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New projects advance health equity research
Two $1M grants support efforts to pinpoint novel prostate cancer biomarkers, improve clinical trial enrollment and inclusion
Hutch News
November 28, 2023
Tags
Good News
Public Health Sciences
Jason Mendoza
Gavin Ha
Ha Lab
Office of Community Outreach and Engagement
OCOE
Prostate Cancer
clinical trials
health equity
health disparities
cancer consortium
biomarkers
Human Biology
Share
Cataloging bacterial diversity within tumor samples
From the Bullman Lab, Human Biology Division and Johnston Lab, Vaccine and Infectious Disease Division
Science Spotlight
November 20, 2023
Tags
Susan Bullman
human microbiome
protocols
cancer bacteria
Human Biology
Christopher Johnston
Vaccine and Infectious Disease
Share
Extending efficacy for CAR T-cell therapies
Dr. Shivani Srivastava receives NCI MERIT Award to investigate how to improve engineered cancer immunotherapies against solid tumors through reservoirs of self-renewing immune cells
Hutch News
October 09, 2023
Tags
Shivani Srivastava
Human Biology
Immunotherapy Integrated Research Center
CAR t-cell
adoptive t cell therapy
genetically engineered t cells
cancer immunotherapy
solid tumor
Good News
Share
New technique could help make precision medicine more widely available
Simple CUT&Tag adaptation gives information about genetic regulatory elements in formalin-fixed tumor samples
Hutch News
October 04, 2023
Tags
Steven Henikoff
Eric Holland
Basic Sciences
Human Biology
chromatin
gene regulation
micro rna
cancer
brain cancer
Share
From the bench to Hutch services: Refining gene-editing methods for HSPCs used in pre-clinical applications
From the Paddison lab, Human Biology Division
Science Spotlight
August 21, 2023
Tags
Patrick J Paddison
Human Biology
CRISPR
hematopoietic stem cell
mice
genetically engineered mice
gene editing
Share
Does prostate cancer have a goldilocks mentality when it comes to androgens?
From the Nelson lab, Human Biology and Clinical Research Divisions
Science Spotlight
August 21, 2023
Tags
Peter Nelson
Prostate Cancer
androgen receptor
androgen deprivation therapy
Human Biology
Clinical Research
tumor suppressor
Share
RNA stability may play a role in prostate cancer
New research links mutations in RNA region that helps regulate protein production to progression and drug resistance
Hutch News
July 28, 2023
Tags
Prostate Cancer
prostate cancer progression
drug resistance
genetic mutation
translational control
RNA
Human Biology
Andrew Hsieh
Cancer etiology - prevention - outcomes
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Dr. Sita Kugel receives V Foundation Translational Research Award
Grant makes possible a clinical trial of targeted treatment for pancreatic cancer
Hutch News
June 27, 2023
Tags
Sita Kugel
Human Biology
Good News
Pancreatic Cancer
gene transcription
patient-derived xenograft model
precision medicine
precision oncology
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‘Dux’ and Cover: an enigmatic protein’s potential role in immune evasion
From the Tapscott Lab, Human Biology Division
Science Spotlight
June 19, 2023
Tags
Tapscott Lab
Human Biology
DUX4 gene
facioscapulohumeral dystrophy
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A seesaw between transcription and translation restrains bladder carcinogenesis
From the Hsieh Lab, Human Biology Division
Science Spotlight
June 19, 2023
Tags
Hsieh Lab
Human Biology
gene transcription
translational control
tumor suppressor
Share
Boost and attack approach for metastatic prostate cancer therapy!
From the Lee Lab, Human Biology and Clinical Research Divisions, Cancer Consortium
Science Spotlight
June 19, 2023
Tags
John Lee
Human Biology
Clinical Research
cancer consortium
CAR t-cell
cytokines
anti-tumor immune responses
Prostate Cancer
Share
Brain cancer expert Dr. Eric Holland receives Endowed Chair in Cancer Biology
Chair recognizes comprehensive vision, contributions to solid tumor research
Hutch News
May 05, 2023
Tags
Eric Holland
brain cancer
Cancer etiology - prevention - outcomes
data science
precision oncology
Human Biology
Good News
endowed chair
Share
Improving immunotherapy for advanced prostate cancer
Preclinical work identifies better target and recruits more immune cells to make CAR-T therapy work for solid tumors
Hutch News
April 27, 2023
Tags
John Lee
Human Biology
Prostate Cancer
immunotherapy
CAR t-cell
tumor microenvironments
metastatic cancer
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Researchers discover molecular fail-safe that keeps bladder tissues from turning cancerous
Bladder cells’ strategy blocks cancer-causing genetic programs, could be new therapeutic target
Hutch News
April 20, 2023
Tags
Andrew Hsieh
Bladder Cancer
Cancer etiology - prevention - outcomes
Human Biology
precision oncology
Share
Untangling how body location promotes cancer
Beronja Lab postdoc Rachel Lex receives ACS fellowship to uncover regional factors driving tumor development
Hutch News
April 19, 2023
Tags
skin cancer
stem cell research
cancer stem cells
stem cell
stem cell expansion
tumor microenvironments
microbiome
Cancer etiology - prevention - outcomes
Slobodan Beronja
Beronja Lab
Human Biology
Good News
Share
Classifying prostate cancer subtypes from liquid biopsies
From the Ha and Nelson labs, Human Biology Division
Science Spotlight
April 17, 2023
Tags
Prostate Cancer
Prostate Cancer SPORE
liquid biopsy
patient-derived xenograft model
Gavin Ha
Peter Nelson
Henikoff Lab
Public Health Sciences
Human Biology
Herbold Computational Biology Program
precision oncology
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Introducing the Brain-UMAP: a reference map of the human brain
From the Holland lab, Human Biology Division
Science Spotlight
April 17, 2023
Tags
glioblastoma
brain cancer
pediatric brain cancer
oncoscape
Seattle Translational Tumor Research
Eric Holland
Human Biology
Share
For the first time (in cryo-EM): A3G and Vif structure revealed
From the Emerman lab, Human Biology and Basic Sciences Divisions
Science Spotlight
March 20, 2023
Tags
Basic Sciences
Human Biology
Michael Emerman
Cryo-EM
HIV-1
apobec3g
virus-host interactions
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This little piggie went to the clinic: pigs as a model of DUX4-linked muscular dystrophy
From the Tapscott Lab, Human Biology Division
Science Spotlight
March 20, 2023
Tags
Tapscott Lab
facioscapulohumeral muscular distrophy
Human Biology
DUX4 gene
Share
Panning for gold in a dependent-sea of genes
From the Emerman Lab, Human Biology and Basic Sciences Divisions
Science Spotlight
March 20, 2023
Tags
Human Biology
Basic Sciences
hiv
Emerman Lab
CRISPR
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Fred Hutchinson Cancer Center
Hutch News
Last Modified, August 15, 2023