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35 Found open positions

Bioinformatics Analyst I-II, Computational Analyses of Microbial Genomic/Metagenomic/Epigenomic Data

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18060

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


 

The Johnston Laboratory in the Vaccine and Infectious Disease Division at the Fred Hutchinson Cancer Research Center is recruiting a highly motivated and creative Bioinformatics Analyst to analyze multiple unique data sets primarily associated with long-read sequencing technologies (PacBio) including large scale computational genomics of microbial genomes, patient tumor and tissue metagenomics, and microbial/eukaryote epigenetics.

 

The Johnston Laboratory is an interdisciplinary and highly collaborative team of classically trained microbiologists, synthetic microbiologists, bioinformaticians and engineers. Using cutting edge technologies and methodologies, we seek to gain a deeper functional understanding of what bacteria are doing and how they are doing it. We then use that information to create novel therapeutics and engineer the next generation of microbe-based technologies for application in human medicine, synthetic microbiology and bioengineering.

Responsibilities

The Bioinformatics Analyst will be responsible for working with our team to provide data analyses and visualizations of primarily microbial datasets (Genomic/Metagenomic/Epigenomic data). A successful candidate will have experience in data analysis, generating visualizations, writing analyses summaries and abstracts, and managing time across various projects with different collaborators. Responsibilities and essential job functions include but are not limited to the following:

  • Supports the maintenance of computational infrastructure and the flow of samples and information for large-scale studies.
  • Contributes to web-based bioinformatics and public and proprietary relational databases. Assists in the development and application of computational tools.
  • Interpret complex biological information, conduct statistical and genomic analysis.
  • Write custom scripts to access databases, perform and evaluate quality control and analyze Next Generation Sequencing (NGS) data.
  • Assist in the development and refinement of data analysis and integration methodology and pipelines.
  • Develop modular and reusable software for use in basic science research and genomic analysis in a cost-effective and efficient manner with limited instruction or guidance.
  • Engage in bioinformatics literature to ensure the availability of robust methods, resources, and data sources. Work with research collaborators to gather requirements and create processes and pipelines to meet their research goals
  • Candidate must demonstrate outstanding personal initiative and creativity in problem solving
  • Excellent written and oral communication skills are required for manuscripts/grants preparation, public presentation, and collaboration with other researchers

Qualifications

The successful candidate will be involved in multiple funded projects and work closely with bench scientists during project design, method development, and data acquisition; executing, improving, and developing informatics pipelines based on evaluation of computational tools and reference databases; and conducting and reporting data analysis using principles of good statistical scientific practice and reproducible research.

 

We are accepting applications for either a Bioinformatics Analyst Level I (min 0-2 years) or Level II (min 3-6 years).

 

Minimum Qualifications:

  • Bioinformatics Analyst I Education: BS degree in Biology, Statistics, Computer Science or equivalent education with 0-2 years of work experience with bioinformatics in relevant scientific domain
  • Bioinformatics Analyst II Education: BS degree in Biology, Statistics, Computer Science or equivalent education with 3-6 years of work experience with bioinformatics in relevant scientific domain
  • 2+ years of experience in software development, data engineering, data science, or related field with a track record of manipulating, processing, and extracting value from large datasets
  • Extensive experience working with at least one of the following datasets, e.g. whole genome analyses (assembly and annotation tools, Pangenomics), Metagenome analyses (community compositional assessment and comparisons), epigenome analysis (SMRTseq, ChipSeq, ATACseq - data pipelines)
  • Proficiency in, at least, one modern scripting or programming language (Python, R, Node, or C++)
  • Ability to learn new tools and content quickly and independently
  • Strong oral and communication skills


Desired Qualifications:

  • MS degree with 2+ years of work experience with bioinformatics in relevant scientific domain
  • Beneficial experience relative to this role:
  • Experience with workflow solutions (e.g. NextFlow, Airflow, Luigi, Cromwell)
  • Experience using source code management and CI/CD solutions (e.g., Git, GitHub, Jenkins, GitLabCI)
  • Experience with AWS services (e.g. EC2, S3, Batch, Lambda)
  • Experience with application container solutions (e.g. Docker, Singularity)

 

Application Instructions:

Applications will be considered commensurate with experience and track record of achievement. Please include a cover letter with your application, detailing your interest and suitability for this position.

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Bioinformatics Analyst II

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 17875

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.  


The Gottardo Lab at Fred Hutch is a research lab within the computational biology program focused on creating statistical methods and software tools to analyze high throughput biological data. In collaboration with bench scientists and clinicians we work to understand severe diseases such HIV, malaria, and cancer and ultimately help develop vaccines and/or a cure. You can learn more about the lab and lab members at http://rglab.org/

 

The Bioinformatics Analyst is responsible for working with our collaborators to provide data analyses and visualizations using our bioinformatics tools. The bioinformatics analyst position will work with a small team of bioinformatics specialists and developers to achieve our goal of using computational methods to understand complex diseases. A successful candidate will have experience in data cleaning, data analysis, generating visualizations, writing analyses summaries and abstracts, and managing time across various projects with different collaborators.

Responsibilities

Responsibilities and essential job functions include but are not limited to the following:

  • Work with research collaborators to gather requirements and create software processes and data analysis pipelines to meet their research goals
  • Provide statistical analysis, data summaries, and visualizations for use in collaborating projects
  • Participate in meetings and presentations with collaborating labs
  • Write abstracts and summaries around computational methods
  • Assist team with data management tasks such as data cleaning and data standardization

Qualifications

Minimum:

  • BS degree in Biology, Statistics, Computer Science or related
  • 3+ years of experience in software development, data engineering, data science, or related field with a track record of manipulating, processing, and extracting value from large datasets
  • Some professional experience cleaning and analyzing biological assay data, e.g. flow cytometry, CytOF, single-cell genomics
  • Proficiency in a modern programming language used in data science (e.g. R, Python, SAS, Matlab, Scala, Java, C++)
  • Ability to learn new tools and content quickly and independently
  • Strong oral and communication skills

 

Preferred:

  • Experience using source code management and CI/CD solutions (e.g., Git, GitHub, Jenkins, GitLabCI)
  • Experience doing reproducible analysis using tools like Rmarkdown or Jupyter notebooks
  • Experience with application container solutions (e.g. Docker, Singularity)
  • Experience with AWS services (e.g. EC2, S3, Batch, Lambda)
  • Experience with workflow solutions (e.g. NextFlow, Airflow, Luigi, Cromwell)

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Biostatistician II-III

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18368

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 

The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking a Statistical Research Associate level II-III.

Responsibilities

The Statistical Research Associate provides high intermediate-level statistical support in the planning, operations, monitoring, analytic, and exploratory stages of clinical trials and research. Job duties may include some or all of the following:

  • Collaborate with PhD statisticians/epidemiologists, SRAs, laboratory scientists, laboratory data managers, and other subject-matter experts to provide statistical support for clinical studies and research projects or laboratory data and analyses including statistical considerations and planning (power and sample size calculations), randomization lists, consultation, study data analyses, and written summaries and tables of results for use in study reports - for example, Data and Safety Monitoring Boards or other interim review meetings, scientific abstracts and manuscripts, and/or tables in support of a Clinical Study Report for submission
  • Contribute to and review study documents including protocol drafts, statistical analysis plans, case report forms, and other documents as required
  • Collaborate with data management and operations in the development of quality assurance procedures for on-going data collection, cleaning and analysis - such as establishing edit checks, or HIV endpoint verification
  • Participate in verification of standard reports prepared by programmers or other team members
  • Apply and adhere to CDISC data standards and guidelines where required in the production of analysis datasets and reports; assist in the production of supporting CDISC documentation for submissions (Define.xml, Reviewer’s Guides)
  • Generate written summaries for use in customized statistical lab reports
  • Participate in protocol team conference calls and meetings, organizational meetings, interim data review meetings, scientific meetings, regional meetings and internal team meetings as required
  • Maintain functional understanding of standard policies and procedures and complete required training in a timely manner; Contribute to the development and maintenance of standard procedures and related quality documents
  • Participate in internal project initiatives which may include developing new tools and processes, evaluating new statistical software packages, or exploring other value-added team activities
  • Represent SCHARP and the data analytics unit at professional meetings
  • Mentor or formally supervise more junior SRAs as required. Conduct performance reviews of direct reports
  • Perform other responsibilities as required

Qualifications

Minimum qualifications:

  • MS or PhD degree in Statistics or Biostatistics or related field with demonstrated work experience.
  • SRA II A minimum 2yrs of work experience is required.
  • SRA III 3 years of related work experience is required.
  • Proficiency with the SAS or R (as required by specific team/project)
  • Demonstrated knowledge of general statistical practice within clinical trials
  • Thorough understanding of statistical programming process and best practices
  • Functional understanding of GCP and regulatory requirements
  • Proven track record of collaboration with internal colleagues
  • Strong oral and written communication skills

 

Preferred qualifications:

  • 4+ years of relevant work experience
  • Demonstrated specialized knowledge of statistical practice within network specialization
  • Proven track record of collaboration with external collaborators

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Biostatistician III-IV

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18369

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.


The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking a Statistical Research Associate level III-IV.

Responsibilities

The Statistical Research Associate provides low advanced-level statistical support in the planning, operations, monitoring, analytic, and exploratory stages of clinical trials and research. Job duties may include some or all of the following:

  • Collaborate with PhD statisticians/epidemiologists, SRAs, laboratory scientists, laboratory data managers, and other subject-matter experts to provide statistical support for clinical studies and research projects or laboratory data and analyses including statistical considerations and planning (power and sample size calculations), randomization lists, consultation, study data analyses, and written summaries and tables of results for use in study reports - for example, Data and Safety Monitoring Boards or other interim review meetings, scientific abstracts and manuscripts, and/or tables in support of a Clinical Study Report for submission
  • Contribute to and review study documents including protocol drafts, statistical analysis plans, case report forms, and other documents as required
  • Collaborate with data management and operations in the development of quality assurance procedures for on-going data collection, cleaning and analysis - such as establishing edit checks, or HIV endpoint verification
  • Participate in verification of standard reports prepared by programmers or other team members
  • Apply and adhere to CDISC data standards and guidelines where required in the production of analysis datasets and reports; assist in the production of supporting CDISC documentation for submissions (Define.xml, Reviewer’s Guides)
  • Generate written summaries for use in customized statistical lab reports
  • Participate in protocol team conference calls and meetings, organizational meetings, interim data review meetings, scientific meetings, regional meetings and internal team meetings as required
  • Maintain functional understanding of standard policies and procedures and complete required training in a timely manner; Contribute to the development and maintenance of standard procedures and related quality documents
  • Participate in internal project initiatives which may include developing new tools and processes, evaluating new statistical software packages, or exploring other value-added team activities
  • Represent SCHARP and the data analytics unit at professional meetings
  • Mentor or formally supervise more junior SRAs as required. Conduct performance reviews of direct reports
  • Perform other responsibilities as required

Qualifications

Minimum qualifications:

  • MS or PhD degree in Statistics or Biostatistics or related field with demonstrated work experience
  • A minimum of 4 years of related work experience is required
  • High-level proficiency with the SAS or R (as required by specific team/project)
  • Demonstrated functional knowledge of general statistical practice within clinical trials
  • Thorough understanding of statistical programming process and best practices
  • Minimum of 1 year of experience in a senior, lead or management role
  • Minimum of 1 year of experience statistical project management
  • Strong oral and written communication skills
  • Strong organizational and multi-tasking skills
  • Functional understanding of GCP and regulatory requirements
  • Proven track record of collaboration with internal and external partners


Preferred qualifications:

  • 5+ years of relevant work experience
  • Demonstrated specialized knowledge of statistical practice within network specialization
  • Proven track record of collaboration with external collaborators
  • 2+ years of experience in a senior, lead or management role
  • 2+ years of experience in statistical project management
  • Functional understanding of network needs and objectives
  • Able to lead network-specific statistical tasks with minimal supervision


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Biostatistician III-IV

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18544

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.



