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New Science Spotlight Articles
Every month, Fred Hutch postdoc writer/editors summarize two papers from each of our scientific divisions to stimulate collaborations across campus
March 20, 2023
Fred Hutch hosts inaugural Dr. E. Donnall Thomas Symposium
Event draws leading researchers in transplantation, gene and cell therapy
Sifting through the haystack: Optimizing hematopoietic stem cell purification for gene therapy
From the Kiem Lab, Clinical Research Division
Timothy Ray Brown, who inspired millions living with HIV, dies of leukemia
For more than a decade after a stem cell transplant, he was the only person known to be cured of HIV/AIDS
Tip Sheet: Colorectal cancer, COVID-19 super-spreading, gene therapy for herpes, contagious cancer in Tasmanian devils – and more
Summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.
A cure for herpes? There is progress to report
Mouse studies show gene therapy can cause big drop in latent infections
DNA barcoding allows tracking of clonal dynamics after gene therapy
From the Adair and Kiem Groups, Clinical Research Division
$3.5M grant to develop safer treatment for inherited blood disorders
Scientists will study radioactive particles that can precisely deliver a potent punch
The present and future of science intersect in Seattle
Highlights from the annual meeting of the American Association for the Advancement of Science
Future of medicine: Body heal thyself
Panel of Hutch scientists talked gene therapy, big data and financial toxicity to reporters at annual AAAS meeting
Dr. Jennifer Adair receives Fleischauer Family Endowed Chair in Gene Therapy Translation
Gift will support 'inspirational, essential' research to help gene therapy go global
Dr. Hans-Peter Kiem speaks about HIV and making gene therapy more accessible at TEDxSeattle
His talk is now available online
A look at emerging sickle cell disease therapies
Teams at the University of Washington School of Pharmacy and Fred Hutch will model the clinical and economic burden of sickle cell disease and the potential benefits of emerging therapies
Targeting a subset of stem cells shows lasting, therapeutically relevant gene editing in blood cells
A new Science Translational Medicine paper is first to report how editing a portion of stem cells with CRISPR/Cas9 is sufficient for long-term reactivation of therapeutic hemoglobin
Special delivery: Gold nanoparticles ship CRISPR cargo
Fred Hutch scientists used their new golden courier to edit genes tied to HIV, genetic blood disorders
Could gold be the key to making gene therapy for HIV and other blood disorders more accessible?
A proof-of-principle study published in Nature Materials shows that gold nanoparticles loaded with CRISPR and other gene-editing tools safely and effectively edited blood stem cells. (Photos, diagram available for media use.)
Seattle mayor and melanoma survivor Jenny Durkan visits Fred Hutch
Mayor shares personal story as Hutch scientists outline the future of cancer therapy
Scientists strategize to stop HIV infections, work toward cure
A hot topic for a big scientific conference convening in Seattle
Drs. Denise Galloway and Hans-Peter Kiem receive endowed chairs
Paul Stephanus Memorial Endowed Chair to Galloway; Stephanus Family Endowed Chair for Cell and Gene Therapy to Kiem
Fred Hutch at ASH: Combo CAR T-cell therapies, long-term outcomes for CAR T patients, early findings on a CAR T for multiple myeloma, gene therapy for sickle cell, and T cells and the microbiome
The 60th American Society of Hematology Annual Meeting will take place Dec. 1–4 in San Diego