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From dream to legacy: Couple accelerates lung cancer research
Vinh Bui and Tram Le establish endowed chair supporting Dr. David MacPherson
Control de la quimiorresistencia con KEAP en el CPCP
Del Laboratorio MacPherson, División de Biología Humana
KEAP-ing chemoresistance at bay in SCLC
From the MacPherson Lab, Human Biology Division
Fred Hutch study finds genetic driver of drug resistance in small cell lung cancer
Researchers use CRISPR-Cas9 gene-editing tool on tumor cells grown in mice to better model how tumors that initially respond to chemotherapy become resistant
Cell free DNA profiling may unlock the key to studying small cell lung cancer
MacPherson and Ha Labs in the Division of Human Biology
Targeted new approach and computational tools reveal lung cancer subtypes hiding in patterns in cell-free DNA
Innovative strategy a step toward liquid biopsy to detect, monitor aggressive small cell lung cancer
When antibodies become anti-body
From the Houghton and Lampe labs, Clinical Research and Public Health Sciences Divisions
MacPherson Lab puts immunologically cold cancers in the hot seat with combination therapy
From the MacPherson and Srivastava Labs, Cancer Basic Biology and Cancer Immunology Programs, Cancer Consortium.
CD133 auto-antibodies shine a light on early-stage small cell lung cancer
From the Dr. Paul D Lampe, Dr. Christopher Li, and Dr. A McGarry Houghton Labs, Cancer Epidemiology, Prevention and Control and Cancer Immunology Programs, Cancer Consortium.
Making immunotherapy more effective against small cell lung cancer
Human trial opens after experimental drug improves tumor growth suppression in mice
Tip Sheet: Colorectal cancer, COVID-19 super-spreading, gene therapy for herpes, contagious cancer in Tasmanian devils – and more
Summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.
New insights into drug resistance in small cell lung cancer
Scientists discover a single gene’s outsized role in drug resistance — and use its vulnerability to re-sensitize tumors to chemotherapy in preclinical models
In cancer, the context 'makes' the mutation
Whether a mutated gene suppresses or promotes small-cell lung cancer depends on other mutations
Q&A: A new focus on small cell lung cancer
Dr. David MacPherson discusses the state of small cell lung cancer research, how his lab is tackling this deadly disease, and what makes him excited for the future
Path to a targeted treatment for small-cell lung cancer?
Researchers show how common mutation in SCLC makes mouse tumors more vulnerable to certain cancer drugs
Good News: Fred Hutch joins coalition that seeks to increase transparency on life science career prospects
Celebrating faculty and staff achievements