The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking a Statistical Research Associate level III-IV.

Responsibilities

The Statistical Research Associate provides low advanced-level statistical support in the planning, operations, monitoring, analytic, and exploratory stages of clinical trials and research. Job duties may include some or all of the following:

  • Collaborate with PhD statisticians/epidemiologists, SRAs, laboratory scientists, laboratory data managers, and other subject-matter experts to provide statistical support for clinical studies and research projects or laboratory data and analyses including statistical considerations and planning (power and sample size calculations), randomization lists, consultation, study data analyses, and written summaries and tables of results for use in study reports - for example, Data and Safety Monitoring Boards or other interim review meetings, scientific abstracts and manuscripts, and/or tables in support of a Clinical Study Report for submission
  • Contribute to and review study documents including protocol drafts, statistical analysis plans, case report forms, and other documents as required
  • Collaborate with data management and operations in the development of quality assurance procedures for on-going data collection, cleaning and analysis - such as establishing edit checks, or HIV endpoint verification
  • Participate in verification of standard reports prepared by programmers or other team members
  • Apply and adhere to CDISC data standards and guidelines where required in the production of analysis datasets and reports; assist in the production of supporting CDISC documentation for submissions (Define.xml, Reviewer’s Guides)
  • Generate written summaries for use in customized statistical lab reports
  • Participate in protocol team conference calls and meetings, organizational meetings, interim data review meetings, scientific meetings, regional meetings and internal team meetings as required
  • Maintain functional understanding of standard policies and procedures and complete required training in a timely manner; Contribute to the development and maintenance of standard procedures and related quality documents
  • Participate in internal project initiatives which may include developing new tools and processes, evaluating new statistical software packages, or exploring other value-added team activities
  • Represent SCHARP and the data analytics unit at professional meetings
  • Mentor or formally supervise more junior SRAs as required. Conduct performance reviews of direct reports
  • Perform other responsibilities as required

Qualifications

MINIMUM QUALIFICATIONS:

  • MS or PhD degree in Statistics or Biostatistics or related field with demonstrated work experience
  • A minimum of 4 years of related work experience is required
  • High-level proficiency with the SAS or R (as required by specific team/project)
  • Demonstrated functional knowledge of general statistical practice within clinical trials
  • Thorough understanding of statistical programming process and best practices
  • Minimum of 1 year of experience in a senior, lead or management role
  • Minimum of 1 year of experience statistical project management
  • Strong oral and written communication skills
  • Strong organizational and multi-tasking skills
  • Functional understanding of GCP and regulatory requirements
  • Proven track record of collaboration with internal and external partners


PREFERRED QUALIFICATIONS:

  • 5+ years of relevant work experience
  • Demonstrated specialized knowledge of statistical practice within network specialization
  • Proven track record of collaboration with external collaborators
  • 2+ years of experience in a senior, lead or management role
  • 2+ years of experience in statistical project management
  • Functional understanding of network needs and objectives
  • Able to lead network-specific statistical tasks with minimal supervision


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Biostatistician III-IV

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18370

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.


The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking a Statistical Research Associate level III-IV.

Responsibilities

The Statistical Research Associate provides low advanced-level statistical support in the planning, operations, monitoring, analytic, and exploratory stages of clinical trials and research. Job duties may include some or all of the following:

  • Collaborate with PhD statisticians/epidemiologists, SRAs, laboratory scientists, laboratory data managers, and other subject-matter experts to provide statistical support for clinical studies and research projects or laboratory data and analyses including statistical considerations and planning (power and sample size calculations), randomization lists, consultation, study data analyses, and written summaries and tables of results for use in study reports - for example, Data and Safety Monitoring Boards or other interim review meetings, scientific abstracts and manuscripts, and/or tables in support of a Clinical Study Report for submission
  • Contribute to and review study documents including protocol drafts, statistical analysis plans, case report forms, and other documents as required
  • Collaborate with data management and operations in the development of quality assurance procedures for on-going data collection, cleaning and analysis - such as establishing edit checks, or HIV endpoint verification
  • Participate in verification of standard reports prepared by programmers or other team members
  • Apply and adhere to CDISC data standards and guidelines where required in the production of analysis datasets and reports; assist in the production of supporting CDISC documentation for submissions (Define.xml, Reviewer’s Guides)
  • Generate written summaries for use in customized statistical lab reports
  • Participate in protocol team conference calls and meetings, organizational meetings, interim data review meetings, scientific meetings, regional meetings and internal team meetings as required
  • Maintain functional understanding of standard policies and procedures and complete required training in a timely manner; Contribute to the development and maintenance of standard procedures and related quality documents
  • Participate in internal project initiatives which may include developing new tools and processes, evaluating new statistical software packages, or exploring other value-added team activities
  • Represent SCHARP and the data analytics unit at professional meetings
  • Mentor or formally supervise more junior SRAs as required. Conduct performance reviews of direct reports
  • Perform other responsibilities as required

Qualifications

Minimum qualifications

  • MS or PhD degree in Statistics or Biostatistics or related field with demonstrated work experience
  • A minimum of 4 years of related work experience is required
  • High-level proficiency with the SAS or R (as required by specific team/project)
  • Demonstrated functional knowledge of general statistical practice within clinical trials
  • Thorough understanding of statistical programming process and best practices
  • Minimum of 1 year of experience in a senior, lead or management role
  • Minimum of 1 year of experience statistical project management
  • Strong oral and written communication skills
  • Strong organizational and multi-tasking skills
  • Functional understanding of GCP and regulatory requirements
  • Proven track record of collaboration with internal and external partners


Preferred qualifications

  • 5+ years of relevant work experience
  • Demonstrated specialized knowledge of statistical practice within network specialization
  • Proven track record of collaboration with external collaborators
  • 2+ years of experience in a senior, lead or management role
  • 2+ years of experience in statistical project management
  • Functional understanding of network needs and objectives
  • Able to lead network-specific statistical tasks with minimal supervision


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Clinical QA Specialist, HVTN and CoVPN

FH Vaccine and Infectious Disease Division
Category: Quality
Seattle, WA, US
Job ID: 18631

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The HIV Vaccine Trials Network (HVTN) is the world’s largest publicly funded multi-disciplinary international collaboration facilitating the development of vaccines to prevent HIV/AIDS. Most recently, the COVID-19 Prevention Network (CoVPN) was formed by the National Institute of Allergy and Infectious Diseases (NIAID) at the US National Institutes of Health to respond to the global pandemic. Using the infectious disease expertise of their existing research networks and global partners, NIAID has directed the HVTN to utilize their experience and expertise to address the pressing need for vaccines and antibodies against the SARS-CoV-2 virus. The mission of CoVPN is to conduct Phase 3 Efficacy Trials to prevent infection and COVID-19 disease. CoVPN will work to develop and conduct studies to ensure rapid and thorough evaluation of United States government-sponsored COVID-19 vaccines and antibodies for the prevention of COVID-19 disease.


The Clinical Quality Assurance Specialist position will coordinate the HVTN/CoVPN’s Leadership Operations Center (LOC) Quality activities, which consists of maintaining all aspects of the quality program, ensuring compliance with industry guidelines and regulations, and overseeing the electronic Trial Master Files. The incumbent works under the direction of the HVTN/CoVPN Director of Quality & Regulatory Affairs with minimal direction.

Responsibilities

  • Oversees the development and implementation of the Quality Management System, including but not limited to:
    • promoting a quality culture across the LOC
    • providing guidance and assistance to LOC staff on various aspects of the quality program, such as quality control activities
    • creating, maintaining and implementing Standard Operating Procedures (SOPs)
    • monitoring staff SOP training progress
    • tracking risk assessment needs and implementing the risk management program
    • monitoring issues and implementing the corrective and preventive action (CAPA) program and system
    • facilitating vendor audits
    • implementing internal audits
    • providing support for external audits
    • facilitating document control activities
    • implementing debarment checks
    • ensuring that quality records remain inspection ready
  • Oversees the development and implementation of electronic Trial Master Files (eTMFs) in Veeva Vault, including but not limited to:
    • creating and maintaining eTMFs
    • supporting system validations
    • performing quality control activities and internal audits of eTMFs
    • facilitating and monitoring staff training progress for Veeva Vault
  • Document procedures using Work Practice Guidelines, Job Aids, and checklists so others may fill in if needed
  • Support the Director of Quality & Regulatory Affairs in ongoing LOC Lean activities
  • Perform other tasks as assigned, including those related to Regulatory Affairs

Qualifications

  • BA/BS required, plus 2 to 4 years quality experience. Four years of progressive experience in implementing quality systems may substitute educational requirement.
  • Sharp critical thinking skills
  • High level of attention to detail and organization
  • Excellent written and verbal communication skills
  • Knowledge of Veeva Vault is highly desired
  • Experience in Lean methodologies is highly desired
  • Experience in clinical research is preferred
  • Knowledge of SharePoint, Blueworks, and SmartSheet is preferred
  • Good interpersonal skills and an ability to maintain confidentiality are essential
  • Demonstrated ability to work independently and take initiative in a dynamic environment


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Clinical Research Coordinator I - J. Hill Group

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 18641

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The position will work directly with an Assistant Professor in the Infectious Disease Sciences Program in the Vaccine and Infectious Disease Division to provide support to the Principal Investigator and research staff in the development, implementation and management of his diverse research portfolio, including research studies and clinical trials.


The Clinical Research Coordinator (CRC) will be responsible for providing support on all aspects of research study and clinical trial development and implementation. Primary responsibilities of the CRC will include assistance with the planning, coordination, implementation, and close-out (e.g. presentation of data, manuscript writing) of industry-sponsored clinical trials, in addition to retrospective and prospective observational or investigator-initiated interventional studies. Additional responsibilities will include communicating with internal and external collaborators and supporting study personnel in the preparation of regulatory documentation and audits if applicable.


Under the supervision of the Assistant Professor, the CRC will manage a portfolio of clinical research projects and will be required to perform their responsibilities with a high level of independence within the scope of study protocol(s) and institutional guidelines. The position will include interaction with patients, physicians, researchers, and other clinical providers and support staff within and outside of the Fred Hutch/ Seattle Cancer Care Alliance (SCCA) / UW system including the SCCA Patient Care Services.

