Fish & Fiber Study

Fish oil and fiber together reduce colon tumor formation in animals. In humans, there are only studies looking at each separately. We want to understand how the combination works in healthy humans. We will look at changes in health markers and in the gut microbiome.

Participants will take study supplements during two periods. For one month it will be fish oil and corn fiber and for the other, corn oil and a non-fiber corn product (placebo). We will compare the effects within each person.

The purpose of the study is to answer scientific questions. Participants must be able to visit Fred Hutchinson Cancer Center's campus at South Lake Union throughout the 4-month study. Participants will receive $250 for completing the study.

You may be eligible if you are healthy, between 50-75 years old, and:

• live in the greater Seattle area
• don't eat a lot of vegetables
• don't smoke or use recreational drugs
• don't  drink more than 2 alcoholic drinks most days
• have not taken antibiotics in the past 3 months
• don't take (more than once/week NSAIDs) aspirin, ibuprofen, naproxen) or Lovaza,
• don't take blood clottng medications such as Coumadin, Eliquis, Plaviz, Xarelto
• have a BMI (Body Mass Index) between 18 and 30. To see if you are eligible, see chart below.