Paul Edlefsen, Ph.D.

Dr. Paul Edlefsen Ph.D.

Paul Edlefsen, Ph.D.

Senior Staff Scientist
Vaccine and Infectious Disease Division, Fred Hutch

Fax: 206.667.4378
Mail Stop: M2-C200


Harvard University, 2009, Ph.D. (Statistics)

Harvard University, 2005, A.M. (Statistics)

Wesleyan University, 2000, B.A. (Computer Science)

Research Interests

Statistical and computational methods for bioinformatics applications

Statistical modeling for genome sequence analysis

Frequentist, Bayesian, and Dempster-Shafer statistical modeling frameworks

The interface between computer science, statistics, and molecular biology, such as development of new informatics methods in genomics and post-genomics

Current Projects

Sieve analysis of HIV vaccine trials

Methods for parameter estimation of profile hidden Markov models of genomic sequence families

Nonparametric Dempster-Shafer models

Dilution assay copy number identification

Teaching and Mentoring Interests

Workshops and courses on statistics, sieve analysis, and profile HMMs

Proactive students with strong computational and/or statistical skills and a desire to work in an applied bioinformatics setting


Dr. Edlefsen in the News

Science without borders

Hutch News - October 16, 2017

Good news on the HSV-2 front

Science Spotlight - May 16, 2016