Responsibilities

  • Prepares study start-up documentation including FDA submissions, eligibility checklists, study-specific clinic orders and study calendars
  • Research, maintain, analyze, and abstract patient clinical trial data from pre-study background (e.g., previous diagnoses and treatments) through clinical trial participation and long-term follow-up
  • Ensures patient eligibility requirements for clinical trials are met, assists in patient enrollment, screens and registers patients on study
  • Understand and interact with departments and automated electronic medical record systems throughout Fred Hutch/SCCA/UW system to ensure timely and complete delivery of data
  • Track status of potential and active clinical trial participants
  • Create and maintain the study’s manual of operations and laboratory manual
  • Create and maintain a REDCap database or equivalent for collection of study data. Abstracts data from medical records to complete study-specific case report forms. Maintains shadow chart with source documents. Assists in the development of data acquisition forms and instructions for completion.
  • Schedules study related clinic procedures such as blood draws, infusions and treatment according to protocol requirements; coordinates with clinic staff to ensure proper documentation and timing of research-related procedures
  • Coordinate and support regularly scheduled Sponsor or institutional monitoring visits to ensure quality and completeness of data. Responds to all findings and implements corrective action as necessary.
  • Coordinate long-term follow-up evaluations and data collection with clinical trial participants, SCCA, and participants’ local physicians
  • Serve as a liaison and reference resource to Physicians, Investigators, other staff members, and other organizations with questions about data collection or protocol procedures and requirements
  • Coordinate special projects regarding data collection, analysis, output, and presentation
  • Ensures compliance with ongoing reporting requirements to the Food and Drug Administration, National Institutes of Health, Human Subjects Committee, Institutional Review Board, Pharmaceutical Companies, and other agencies, to include annual reports, study amendments, safety reports, and unanticipated problem/noncompliance reports

Qualifications

  • BA/BS in a life sciences field of study required
  • Applicant must have one to two years of research or related experience
  • Previous experience in oncology research and clinical data collection is preferred
  • This position requires excellent organizational skills, attention to detail, ability to problem solve and to prioritize multiple competing tasks in a dynamic environment
  • Collaborative focus is essential, as well as strong written and verbal communication skills, including computer skills
  • Ability to work in teams and independently, flexible hours at times in support of clinical trials and regulatory and related compliance

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Clinical Research Coordinator II - J. Hill Group

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 18273

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The position will work directly with an Assistant Professor in the Infectious Disease Sciences Program in the Vaccine and Infectious Disease Division to provide support to the Principal Investigator and research staff in the development, implementation and management of his diverse research portfolio, including research studies and clinical trials.


The Clinical Research Coordinator (CRC) will be responsible for providing support on all aspects of research study and clinical trial development and implementation. Primary responsibilities of the CRC will include assistance with the planning, coordination, implementation, and close-out (e.g. presentation of data, manuscript writing) of industry-sponsored clinical trials, in addition to retrospective and prospective observational or investigator-initiated interventional studies. Additional responsibilities will include communicating with internal and external collaborators and supporting study personnel in the preparation of regulatory documentation and audits if applicable.


Under the supervision of the Assistant Professor, the CRC will manage a portfolio of clinical research projects and will be required to perform their responsibilities with a high level of independence within the scope of study protocol(s) and institutional guidelines. The position will include interaction with patients, physicians, researchers, and other clinical providers and support staff within and outside of the Fred Hutch/ Seattle Cancer Care Alliance (SCCA) / UW system including the SCCA Patient Care Services.

Responsibilities

  • Assist the research manager with preparing start-up documentation including IRB documents, eligibility checklists, study procedures/SOPs, study-specific clinic orders and study calendars (if not completed by the Clinical Research Manager)
  • Screens and registers patients; ensures eligibility requirements are met
  • Ability to consent patients and assures consent forms are completed correctly and in entirety
  • Schedules study related clinic procedures such as blood draws, infusions and imaging according to protocol requirements; coordinates with clinic staff to ensure proper documentation and timing of research-related procedures
  • Perform review of medical charts using ORCA/MINDscape and enter data in REDCap, Excel or other study-related databases
  • Abstracts data from medical records to complete study-specific case-report form (CRFs) (electronic and/or paper) in timely and accurate manner; maintains shadow chart with source documents
  • Maintain study and specimen tracking and inventory records for biospecimens pulled from repository
  • Assemble study kits for clinical trials
  • Perform basic processing and banking of lab specimens and associated record keeping
  • Collaborates with study sponsor/consortium delegate to assist with study monitoring visits and responds to findings
  • Creates and maintains patient tracking tools; communicates status to investigators, management and relevant departments
  • Manages study documentation throughout study life cycle including IRB annual renewals, modifications, patient study charts and regulatory binder
  • Liaises with study sponsor, investigator(s), research manager and members of study team to communicate timelines, expectations and study status
  • Acts as a resource to physicians, investigators, other staff members, and other organizations regarding protocol procedures, data collection requirements and other study related operations
  • Keeps knowledge and skills current by completing mandated training and attending meetings with the study team and the Consortium, such as the monthly coordinator meeting, relevant lectures, faculty and administrative presentations, and other opportunities of interest
  • Perform other duties as assigned

Qualifications

  • Bachelor’s degree in scientific/medical field or equivalent experience/education. Minimum of three years post-bachlor's experience in clinical study/trials coordination or relateed field.
  • Clinical research related certification is preferred
  • Experience with industry-sponsored clinical trials and documentation of case report form (eCRF) in study electronic data capture (EDC) system
  • Ability to work in teams and independently, flexible hours at times in support of clinical trials and regulatory and related compliance
  • Strong attention to detail and project management skills and experience is required
  • Well-organized and ability to juggle numerous tasks, often with conflicting and competing deadlines
  • Strong written and verbal communication skills
  • Strong computer skills, including proficiency in the Office Suite, and experience working with excel and databases (preferably REDCap)
  • Knowledge of federal regulations and guidelines that govern clinical research, including GCP and human subjects research

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Clinical Trial Assistant/Program Assistant I - Infectious Disease Sciences

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 18387

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



This is a full-time position to assist study coordinators with scheduling clinical trial subject appointments, study kit preparation and data entry in addition to performing chart review for research trials in infectious diseases. This unique position will work under the direction of the Senior Clinical Research Manager and the Principal Investigator. The incumbent will perform functions requiring knowledge and skills specific to the program studies and to clinical research.

Responsibilities

  • Assist the study coordinator with scheduling appointments for subjects on clinical trials, sample tracking and preparing study kits for a large sample collection study
  • Perform review of medical charts using ORCA/Mindscape and enter data in REDCap, Microsoft Access, Excel or other study-related databases
  • Perform data entry for CRFs and review data prior to entering to ensure its credibility
  • Assemble study kits for clinical trials
  • Assist with basic processing and banking of lab specimens and associated record keeping
  • Assist with retrieving and transporting clinical blood specimens from the UW Medical Center and Seattle Cancer Care Alliance
  • May perform other duties as assigned on Covid and non-Covid research

Qualifications

Minimum qualifications:

  • BA/BS in a biological sciences field, or Medical Assistant with experience in chart review and scribing
  • Must be competent working with Office Suite, particularly with Excel and PowerPoint. It is expected that the incumbent will be familiar with extracting data from a database and with data filtering.
  • Strong written and verbal communication skills
  • Attention-to-detail is required for the position

 

Desired qualifications:

  • Previous experience working with patient medical charts
  • Previous work as a medical scribe or similar experience with medical terminology
  • Experience working with REDCap and Access databases


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Clinical Trials Physician, HVTN and CoVPN

FH Vaccine and Infectious Disease Division
Category: Staff Scientist
Seattle, WA, US
Job ID: 18401

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   


 

The HIV Vaccine Trials Network (HVTN) is the world’s largest publicly funded multi-disciplinary international collaboration facilitating the development of vaccines to prevent HIV/AIDS. The HVTN conducts all phases of clinical trials, from evaluating experimental vaccines for safety and immunogenicity to testing vaccine efficacy and is housed at the Fred Hutchinson Cancer Research Center (Fred Hutch). The COVID-19 Prevention Network (CoVPN) was formed by the National Institute of Allergy and Infectious Diseases (NIAID) at the US National Institutes of Health to respond to the global pandemic. Using the infectious disease expertise of their existing research networks and global partners, NIAID has directed the networks to address the pressing need for vaccines and monoclonal antibodies (mAbs) against SARS-CoV-2. 

 

The Clinical Trials Physician plays a key role in providing scientific and clinical oversight and project management for the development and implementation of HIV vaccine and monoclonal antibody trials. We are looking for a physician with active interest in early phase trials who will work with the NIH and other developers in translating preclinical to clinical development. Clinical trials physicians report directly to HVTN leadership. Some experience with early phase trials; knowledge of preclinical toxicity models is desirable but not mandatory.

Responsibilities

  1. In collaboration with Network Principal Investigators and CoVPN and HVTN leadership, provide scientific review and input into concept and protocol development
  2. Manage multidisciplinary teams and institutions organized around the development and implementation of HIV and SARS-CoV-2 vaccine and monoclonal antibody protocols
  3. Represent the Network in interactions with Principal Investigators, vaccine developers, and other vaccine research and public health organizations involved in HIV and SARS-CoV-2 vaccine discovery
  4. Contribute to a core capacity for review and summary of scientific literature and analysis related to key issues for trial design
  5. Manage timelines for protocol development and implementation, to assure timely start dates for clinical trials. This includes process development and manufacturing of novel products
  6. Participate in the review of safety data from all phases of vaccine and monoclonal antibody clinical trials; this includes providing clinical input into the design of clinical monitoring plans and serving as medical monitor for clinical trials
  7. Other duties as assigned

Qualifications

  • A physician (M.D. or equivalent degree) is required
  • Preference will be given to those applicants with experience in clinical trials and to those applicants with training in phase 1 or preclinical evaluations of vaccines or antibodies
  • Board certification in internal medicine, family practice, pediatrics, preventive medicine, or infectious disease is desirable
  • The ideal candidate should:
    • be highly organized
    • have exceptional written and verbal communication skills
    • have experience managing multidisciplinary teams
    • be able to handle challenging workloads and multiple concurrent projects
    • be proficient with standard business productivity software, including word processing, spreadsheet, presentation graphics, and database applications

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

HVTN Lab Supervisor

FH Vaccine and Infectious Disease Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 18271

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.


The HIV Vaccine Trials Network (HVTN) Laboratory Center in the Immunology & Vaccine Development Program of the Vaccine & Infectious Disease Division is dedicated to understanding human immune responses and mechanisms of vaccine-induced immune protection against HIV, SARS-CoV-2 and other infectious diseases, such as malaria, Ebola and tuberculosis.

Responsibilities

This position will be with the HVTN Laboratory Center in the Immunology & Vaccine Development Program within the Vaccine & Infectious Disease Division at Fred Hutch. The position will involve a supervisory role overseeing detailed evaluation of the immune responses to candidate HIV and SARS-CoV-2 vaccines in clinical trials as well as investigations of immune responses to HIV and SARS-CoV-2 (COVID-19) infections. It will also involve a supervisory role for a good clinical laboratory practices (GCLP) laboratory performing primarily cellular immune function assays. This individual will lead the development of assays and design of experiments to examine vaccine immunity and with collection and analysis of data. They will assist with implementation of laboratory QC procedures and records, assist with validation of assays for the GCLP laboratory and train technical staff. The incumbent will work in conjunction with the HVTN Laboratory Center GCLP and R&D teams to perform this job. They will develop techniques and design experiments to examine vaccine induced immunity, with a special emphasis on early innate immune responses, and will assist with collection and analysis of data.


Reporting to the HVTN Laboratory Senior Staff Scientist, coordinate and carry out the projects of the HVTN Laboratory Center activities with a focus on Endpoint analysis and R&D including but not limited to:

  • Lead immune assays, primarily focused on T cell responses: high-dimensional multiparameter flow cytometry, intracellular cytokine staining, viral inhibition assays, multiplexed cytokine detection assays (MSD/Luminex), and other assays as relevant.
  • Supervise, mentor, and train a team of research technicians.
  • Analysis of flow data and results.
  • Collaborate and coordinate with statistical groups and internal and external stakeholders.
  • Participation in both formal and informal sharing of data amongst collaborating researchers.
  • Assist with external progress reports and grant applications.
  • Preparation of scientific articles.
  • Coordinate establishment of new techniques in the laboratory.
  • Other duties and projects as assigned.

