Cell biologist Dr. Sue Biggins believes in staying busy and doing whatever it takes to arrive at answers to unsolved major questions. It's a pursuit that led her from music to medical school, then into research where she's finding answers to fundamental biological questions.
Biggins describes her breakthrough research in the March 19 online edition of the Journal of Cell Biology. In the profile, she discusses what her Basic Sciences Division lab is discovering about kinetochores and how they control mitosis, the cell division process.
"There are several different sub-complexes that make up the kinetochore, but how they fit together to regulate the spindle checkpoint or bind to microtubules is unknown," Biggins said. "Our approach to studying these questions is to do it in vitro with purified kinetochores.
Read the complete interview with Biggins in the scientific journal.