication skills
  • Highly organized, exhibit strong attention to detail and be able to manage multiple tasks and deadlines

Preferred:

  • Ability to work collaboratively
  • Successful candidate should be proficient in Microsoft Office Suite, Adobe, and Clinical Trials Management Systems
  • Able to work with minimal supervision and within a team environment
  • Regulatory Affairs, IRB Professional or Clinical Research certification

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Regulatory Affairs Associate - Infectious Disease Sciences Program

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 18773

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


 

The incumbent works with faculty and staff in the Infectious Disease Sciences (IDS) Program in the Vaccine and Infectious Disease Division to ensure all regulatory compliance measures are followed for clinical trials by coordinating regulatory submissions and monitoring as well as assisting with the resolution of compliance issues. The position is expected to work independently within a framework of established regulations and guidelines, and demonstrate initiative and sound judgment in problem solving, providing regulatory guidance and developing policies and procedures. Responsible for preparing IRB documents and FDA correspondence, maintaining regulatory files, and facilitates regulatory oversight for all related studies. This position has significant interactions with the PI(s), other team members, internal departments and external organizations and agencies. The position reports to the Program Operations Director in the IDS Program.

Responsibilities

Regulatory Affairs Associate responsibilities:

  • Prepare, track and maintain all correspondence and regulatory documentation required by the IRB, FDA, sponsors, and other institutional and federal oversight committees, including drafting and reviewing content as appropriate.
  • Submit all regulatory documents to the IRB and other governing bodies to maintain study compliance with GCP, institutional and federal regulations.
  • Maintain study regulatory binders and electronic files g. SharePoint, OneDrive, OnCore.
  • Perform internal audit and quality assurance checks on regulatory documents.
  • With input from PIs, study team, draft initial clinical research informed consent forms and study documents.
  • Lead study start-up: prepare and submit all required regulatory documents for new study applications; successfully open new studies from inception to accrual.
  • Prepare and present materials for monitoring visits; may serve as primary point of contact during visits.
  • Independently follow-up and resolve all issues related to regulatory concerns identified during monitoring visits.
  • Prepare and submit modifications/amendments, and continuing renewals for ongoing study maintenance in a timely manner.
  • Conduct study close-out. Be responsible for archiving regulatory documents/records, ensuring that all files are prepared for off-site storage in accordance with FDA, other applicable regulatory guidelines and program SOP.
  • Process IND external safety reports, maintain documentation of PI review and submit safety reports to the IRB as appropriate.
  • Report non-compliance and unanticipated problems to the IRB as applicable.
  • Serve as primary regulatory resource for PIs, sponsors, a study team, providing guidance on regulatory statuses, approvals and instructions regarding patient consent.
  • Serve as liaison for internal regulatory bodies (IRB, Clinical Research Support, Regulatory Affairs, etc.).
  • Stay abreast of new impacts/areas of knowledge and regulatory changes and disseminate this knowledge to the study/operations team. Work with IRB team and IDS leadership to develop standard operating procedures (SOPs).
  • Identify, develop and implement any necessary revisions to related policies and procedures.
  • Work with fiscal team/PI/study team regarding funding proposals, annual progress reports.
  • Coordinate and manage the regulatory documents from each participating site for studies where IDS serves as the IRB of record (coordinating center). Also track sites’ annual continuing reviews and alert sites to upcoming expirations to prevent lapses from occurring.
  • Manage the regulatory tracking and archive systems (e.g. SharePoint, Clinical Trials Management System, shared network drive, etc.).
  • Write and prepare regulatory submissions including applications, renewals, amendments, consent forms, safety reports, study updates, etc. in accordance with required timelines.
  • Prepare and coordinate site registration materials/submissions and assist with communications with sponsors and contract research organizations (CROs).
  • Assist in the development of project/study policies and procedures. Administer policies and procedures according to protocol, regulatory, and lab safety policies.
  • In partnership with the PI, prepare and track all clinical activity documents including IRB/IBC/site registration approvals, safety reports, deviations, laboratory certifications, staff training & licenses, monitoring notices and reports, inspections & compliance, etc.
  • Create, maintain, and audit systems for tracking and implementing regulated activities at the clinical locations.
  • Assure the proper management, retention, and version control of all applicable regulatory documentation including master files and amendments.
  • Assist in the coordination of project activities to ensure they follow timelines and meet deadlines.
  • Assist in the development of research materials.
  • Perform information searches related to studies and projects.
  • Use judgment to interpret and apply federal and local regulations regarding clinical research.
  • Perform other tasks as assigned.

Qualifications

The level of Regulatory Affairs Associate or Regulatory Affairs Associate Lead will be determined based on the qualifications below.

 

Regulatory Affairs Associate Minimum Education/Work Experience:

  • Bachelor’s degree.
  • 3-5 years of experience working in regulatory affairs or related field with emphasis on INDs and IDEs in a pharmaceutical, biotechnology, or academic clinical research setting.
  • Preparing and reviewing IND applications.
  • Communicating with FDA and preparing for FDA inspections.
  • Assessing risk in the conduct of clinical research.
  • Designing tools for the regulatory management of clinical trials.
  • Interpreting federal regulations and guidelines.

 

Qualifications:

  • Previous work experience preparing and/or reviewing study start-up documents, including IRB documentation and research protocols.
  • Knowledge of FDA, ICH/GCP guidelines.
  • Strong verbal and written communication skills working across multiple disciplinary teams.
  • Ability to adapt and adjust priorities based on changing needs, and the ability to troubleshoot and problem-solving skill.
  • Excellent time management skills and meet deadlines.
  • Working knowledge of Microsoft Suite, SharePoint, Adobe Suite, Clinical Trials Management System.
  • Ability to use discretion and maintain confidentiality.

 

Preferred:

  • Previous clinical research regulatory coordinator experience working within Fred Hutchinson Cancer Research Center or University of Washington’s institutional regulatory system.
  • Previous experience working with on-line/web-based platforms for clinical trial management systems.
  • Certified IRB Professional (CIP) certification preferred.
  • Knowledge of regulations and guidelines that govern clinical research, including but not limited to FDA regulations and Good Clinical Practice.
  • Master’s degree in regulatory affairs preferred—for Lead Regulatory Affairs Associate level.