Qualifications

  • Ph.D. in immunology or a related field required, and experience in vaccines, infectious diseases, or human immunology
  • Experience with multiparameter flow cytometry and analysis is required
  • Special qualifications: willingness to work with biohazardous (e.g., HIV-1) materials, required
  • Excellent communication (oral and written) and problem-solving skills are required
  • Duties will require working in a team-oriented research environment and in serving in a collaborative and supervisory capacity. A strong background in collaborative team leadership, positive communication and project completion is preferred, with the ability to create and manage project schedules, including tasks, deliverables, milestones and schedules.
  • Motivation and adaptability are essential, as is a keen interest in the vaccine field
  • Knowledge of human clinical trials and/or GCLP/GLP experience is desired
  • Proficiency in the following computer programs is necessary: MS Office, Illustrator or other drawing program, Prism, JMP and/or SAS statistical analysis program, and FlowJo and/or other flow data analysis programs
  • Hours: Must be flexible, able to work some nights and weekends

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Laboratory Manager

FH Vaccine and Infectious Disease Division
Category: Laboratory Research Sciences
ZA-Cape Town
Job ID: 18165

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

Since 2001, Fred Hutch has led an array of distinctive research activities in partnership with colleagues in South Africa to accelerate the development of a preventive HIV vaccine and improve the diagnosis, prevention, and treatment of cancer and infectious diseases worldwide. In 2013, Fred Hutch opened the state-of-the-art Cape Town HVTN Immunology Laboratory to serve as a base for HIV vaccine trials in South Africa. The HIV Vaccine Trials Network, or HVTN, a Hutch-based international collaboration of scientists and educators, opened two major trials in 2016 to test strategies for preventing HIV infection, including a study of a candidate vaccine which, if shown to be at least 50 percent protective, could become the world’s first licensed HIV vaccine.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


 

The purpose of this position is to oversee the laboratory physical space and equipment. The Lab Manager oversees equipment maintenance and smooth functioning of the physical space and building facilities and to manage laboratory projects under the direction of the laboratory management. This position will work independently in performing daily responsibilities, referring issues on as necessary. Skills and knowledge will be applied in coordinating operational and administrative activities necessary to smooth functioning of a clinical research laboratory.

Responsibilities

Manage Lab Facilities and Equipment (30%)

  • Oversee the laboratory facilities, including specialized HVAC and electrical systems, the generator and UPS. Coordinate and oversee regular maintenance and repairs and troubleshoot problems with assistance from the off-site facilities company.
  • Oversee and manage the 24hr on-call system and handle queries from personnel when laboratory alarms are triggered. Attend to high-level emergencies 24/7, supported by the lab team.
  • Coordinate purchase and shipment/receipt of laboratory equipment to ensure laboratory is well- equipped at all times
  • Oversee and coordinate equipment maintenance, repairs, purchases and usage, troubleshooting equipment that is not performing
  • Formally document equipment maintenance, trends and other parameters to ensure functioning according to GCLP standards
  • Manage installation of new laboratory equipment, overseeing processes such as verification, qualification and validation
  • Monitor and maintain lab space and equipment, ensuring that current laboratory resource needs are met and future program resource needs are anticipated
  • Maintain good working relationships with key service providers that support the laboratory
  • Monitor and manage service level agreement compliance by service providers and ensure timely annual agreement renewals


Oversee Lab Inventory (20%)

  • Monitor lab reagents and consumables, insuring inventory systems are in place and kept up to date and accurate at all times
  • Obtain quotes and order lab reagents and consumables as needed
  • Assist with preparation of and adherence to lab budgets, performing cost analyses as needed


Repository Management (20%)

  • Oversee the specimen repository, ensuring detailed organization and proper storage of all clinical trial specimens according to GCLP guidelines
  • Ship, receive and handle specimens according to IATA and GCLP guidelines and using the lab LIMS systems
  • Train lab staff on proper specimen handling to maintain cold chain at all times
  • Supervise lab staff when receiving and accessing specimens


Laboratory Safety and GCLP Compliance (30%)

  • Address all Environmental Health & Safety issues and ensure laboratory compliance at all times
  • Review lab documentation, performing QC checks to ensure compliance
  • Draft new laboratory SOPs and edit and review existing laboratory SOPs, ensuring they are kept up- to date
  • Prepare files for audits and attend audits as requested, assisting in addressing any issues raised at the audits
  • Oversee documents required to satisfy regulatory requirements

Qualifications

Education, certification, qualifications and experience needed:

  • BTech, BA or BSc in a related field required, preferably Biomedical Technology or equivalent diploma (Clinical Pathology, Haematology, Microbiology or Immunology)
  • Minimum of ten years of experience in a routine or research laboratory setting; lab management experience
  • Familiarity with the function and troubleshooting many types of laboratory equipment
  • Experience working in a laboratory environment according to Good Clinical Laboratory Practices


Competencies / job specifications required to do the job:

  • Technologically-inclined with extensive knowledge of and experience troubleshooting lab equipment and systems
  • In-depth knowledge of quality assurance, quality control and best laboratory practices
  • Excellent attention to detail
  • Effective communication and interpersonal skills; works well in a team environment
  • Self-starter that works independently
  • Good time management and works within set deadlines
  • Flexible and adaptable to the changing needs of a dynamic environment with a desire to learn

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Learning Experience Designer

FH Vaccine and Infectious Disease Division
Category: Human Resources and Legal
Seattle, WA, US
Job ID: 18552

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.


The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking Learning Experience Designer.

 


 

The Learning Experience Designer is responsible for defining, creating and delivering clear and impactful learning curricula and content to SCHARP staff. This position will collaborate with managers and subject matter experts to develop learning experiences and materials that support onboarding, teach core position skills, and train SCHARP staff on processes and procedures. This position is also responsible for ongoing training program evaluation and maintenance.

Responsibilities

  • Work with SCHARP’s management team and subject matter experts to define and develop learning programs and curricula
  • Document learning requirements and objectives
  • Collaborate with subject matter experts to develop in-person, e-learning and self-paced learning curriculum and content, including:
    • Storyboarding and scripting
    • Creation of eLearning, video, instructor led content and support aids as needed leveraging existing materials where possible
    • Validate learning materials with subject matter experts
    • Deliver, administer, coordinate, and monitor the delivery of the learning curriculum
    • Conduct evaluations to identify learning success and areas of improvement
    • Administer assessments to determine employee learning needs
    • Coordinate equipment arrangements related to learning
    • Serve as Administrator for the department’s learning management platforms
    • Maintain systems, create user profiles, input training schedules, manage transcript reporting, etc.
  • Maintain curriculum materials and regularly review and update curriculum and content based on changing business needs, changing regulatory requirements and process/procedure changes
  • Provide guidance to staff developing their own training content and deliverables
  • Other related duties as assigned

Qualifications

MINIMUM QUALIFICATIONS

  • Bachelor's degree in related field
  • At least 5 years’ experience including instructional design, curriculum and/or course content development in a business setting
  • Demonstrated knowledge of best practices in adult education and online learning
  • Experience producing engaging and effective e-learning modules, classroom-based training, and learning aides
  • Knowledge of and experience with learning management systems
  • Experience with Articulate 360 (or similar tool), Microsoft Office Suite and Microsoft PowerPoint required
  • Excellent written and verbal communication skills
  • Ability to write content for different audiences and delivery models in a clear and concise way
  • Excellent problem-solving and troubleshooting skills
  • Able to establish effective working relationships with stakeholders across the organization
  • Must be able to work individually and within a team environment
  • Keen attention to detail and high level of accountability, self-starter

 

PREFERRED QUALIFICATIONS

  • Knowledge or experience in clinical trial research
  • Experienced with SharePoint site owner administration

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Post-Doctoral Research Fellow, HIV Vaccine Design & Testing

FH Vaccine and Infectious Disease Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 17924

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

Responsibilities

The McGuire Lab is seeking outstanding postdoctoral fellows to work on a project involving the validating and testing of novel vaccine candidates to elicit broadly neutralizing antibodies against HIV-1.  Responsibilities include: 

  • Design and execute prime-boost immunization regimens in a humanized murine model which will serve as a surrogate for human vaccine trials 
  • Perform endpoint analyses including antigen-specific B cell sorting and serum antibody binding and neutralization assays to gain a high-resolution understanding of the immune response to immunization. 
  • To complement this analysis the candidate will perform single B cell sorting of human PBMC samples ascertain the identity of antigen-reactive naive B cells.  
  • May be required to help with SARS-CoV-2 work as needed 

Qualifications

  • PhD in immunology, biochemistry, or a related field is required and expertise in B cell immunology is highly desirable
  • Experience with conducting in vitro studies with human peripheral blood samples preferred.
  • The candidate should have a strong molecular biology background as well.
  • Experience in multicolor flow cytometry preferred.
  • The candidate must be independent, show initiative, willingness to take up new skills and responsibilities, and be a team player
  • Excellent attention to detail and the ability to work independently are essential to success in this position, as are good communication and organizational skills
  • The candidate must be self-motivated, able to multitask and to work within a very collaborative environment

Post-Doctoral Research Fellow, Mathematical Modeler

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18234

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

A Postdoctoral Research Fellow position with focus on development, refinement, and utilization of different classes of epidemiological transmission models, is available in the Vaccine and Infectious Disease Division at the Fred Hutchinson Cancer Research Center. Applicant will be joining a dynamic multi-disciplinary group to work on methods for effective model configuration and calibration using data collected by the COVID-19 Prevention Trials Network (CoVPN) as a basis for the methodological work. Among the key objectives of the modeling work are improving the understanding of SARS-CoV-2 transmission and COVID-19 disease dynamics, informing effective public health strategies, and guiding rational development of new preventive interventions, including vaccination programs. The position will require a substantial amount of programming and computation, good organization and communication skills.

 

To find out more, please visit: HPTN Modelling Centre and COVID-19 Model

 

This is a full-time position with salary based on NIH scale + excellent benefits. This position will remain open until filled.

Qualifications

Suitable applicants should have a PhD or equivalent degree in statistics/biostatistics, applied mathematics, infectious disease epidemiology, population biology, theoretical ecology or a similarly quantitative discipline. Research experience in mathematical modeling of biological systems, including but not limited to modeling infectious disease transmission and population dynamics, and experience with reviewing/analyzing scientific literature is required.


Experience with Bayesian statistical methods of model calibration or longitudinal data analysis is desired.


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Post-Doctoral Research Fellow, Viral Immunology

FH Vaccine and Infectious Disease Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 17839

Overview

Fred Hutchinson Cancer Research Center, home to three Nobel laureates, is an independent, nonprofit research institute based in Seattle. Its interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Its Vaccine and Infectious Disease Division, which is home to more than 70 faculty members, was established to facilitate and enhance the Hutch's efforts in infectious disease prevention and vaccine development.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.  



The Stamatatos Lab, investigates the development of protective antibody responses during viral infections, with emphasis on HIV-1 and SARS-CoV-2, by employing advanced Immunological, Molecular and Bioinformatic tools. The information generated from these studies is used to design immunogens to elicit similar antibody responses by vaccination.

Responsibilities

We have two positions for Postdoctoral fellows interested in:

  • Investigating the development of B cell and antibody responses against SARS-CoV-2 in adult and pediatric patients
  • Investigating the activation and expansion of B cells that produce HIV-1 neutralizing antibodies in immunized humanize murine

Qualifications

  • A PhD in Immunology or Microbiology are preferred
  • Strong background on T and/or B cell immunity, is important
  • Ability to work independently within a very collaborative environment is critical, as are strong written, communication and organizational skills
  • Salary will be commensurate with appropriate experience

Applicants must submit:

  • Cover letter discussing your interest in this position including statement of research interests and career goals
  • Include a separate attachment of at least 3 references - Names and contact information

Post-Doctoral Research Fellow- Stamatatos Lab

FH Vaccine and Infectious Disease Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 18055

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. The Vaccine and Infectious Disease Division, which is home to more than 70 faculty members, was established to facilitate and enhance the Hutch's efforts in infectious disease prevention and vaccine development. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

The Stamatatos Lab, investigates the development of protective antibody responses during viral infections, with emphasis on HIV-1 and SARS-CoV-2, by employing advanced Immunological, Molecular and Bioinformatic tools. The information generated from these studies is used to design immunogens to elicit similar antibody responses by vaccination.

