Science Spotlight

Science Spotlight

New Spotlight Team

From the left: Science Spotlight editors Yiting Lim (Basic Sciences), Kyle Woodward (Clinical Research), Nicolas Chuvin (Human Biology), Maggie Burhans (Public Health Sciences) and Brianna Traxinger (Vaccine and Infectious Disease)

Photo by Robert Hood / Fred Hutch

Current Stories

A cold case reopened for Merkel cell carcinoma
Merkel cell polyomavirus tumor antigens do not bind ubiquitin ligases as previously reported, thus questioning the accepted model of transformation and tumorigenesis by MCPyV.
A corkscrew tale for H. pylori
Helical shape of H.pylori unexpectedly governs more pathogenicity than motility in chronic infections.
CUT&Tag for the win
Cleavage Under Targets and Tagmentation efficiently profiles the epigenome of live cells in small numbers and single cells
Deep mutational scanning predicts pandemic influenza sequences
Deep mutational scanning of influenza polymerase reveals putative viral adaptations in the avian to human direction
In cell polarity, microtubules are important after all
Microtubules play an essential role in the maintenance of planar cell polarity in the floorplate of the zebrafish neural tube
Natural language processing as a research aid
The use of artificial intelligence to ascertain gene mutation test results from electronic pathology reports may be an efficient alternative method to time-intensive manual abstraction.
Regulatory T cells maintain “virtual” immunologic memory
Regulatory T cells limit CD8+ virtual memory populations, maintaining space in the T cell niche for virus-specific responses
TCR-engineered T cell therapy enhanced by modulating macrophages
Modulation of tumor associated macrophages with agonistic anti-CD40 can augment engineered antigen-specific T cells in a model of pancreas cancer.
Teasing out the association between oral contraceptives and breast cancer risk
Recent oral contraceptive use is differentially associated with risk for breast cancer by molecular subtypes in premenopausal women.
Turning down the heat
Low dose radiation conditioning for hematopoietic stem cell transplant carries lower risk for developing new malignancies.

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Editors

Yiting Lim
Basic Sciences Division

Nicolas Chuvin
Human Biology Division

Maggie Burhans, PhD
Public Health Sciences Division

Brianna Traxinger
Vaccine and Infectious Disease Division

Kyle Woodward
Clinical Research Division

Julian Simon, PhD
Faculty Mentor
Clinical Research Division
and Human Biology Division

Allysha Eyler
Publication Tracking
Arnold Digital Library
 

Recently Published Papers

  • Basic Sciences Division
  • Clinical Research Division
  • Human Biology Division
  • Public Health Sciences Division
  • Vaccine and Infectious Disease Division

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