Join us in a study of the benefits of fish oil & fiber!
Fish oil and fiber together reduce colon tumor formation in animals. In humans, there are only studies looking at each separately. We want to understand how the combination works in healthy humans. We will look at changes in health markers and in the gut microbiome.
Participants will take study supplements during two periods. For one month it will be fish oil and corn fiber and for the other, corn oil and a non-fiber corn product (placebo). We will compare the effects within each person.
The purpose of the study is to answer scientific questions. Participants must be able to visit Fred Hutchinson Cancer Center's campus at South Lake Union throughout the 4-month study. Participants will receive $250 for completing the study.
You may be eligible if you are healthy, between 50-75 years old, and:
- live in the greater Seattle area
- don't eat a lot of vegetables
- don't smoke or use recreational drugs
- don't drink more than 2 alcoholic drinks most days
- have not taken antibiotics in the past 3 months
- don't take (more than once/week NSAIDs) aspirin, ibuprofen, naproxen) or Lovaza,
- don't take blood clottng medications such as Coumadin, Eliquis, Plaviz, Xarelto
- have a BMI (Body Mass Index) between 18 and 30. To see if you are eligible, see chart below.
Thank you for your interest in our study. We have completed our recruitment of participants and are no longer enrolling into the study.
Study Activities
Participants will take oil and fiber supplements for two 30-day periods, with a 60-day period in between. The study oil comes in small glass bottles containing about 1 tablespoon of oil. Participants take two a day. It has a very mild taste and can be added to food, mixed with liquid or taken straight. The fiber supplement is in powder form and participants take one packet a day. It can be easily added to foods or liquids.
Participants will collect stool samples at the beginning, middle (day 15) and end of each of the two 30-day intervention periods.
Participants will visit Fred Hutch during each 30-day period (before, mid and after) to get the supplements, deliver stool samples and have blood drawn.
The table shows a range of recommended body weights for adults at different heights. As height increases from 4'10" to 6'4", the healthy weight range also increases. Each height lists a minimum and maximum weight to help understand general proportional body size.
| Your Height | Your Weight (lbs) |
|---|---|
| 4'10" | 86 – 143 lbs |
| 4'11" | 89 – 148 lbs |
| 5'0" | 92 – 153 lbs |
| 5'1" | 95 – 158 lbs |
| 5'2" | 98 – 164 lbs |
| 5'3" | 101 – 169 lbs |
| 5'4" | 104 – 169 lbs |
| 5'5" | 108 – 180 lbs |
| 5'6" | 112 – 186 lbs |
| 5'7" | 115 – 191 lbs |
| 5'8" | 118 – 197 lbs |
| 5'9" | 122 – 203 lbs |
| 5'10" | 126 – 209 lbs |
| 5'11" | 129 – 215 lbs |
| 6'0" | 133 – 221 lbs |
| 6'1" | 137 – 227 lbs |
| 6'2" | 140 – 223 lbs |
| 6'3" | 144 – 240 lbs |
| 6'4" | 148 – 246 lbs |
Principal Investigators
Johanna Lampe, Ph.D., R.D.
Associate Director, Public Health Sciences Division, Fred Hutch
Meredith Hullar, Ph.D.
Senior Staff Scientist, Fred Hutch
Robert Chapkin, Ph.D.
Distinguished Professor and University Faculty Fellow, Texas A&M