 

We have two positions for Postdoctoral fellows interested in: 1) Investigating the development of B cell and antibody responses against SARS-CoV-2 in adult and pediatric patients and 2) Investigating the activation and expansion of B cells that produce HIV-1 neutralizing antibodies in immunized humanize murine.

 

Salary will be commensurate with appropriate experience.

Qualifications

Minimum qualifications:

  • A PhD in Immunology or Microbiology are preferred.
  • Strong background on T and/or B cell immunity is preferred
  • Ability to work independently within a very collaborative environment is critical, as are strong written, communication and organizational skills

Applicants must submit:

  • Cover letter discussing your interest in this position
  • Curriculum Vitae
  • Statement of research interests and career goals
  • Names and contact information of at least three referees

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Postdoctoral Research Fellow, Bioengineering

FH Vaccine and Infectious Disease Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 18129

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

The Jia Zhu Lab has a post-doctoral position open to conduct research in immune responses in human barrier tissues.


The Postdoctoral Fellow recruited for this position will study the protective immune responses in human barrier tissue, such as skin and mucosa, against viral pathogens, including human herpes simplex virus. The candidate will participate in research activities:

  1. to expand the development of three-dimensional (3-D) ‘tissue organoids’ and/or ‘organ-on-chip’ platforms based on our new ‘skin-on-chip’ microfluidic device incorporated with a microvascular network, and
  2. to delineate viral-host interactions and understand monocytes, neutrophils and lymphocytes recruitment and function in human tissues using our in vitro tissue model system.
  3. to evaluate newly discovered antiviral drugs and compounds.

The candidate will conduct independent research and collaborate with a multidisciplinary team of researchers, engineers and clinicians, and be expected to conduct manuscript/grant writing and research presentations at local and major scientific conferences.

 

 

Qualifications

Minimum qualifications:

  • A Ph.D. in the field of Immunology, Virology or related fields and experience in a related area
  • Must be knowledgeable in modern molecular biology techniques and be proficient in microscopic imaging
  • The candidate should be highly motivated, with a strong desire to develop cutting edge technology
  • Be able to work independently in a team environment
  • Strong analytical skills, excellent written and verbal communication skills, and problem-solving skills are needed


Application instructions:

Please include a cover letter with your application, describing your research accomplishments as well as detailing your interest and suitability for this position.


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Principal Lab Programmer

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 13818

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

 

The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world.

Working here means never wondering if you are making a positive difference in the world. For the past 15 years, SCHARP has been be instrumental in eradicating diseases around the world. Recent work supporting COVID-19 studies affirms our continued importance to global health.

 

The Lab Programming team at SCHARP is looking for a lead programmer to join our team. We are a fun, egalitarian group that focuses on delivering reliable and reusable solutions.

Responsibilities

In this role, you will provide day-to-day technical leadership to an enthusiastic team of programmers; providing guidance on best practices, design, tools, and programming hygiene. This is not a management position - you will still get to be in the code most days.

 

An early project may include improving the requirements and specifications around our codebase. This will include working with the broader SCHARP Programming Unit to establish lightweight processes for validating python, 3rd party packages and our own in-house applications.

 

As a lead, you will advise on programming concepts and feasibility, as well as represent the Lab Programming team’s interests within the wider SCHARP environment.


Responsibilities may include:

  • Develop requirements and architecture for applications, processes and systems
  • Provide primary technical leadership and mentorship of a seven-person programming team
  • Design and implement data pipelines for laboratory assay data analysis
  • Development and maintenance of quality system documentation
  • Train users on application use, procedures, and data submission best practices
  • Troubleshoot and resolve lab programming-related issues
  • Take initiative and lead complex, cross-functional team projects
  • Lead team projects in best practices or process improvement
  • Develop, apply and train team in best programming practices

Qualifications

Required

  • Bachelor’s degree in Computer Science or similar technical degree
  • 7+ years of delivering applications in Python or any object-oriented programming language
  • 3+ years of experience designing and drafting requirements for applications
  • Proficiency using source code management tools (SVN)
  • Experience with relational databases (Postgres)
  • Proficient Linux user - including command line tools
  • Exemplary attention to detail: testing, meaningful comments, root cause analysis


Preferred

  • Experience designing and deploying applications using Django or Flask
  • Basic CI/CT experience (Jenkins)
  • Programming in multiple languages for a scientific or health related field
  • Python, JavaScript, Java, Perl, Unix shell, Go, C/C++
  • Knowledge of laboratory procedures for assays
  • Understanding of computerized systems validation
  • Programming support of clinical trials, statistical programming, or other scientific research

QA/QC Associate- HVTN Lab Operations

FH Vaccine and Infectious Disease Division
Category: Quality
Seattle, WA, US
Job ID: 18075

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 


 

The HIV Vaccine Trials Network (HVTN) Laboratory Center is part of an international collaboration of scientists and educators searching for effective and safe vaccines. The HVTN’s mission is to facilitate the process of testing preventive vaccines against HIV/AIDS and related infectious diseases. The organization conducts all phases of clinical trials from evaluating experimental vaccines for safety and the ability to stimulate immune responses through to testing vaccine efficacy. The Laboratory Center is responsible for carrying out the scientific agenda of the HVTN by conducting laboratory-based studies to evaluate the immunogenicity of investigational vaccines.

Responsibilities

The focus of responsibilities for the QA Associate II is to provide oversight, coordinate and facilitate clinical site specimen processing and clinical testing lab projects and programs for the HVTN Laboratory Operations Division. QA Associate I vs. II designation will be based on candidate’s qualifications and related experience.

 

The QA Associate will provide QA oversight to processing labs associated with HVTN clinical trials by:

  • Providing oversight for domestic and international network site labs for HVTN study preparation: providing site training, developing and communicating study-related lab practices and operations, and determining network lab equipment needs. The QA Associate will monitor Good Clinical Laboratory Practice compliance, workload, and other key quality indicators that may impact deliverables.
  • Providing input and support to other divisions within the HVTN and client protocol teams for specimen processing, storage and shipping, as well as clinical lab testing/methodologies.
  • Facilitating implementation of specimen management programs for study related specimens including data entry and electronic systems support.
  • Providing oversight for specimen processing and cryopreservation training and certification program.
  • Providing peripheral blood mononuclear cell (PBMC) External Quality Control program support including analysis, interpretation and reporting to sites.  Review adequacy of site response on EQC reports.
  • Create additional quality assurance programs for other specimen types.
  • Collaborating with other divisions within the HVTN to support network clinical trials and representing the HVTN Lab Center in interactions with stakeholders.
  • Providing network lab support and training through regular site visits, conference calls, or other appropriate media. Must be able to adapt communication styles based on targeted audience and topic.
  • Assisting site labs with implementation of individualized Quality Assurance plans and related QA systems, such as local document control and equipment maintenance programs.
  • Coordinating, participating in, and supporting the efforts of the HVTN Laboratory Program and performing additional activities as necessary.

Qualifications

Minimum qualifications

  • B.A./B.S. in a medical science field
  • Minimum 5 years of experience in clinical safety laboratory
  • Experience in Good Clinical Laboratory Practices (GCLP), clinical laboratory quality assurance
  • Demonstrated experience in clinical safety laboratory management
  • Ability to work with minimal supervision

 

Preferred qualifications

  • At least 5 years of experience as a medical laboratory scientist or equivalent strongly preferred
  • At least 1 year of laboratory experience focused in quality assurance
  • Understanding of HIV diagnostics testing
  • Demonstrated experience with PBMC (peripheral blood mononuclear cell) processing and storage and clinical trials
  • Computer skills – including Microsoft Word, Excel, PowerPoint and laboratory-specific programs
  • Good numeracy, literacy and organizational skills
  • Good interpersonal communication and time management skills
  • Willingness to be flexible in working hours, be willing to travel as needed, and work some evenings and weekends
  • Fluency in Spanish

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Regulatory Affairs Associate

FH Vaccine and Infectious Disease Division
Category: Clinical Research Support Services
Seattle, WA, US
Job ID: 18194

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center (Fred Hutch), home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first and largest cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.


The Vaccine and Infectious Disease Division (VIDD), one of five scientific divisions at Fred Hutch, addresses the growing need for treatment and prevention strategies for infectious diseases worldwide. VIDD is comprised of three research programs—Biostatistics, Bioinformatics & Epidemiology (BBE), Immunology & Vaccine Development (IVD), and Infectious Disease Sciences (IDS). The IVD Program is a large and diverse program, supporting the research of more than 20 faculty, more than 75 active grants and a research staff of more than 200. This program supports a complex portfolio of clinical trials in infectious diseases including HIV vaccine trials, COVID-19 vaccine trials, and related observational studies. The IVD Program currently has a vacancy for a Regulatory Affairs Associate.

Responsibilities

The Regulatory Affairs Associate is responsible for providing support and guidance to investigators on regulatory issues and requirements related to the conduct of clinical trials and use of investigational products. This role ensures proper oversight of clinical trials involving investigational new drugs (INDs). The Regulatory Affairs Associate serves as a liaison for PI(s)/study team and various internal/external regulatory oversight groups. This role is also responsible for coordinating submissions to local regulatory bodies including the Institutional Review Board (IRB) and Institutional Biosafety Committee (IBC) under the supervision of the Regulatory Affairs Manager.

 

Primary responsibilities:

  • Provide regulatory support to IVD Principal Investigators (PIs) working in multiple clinical trials units including the Vaccine Trials Unit (VTU), the Prevention Center (PC), the COVID Clinical Ressearch Center (CCRC) and other mobile locations
  • Write and prepare regulatory submissions including applications, renewals, amendments, consent forms, safety reports, study updates, etc. in accordance with required timelines
  • Prepare and coordinate site registration materials/submissions and assist with communications with sponsors and contract research organizations (CROs)
  • Assist in the development of project/study policies and procedures. Administer policies and procedures according to protocol, regulatory, and lab safety policies.
  • In partnership with the PI, prepare and track all clinical activity documents including IRB/IBC/site registration approvals, safety reports, deviations, laboratory certifications, staff training & licenses, monitoring notices and reports, inspections & compliance, etc.
  • Assist with sponsor monitoring visits remotely and onsite as needed
  • Create, maintain, and audit systems for tracking and implementing regulated activities at the clinical locations
  • Assure the proper management, retention, and version control of all applicable regulatory documentation including master files and amendments
  • Assist in the coordination of project activities to ensure they follow timelines and meet deadlines
  • Assist in the development of research materials
  • Perform information searches related to studies and projects
  • Provide clear and concise professional communication in response to reviewing bodies and regulatory agencies
  • Use judgment to interpret and apply federal and local regulations regarding clinical research
  • Perform other responsibilities as assigned

Qualifications

Required:

  • Bachelor’s degree
  • 3-5 years of experience working in regulatory affairs or related field
  • Previous experience in clinical trials regulatory operations with an emphasis on IND trials in a pharmaceutical, biotechnology, or academic clinical research setting
  • Experience preparing and reviewing regulatory applications, communicating with the regulatory committees, preparing for monitoring visits or audits, and assessing risk in the conduct of clinical research
  • Understanding and interpreting Good Clinical Practice and Human Subjects regulations
  • Excellent verbal and written communication skills
  • Highly organized, exhibit strong attention to detail and be able to manage multiple tasks and deadlines

Preferred:

  • Ability to work collaboratively
  • Successful candidate should be proficient in Microsoft Office Suite, Adobe, and Clinical Trials Management Systems
  • Able to work with minimal supervision and within a team environment
  • Regulatory Affairs, IRB Professional or Clinical Research certification

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Research Administrator III-IV - Infectious Disease Sciences Program

FH Vaccine and Infectious Disease Division
Category: Grants and Contracts
Seattle, WA, US
Job ID: 18636

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   


The Research Administrator III-IV position supports the fiscal management operations of the Infectious Disease Sciences (IDS) Program. The position collaborates with internal and external stakeholders and partners including Principal Investigators, program, division and center staff, and sponsor organizations to ensure timely and accurate accounting and financial reporting of sponsored research in compliance with federal and external sponsor regulations and requirements.

