COVID-19 Trials and Studies

Volunteers Are Critical to COVID-19 Studies

Fred Hutch is conducting a number of therapeutic and non-therapeutic COVID-19 studies including treatment trials, observational studies and vaccine trials. To end this pandemic, we need volunteers of all ages, races, ethnicities and backgrounds to participate in research studies. That includes volunteers who have had a COVID-19 diagnosis and those who have never had a COVID-19 diagnosis.

The following studies and trials are currently enrolling participants. Participants may be eligible to enroll in certain studies concurrently. If you are unsure, please contact us to learn more.



Treatment Trials  |   Observational Studies   |  Vaccine Trials

young woman going through a medical exam in doctor's office

Treatment Trials

Fred Hutch researchers are conducting studies using investigational therapeutics to identify promising treatments for people diagnosed with COVID-19. These studies are researching autoimmune disease drugs, antiviral drugs and antibodies that may fight COVID-19.

Participants in observational studies may provide researchers with data and information through questionnaires, medical exams or other tests.

Trials Open For Enrollment

DVX201 - Deverra Therapeutics, Inc.

This study is a Phase 1 study to determine the highest tolerated dose of an investigational cell therapy called DVX201 in patients hospitalized with COVID-19. DVX201 is an allogeneic NK (natural killer) cell therapy. NK cells are a normal part of your immune system that have the ability to identify and kill cells in the body that are infected by viruses such as COVID-19. There is evidence that both NK cell exhaustion and low numbers of NK cell in the blood occur in COVID-19 patients, and this may contribute to worsening of the infection. The study will enroll adults 18-80 years of age.

young woman undergoing a nasal swab

Observational Studies

Fred Hutch researchers are conducting observational studies of people who are at risk for or have been diagnosed with COVID-19. These studies may observe the effect of a risk factor, a diagnostic test, a treatment or other interventions. The data collected can help advance understanding of how the disease progresses as well as its causes.

Participants in observational studies may provide researchers with data and information  through questionnaires, medical exams or other tests.

Studies Open For Enrollment

Seattle Coronavirus Assessment Network (SCAN)

Stopping the COVID-19 pandemic requires a better understanding of how the disease spreads. The SCAN study provides free at-home testing for COVID-19. The findings will help the research partners, including Public Health — Seattle & King County, to keep people informed and make data-driven decisions on how to protect the community.

Seattle COVID Cohort Study

Fred Hutch's Dr. Julie McElrath is leading the Seattle COVID Cohort Study, an observational study, focusing on individuals who have confirmed COVID-positive results from the last 30 days. This study will help us gain an understanding of how the immune system works in response to COVID, and enable us to find better ways to prevent and treat the virus.”

Apple Respiratory Study

Researchers from the Seattle Flu Study and the University of Washington are teaming up with Apple to understand how everyday devices, like an Apple Watch or iPhone, can be used to predict illnesses like COVID-19. We are looking for people who live in the greater Seattle area and may have higher than normal risk of respiratory illness because of frequent exposure to other people through work or other activities, health conditions, or other factors.

doctor administering a vaccination to a patient

Vaccine Trials

Fred Hutch is working with the National Institutes of Health and others to design human clinical trials for the most promising vaccine candidates developed by industry partners. These candidates must pass three phases of human testing to ensure they are safe and effective in preventing a disease. Typically, a vaccine is tested on healthy individuals.

Participants in a vaccine trial can expect to be carefully evaluated prior to receiving a vaccine and then closely monitored.

Trials Open For Enrollment

COVID-19 Prevention Trials Network

Fred Hutch is the operations center for the nationwide COVID-19 Prevention Trials Network (CoVPN). The CoVPN is conducting Phase 3 vaccine studies and is currently recruiting participants from across the U.S. to join the studies.

Patient Katrina Freeman at the Seattle Cancer Care Alliance
Patient Katrina Freeman at the Seattle Cancer Care Alliance Photo by Robert Hood / Fred Hutch

Clinical Trials for Immune Compromised Patients

Fred Hutch researchers developing guidelines to help physicians with the diagnosis and management of COVID-19 in hematopoietic and cellular therapy patients, and continue to develop best practices for managing cancer care during the COVID-19 pandemic. These efforts include developing and implementing infection and environmental control policies, coordinating institution-wide efforts, outpatient considerations, treatment decisions, ethical considerations, hospital management of oncology patients, and employee and leadership well-being.

Coronavirus Research

Fred Hutch is an important part of the international scientific response to the pandemic — tracking and modeling the virus' spread, developing diagnostic tests, designing vaccine trials, and working to prevent future outbreaks.

Our COVID-19 Research
Dr. Jesse Bloom standing in front of a whiteboard displaying scientific notations

Our COVID-19 Researchers

Our scientists are applying decades of expertise in the laboratory for solving disease problems and the development of new prevention and treatment options.

Meet Our Scientists
Research technician working on COVID-19 in Julie McElrath's lab

How Vaccines are Developed

Our researchers are working to develop a safe and effective vaccine for COVID-19. The process involves intense laboratory efforts and testing.

Our Vaccine Research
Last Modified, October 15, 2021