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Nanoparticles with a mega impact: how injectable mRNA fights cancer
From the Stephan Lab and Nelson Lab, Cancer Immunology Program, Cancer Consortium
Nanoreagents for improving inflammation in auto-immune disease
From the Stephan Lab, Clinical Research Division
Investment in business development pays dividends for research, patients
Fred Hutch tech transfer specialists help scientists navigate path to bringing innovations to patients
Fred Hutch research a GeekWire Award finalist for Health Innovation of the Year
Other finalists include Fred Hutch spinoffs Adaptive Biotechnologies and Blaze Bioscience
Scientists show thin metal mesh loaded with T cells shrinks solid tumors
Within weeks, CAR T cells targeting ovarian cancer cleared tumors in 70% of treated mice, shows study in Nature Biomedical Engineering. (Note: Images available for media use.)
Cancer immunotherapy gets assist from micro-scale engineering
With new molecular 'handles' and stimulating signals, metallic thin films become a stronghold for cancer-killing immune cells
Reprograming macrophages with nanoparticles
From the Stephan Lab, Clinical Research Division
Nanotech turns pro-tumor immune cells into cancer-killing triple agents
Strategy doubles survival in mice with cancer
Dr. Matthias Stephan named Allen Distinguished Investigator
The $1.5 million award will help translate cutting-edge nanoparticle immunotherapy approach to the clinic
Improving cancer vaccines with T-cell programming nanoparticles
Dr. Matthias Stephan receives grant to develop cancer vaccine–optimizing, TCR-programming nanotechnology
Nanoparticles open doors to cancer-fighting CAR T cells
Tiny liposome-based drug carriers make tumors more vulnerable to targeted immunotherapy
Nanoparticles take immunotherapy in new direction
Hutch scientist to use nanoparticles to reprogram macrophages to tackle brain tumors
10 highlights of Fred Hutch science in 2017
A look back at notable discoveries in cancer immunotherapy, HIV prevention and more
New nanoparticles make targeted, temporary gene therapy possible
‘Hit-and-run’ technology could improve immunotherapy and HIV cure research
Good News: Bezos family funding accelerates glioma immunotherapy research
Celebrating faculty and staff achievements
Dissolving implant could bring immunotherapy to solid tumors
A biopolymer sponge delivers cancer-shrinking T-cell therapy in preclinical study
Implanted scaffold with T cells rapidly shrinks tumors
A biopolymer structure enriched with nutrients shows how immunotherapy could be adapted for solid tumors, according to a study in The Journal of Clinical Investigation.
Tiny tech reprograms immune cells to fight cancer
Nanoparticles turn immune cells into leukemia-fighting powerhouses while they’re still inside the body
Nanoparticles reprogram immune cells to fight cancer
Study in Nature Nanotechnology describes new method to transform immune cells, while inside the body, into leukemia-fighting powerhouses