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Research Administrator IV-Grants and Contracts

FH Vaccine and Infectious Disease Division
Category: Accounting and Finance
Seattle, WA, US
Job ID: 18955

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   


 

The HIV Vaccine Trials Network (HVTN) is the world’s largest publicly funded multi-disciplinary international collaboration facilitating the development of vaccines to prevent HIV/AIDS. Most recently, the COVID-19 Prevention Network (CoVPN) was formed by the National Institute of Allergy and Infectious Diseases (NIAID) at the US National Institutes of Health to respond to the global pandemic. Using the infectious disease expertise of their existing research networks and global partners, NIAID has directed the HVTN to utilize their experience and expertise to address the pressing need for vaccines and antibodies against the SARS-CoV-2 virus. The mission of CoVPN is to conduct Phase 3 Efficacy Trials to prevent infection and COVID-19 disease. CoVPN will work to develop and conduct studies to ensure rapid and thorough evaluation of United States government-sponsored COVID-19 vaccines and antibodies for the prevention of COVID-19 disease.

 

Job Summary
Incumbent works as a member of the fiscal team under direction of the Associate Director of Finance, referring issues and soliciting guidance as necessary. The incumbent works with limited supervision in performing work assignments. Responsible for helping maintain a positive operational relationship with subcontractor institutions and clinical research sites both in the U.S. and internationally. The incumbent serves a key liaison role and will collaborate with leadership and staff throughout the Leadership Operations Centers (HVTN and CoVPN) and Fred Hutch on issues related to subcontracts and subawards.

Responsibilities

  • Liaison for Subaward Process between Fiscal and Contracts Team and the Fred Hutch Office of Sponsored Research (OSR). Maintain good working relationship with OSR and subcontractors to process subcontracts and disseminate information in timely manner.
  • Serves as first point-of-contact for all subaward related issues in respective portfolio and assist fielding questions from other team members concerning individual portfolios.
  • Responsible for the administration of domestic and international subawards. These contracts may serve a wide variety of purposes from providing clinical sites with funding to supporting investigators involved in scientific leadership activities to funding laboratory activities.
  • Works with Associate Director of Finance and/or Fiscal Manager to ensure site support is covered and delegated to appropriate members of the team.
  • Assists in negotiating contract budgets, milestones, and terms.
  • Creates (with assistance from team) processes for tracking subcontract invoices, review, and approval processes. Design, implement, and share standards with Team to ensure all subcontract files are consistent across all sites and institutions.
  • Work with operations managers in preparing protocol costing templates and tracking each in protocol library.
  • Maintain current Leadership Award Budgets and Levels of Effort Reviewed.
  • Maintain and keep current on funding agencies’ policies, procedures and communicate these to Team members and sites. Alert PI and Associate Director of Finance and/or Fiscal Manager of concerns regarding site compliance, or other critical issues
  • Establish training tools and guidance when necessary.
  • Review monthly expenditure reports for budgets using PeopleSoft and resolve any discrepancies by working with FHCRC Accounts Payable and operations managers.
  • Work with Associate Director of Finance and/or Fiscal Manager in preparing complex financial models, reports, and/or presentations.
  • Work with Associate Director of Finance and/or Fiscal Manager in preparing applications, carry over, and prior approval requests.
  • Work with Associate Director of Finance, Fiscal Manager and/or Director of Site Operations to coordinate site pricing communications for trials managed in multiple networks.
  • Participate in meetings to share status of agreements and site issues of concern and/or risks.
  • Other duties as assigned.

Qualifications

  • Bachelor’s degree and five years of administrative experience required. Master’s degree highly recommended.
  • Experience with grants and contracts required; experience with large multi-site clinical research projects preferred.
  • Excellent quantitative/fiscal, budgeting, and written and verbal communication skills.
  • Strong computer skills—MS Word, Adobe Pro, and advanced knowledge of Excel required.
  • Excellent written and verbal communication skills.
  • Demonstrated ability to multi-task in a fast-paced, constantly evolving fiscal management environment.
  • Demonstrated ability to work effectively in a team environment as well as individually.
  • Ability to problem-solve and process information quickly.
  • A cover letter is required for this application.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Research Coordinator

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 19178

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


 

The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking a Research Coordinator.

Responsibilities

The coordinator provides support to department managers in the completion of research-related administrative tasks and policies and procedures relating to quality, regulatory compliance and internal standard procedures.  Participates in and coordinates special assignments or project activities under the direction of the department manager.  Research Coordinator positions may vary widely in the specific tasks performed as the work may be project-based and specific to the individual department or study. Responsibilities may include some or all of the following:

  • Provide administrative support for department/study policies and procedures
  • Provide administrative support in the development of procedures, work instructions and study materials
  • Execute moderately-complex special assignments or projects
  • Aid in the develop and tracking of project charters, milestones and timelines
  • Assist in the completion of internal study and regulatory documentation – may include moderate word processing, copying, scanning, filing, and routing for signatures
  • Assist in the response to regulatory and audit findings
  • Make accurate and complete postings to department/study records and maintain filing and record keeping system in accordance with policies and procedures.
  • Assist management in tracking, and prioritization of work intake and deliverables
  • Prepare departmental and study reports for delivery
  • Perform administrative or complex clerical responsibilities as required
  • Perform other duties as assigned

Qualifications

  • BA/BS in related field OR equivalent work experience
  • General working knowledge of good documentation and/or research practices
  • Strong oral and written communication skills
  • Demonstrated attention to detail

Research Intern - J. Hill Group

FH Vaccine and Infectious Disease Division
Category: Internships
Seattle, WA, US
Job ID: 19170

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.


 

The Infectious Disease Sciences program at the Fred Hutchinson Cancer Research Center is seeking an Undergraduate Research Intern to learn and work on a clinical research project.

 

This full-time summer internship will work under the direction of an Infectious Disease Sciences Program faculty member. This student will assist with ongoing prospective clinical studies and will help members of the research team with retrospective epidemiologic reviews of infections in cancer/transplant recipients. 

 

This position will provide an opportunity to learn about clinical research in the cancer patient population. The Fred Hutchinson Cancer Research Center is a unique place to work, with more than 300 faculty involved in a variety of research goals, working toward the elimination of cancer and related diseases as causes of human suffering and death.

Responsibilities

  • Assist with clinical data review for epidemiologic studies with presentation at the end of the internship

  • Perform data entry and filing

  • Writing and review of manuscripts

  • Create study documents for various studies

  • Prepare and assemble patient kits

Qualifications

  • Must have high-school degree or GED
  • Must be currently enrolled as undergraduate student in university or community college institution
  • Applicants must have excellent computer skills, including the ability to use MS word, PowerPoint and Excel
  • Strong interpersonal skills and an excellent work ethic are required
  • Applicant must be flexible and able to work independently without supervision

Research Project Manager I

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18986

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


 

The Gottardo lab is looking for a Research Project Manager for Vaccine Immunology Statistical Center (VISC) operations.