 

This position will co-manage the preparation, interpretation and analysis of financial data, and is responsible for the management and administration of sponsored and non-sponsored research project funds. (Pre and Post award management)

Responsibilities

The incumbent works with minimal supervision and reports to the Fiscal Manager in the Infectious Disease Sciences Program. The Research Administrator III-IV will design, develop, and be responsible for overseeing and managing budget/fiscal systems, policies, and procedures for grant and contract budgets for Principal Investigators and management staff. They are expected to use initiative and sound judgment in carrying out responsibilities within the framework of the appropriate funding source/agencies policies and procedures.

 

They provide highly responsive, efficient support services and has a broad range of responsibilities including: establishes and maintains comprehensive fiscal record keeping systems including: budget monitoring and reporting for grants management, subcontract oversight and special project support in support of the program.

 

This position serves as the liaison for funding issues related to grant, contract, subcontracts, clinical trial budget management and support with an increasing workload for these types of studies in IDS. In this area of responsibility, the RA interprets and ensures compliance with sponsor (federal and industry) guidelines and maintains and manages study payments and milestones.

  1. Develop and guide cost analysis process by establishing and enforcing policies and procedures; providing trends and forecasts; explaining processes and techniques; recommending actions to PIs and program leadership. Performs professional financial and budget analysis for PIs and program leadership promoting strategic decision-making and fiscal responsibility, using research business metrics to clarify all decision-making support optimal decision-making and cost management.
  2. Develop, modify, and maintain multiple record keeping and reporting systems for varied and complex sources of funding. Oversee and co-manage monthly budgets to actual reporting, year-end summary analysis and trend reporting to program leadership and PIs, and analysis of significant variances at a program and project level. Utilize online financial system to monitor budgets and resolve problems. Ensure accuracy and integrity of financial information in the development of complex technical fiscal analysis and financial reporting to multiple sources according to strict guidelines and deadlines. Review project costing classification and integrity of data used in financial reports, proposing resolutions of discrepancies in financial data to management, as needed.
  3. Assist in the annual budget process including analysis of submitted budgets compared to budget targets, preparation of summarization reports and communication of results to program leadership/PIs.


The position focuses on setting up of systems for industry-sponsored studies and working with Principle Investigators (PIs) and clinical research staff to maintain, monitor, track and manage study milestones and payments. Each clinical trial is unique as PIs work with a multitude of industry sponsors and each contract and study is unique based on enrollment criteria/eligibility, milestone tracking (e.g. patient visits, screen failures), complexity of reporting data, and close-out procedures.

  1. Manage/monitor sponsored and non-sponsored research projects funded with restricted contributions and communicate with program leadership/PIs for project approval and set-up, budget monitoring and project close-out. This includes: working closely with teams and sub-awarding institutions on managing sub award setup, billing and payments. Conduct all necessary steps in closing out of expired budgets including cost transfers, salary transfers, and verifying that all sponsor payments have been received.
  2. Oversee accounting for federal sponsored research grants, industry contracts, and other designated funds so that grants and contracts and non-sponsored research projects are managed in accordance with grantor and contractor requirements. Communicate with program leadership/PIs for project approval and set-up, budget monitoring and project close-out. This includes monitoring grant, contract, clinical trial, clinical research, foundation, operational, gift and discretionary budgets to document expenditures and verify proper accountability.
  3. Monitor non-sponsored research projects funded with restricted contributions and communicate with strategic planning initiative research administrators for project set-up, budgeting and close-out.
  4. Perform other financial analysis, grants management, and special projects as assigned.

Qualifications

  • Bachelor’s degree required, with a degree in accounting or finance preferred. 
  • Requirements for RA-III- Three years of of relevant work experience required.
    • Three or more years of grants administration in pre and post award, ideally in a research or not-for-profit environment highly preferred.
  • Requirements for RA-IV- Five years of relevant work experience required.
    • Five or more years of grants administration in pre and post award, ideally in a research or not-for-profit environment highly preferred.
  • Exceptional analytic skills and demonstrated ability to build financial models for business forecasting, variance analysis, and problem solving and providing recommendation based on results to PI and program management for strategic decision-making.
  • Advanced proficiency in Excel (including Pivot Tables), PowerPoint, Access, SharePoint and Word.
  • Experience with Tableau, or similar data visualization tool.
  • Well-developed verbal and written communication skills, including an ability to understand complex problems, to collaborate and explore alternative solutions. Ability to organize thoughts and ideas into understandable terminology.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Research Administrator III/IV

FH Vaccine and Infectious Disease Division
Category: Research Administration & Faculty Affairs
Seattle, WA, US
Job ID: 18041

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

 


 

The Biostatistics, Bioinformatics and Epidemiology (BBE) program housed within the Vaccine and Infectious Disease Division (VIDD) at Fred Hutch is seeking a Research Administrator III or IV. The Research Administrator will work independently and collaboratively to coordinate grant and contract proposals and renewal submissions; draft and process regulatory compliance documentation; monitor project budgets from pre-award to close-out; advise Principal Investigator(s) and Associate Director(s) of the current budget status and projections; ensure adherence to sponsor rules and regulations as well as Fred Hutch policies and guidelines; and interact with administrative personnel and external organizations regarding fiscal and regulatory aspects of the projects/program. They also participate in program, divisional or institutional improvement projects and problem resolution related to research administration. The position reports to the BBE Research Administration Manager.

Responsibilities

Pre-Award Activity:

  • Work closely with Principal Investigators (PIs) and other scientific staff to prepare and submit grant and contract applications to funding agencies
  • Advise faculty members as they navigate the grant proposal process on all parts of the application process and the different requirements of various funding sources
  • Develop the budget and related financial portions of the application or proposal while ensuring that content is accurate, complete, and in compliance with the governing regulations
  • Tracks the approval process to ensure that all necessary permissions are documented prior to the submission deadline
  • Identify sources for additional funding, supplements, and participate in business development activities as requested

 

Post-Award Activity:

  • Manage grants, contracts and research agreements awarded by a variety of funders including Federal agencies, private foundations and commercial enterprises in close collaboration with Principal Investigators (PIs) and program leadership
  • Ensure compliance with sponsor-specific reporting requirements, including tracking deadlines for progress reports, quarterly/annual financial reports and project closeouts
  • Plan for all competing and non-competing reports and renewals
  • Establish and monitor budgets and spending, ensuring compliance with regulations/guidelines
  • Proactively communicate about issues or concerns that may impact successful completion of the research
  • Prepare regular, relevant and timely reports for PIs and the BBE Program Operations Director regarding spending, headcount, and future projections
  • Monitor program employees’ effort and salary allocation; assisting PIs with monthly effort reporting
  • Serve as a liaison with administrative departments within Fred Hutch and at collaborating institutions
  • Partner with collaborating organizations on proposals, reporting, and budget management
  • Assist in the preparation and monitoring of Institutional Review Board (IRB) documentation and ensure regulations are followed for Human Subjects, Vertebrate Animals, and Hazardous Materials research
  • Participate as an active contributor in Continuous Improvement Projects
  • Serve as a divisional and/or program representative as needed

Qualifications

Required:

  • BA in Accounting, Finance, Public Administration, or related field. Relevant experience can substitute for educational requirement:
    • Research Administrator III minimum requirements: Three years in pre-award and post-award grants and contract management
    • Research Administrator IV minimum requirements: Five years in pre-award and post-award grants and contract management
  • Knowledge of relevant regulatory requirements related to IRB and IACUC compliance and ability to apply this knowledge
  • Effective and professional oral and written communication skills, with the ability to tailor communications to specific audiences
  • Ability to navigate complex internal systems and departments while exercising sound judgement and discretion
  • Proficient with complex budget development and use of reporting tools
  • Proficient in fiscal and budgetary management
  • Advanced skills in Word, Excel (including familiarity with pivot tables), Adobe Acrobat Pro, Outlook, and PowerPoint
  • Excellent time management and prioritization skills, with the ability to effectively manage multiple and competing demands
  • Demonstrated ability to function independently while exercising skill and informed professional judgment
  • Highly organized and detail oriented
  • Demonstrated ability to work successfully as part of a diverse team with a commitment to equity and inclusion


Preferred:

  • Experience working in a research organization, a university/medical school setting, or other complex non-profit organization
  • Experience with National Institute of Health (NIH) awards, namely Cooperative Agreements
  • Experience creating and using Tableau dashboards for reporting and analysis

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Research Project Manager I

FH Vaccine and Infectious Disease Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 18490

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The HIV Vaccine Trials Network (HVTN) Laboratory Center in the Immunology & Vaccine Development Program of the Vaccine & Infectious Disease Division is dedicated to understanding human immune responses and mechanisms of vaccine-induced immune protection against HIV, SARS-CoV-2 and other infectious diseases, such as malaria, Ebola and tuberculosis.

Responsibilities

This position will report to a Senior Staff Scientist in the McElrath HVTN Laboratory and will track the portfolio of active and upcoming research studies, coordinating with HVTN, laboratory and statistical colleagues. Job duties include: 

  • Set project goals and timetables, ensuring that all research and administrative activities are completed
  • Coordinate, plan and attend meetings, monitor activities to ensure objectives have been met within designated time frame, and coordinate follow-up activities
  • Serve as project/study liaison, representing the team to other Center departments, funding sources, affiliated individuals or institutions, and outside organizations
  • Coordinate grant/contract application process and associated progress reports, writing portions of progress reports as required 
  • Develop and monitor project/study budget, ensuring that all financial allocations and expenditures are in accordance with grant/contract guidelines and requirements
  • Coordinate space and equipment planning and utilization, evaluating current project/study needs, overseeing the acquisition of space and equipment, anticipating and planing for future needs
  • Assist the investigator(s) in the design of project/study methods such as study subject selection and retention, data collection, and database management
  • When applicable, coordinate the submission of study results and manuscripts for publication
  • Performs other responsibilities as required

Qualifications

  • BA/BS in related field required, MA/MS/MPH preferred
  • Minimum of 5 years of research management or laboratory experience 
  • High level of attention to detail, organizational skills and a commitment to accuracy
  • Advanced interpersonal, oral and written communication skills. Must demonstrate highly collaborative and communicative style as well as relationship building across multiple stakeholders.
  • The ability to create and manage project schedules, including tasks, deliverables, milestones and schedules
  • Proficiency in MS Office, Illustrator or other drawing program, JMP or Excel, and Microsoft Project or Smartsheet is highly desired

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Research Technician I

FH Vaccine and Infectious Disease Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 18681

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



This research opportunity is with the HIV Vaccine Trials Network (HVTN). The technician will perform experiments to identify and characterize immune responses at sites of HIV entry in participants who are part clinical trials. The incumbent will be responsible for processing blood or other body fluids and tissues from volunteers, performing the immunological assays, molecular biology assays and analyzing the data. They will assist in the development and maintenance of laboratory quality control (QC) methods and records. They will interpret and report on experimental results and may assist with data presentation for conferences and manuscripts.

