Matthew D. Gray, PhD
Matthew D. Gray, PhD
Senior Staff Scientist
Vaccine and Infectious Disease Division, Fred Hutch
Construction and evaluation of recombinant viral vectors for B cell engineering studies in mouse, human, and non-human primates. Molecular analyses of B cell responses to vaccination and tumor antigens. Binding and structural studies on neutralizing antibodies and their pathogen targets. Development of mono-, bi-, and tri-specific single-chain antibodies for B cell engineering studies and therapeutics. Optimization of Fc effector functions and circulation half-life for improved antibody therapeutics.
Education
University of Colorado at Boulder, 1991, PhD (Molecular, Cellular and Developmental Biology)
Carnegie-Mellon University, 1984, BS (Biological Sciences)
Research Interests
Construction and evaluation of recombinant viral vectors for B cell engineering studies in mouse, human, and non-human primates
Molecular analyses of B cell responses to vaccination and tumor antigens
Binding and structural studies on neutralizing antibodies and their pathogen targets
Development of mono-, bi-, and tri-specific single-chain antibodies for B cell engineering studies and therapeutics
Optimization of Fc effector functions and circulation half-life for improved antibody therapeutics