 

Led by Dr. Raphael Gottardo, the VISC partners with world-class research programs to tackle global public health initiatives in infectious disease. The VISC operates within two global research networks: the Collaboration for AIDS Vaccine Discovery (CAVD) and the Global Health Vaccine Accelerator Platforms (GH-VAP). The VISC has additional dedication to open science exemplified by their DataSpace web application.

 

The CAVD is an international network of scientists and experts dedicated to designing a variety of novel HIV vaccine candidates and advancing the most promising candidates to clinical trials.  The GH-VAP supports laboratory and clinical research to accelerate vaccine discovery and translation related to non-HIV infectious diseases, including COVID-19, TB, and malaria.


The project manager will work with the Associate Director of VISC Operations to develop a roadmap to bring each project to completion. The incumbent will oversee a diverse portfolio of projects that include pre-clinical and clinical trials. The project manager, with input from the Associate Director of VISC Operations, will coordinate activities among staff including faculty, statisticians, programmers, and data coordinators. They will also maintain collaborative relationships with external stakeholders.

Responsibilities

  • Work with teams composed of researchers, statisticians, and other project managers to define project requirements, scope of work, staffing requirements, organization, and approach.
  • Develop project milestones and timelines
  • Track project milestones and deliverables. Ensure team and stakeholders are informed of project status and issues.
  • Liaise with internal and external stakeholders on an ongoing basis
  • Intake and prioritize incoming requests
  • Organize and facilitate regular status meetings with project team, preparing and distributing minutes, agendas, and other materials as needed
  • Aid in preparation of progress report, proposals, and presentations
  • Aid in planning annual Scientific Advisory Board meeting
  • Aid in budget monitoring
  • Occasional domestic and/or international travel required

Qualifications

MINIMUM QUALIFICATIONS

  • Bachelor’s degree required
  • Minimum of three years post-master's or five years post-bachelor's related experience
  • Experience in clinical trial or regulated research settings. Experience with managing immunology, infectious disease, virology research projects, and/or data management experience, preferably in a laboratory/research setting.
  • Strong written and oral communication skills
  • Proficient with MS Office software and familiar with data management practices
  • Experience in facilitating and building consensus in an interdisciplinary team environment. Able to build successful working relationships with a wide variety of collaborators
  • Demonstrated problem-solving skills. Self-motivated and able to work independently using strong organizational, project and time management skills.

PREFERRED QUALIFICATIONS

  • Master's degree in a related field
  • Specific training or certification in project management best practices desirable
  • Familiarity with project management software and tools desirable
  • Experience in grant or proposal writing desirable


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Research Technician I-II, Human Immunology - HVTN/CoVPN

FH Vaccine and Infectious Disease Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 17727

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

 

RESEARCH TECHNICIAN I/II- McElrath Laboratory                               

This research opportunity is with the McElrath laboratory, HIV Vaccine Trials Network (HVTN) and Coronavirus Prevention Network (CoVPN).  Our lab is recruiting a research technician to primarily perform assays to characterize antiviral T and B-cell responses.   S/he will be expected to perform complex research assays, utilizing flow cytometry to evaluate vaccine-induced cellular immune responses in vaccine recipients participating in clinical trials of investigational vaccines for SARS-CoV-2/COVID-19, HIV, malaria, tuberculosis (MTB), and Ebola.  S/he will be responsible for performing and coordinating the assays with other technicians and analyzing the data.  S/he will interpret and report on experimental results and assist with data presentation. S/he will assist in writing laboratory SOPs, reports, and other documentation. S/he will report to a project manager and work closely with a technical team.

 

The HVTN’s mission is to facilitate the process of testing preventive vaccines against HIV/AIDS or other infectious diseases. The organization conducts all phases of clinical trials from evaluating experimental vaccines for safety and the ability to stimulate immune responses through to testing vaccine efficacy. The HVTN laboratory is responsible for conducting laboratory-based studies to evaluate the immunogenicity of investigational vaccines.

 

Responsibilities

  • Maintain a high level of accuracy for all work.
  • Work well as team-member, participate in positive communication, and foster an environment that allows all laboratory staff to work well together.
  • Independently perform flow cytometry, FACS sorting, and other experimental assays, such as MSD, ELISpot and ELISAs.
  • Perform flow cytometry (intracellular cytokine staining and FACS sorting), ELISPOT and MSD/Luminex/ELISAs for characterization and monitoring of T and B cell responses.
  • Proactively prepare reagents for experiments and for general lab use.
  • Troubleshoot and optimize experimental methods, results and analysis.
  • Maintain accurate documentation for experiments and quality control for the laboratory.
  • Carry out maintenance, trouble-shooting and QC of laboratory equipment.
  • Review the literature to stay informed on the HIV vaccine field or immunological assays.
  • May perform data analysis, interpretation, and statistical analyses.
  • Other duties as assigned.

Qualifications

  • A bachelor’s degree in immunology or biological science
  • 2 years of laboratory experience. 
    • Research Techn I minimum qualifications- BA/BS in a scientific field required. Must have scientific knowledge in the area of study and basic laboratory skills.  Independent research experience in addition to school lab experience is usually necessary.
    • Research Techn II minimum qualifications- Intermediate level position requires a BA/BS and 2+ years’ experience working in a laboratory. Independent research experience outside of laboratory course work is required.
  • Specific experience with flow cytometry, immunology, cellular assays, and tissue culture are preferred. 
  • Motivation, adaptability and ability to be a strong team player are essential, as is a keen interest in the HIV vaccine field.
  • The candidate must be someone with great attention to details, well-organized, self-motivated, and able to efficiently manage time and experiments. 
  • Experience in a GLP or GCLP setting or clinical experience, with strong documentation skills is also desirable. Applicants must be willing to work with biohazardous/infectious agents (e.g., bloodborne pathogens, including HIV-1) and also be flexible and willing to work some evenings and weekends. Salary will be commensurate with appropriate experience. 

