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DUX in a row: Exploring genetic repression across the D4Z4 repeat
From the Tapscott Lab, Clinical Research and Human Biology Divisions
Polycomb repressor proteins get trapped in a web of HSATII DNA upon DUX4 activation, leading to DNA damage
From the Tapscott Lab, Human Biology Division
To make itself heard, DUX4 steals the mic and turns the noise down
From the Tapscott and Hsieh Labs, Human Biology Division
Ephemeral yet consequential: DUX4 activates an early embryonic program in cancer cells
From the Tapscott lab, Human Biology Division
‘Dux’ and Cover: an enigmatic protein’s potential role in immune evasion
From the Tapscott Lab, Human Biology Division
This little piggie went to the clinic: pigs as a model of DUX4-linked muscular dystrophy
From the Tapscott Lab, Human Biology Division
Pathogenic RNAs in muscular dystrophy
From the Tapscott lab, Human Biology division
DUX4 lights up its own airstrip
From the Tapscott lab, Human Biology Division
DUX4 rears its head in cancers to fend off the immune system
From the Bradley and Tapscott labs, Public Health Sciences, Basic Sciences, and Human Biology Divisions
FSHD myoblasts are powerless when faced with stress
From the Bradley lab, Public Health Science Division, and the Tapscott lab, Human Biology Division
The measure of a chromatin binding protein
From the Tapscott lab, Human Biology Division
It takes two to silence DUX4
From the Tapscott lab, Human Biology Division
Fred Hutch GSK Partnership - Fred Hutchinson Cancer Research Center
Collaboration represents first U.S. institution chosen to participate in GSK academic-industry partnership