Matthew D. Gray, PhD

Dr. Matthew Gray PhD
Staff Scientist

Matthew D. Gray, PhD

Senior Staff Scientist
Vaccine and Infectious Disease Division, Fred Hutch

Mail Stop: E5-110

Construction and evaluation of recombinant viral vectors for B cell engineering studies in mouse, human, and non-human primates. Molecular analyses of B cell responses to vaccination and tumor antigens. Binding and structural studies on neutralizing antibodies and their pathogen targets. Development of mono-, bi-, and tri-specific single-chain antibodies for B cell engineering studies and therapeutics. Optimization of Fc effector functions and circulation half-life for improved antibody therapeutics.

Education

University of Colorado at Boulder, 1991, PhD (Molecular, Cellular and Developmental Biology)

Carnegie-Mellon University, 1984, BS (Biological Sciences)

Research Interests

Construction and evaluation of recombinant viral vectors for B cell engineering studies in mouse, human, and non-human primates

Molecular analyses of B cell responses to vaccination and tumor antigens

Binding and structural studies on neutralizing antibodies and their pathogen targets

Development of mono-, bi-, and tri-specific single-chain antibodies for B cell engineering studies and therapeutics

Optimization of Fc effector functions and circulation half-life for improved antibody therapeutics