Research Technician III, Human Immunology - HVTN/CoVPN

FH Vaccine and Infectious Disease Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 18095

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



This research opportunity is with the McElrath laboratory and the HIV Vaccine Trials Network (HVTN). Our lab is recruiting an entry-level or experienced research technician to perform complex research assays to characterize primarily T-cell responses utilizing flow cytometry induced by investigational vaccines or during infection with SARS-CoV-2, HIV and other pathogens, such as malaria and TB. They will be responsible for standardizing and performing novel assays, and collecting and analyzing the data. They will interpret and report on experimental results and assist with data presentation. They will assist in writing laboratory SOPs, reports, and other documentation. The technician will report to a manager and work closely with a technical team.


The HVTN’s mission is to facilitate the process of testing preventive vaccines against HIV/AIDS or other infectious diseases. The organization conducts all phases of clinical trials from evaluating experimental vaccines for safety and the ability to stimulate immune responses through to testing vaccine efficacy. The HVTN laboratory is responsible for conducting laboratory-based studies to evaluate the immunogenicity of investigational vaccines.

Responsibilities

  • Maintain a high level of accuracy for all work
  • Work well as team-member, participate in positive communication, and foster an environment that allows all laboratory staff to work well together
  • Independently perform immunological, flow cytometry and other experimental assays
  • Troubleshoot and optimize experimental methods, results and analysis
  • Lead, train or coordinate other technicians, or team members on laboratory techniques and assays
  • Review the literature to learn and trouble-shoot new methods and stay informed on the HIV/SARS-CoV-2 vaccines and immunology
  • Prepare and present written or oral progress reports concerning studies including assembly, organization, and interpretation of data
  • Maintain accurate documentation for experiments and quality control for the laboratory
  • Supervise and carry out maintenance, and troubleshooting and QC of laboratory equipment
  • May perform data analysis, interpretation, and statistical analyses
  • Other duties as assigned

Qualifications

  • Senior level position requires a BA/BS and 4+ years’ relevant experience working in a laboratory, or a Master’s degree and an equivalent experience. Requires independent research experience with immunological assays and training and supervision of other staff
  • Experience with immunology, flow cytometry, COVID, HIV/AIDS and/or cellular assays are strongly desired
  • Motivation, adaptability and ability to be a strong team player are essential, as is a keen interest in the SARS-CoV-2/COVID-19 & HIV vaccine field
  • The candidate must be someone with great attention to details, well-organized, self-motivated, and able to efficiently manage time and experiments. Experience in a GLP or GCLP setting or clinical experience, with strong documentation skills is also desirable
  • Applicants must be willing to work with biohazardous/infectious agents (e.g., bloodborne pathogens, including SARS-CoV-2 & HIV-1) and also be flexible and willing to work some evenings and weekends
  • Salary will be commensurate with (appropriate) experience

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

SAS Statistical Programmer III

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 13941

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. The Center’s five scientific divisions collaborate to form a unique environment for conducting basic and applied science. Vaccine and Infectious Diseases Division (VIDD) works to eliminate or minimize the impact of globally significant infectious diseases. Within VIDD is the Statistical Center for HIV/AIDS Research & Prevention (SCHARP), which provides statistical support and data management to researchers worldwide in the fight against HIV/AIDS with active studies in the U.S., Africa, Latin America, Asia and Europe. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   


The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking a Statistical Programmer III.

 

With guidance, the Senior Statistical Programmer provides statistical programming expertise within SCHARP by coordinating with statisticians to write efficient, re-usable, and easily maintainable code that access, analyze and report data descriptives and analyses. The incumbent primarily uses SAS; additional statistical and analytical software programs are used as needed. Core to the role is the ability to communicate effectively, work collaboratively with colleagues and be responsive to the needs of both internal and external customers within an environment of mutual cooperation and respect. The Senior Statistical Programmer shows independence in management of workload and production of quality output, as well as technical expertise that contributes to the programmatic infrastructure of the Statistical Programming group.

Responsibilities

Responsibilities will include a subset of the following, based on network(s) supported:

  • Gather and document requirements for developing or modifying existing programs and systems
  • Define and edit mock tables, listings and figures (TLFs) and analysis dataset specifications
  • Generate, document, and maintain analysis datasets
  • Create ad hoc, standard and study-specific reports (e.g. SMC, DSMB, SMB); may perform cross-study reporting
  • Test and de-bug programs and maintain version control on production programs and scripts
  • Design and develop new work instructions (WIs) and updates to existing
  • May coordinate efforts to standardize WIs or processes across studies
  • Develop and maintain automation of routine analysis data and reporting tasks
  • Contribute to good programming practices, and cross-group programming initiatives and code libraries
  • Work with clinical programmers, labs, statisticians, and other statistical programmers to resolve data quality, processing, and analysis issues
  • Contribute to mentoring and training of junior Statistical Programmers and may supervise as needed

Qualifications

Required

  • Bachelor’s degree in Computer Science or a scientific, technical, or health-related field
  • At least four years of experience as a SAS programmer on PC/Unix platform; Preferred experience programming in support of clinical trials, statistical programming in a clinical research setting or other health research programming support
  • Demonstrated ability to communicate effectively in a matrix management environment as a member of several project teams
  • Demonstrated ability to multi-task and appropriately prioritize work assignments
  • Knowledge of and experience with clinical trials research data
  • Knowledge of and experience with biostatistics or statistical analyses in a clinical trials setting
  • Advanced SAS programming skills
  • Strong reporting and SAS macro development abilities
  • Knowledge of SAS (including graphics experience) and other programming languages
  • Ability to use Perl or other scripting languages for text manipulation and automated job control

 

Preferred

  • Graduate degree in computer science or a scientific, technical, or health-related field
  • Knowledge of CDISC standards (SDTM and ADaM)
  • Experience using version control tools

Senior Fellow, Infections in Immunocompromised Patients

FH Vaccine and Infectious Disease Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 15208

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   


The Hill Group in the Vaccine and Infectious Disease Division at the Fred Hutchinson Cancer Research Center is recruiting a Senior Fellow to conduct research on infections in immunocompromised patients. Dr. Hill and his research team are conducting multiple epidemiologic and translational studies of strategies to improve the diagnosis, treatment, and prevention of infections after CAR-T cell therapy, hematopoietic cell transplantation, and other immunosuppressive treatments.

Responsibilities

The responsibilities of this position will include leading independent and collaborative studies from start to finish, including study planning, obtaining regulatory approval, collecting and generating data, assisting with statistical analyses, and publication of results. In addition to investigator-initiated research, applicants with an M.D. may provide infectious disease consultation for cancer patients at the Seattle Cancer Care Alliance outpatient Transplant ID Clinic under the supervision of an attending ID physician. Additional opportunities include training in the conduct of industry-sponsored clinical trials and other opportunities to build research skills.     

