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Cancer immunotherapy gets assist from micro-scale engineering
With new molecular 'handles' and stimulating signals, metallic thin films become a stronghold for cancer-killing immune cells
New Scientific Publications
Each week, Fred Hutch librarians search PubMed and Web of Science to discover new papers published by Fred Hutch authors
Week of December 08, 2019
Try, try again: Can a 2nd dose of CAR T cells succeed when the first fails?
First-of-its-kind study offers early indication of factors linked to increased odds of success for patients out of options
Targeting metastatic breast cancer with CAR T-cell immunotherapy
$4M 'Breakthrough' award funds collaborative research aimed at destroying dormant disseminated tumor cells
Adoptive transfer of engineered T cells prolongs survival in preclinical ovarian cancer
From the Greenberg lab, Clinical Research Division, and the Vaccine and Infectious Disease Division
Dr. Cameron Turtle receives Anderson Family Endowed Chair for Immunotherapy
Gift will ‘help new ideas move rapidly toward the patients who need them’
The New Yorker spotlights Fred Hutch’s pioneering cancer research
‘The Promise and Price of Cellular Therapies’ by Siddhartha Mukherjee traces journey from bone marrow transplantation to immunotherapy
“Exciting” but early results in trial of immunotherapy for myeloma
Cancer cells disappeared rapidly in patients with high-risk, treatment-resistant disease
Fred Hutch at ASH: Combo CAR T-cell therapies, long-term outcomes for CAR T patients, early findings on a CAR T for multiple myeloma, gene therapy for sickle cell, and T cells and the microbiome
The 60th American Society of Hematology Annual Meeting will take place Dec. 1–4 in San Diego
Two new grants to fuel metastatic breast cancer research
Drs. Erica Goddard and Mark Headley will use their awards to study how breast cancer cells spread to distant organs – and how to stop them.
Forbes '30 Under 30' lists Hutch immunotherapy researcher Alex Salter
Grad student on short list of young health care influencers
Stronger and faster is not always better
From the Riddell, Paulovich Labs, Clinical Research Division and Gottardo Lab, Vaccine and Infectious Disease Division.
First in-depth profile of CAR T-cell signals suggests how to improve immunotherapy
A Science Signaling paper reports how two common CAR designs impact T-cell efficacy against cancer in the laboratory
Nanoparticles open doors to cancer-fighting CAR T cells
Tiny liposome-based drug carriers make tumors more vulnerable to targeted immunotherapy
Fred Hutch at ASCO
Immunotherapy advances, insights into health economics and leadership awards dominate oncology gathering
Dr. Reema Jain developing methods to isolate, manipulate blood stem cells for T-cell therapy
Funding from Immunotherapy Integrated Research Center supports postdoc’s work
Jump-starting innovative projects exploring pathogen-associated cancers
Pathogen-Associated Malignancies Integrated Research Center awards first round of pilot funding supporting researchers studying H. pylori, EBV and the microbiome
How new drugs become available to more patients
Filling in the unknowns on the balance between risk and benefit
CAR T cells manufacture upgrades
From the Till lab, Clinical Research Division
10 highlights of Fred Hutch science in 2017
A look back at notable discoveries in cancer immunotherapy, HIV prevention and more
New insights into CAR T-cell therapy's potential side effects
Detailed study of cytokine release syndrome and neurologic toxicities could help make emerging cancer immunotherapies safer