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Muscleblind proteins revealed to have a new role as anti-tumor agents
From the Bradley lab, Biostatistics and Computational Biology Program and Public Health Sciences and Basic Sciences Divisions. By J Landazuri
RNA “typos” can highlight leukemia cells for immune attack
Looking beyond DNA, scientists find possible “surgically targeted” option for splicing factor-mutant blood cancers that lack effective immunotherapies
From humans, to mice, to plants: sometimes a little poison is a good thing
From The Bradley Lab, Public Health Sciences and Basic Sciences Divisions.
Mutant’s partner in crime could be target for future cancer therapy
Fred Hutch scientists discover a new player — and possible drug target — in a critical biological process that’s skewed in tumors with certain mutations
Gene specific alternative polyadenylation can reduce tumor growth
From the Bradley Lab, Basic and Public Health Sciences Divisions
Circling back to RNA sequencing data to map recursive splice sites
From the Robert Bradley Lab, Public Health Sciences and Basic Sciences Divisions & Cancer Consortium
Hit the “reset” button on acquired drug resistance of cancer cells
From the Bradley Lab, Public Health Sciences and Basic Sciences Divisions and collaborating Abdel-Wahab Lab, Memorial Sloan Kettering Cancer Center
Year in Pictures: 2022
A look back at the year through compelling images
Uncovering cancer growth genes that have each other’s back when the other is down
From the Berger Lab, Human Biology Division
The cell’s two-pronged approach to mitigating genetic errors
From the Bradley Lab, Public Health Sciences and Basic Sciences Divisions
Engaging cancer cells in a high stakes game of spot the imposter
From the Bradley Lab, Public Health Sciences and Basic Sciences Divisions
New therapeutic strategy turns a cancer’s advantage into its downfall
In the lab, researchers use synthetic mRNA to trick tumors into manufacturing cancer-specific poison
Hopes and predictions for 2022
Hutch researchers look ahead to an increase in cancer screening, improved vaccines and greater trust in science
Highlights of Fred Hutch science in 2021
From COVID-19 to cancer, Hutch scientists pursued new ideas to save lives
Dr. Robert Bradley named scientific director of Fred Hutch Translational Data Science Integrated Research Center
Computational biologist will lead efforts to integrate data science in bench-to-bedside cancer research
Tip Sheet: Disparities in cancer outcomes, catching up on cancer screenings, boosting immunotherapy effectiveness and SARS-CoV-2 origins
Summaries of recent Fred Hutch research findings and other news
How RNA-altering drugs might improve anticancer immunotherapies
In lab study, brief disruptions of gene machinery make tumor cells more 'visible' to immune system
Omics made easier
To see the big picture, just add ‘ome’