Responsibilities

  • Perform and analyze molecular biology experiments, such as RNA isolations, DNA isolations, and real-time PCR quantitation
  • Conduct immunohistochemistry experiments, including immunohistochemistry staining, laser dissection microscopy, imaging and analysis of the slides
  • Perform in vitro cell manipulations, sterile culture and HIV infections of mucosal samples
  • Prepare tissue lysates and secretion eluates for protein quantitation experiments
  • Perform ELISA,  MSD and Singulex assays for evaluating antibodies, chemokines and cytokines in human secretions and tissue lysates
  • Maintain chain of custody for samples used in the laboratory
  • Develop and trouble-shoot new assays as needed
  • Analyze and present data
  • Maintain a high level of accuracy for all work
  • Maintain records for experiments and quality control for the laboratory
  • Prepare and maintain reagents, stocks, and cultures necessary to perform the work
  • Operate and carry out basic maintenance and QC of laboratory equipment
  • Perform other duties as assigned

Qualifications

  • A BA/BS with related laboratory experience in immunology, microbiology, molecular biology or similar field
  • Experience with molecular biology or immunology
  • Willingness and ability to work with blood, human tissues, human secretions, samples from COVID-19 infected subjects and HIV virus
  • Must be self-motivated, organized and be able to work within a team
  • Ability to be punctual and accurate
  • Excellent oral and written communication skills


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Research Technician I-II

FH Vaccine and Infectious Disease Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 17727

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

 

RESEARCH TECHNICIAN I/II- McElrath Laboratory                               

This research opportunity is with the McElrath laboratory, HIV Vaccine Trials Network (HVTN) and Coronavirus Prevention Network (CoVPN).  Our lab is recruiting a research technician to primarily perform assays to characterize antiviral T and B-cell responses.   S/he will be expected to perform complex research assays, utilizing flow cytometry to evaluate vaccine-induced cellular immune responses in vaccine recipients participating in clinical trials of investigational vaccines for SARS-CoV-2/COVID-19, HIV, malaria, tuberculosis (MTB), and Ebola.  S/he will be responsible for performing and coordinating the assays with other technicians and analyzing the data.  S/he will interpret and report on experimental results and assist with data presentation. S/he will assist in writing laboratory SOPs, reports, and other documentation. S/he will report to a project manager and work closely with a technical team.

 

The HVTN’s mission is to facilitate the process of testing preventive vaccines against HIV/AIDS or other infectious diseases. The organization conducts all phases of clinical trials from evaluating experimental vaccines for safety and the ability to stimulate immune responses through to testing vaccine efficacy. The HVTN laboratory is responsible for conducting laboratory-based studies to evaluate the immunogenicity of investigational vaccines.

 

Responsibilities

  • Maintain a high level of accuracy for all work.
  • Work well as team-member, participate in positive communication, and foster an environment that allows all laboratory staff to work well together.
  • Independently perform flow cytometry, FACS sorting, and other experimental assays, such as MSD, ELISpot and ELISAs.
  • Perform flow cytometry (intracellular cytokine staining and FACS sorting), ELISPOT and MSD/Luminex/ELISAs for characterization and monitoring of T and B cell responses.
  • Proactively prepare reagents for experiments and for general lab use.
  • Troubleshoot and optimize experimental methods, results and analysis.
  • Maintain accurate documentation for experiments and quality control for the laboratory.
  • Carry out maintenance, trouble-shooting and QC of laboratory equipment.
  • Review the literature to stay informed on the HIV vaccine field or immunological assays.
  • May perform data analysis, interpretation, and statistical analyses.
  • Other duties as assigned.

Qualifications

  • A bachelor’s degree in immunology or biological science
  • 2 years of laboratory experience. 
    • Research Techn I minimum qualifications- BA/BS in a scientific field required. Must have scientific knowledge in the area of study and basic laboratory skills.  Independent research experience in addition to school lab experience is usually necessary.
    • Research Techn II minimum qualifications- Intermediate level position requires a BA/BS and 2+ years’ experience working in a laboratory. Independent research experience outside of laboratory course work is required.
  • Specific experience with flow cytometry, immunology, cellular assays, and tissue culture are preferred. 
  • Motivation, adaptability and ability to be a strong team player are essential, as is a keen interest in the HIV vaccine field.
  • The candidate must be someone with great attention to details, well-organized, self-motivated, and able to efficiently manage time and experiments. 
  • Experience in a GLP or GCLP setting or clinical experience, with strong documentation skills is also desirable. Applicants must be willing to work with biohazardous/infectious agents (e.g., bloodborne pathogens, including HIV-1) and also be flexible and willing to work some evenings and weekends. Salary will be commensurate with appropriate experience. 

Research Technician III

FH Vaccine and Infectious Disease Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 18095

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



This research opportunity is with the McElrath laboratory and the HIV Vaccine Trials Network (HVTN). Our lab is recruiting an entry-level or experienced research technician to perform complex research assays to characterize primarily T-cell responses utilizing flow cytometry induced by investigational vaccines or during infection with SARS-CoV-2, HIV and other pathogens, such as malaria and TB. They will be responsible for standardizing and performing novel assays, and collecting and analyzing the data. They will interpret and report on experimental results and assist with data presentation. They will assist in writing laboratory SOPs, reports, and other documentation. The technician will report to a manager and work closely with a technical team.


The HVTN’s mission is to facilitate the process of testing preventive vaccines against HIV/AIDS or other infectious diseases. The organization conducts all phases of clinical trials from evaluating experimental vaccines for safety and the ability to stimulate immune responses through to testing vaccine efficacy. The HVTN laboratory is responsible for conducting laboratory-based studies to evaluate the immunogenicity of investigational vaccines.

Responsibilities

  • Maintain a high level of accuracy for all work
  • Work well as team-member, participate in positive communication, and foster an environment that allows all laboratory staff to work well together
  • Independently perform immunological, flow cytometry and other experimental assays
  • Troubleshoot and optimize experimental methods, results and analysis
  • Lead, train or coordinate other technicians, or team members on laboratory techniques and assays
  • Review the literature to learn and trouble-shoot new methods and stay informed on the HIV/SARS-CoV-2 vaccines and immunology
  • Prepare and present written or oral progress reports concerning studies including assembly, organization, and interpretation of data
  • Maintain accurate documentation for experiments and quality control for the laboratory
  • Supervise and carry out maintenance, and troubleshooting and QC of laboratory equipment
  • May perform data analysis, interpretation, and statistical analyses
  • Other duties as assigned

Qualifications

  • Senior level position requires a BA/BS and 4+ years’ relevant experience working in a laboratory, or a Master’s degree and an equivalent experience. Requires independent research experience with immunological assays and training and supervision of other staff
  • Experience with immunology, flow cytometry, COVID, HIV/AIDS and/or cellular assays are strongly desired
  • Motivation, adaptability and ability to be a strong team player are essential, as is a keen interest in the SARS-CoV-2/COVID-19 & HIV vaccine field
  • The candidate must be someone with great attention to details, well-organized, self-motivated, and able to efficiently manage time and experiments. Experience in a GLP or GCLP setting or clinical experience, with strong documentation skills is also desirable
  • Applicants must be willing to work with biohazardous/infectious agents (e.g., bloodborne pathogens, including SARS-CoV-2 & HIV-1) and also be flexible and willing to work some evenings and weekends
  • Salary will be commensurate with (appropriate) experience

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

SAS Statistical Programmer III

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 13941

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. The Center’s five scientific divisions collaborate to form a unique environment for conducting basic and applied science. Vaccine and Infectious Diseases Division (VIDD) works to eliminate or minimize the impact of globally significant infectious diseases. Within VIDD is the Statistical Center for HIV/AIDS Research & Prevention (SCHARP), which provides statistical support and data management to researchers worldwide in the fight against HIV/AIDS with active studies in the U.S., Africa, Latin America, Asia and Europe. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   


The Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at Fred Hutch is a full service statistical and data management center focused on HIV prevention research. SCHARP has an annual budget of over $40 million, more than 180 employees and is currently managing over 40 active phase I – III clinical trials in over 150 clinical sites around the world. SCHARP is seeking a Statistical Programmer III.

 

With guidance, the Senior Statistical Programmer provides statistical programming expertise within SCHARP by coordinating with statisticians to write efficient, re-usable, and easily maintainable code that access, analyze and report data descriptives and analyses. The incumbent primarily uses SAS; additional statistical and analytical software programs are used as needed. Core to the role is the ability to communicate effectively, work collaboratively with colleagues and be responsive to the needs of both internal and external customers within an environment of mutual cooperation and respect. The Senior Statistical Programmer shows independence in management of workload and production of quality output, as well as technical expertise that contributes to the programmatic infrastructure of the Statistical Programming group.

Responsibilities

Responsibilities will include a subset of the following, based on network(s) supported:

  • Gather and document requirements for developing or modifying existing programs and systems
  • Define and edit mock tables, listings and figures (TLFs) and analysis dataset specifications
  • Generate, document, and maintain analysis datasets
  • Create ad hoc, standard and study-specific reports (e.g. SMC, DSMB, SMB); may perform cross-study reporting
  • Test and de-bug programs and maintain version control on production programs and scripts
  • Design and develop new work instructions (WIs) and updates to existing
  • May coordinate efforts to standardize WIs or processes across studies
  • Develop and maintain automation of routine analysis data and reporting tasks
  • Contribute to good programming practices, and cross-group programming initiatives and code libraries
  • Work with clinical programmers, labs, statisticians, and other statistical programmers to resolve data quality, processing, and analysis issues
  • Contribute to mentoring and training of junior Statistical Programmers and may supervise as needed

Qualifications

Required

  • Bachelor’s degree in Computer Science or a scientific, technical, or health-related field
  • At least four years of experience as a SAS programmer on PC/Unix platform; Preferred experience programming in support of clinical trials, statistical programming in a clinical research setting or other health research programming support
  • Demonstrated ability to communicate effectively in a matrix management environment as a member of several project teams
  • Demonstrated ability to multi-task and appropriately prioritize work assignments
  • Knowledge of and experience with clinical trials research data
  • Knowledge of and experience with biostatistics or statistical analyses in a clinical trials setting
  • Advanced SAS programming skills
  • Strong reporting and SAS macro development abilities
  • Knowledge of SAS (including graphics experience) and other programming languages
  • Ability to use Perl or other scripting languages for text manipulation and automated job control

 

Preferred

  • Graduate degree in computer science or a scientific, technical, or health-related field
  • Knowledge of CDISC standards (SDTM and ADaM)
  • Experience using version control tools

Senior Fellow, Infections in Immunocompromised Patients

FH Vaccine and Infectious Disease Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 15208

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   


The Hill Group in the Vaccine and Infectious Disease Division at the Fred Hutchinson Cancer Research Center is recruiting a Senior Fellow to conduct research on infections in immunocompromised patients. Dr. Hill and his research team are conducting multiple epidemiologic and translational studies of strategies to improve the diagnosis, treatment, and prevention of infections after CAR-T cell therapy, hematopoietic cell transplantation, and other immunosuppressive treatments.

Responsibilities

The responsibilities of this position will include leading independent and collaborative studies from start to finish, including study planning, obtaining regulatory approval, collecting and generating data, assisting with statistical analyses, and publication of results. In addition to investigator-initiated research, applicants with an M.D. may provide infectious disease consultation for cancer patients at the Seattle Cancer Care Alliance outpatient Transplant ID Clinic under the supervision of an attending ID physician. Additional opportunities include training in the conduct of industry-sponsored clinical trials and other opportunities to build research skills.     

