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The future of blood stem cell gene therapy is in vivo
From the Lieber and Kiem Labs, Hematologic Malignancies Program, Cancer Consortium.
Testing cord blood transplants as a cure for leukemia — and HIV
New clinical trial at several U.S. cancer centers will enroll people living with HIV and advanced leukemia
AIDS@40: Stories of hope and heroes
The people and the science devoted to stopping HIV
Location, location, location: therapeutic T cells traffic to HIV reservoirs
From the Kiem Lab, Clinical Research Division
Tip Sheet: Diversity in vaccine clinical trials, behind-the-scenes look at COVID-19 biostats, new cell therapy approved, plus meet ‘Megasphaera hutchinsoni’
Summaries of recent Fred Hutch research findings and other news
Hutch research helps launch new genomic medicine company
Ensoma receives $70 million in financing to develop genome modification technologies via a single injection
Sifting through the haystack: Optimizing hematopoietic stem cell purification for gene therapy
From the Kiem Lab, Clinical Research Division
Timothy Ray Brown, who inspired millions living with HIV, dies of leukemia
For more than a decade after a stem cell transplant, he was the only person known to be cured of HIV/AIDS
Antigen boost helps CAR-T cells control viral load in SHIV infected animals
From the Kiem Group, Clinical Research Division
DNA barcoding allows tracking of clonal dynamics after gene therapy
From the Adair and Kiem Groups, Clinical Research Division
$3.5M grant to develop safer treatment for inherited blood disorders
Scientists will study radioactive particles that can precisely deliver a potent punch
Dr. Hans-Peter Kiem elected vice president of American Society of Gene & Cell Therapy
After serving 1 year as vice president, Kiem will serve as president-elect and president of the society
Dr. Hans-Peter Kiem speaks about HIV and making gene therapy more accessible at TEDxSeattle
His talk is now available online
Science on the horizon
Fred Hutch experts make predictions for science trends, advances in 2020
Gimme shelter: CRISPR hides healthy cells from leukemia drug
In mouse study, gene-edited cells stay safe as immunotherapy attacks cancer
World AIDS Day: Stepping up the search for a cure
New funding from Gates Foundation and NIH give vote of confidence for an audacious goal
Scientists gather in Seattle to share strategies for an HIV cure
Workshop focuses on ways to lower cost, broaden reach of gene therapy
Conference on gene therapy for HIV cures will highlight progress and challenges ahead
Dr. Robert Siliciano, keynote speaker, discovered why AIDS drugs alone cannot cure HIV
Targeting a subset of stem cells shows lasting, therapeutically relevant gene editing in blood cells
A new Science Translational Medicine paper is first to report how editing a portion of stem cells with CRISPR/Cas9 is sufficient for long-term reactivation of therapeutic hemoglobin