Qualifications

We are seeking candidates with an M.D. or equivalent degree who have completed an accredited Infectious Diseases training program. Candidates should be highly motivated and capable of working independently in a team environment with strong writing, verbal communication, and problem-solving skills. Candidates with prior research training and a publication record are preferred.

Senior Statistical Programmer

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 19076

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

 



The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking a Senior Statistical Programmer. Under minimal supervisions, the Senior Statistical Programmer provides statistical programming expertise within SCHARP by coordinating with statisticians to write efficient, reusable, and easily maintainable code that access, analyze and report data descriptives and analyses. The incumbent primarily uses SAS and R; additional statistical and analytical software programs are used as needed. Core to the role is the ability to communicate effectively, work collaboratively with colleagues and be responsive to the needs of both internal and external customers within an environment of mutual cooperation and respect. The Senior Statistical Programmer works on complex assignments, shows independence in management of workload and production of quality output, as well as technical expertise that contributes to the programmatic infrastructure of the Statistical Programming group. The Senior Statistical Programmer may also mentor and/or supervise a junior statistical programmer.

Responsibilities

  • Gather and document requirements for developing or modifying existing programs and systems
  • Define and edit mock tables, listings and figures (TLFs) and analysis dataset specifications
  • Generate, document, and maintain analysis datasets
  • Create ad hoc, standard and study-specific reports (e.g. SMC, DSMB, SMB); may perform cross-study reporting
  • Test and de-bug programs and maintain version control on production programs and scripts
  • Design and develop new work instructions (WIs) and updates to existing WIs.
  • May coordinate efforts to standardize WIs or processes across studies
  • Develop and maintain automation of routine analysis data and reporting tasks
  • Contribute to mentoring and training of junior Statistical Programmers as needed

Qualifications

Required

  • Bachelor’s degree in computer science or a scientific, technical, or health-related field
  • At least five years of experience in SAS or R programming, with additional experience in other programming languages including a scripting language
  • At least two years of experience in support of clinical trials, in a clinical research setting or other health research setting;
  • Demonstrated ability to communicate effectively in a matrix management environment as a member of several project teams
  • Demonstrated ability to multi-task and appropriately prioritize work assignments
  • Knowledge of and experience with clinical trials research data
  • Knowledge of and experience with biostatistics or statistical analyses in a clinical trials setting
  • Knowledge of R (graphics experience) and other programming languages
  • Strong SAS reporting and macro development abilities
  • Advanced SAS programming skills
  • Ability to use Perl or other scripting languages for text manipulation and automated job control

 

Preferred

  • Graduate degree in computer science or a scientific, technical, or health-related field
  • 5+ years of statistical programming in a clinical research setting.
  • Knowledge of CDISC standardization practices
  • Knowledge of laboratory data

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Site Operations, Project Coordinator

FH Vaccine and Infectious Disease Division
Category: Administrative Support
Seattle, WA, US
Job ID: 19182

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


 

The HIV Vaccine Trials Network (HVTN) is the world’s largest publicly funded multi-disciplinary international collaboration facilitating the development of vaccines to prevent HIV/AIDS. Most recently, the COVID-19 Prevention Network (CoVPN) was formed by the National Institute of Allergy and Infectious Diseases (NIAID) at the US National Institutes of Health to respond to the global pandemic. Using the infectious disease expertise of their existing research networks and global partners, NIAID has directed the HVTN to utilize their experience and expertise to address the pressing need for vaccines and antibodies against the SARS-CoV-2 virus. The mission of CoVPN is to conduct Phase 3 Efficacy Trials to prevent infection and COVID-19 disease. CoVPN will work to develop and conduct studies to ensure rapid and thorough evaluation of United States government-sponsored COVID-19 vaccines and antibodies for the prevention of COVID-19 disease.


JOB SUMMARY
The Project Coordinator position will support the Site Operations Unit at the HVTN and CoVPN Leadership Operations Centers (LOC). The incumbent works under the direction of the Sr. Clinical Trial Manager. Special skills and knowledge are applied in coordinating research and administrative activities and in carrying out moderately complex clinical trials operations and research assignments.

Responsibilities

  • Work with all Clinical Trials Managers to maintain and assure adherence to major protocol milestones and study specific activities
  • Coordinate research and administrative activities with Clinical Trials Managers, ensuring all projects are completed according to project/study timelines
  • Organize and support study protocol/operations conference calls, e-mail communications, and meetings. Tasks to include polling and scheduling calls, distributing call announcements, agendas, and meeting materials, and taking/distributing minutes
  • Create and update protocol-specific distribution list (alias lists) to effectively and efficiently distribute study related written communications to network members
  • Create and update Microsoft Team sites including: adding and editing membership, document management, and responding to access issues as necessary
  • Assist with the management of the HVTN Manual of Operations (MOP). Tasks to include processing updates to over 70 MOP sections, maintaining electronic files containing the original, approved MOP sections, translating selected MOP sections into Portuguese and Spanish, maintaining version control and a spreadsheet of all sections, prompting section authors to update their sections annually, and notifying network members about new, revised, or translated MOP sections after posting them on the HVTN website
  • Participate in the development, review, production, and distribution of training materials for on-site training, study-specific procedures, and other study and network materials
  • Manage translations of study materials for non-US sites
  • Assist Clinical Trials Managers in documenting procedures and policies, and formatting study related special procedures and forms
  • Participate in working groups, special projects, workshops and trainings as needed; attend regular group and network meetings
  • Arranges multiple-day face-to-face protocol meetings both virtual and onsite; including inviting guests, validating travel requests, ordering catering, reserving meeting rooms and providing general support throughout the meeting as required
  • Perform other administrative tasks such as posting materials to internal/external web pages, updating study-related templates and documents, maintaining checklists, arranging logistics for training, and distributing participant ID cards etc.
  • Serve as a backup liaison with study site staff regarding protocol implementation and operational issues
  • Work with other LOC staff to improve cross-unit processes/systems and implement special projects
  • Performs other responsibilities as required

Qualifications

  • BA/BS desired or additional years of experience will subsitute for degree
  • 5+ years project coordination experience in a research setting or 3+ years post-master's degree
  • Position requires a high level of attention to detail and organization
  • Excellent written and verbal communication skills
  • Good interpersonal skills, and an ability to maintain confidentiality are essential
  • Must have demonstrated ability to work independently and take initiative in a dynamic environment
  • High level knowledge of Microsoft applications, specifically Word, Teams, Excel, and Outlook are required


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Software Development Engineer I/II

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18785

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The Gottardo Lab at Fred Hutch is a research lab within the computational biology program focused on creating statistical methods and software tools to analyze high throughput biological data. Our team works in collaboration with bench scientists and clinicians we work to understand severe diseases such HIV, malaria, and cancer and ultimately help develop vaccines and/or a cure. As a team, we value collaborative efforts, continued learning, and passion for our work.


