Fish oil and fiber together reduce colon tumor formation in animals. In humans, there are only studies looking at each separately. We want to understand how the combination works in healthy humans. We will look at changes in health markers and in the gut microbiome.
Participants will take study supplements during two periods. For one month it will be fish oil and corn fiber and for the other, corn oil and a non-fiber corn product (placebo). We will compare the effects within each person.
The purpose of the study is to answer scientific questions. Participants must be able to visit Fred Hutchinson Cancer Research Center's campus at South Lake Union throughout the 4-month study. Participants will receive $250 for completing the study.
Participants will take oil and fiber supplements for two 30-day periods, with a 60-day period in between. The study oil comes in small glass bottles containing about 1 tablespoon of oil. Participants take two a day. It has a very mild taste and can be added to food, mixed with liquid or taken straight. The fiber supplement is in powder form and participants take one packet a day. It can be easily added to foods or liquids.
Participants will collect stool samples at the beginning, middle (day 15) and end of each of the two 30-day intervention periods.
Participants will visit Fred Hutch during each 30-day period (before, mid and after) to get the supplements, deliver stool samples and have blood drawn.
To see if you are eligible based on Body Mass Index, find your height in the left-hand column labeled ”Your Height”. Move across to “Your Weight”. If you weigh between the weights stated, you may be eligible for this study.
Associate Director, Public Health Sciences Division, Fred Hutch
Senior Staff Scientist, Fred Hutch
Distinguished Professor and University Faculty Fellow, Texas A&M