Hutch News
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Hitting ‘undo’ to cure Sickle Cell Disease
From the Lieber and Kiem Labs, Hematologic Malignancies Program, Cancer Consortium.
Panning for gold in a dependent-sea of genes
From the Emerman Lab, Human Biology and Basic Sciences Divisions
Uncovering cancer growth genes that have each other’s back when the other is down
From the Berger Lab, Human Biology Division
Searching beyond the streetlight to uncover functional protein domains
From the Paddison Lab, Human Biology Division
Could gene twins team up against cancer?
New approach uncovers gene duplications that could be targets for cancer drugs
TOP delivery of CRISPR-Cas9 machinery to primary T cells
From the Overbaugh Lab, Human Biology Division
Advances in blood disorders research continue despite COVID-19
Expanding use of CAR T-cell therapies, gene editing lead to insights at virtual annual meeting of the American Society of Hematology
Improved CRISPR-Cas9 delivery method allows for fast and precise knockouts
From the Paddison lab, Human Biology Division
¿La cura del herpes? Hay avances que reportar
Los estudios con ratones muestran que la terapia génica puede reducir muchísimo las infecciones inactivas
Discovering new strategies used in arms race between bacteria and the viruses that infect them
Dr. Kevin Forsberg tapped for NIAID New Innovators Award to study arms race between viruses and bacteria
Your vote needed! Hutch science competes in 'STAT Madness'
Studies by Drs. Justin Taylor, Robert Bradley are finalists in annual competition for best biomedical advance
Catching CRISPR/Cas9 in (Pig Farm)
From the Bradley lab, Basic Sciences and Public Health Sciences Divisions
Gimme shelter: CRISPR hides healthy cells from leukemia drug
In mouse study, gene-edited cells stay safe as immunotherapy attacks cancer
How a common cancer mutation actually drives cancer — and how to correct it
High-tech approach solves ‘real mystery’ in many cancers
Targeting a subset of stem cells shows lasting, therapeutically relevant gene editing in blood cells
A new Science Translational Medicine paper is first to report how editing a portion of stem cells with CRISPR/Cas9 is sufficient for long-term reactivation of therapeutic hemoglobin
Improving CRISPR with a heart of gold
From the Adair Lab, Clinical Research Division
Engineering B cells to bypass vaccines
From the Taylor Lab, Vaccine and Infectious Disease Division
Special delivery: Gold nanoparticles ship CRISPR cargo
Fred Hutch scientists used their new golden courier to edit genes tied to HIV, genetic blood disorders
Could gold be the key to making gene therapy for HIV and other blood disorders more accessible?
A proof-of-principle study published in Nature Materials shows that gold nanoparticles loaded with CRISPR and other gene-editing tools safely and effectively edited blood stem cells. (Photos, diagram available for media use.)