Currently, the Gottardo Lab is working fully remote through at least summer 2021. You can learn more about the lab and lab members at rglab.org

 

The Software Development Engineer (SDE) will work primarily with the ImmuneSpace team to manage www.immunespace.org, a portal for immunologists to access and analyze public vaccine clinical trial data. As a team, the members of ImmuneSpace aim to craft quality code as we constantly improve our systems of DevOps, automated testing, and data visualization. Our goal is to produce high-quality features that meet scientists' needs using a collaborative workflow. As a member of the team, the SDE will take on a variety of tasks: refactoring react.js front-end data visualization components, writing custom SQL queries, managing infrastructure updates (e.g. apache tomcat), and updating an internal R API to perform analysis and serve results.

 

Our Culture:

  • Work in an organization that aims to make the world a better place and is home to three Nobel Prize winners
  • Enjoy an awesome work-life balance with a strong dedication from management to a 40 hour work week

Responsibilities

  • Maintain, modify and develop software features in JavaScript, R, and SQL
  • Contribute to the automated testing framework for both the web-based database portal and the R API client
  • Write and maintain user-facing and internal documentation.
  • Participate in feature requirements gathering, design and tasking for new development or refactoring.
  • Engage in code discussions and reviews to ensure all team-members are cross-trained on all parts of the larger codebase.

Qualifications

Minimum qualifications for SDE I:

  • Bachelor’s Degree or equivalent experience
  • 1+ years professional experience in software development
  • Interest in learning data engineering with R
  • Some experience with modern front-end JavaScript frameworks (e.g. React or Angular) and libraries (e.g. Bootstrap)
  • Detail oriented including the following:
    • Ability to understand a system of complex interactions and explain this understanding to technical and non-technical collaborators
    • Capable of deep troubleshooting to discover the root causes of problems
    • Has well-commented code and documentation
    • Positive attitude, willingness to ask questions and learn independently
  • Working knowledge of version control systems (e.g. git)


Minimum qualifications for SDE II:

  • Bachelor’s Degree or equivalent experience
  • 3+ years of experience working in software development
  • Some experience with SQL-based Relational Database Management Systems (e.g. PostGreSQL or MySQL), such as defining schema and writing custom queries
  • Some experience writing APIs, preferably in a data-centric application
  • Some front-end experience with a modern JavaScript framework
  • Experience with automated testing systems (e.g. TravisCI, CircleCI, Github Actions)
  • Experienced with version control systems and their use within an agile development setting
  • Working knowledge of software design patterns and principles

 

Preferred qualifications:

  • Experience working with medium-size datasets in a common data science language (e.g. R, Python, MatLab), including visualization
  • Comfortable in UNIX systems and working at the command line
  • Experience with cloud infrastructure (e.g. AWS / Azure) or containerization (Docker)
  • Basic knowledge of data science and statistics


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Software Development Engineer I/II - Bioinformatics Tools

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18394

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The Gottardo Lab at Fred Hutch is a research lab within the computational biology program focused on creating statistical methods and software tools to analyze high throughput biological data. Our team works in collaboration with bench scientists and clinicians we work to understand severe diseases such HIV, malaria, and cancer and ultimately help develop vaccines and/or a cure. As a team, we value collaborative efforts, continued learning, and passion for our work.


Currently, the Gottardo Lab is working fully remote through at least summer 2021. You can learn more about the lab and lab members at rglab.org


The Software Development Engineer I/II will help develop, implement and optimize computational data science software tools and analytic pipelines for clinical and non-clinical data sets, leveraging R. Within the Gottardo Lab we are building open source tools to enable analysis, integration, and sharing of large data sets in order to facilitating reproducible research. The candidate will work as part of a team to support data analysis and software development. The candidate is expected to adhere to good software development practices (e.g. design, unit tests, documentation, code review), and participate in regular team meetings. 

 

Our Commitment to Diversity

As a lab, we value inclusion and a diversity of backgrounds and perspectives to inform and improve our work. Given these values, we strive to make our recruitment and promotion processes transparent, fair, and supportive. Therefore, we strongly encourage all individuals with interest in the position to apply.

Responsibilities

  • Manage software refactoring and development to address user-raised issues in R-based packages 
  • Develop pipelines to support assay re-analysis  
  • Work within a team to assess development needs and contribute to code reviews 

Qualifications

Minimum Qualifications SDE I:

  • BSc in STEM field or equivalent experience
  • Knowledge of biological assay data (e.g. RNAseq, scRNAseq, flow cytometry, etc.) 
  • 1+ years in R, including familiarity with data wrangling and package development 
  • Working knowledge of Web stack, AWS / cloud computing 
  • Working knowledge of Software version control (e.g. git) 
  • Familiarity with Unix-like operating system environment 

Minimum Qualifications SDE II:

  • MSc in Bioinformatics, Data Science, Computer Science, Statistics or equivalent field or BSc with 3+ years’ experience also qualifies
  • 3+ years in R, including experience in data wrangling and package development
  • Working knowledge of Web stack, AWS / cloud computing
  • Working knowledge of Software version control (e.g. git )
  • Track record of contributions to open source software projects
  • Proficiency in Unix-like operating system environment

 

Preferred Qualifications

  • Experience with containerization, e.g. Docker
  • Experience with workflow languages and infrastructure-as-code, e.g. NextFlow
  • Excellent written and oral communication skills


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists. 

Sr. Project Manager - HVTN Endpoints

FH Vaccine and Infectious Disease Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 19175

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


 

The HIV Vaccine Trials Network (HVTN) Laboratory Center in the Immunology & Vaccine Development Program of the Vaccine & Infectious Disease Division is dedicated to understanding human immune responses and mechanisms of vaccine-induced immune protection against HIV, SARS-CoV-2 and other infectious diseases, such as malaria, Ebola and tuberculosis.