Qualifications

We are seeking candidates with an M.D. or equivalent degree who have completed an accredited Infectious Diseases training program. Candidates should be highly motivated and capable of working independently in a team environment with strong writing, verbal communication, and problem-solving skills. Candidates with prior research training and a publication record are preferred.

Software Development Engineer I (Front-End & Data Engineering)

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18396

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.


 

The Gottardo Lab at Fred Hutch is a research lab within the computational biology program focused on creating statistical methods and software tools to analyze high throughput biological data. Our team works in collaboration with bench scientists and clinicians we work to understand severe diseases such HIV, malaria, and cancer and ultimately help develop vaccines and/or a cure. As a team, we value collaborative efforts, continued learning, and passion for our work.  

 

Currently, the Gottardo Lab is working fully remote through at least summer 2021. You can learn more about the lab and lab members at http://rglab.org/ 

 

Lab Culture 

Work in an organization that aims to make the world a better place and is home to three Nobel Prize winners. 
Enjoy an awesome work-life balance with a strong dedication from management to a 40 hour work week 
When we return to in-office work, support for public transit / bike commuting, healthy eating options in the Hutch's cafes and an office across from the water in South Lake Union. 
Benefits include paid vacation, holidays, sick time, medical, dental and vision benefits as well as 403 (b) retirement plan. 
 

Lab's Commitment to Diversity

As a lab, we value inclusion and a diversity of backgrounds and perspectives to inform and improve our work. Given these values, we strive to make our recruitment and promotion processes transparent, fair, and supportive. Therefore, we strongly encourage all individuals with interest in the position to apply.

Responsibilities

The Software Development Engineer (SDE) will work primarily with the ImmuneSpace team to manage www.immunespace.org, a portal for immunologists to access and analyze public vaccine clinical trial data.  As a team, the members of ImmuneSpace aim to craft quality code as we constantly improve our systems of DevOps, automated testing, and data visualization. Our goal is to produce high-quality features that meet scientists' needs using a collaborative workflow.  As a junior member of the team, the SDE will take on a variety of tasks, including refactoring and developing front-end analytical features implemented in React.js as well as putting together and curating datasets for public consumption. 

  • Maintain, modify and develop software features in JavaScript, R, and SQL, such as updating React.js components, refactoring an R package, or creating custom SQL queries. 
  • Contribute to the automated testing framework for both the web-based database portal and the R API client 
  • Write and maintain user-facing and internal documentation. 
  • Participate in feature requirements gathering, design and tasking for new development or refactoring. 
  • Engage in code discussions and reviews to ensure all team-members are cross-trained on all parts of the larger codebase. 

Qualifications

  • Bachelor’s Degree or equivalent experience
  • 0-2 years professional experience in software development 
  • Experience with modern front-end JavaScript frameworks (e.g. React or Angular) and libraries (e.g. Bootstrap) and interest in learning data engineering with R 
  • Detail oriented including the following:  Ability to understand a system of complex interactions and explain this understanding to technical and non-technical collaborators 
  • Capable of deep troubleshooting to discover the root causes of problems 
  • Has well-commented code and documentation 
  • Positive attitude, willingness to ask questions and learn independently 
  • Working knowledge of version control systems (e.g. git) 
     

Preferred: 

  • Experience cleaning and reorganizing data in a common data science language (e.g. R, Python, MatLab) 
  • Conceptual understanding of automated testing and experience writing simple unit tests 
  • Comfortable in UNIX systems and working at the command line 
  • Experience in custom SQL query development 
  • Experience with cloud infrastructure (e.g. AWS / Azure) or containerization (Docker) 
     

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Software Development Engineer I/II - Bioinformatics Tools

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18394

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



The Gottardo Lab at Fred Hutch is a research lab within the computational biology program focused on creating statistical methods and software tools to analyze high throughput biological data. Our team works in collaboration with bench scientists and clinicians we work to understand severe diseases such HIV, malaria, and cancer and ultimately help develop vaccines and/or a cure. As a team, we value collaborative efforts, continued learning, and passion for our work.


Currently, the Gottardo Lab is working fully remote through at least summer 2021. You can learn more about the lab and lab members at rglab.org


The Software Development Engineer (SDE) I/II will help develop, implement and optimize computational cytometry software tools and analytic pipelines for clinical and non-clinical flow and mass cytometry data sets, leveraging R and C++. We are building open source tools to enable analysis, integration, and sharing of large cytometry data sets in order to facilitating reproducible research. The candidate will work as part of a team to support data analysis and software development and international collaborations. The candidate is expected to adhere to good software development practices (e.g. design, unit tests, documentation, code review), and participate in regular team meetings.

 

Our Commitment to Diversity

As a lab, we value inclusion and a diversity of backgrounds and perspectives to inform and improve our work. Given these values, we strive to make our recruitment and promotion processes transparent, fair, and supportive. Therefore, we strongly encourage all individuals with interest in the position to apply.

Responsibilities

  • Manage software refactoring and development to address user-raised issues in R-based cytometry tools (CytoVerse)
  • Develop custom pipelines to re-analyze and standardize cytometry data using novel automated-gating methods
  • Develop interactive visualizations in ShinyR to support users engaging with the results of standardized cytometry data

Qualifications

Minimum Qualifications SDE I:

  • Bachelor's in in STEM field or equivalent experience
  • 1+ years programming in C++
  • Familiarity with programming languages and concepts used commonly in data science (e.g. R / Python)
  • Working knowledge of Web stack, AWS / cloud computing
  • Working knowledge of Software version control (e.g. git )

 

Minimum Qualifications SDE II:

  • MSc in Bioinformatics, Data Science, Computer Science, Statistics or equivalent field or BSc with 3+ years’ experience also qualifies
  • 2+ years programming in C++
  • 1+ years in R or Python, including experience in data wrangling and package development
  • Working knowledge of Web stack, AWS / cloud computing
  • Working knowledge of Software version control (e.g. git )

 

Preferred Qualifications

  • Track record of contributions to open source software projects
  • Proficiency in Unix-alike operating system environment
  • Experience with containerization, e.g. Docker
  • Experience with workflow languages and infrastructure-as-code, e.g. NextFlow
  • Excellent written and oral communication skills


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists. 

Staff Scientist

FH Vaccine and Infectious Disease Division
Category: Staff Scientist
Seattle, WA, US
Job ID: 18056

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

The Stamatatos Lab, investigates the development of protective antibody responses during viral infections, by employing advanced Immunological, Molecular, Structural and Bioinformatic tools. The information generated from these studies is used to design immunogens to elicit similar antibody responses by vaccination.


We are seeking a Staff Scientist to assist with the development, validation, and testing of novel protein immunogens against HIV-1 and SARS-CoV-2. The candidate will be involved in the design of such immunogens and in the characterization of the B cell and antibody responses elicited in diverse animal models. The candidate will work independently and may supervise research technicians and PostDocs as needed.

Qualifications

  • PhD in immunology, or a related field, and 2+ years relevant postdoctoral experience
  • Expertise in B cell immunology is highly desirable
  • Experience with multicolor flow cytometry panels (>10 colors) and/or FACS
  • Experience with molecular biology and biochemistry, protein purification, and the analysis of protein-protein interactions is preferred
  • Experience with next generation sequencing and analysis would be beneficial
  • The candidate should have a proven track record of publication and written communication skills
  • Must be independent, show initiative, willingness to take up new skills and responsibilities, and be a team player
  • Excellent attention to detail and the ability to work independently are essential to success in this position
  • The candidate must be self-motivated, able to multitask and to work within a very collaborative environment


Applicants must submit:

  • Biosketch and at least 3 references
  • Cover letter discussing your interest in this position including statement of research interests and career goals

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Staff Scientist, Computational Biology

FH Vaccine and Infectious Disease Division
Category: Biostatistics, Bioinformatics and Computational Biology
Seattle, WA, US
Job ID: 18233

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



Fred Hutch launched the Translational Data Science Integrated Research Center (TDS IRC) in December 2018 to expand the breadth and depth of data science at our center. Led by Dr. Raphael Gottardo, the TDS IRC builds on several recent advances in biomedical sciences, including technologies that are driving generation of massive datasets, exponential growth of publicly available data, and revolutionary approaches in statistics, machine learning and artificial intelligence that are changing data analysis. Labs in the TDS IRC develop statistical methods and computational tools for managing and analyzing high throughput, high dimensional data and many labs work closely with translational researchers. Click here to learn more about the TDS IRC.

 

The TDS IRC is seeking a PhD level Staff Scientist in computational biology or related fields to lead efforts to expand computational biology support across the center. The ideal candidate will support large collaborative projects in a wide range of problems in oncology research and serve as a consultant/link for laboratory scientists seeking computational collaborations. The incumbent will collaborate with laboratory-based scientists, clinical investigators, biostatisticians, data scientists, programmers and computational biologists in two ways:

  • As a contributing member on teams developing novel technologies and data analysis tools for analyzing clinical and pre-clinical samples.
  • As a consultant, linking researchers across Fred Hutch to data scientists, programmers, and computational biologists with interest in collaboration.

Through these multi-disciplinary collaborations, the Staff Scientist will support and expand opportunities to apply novel tools and technologies to innovative pre-clinical and clinical studies.

Responsibilities

  • Consult with Fred Hutch researchers in search of support and collaboration to solve data science problems
  • Manage and set scientific priorities across projects
  • Develop and optimize computational pipelines to enable the integration and management of large and complex data sets
  • Develop well-documented, properly tested, open-source software for reproducible research
  • Interpret results from computational and statistical analysis
  • Assist with study design and analysis of pre-clinical and clinical trials
  • Participate in the dissemination of research findings
  • Co-author manuscripts for publication

Qualifications

Minimum qualifications:

  • PhD or equivalent degree in bioinformatics, computational biology, biostatistics, statistics, computer science, or a related field
  • Experience in analysis of next generation sequencing data
  • Excellent programming skills (python, R, C/C++, Java) including best software development practices (e.g., design, unit tests, documentation, code review)
  • Excellent interpersonal, oral and written communication skills
  • Strong work ethic
  • Ability to work in a team, and supervise junior team members
  • Ability to manage multiple projects and to meet deadlines

 

Preferred qualifications:

  • Experience in high-dimensional data, particularly at the single-cell level (e.g., scRNA-seq)
  • Experience in cloud computing (e.g., AWS)
  • Experience in immunology

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Staff Scientist, Vaccine Development

FH Vaccine and Infectious Disease Division
Category: Staff Scientist
Seattle, WA, US
Job ID: 17923

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

Responsibilities

The McGuire Lab is seeking a Staff Scientist to assist with the development, validation, and testing of novel vaccine candidates aimed at preventing HIV-1. The candidate will perform and in-depth characterization of the B cell and antibody response to novel HIV-1 candidate vaccines, perform data analysis, prepare reports/manuscripts, and supervise lab staff and related activities.

 

Assignments will be project oriented where goals are long term, rather that experiment oriented. The candidate will work independently and supervise research technicians and assist graduate students as needed. May be required to help with SARS-CoV-2 work as needed.

Qualifications

  • PhD in immunology, or a related field and 2+ years relevant postdoctoral experience. Expertise in B cell immunology is highly desirable.
  • Experience with multicolor flow cytometry panels (>10 colors) and/or FACS. Experience with molecular biology and biochemistry, including PCR, cloning, protein purification, and the analysis of protein-protein interactions is preferred. Experience with next generation sequencing and analysis would be beneficial.
  • The candidate should have a proven track record of publication and written communication skills
  • Must be willing to work with pre-clinical animal models including non-human primates. Must be independent, show initiative, willingness to take up new skills and responsibilities, and be a team player.
  • Excellent attention to detail and the ability to work independently are essential to success in this position
  • The candidate must be self-motivated, able to multitask and to work within a very collaborative environment

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