This position will be with the McElrath HVTN Laboratory in the Immunology & Vaccine Development Program within the Vaccine & Infectious Disease Division at Fred Hutch. The position is for a Senior Project Manager to supervise the HVTN Endpoints Laboratory, a good clinical laboratory practices (GCLP) laboratory performing detailed evaluation of T cell responses to candidate vaccines.  The laboratory’s focus is on clinical trials of HIV and SARS-CoV-2 vaccines as well as investigations of immune responses to HIV and SARS-CoV-2 (COVID-19) infections. The Sr. Project Manager will lead a technical team, design of experiments and collection of data. They will also assist with implementation of GCLP compliance and train technical staff.

Responsibilities

Reporting to the HVTN Laboratory Associate Director, the Sr. Project Manager will coordinate and carry out activities including but not limited to:

  • Lead immune assays, primarily focused on T cell responses: high-dimensional multiparameter flow cytometry, intracellular cytokine staining, viral inhibition assays, multiplexed cytokine detection assays (MSD/Luminex), and other assays as relevant.
  • Supervise, mentor, and train a team of research technicians
  • Oversee analysis of flow data and results
  • Coordinate with statistical groups and internal and external stakeholders
  • Participation in both formal and informal sharing of data amongst collaborating researchers
  • Assist with external progress reports, grant applications and scientific articles
  • Coordinate establishment of new techniques in the laboratory
  • Other duties and projects as assigned

Qualifications

  • Ph.D. or M.D. in immunology or a related field, or equivalent combination of relevant work and post-bachelor’s education experience (i.e. BA/BS with 10+ years work experience or MA/MS with 5+ years work experience) required.
  • Experience with human immunology and multiparameter flow cytometry and analysis is required
  • Excellent communication (oral and written) and problem-solving skills are required
  • Duties will require working in a team-oriented research environment and in serving in a collaborative and supervisory capacity. A strong background in collaborative team leadership, positive communication and project completion is preferred.
  • Motivation and adaptability are essential, as is a keen interest in the HIV vaccine field
  • Knowledge of human clinical trials and/or GCLP/GLP experience is required
  • Proficiency in the following computer programs is necessary: MS Office, Illustrator or other drawing program, Prism, JMP, Excel, R and/or SAS statistical analysis program, and FlowJo and/or other flow data analysis programs
  • Special qualifications: willingness to work with biohazardous (e.g., HIV-1) materials, required
  • Hours: Must be flexible, able to work some nights and weekends

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Staff Scientist

FH Vaccine and Infectious Disease Division
Category: Staff Scientist
Seattle, WA, US
Job ID: 18056

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

The Stamatatos Lab, investigates the development of protective antibody responses during viral infections, by employing advanced Immunological, Molecular, Structural and Bioinformatic tools. The information generated from these studies is used to design immunogens to elicit similar antibody responses by vaccination.


We are seeking a Staff Scientist to assist with the development, validation, and testing of novel protein immunogens against HIV-1 and SARS-CoV-2. The candidate will be involved in the design of such immunogens and in the characterization of the B cell and antibody responses elicited in diverse animal models. The candidate will work independently and may supervise research technicians and PostDocs as needed.

Qualifications

  • PhD in immunology, or a related field, and 2+ years relevant postdoctoral experience
  • Expertise in B cell immunology is highly desirable
  • Experience with multicolor flow cytometry panels (>10 colors) and/or FACS
  • Experience with molecular biology and biochemistry, protein purification, and the analysis of protein-protein interactions is preferred
  • Experience with next generation sequencing and analysis would be beneficial
  • The candidate should have a proven track record of publication and written communication skills
  • Must be independent, show initiative, willingness to take up new skills and responsibilities, and be a team player
  • Excellent attention to detail and the ability to work independently are essential to success in this position
  • The candidate must be self-motivated, able to multitask and to work within a very collaborative environment


Applicants must submit:

  • Biosketch and at least 3 references
  • Cover letter discussing your interest in this position including statement of research interests and career goals

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Staff Scientist - BBE

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 19040

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The Biostatistics, Bioinformatics and Epidemiology Program within the Vaccine and Infectious Disease Division of Fred Hutch is seeking a Staff Scientist to serve as Protocol Statistician in support of the HIV Prevention Trials Network (HPTN) protocols, collaborate with scientists within the HPTN and develop creative solutions to statistical issues that arise within the HPTN. The mission of the HPTN is to identify acceptable, feasible, safe, effective, and scalable interventions for HIV prevention that address the needs of populations at risk in the US and around the world.  Design strategies encompass both Phase 1-3 randomized trials for biomedical agents and implementation trials.


HIV disproportionately impacts the global South and racial and gender minorities in the US; current HPTN studies are based in southern Africa, MSM and transgender in the US, Latin America and Asia, and people who inject drugs in the US.  We welcome applications that recognize the impact of HIV on these communities.

Responsibilities

The Staff Scientist will contribute to the HPTN research agenda through independent and collaborative research. The incumbent may perform some or all of the following responsibilities:

  • Contribute to science for the prevention of HIV through independent and collaborative research resulting in presentations and publications.
  • Provide statistical leadership in protocol development, monitoring and reporting, including responsibility for data safety and monitoring reports.
  • Mentor masters-level statisticians as necessary.
  • Author and lead analyses based on protocol data, and contribute to the preparation of manuscripts
  • Contribute statistical methods development arising from problems in HPTN science
  • Maintain current knowledge of and contribute to advancements in the HIV prevention research field through participation in professional organizations, scientific conferences, reading industry journals, and publication of manuscripts
  • Perform other tasks as required

Qualifications

  • A successful candidate will have a Ph.D. or equivalent in biostatistics, epidemiology, or applied statistics is required. 
  • Experience working with geographically diverse collaborative groups within a clinical research environment preferred
  • Prior knowledge of clinical trials, infectious diseases (e.g. polio, TB, HIV, etc.), and implementation science preferred
  • Experience in both early- and late-phase clinical trials, and/or broad applied statistical methodological experience preferred


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Staff Scientist, Vaccine Development

FH Vaccine and Infectious Disease Division
Category: Staff Scientist
Seattle, WA, US
Job ID: 17923

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

Responsibilities

The McGuire Lab is seeking a Staff Scientist to assist with the development, validation, and testing of novel vaccine candidates aimed at preventing HIV-1. The candidate will perform and in-depth characterization of the B cell and antibody response to novel HIV-1 candidate vaccines, perform data analysis, prepare reports/manuscripts, and supervise lab staff and related activities.

 

Assignments will be project oriented where goals are long term, rather that experiment oriented. The candidate will work independently and supervise research technicians and assist graduate students as needed. May be required to help with SARS-CoV-2 work as needed.

Qualifications

  • PhD in immunology, or a related field and 2+ years relevant postdoctoral experience. Expertise in B cell immunology is highly desirable.
  • Experience with multicolor flow cytometry panels (>10 colors) and/or FACS. Experience with molecular biology and biochemistry, including PCR, cloning, protein purification, and the analysis of protein-protein interactions is preferred. Experience with next generation sequencing and analysis would be beneficial.
  • The candidate should have a proven track record of publication and written communication skills
  • Must be willing to work with pre-clinical animal models including non-human primates. Must be independent, show initiative, willingness to take up new skills and responsibilities, and be a team player.
  • Excellent attention to detail and the ability to work independently are essential to success in this position
  • The candidate must be self-motivated, able to multitask and to work within a very collaborative environment

Staff Scientist-Bioinformatics, Johnston Lab

FH Vaccine and Infectious Disease Division
Category: Staff Scientist
Seattle, WA, US
Job ID: 18782

Overview

Computational Staff Scientist — Microbial Genomic/Metagenomic/Epigenomic analyses

 

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



A Computational Staff Scientist position is available immediately in the Vaccine and Infectious Disease Division (VIDD) of the Fred Hutchinson Cancer Research Center (Fred Hutch), Seattle, WA. The successful applicant will work with Dr. Christopher D. Johnston (Johnston Laboratory)

Responsibilities

The successful applicant will work with Dr. Christopher D. Johnston to develop and support the growing computational and bioinformatics efforts within a research group focused on the human microbiome. Central responsibilities will include all aspects of analysis and management of multiple unique data sets -primarily associated with long-read sequencing technologies (PacBio) including large scale computational genomics of clinical microbial strain collections, patient tumor and tissue metagenomics, and microbial/eukaryote epigenetics. Additionally, statistical analysis of large datasets, integration of multiple data elements, and generation of figures to visualize microbiome data and results.

 

The scientist is expected to assist researchers with data analysis, write manuscripts, provide figures and analyses for grant proposals, and present research at scientific meetings.

 

In addition, dependent upon career trajectory the scientist will have the option to write independent grant applications in the bioinformatics and microbiome space.  

Qualifications

  • Applicants should have a PhD degree in computational biology, bioinformatics, computer science, applied mathematics, statistics/biostatistics, biomedical engineering, evolutionary/systems biology or other fields with strong quantitative training
  • Demonstrated experience in analysis of large-scale sequence data, and integrated analysis of genomic, transcriptomic, or epigenomic, data is expected
  • Experience in high performance computing, and cluster infrastructure support and usage will be highly beneficial. Deep knowledge of mathematics and statistical methods and proficiency using statistical analysis software such as R or Matlab
  • Experience with a general scripting language such as Python, Ruby, Perl, or bash
  • Experience working with metagenomics / epigenomic / other Next Generation Sequencing (NGS) data and the ability to write custom scripts to access databases, perform and evaluate quality control and analyze NGS data
  • Proficiency with data visualization tools (Spotfire, Tableau, R, Python)
  • Experience with an object-oriented language such as Java, C++ or C# and familiarity with standard software development best practices: source code control, unit testing, in-code documentation and automated build environments
  • Development experience in Linux and Windows environments
  • Background with molecular biology or immunology a plus
  • Candidate must demonstrate outstanding personal initiative and creativity in problem solving


Application instructions:

Please include a cover letter with your application, detailing your interest and suitability for this position.


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Staff Scientist-Synthetic Microbiology/Epigenomic engineering (dCas9), Johnston Lab

FH Vaccine and Infectious Disease Division
Category: Staff Scientist
Seattle, WA, US
Job ID: 18783

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



A Staff Scientist position is available immediately in the Vaccine and Infectious Disease Division (VIDD) of the Fred Hutchinson Cancer Research Center (Fred Hutch), Seattle, WA.

 

The Johnston Laboratory is an interdisciplinary and highly collaborative team of classically trained microbiologists, synthetic microbiologists, bioinformaticians and engineers. Using cutting edge technologies and methodologies, we seek to gain a deeper functional understanding of what bacteria are doing and how they are doing it. We then use that information to create novel therapeutics and engineer the next generation of microbe-based technologies for application in human medicine, synthetic microbiology and bioengineering.

Responsibilities

The successful applicant will work with Dr. Christopher D. Johnston to develop and support expanding synthetic microbiology and epigenome-editing efforts (prokaryote/eukaryote) focused on the human microbiome.

 

Central responsibilities will include: (i) the management and advancement of multiple ongoing wet-lab research projects - primarily associated with the application of state-of-the-art long-read sequencing technologies (PacBio/Oxford-nanopore) in the context of clinical metagenomics and methylation studies. (ii) Design/engineering/purification and validation of novel CRISPR-Cas/dCas9-effector systems for prokaryotes/eukaryotes. (iii) Continued adoption of novel synthetic biology methodologies/technologies for creative problem-solving during strain engineering across a wide range of bacterial species.

 

The scientist is expected to drive project design and experimental execution in the wet lab, provide figures and analyses for grant proposals, and present research at scientific meetings. Additionally, the drafting of manuscripts with the PI, relating to multiple ongoing projects and analysis of large in-house genomic datasets, will be a paramount responsibility.

 

In addition, dependent upon desired career trajectory the scientist will have the option to write independent grant applications within the microbiome space.  

Qualifications

  • Applicants should have a PhD degree in Genomics, Microbiology, Molecular biology, Bioengineering, or related field
  • Candidate must demonstrate outstanding personal initiative and creativity in problem solving, ideally relating to NGS sequencing (PacBio/Oxford nanopore), CRISPR-Cas/dCas9-effectors, epigenomic editing or methylation analyses in eukaryote or prokaryotes
  • Proven understanding and expertise in synthetic biology techniques (such as CRISPR-Cas / Transposon mutagenesis / Recombineering / Gene Editing Tools)
  • Excellent written and oral communication skills are required for manuscripts/grants preparation, public presentation, and collaboration with other researchers
  • Experience with a general scripting languages such as Python, Ruby, Perl, or bash, will be advantageous


Application instructions:
Please include a cover letter with your application, detailing your interest and suitability for this position

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

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