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Fred Hutch collaboration reveals molecular vulnerability in rare childhood brain cancer
Researchers uncover a weak link in tumors driven by a notorious gene fusion that could be targeted with a drug
Fred Hutch biochemist eavesdrops on cellular debate about where to start translating genetic messages
Study sheds light on how translation start-site selection can go awry in cancer and other diseases
Fred Hutch researchers test privacy-first AI platform for cancer research
After a year of building the infrastructure for its federated learning platform, the Cancer AI Alliance (CAIA) is road-testing eight projects using de-identified clinical data from four comprehensive cancer centers
Glow-tagging the androgen receptor reveals an unexpected vulnerability in advanced prostate cancer
A recent study by a Fred Hutch prostate cancer expert finds potential new drug targets using an innovative tagging method that can be applied to other hormone-driven cancers
Fred Hutch researchers discover an unknown soldier in defense against viruses
A gene better known for its role in cancer progression also plays a surprising role in mounting an immune defense against Zika virus
Brandeis University honors Fred Hutch molecular biologist
Dr. Steven Henikoff receives 55th Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research
Frogs help Fred Hutch find the shape of small things
Dr. Yasuhiro Arimura brings frogs back to Fred Hutch after a long absence to study the structure of DNA-linked molecular complexes that change during the cell cycle and malfunction in cancer and other diseases
Dr. Yeon Soo Kim receives NIH Pathway to Independence Award
Hsieh Lab postdoctoral fellow studies how advanced prostate cancer evades therapy by altering the way RNA builds proteins
Science fair for grown-ups
Poster sessions spark conversation and collaboration
Fred Hutch study finds new life for ‘ineffective’ drugs
Innovative method using more authentic tumor samples reveals untapped potential for drugs written off by more conventional tests
Oh, the microbes you’ll meet!
Fred Hutch Cancer Center immunologist discovers a biological mechanism sprung in the first week of life that trains a mouse pup’s immune system to tolerate harmless gut bugs and new foods
Looking beyond suspect genes in cancer
Fred Hutch is among 10 institutions in the U.S., the U.K. and Europe collaborating to find the function of every protein-coding gene in the human genome
Conducting RNA reconnaissance
Fred Hutch researchers invent a CRISPR screening method to understand RNA-binding proteins often mutated in cancer and other diseases
Virologist and HIV expert Dr. Michael Emerman retires
Emerman considers mentorship his most important duty in science
Mapping molecules of an unsung brain cell
Fred Hutch researchers create a gene-expression map of glial cells in tiny worms, adding the missing component that completes for the first time an atlas of the entire nervous system of a multicellular adult animal at the molecular level
Two Fred Hutch studies identify pancreatic cancer biomarker driving basal disease
Dr. Sita Kugel’s team recently published two papers identifying a key biological signature that not only provides clinics a faster, cheaper way to tell pancreatic cancer subtypes apart, but reveals a biological mechanism that could lead to new therapies
Fred Hutch study finds genetic driver of drug resistance in small cell lung cancer
Researchers use CRISPR-Cas9 gene-editing tool on tumor cells grown in mice to better model how tumors that initially respond to chemotherapy become resistant
Managing mountains of genomic data
Tools invented at Fred Hutch are helping researchers analyze the enormous global database of genomic sequences of the virus that causes COVID-19 to better understand how pathogens evolve and spread
Rewriting the story about the molecules that turn genes on and off
Fred Hutch researchers discover that most transcription factors in budding yeast don’t follow the textbook example of binding close to the genes they regulate
Cell biologist and former Fred Hutch division leader Dr. Jonathan Cooper retires
Cooper sustained the distinct culture of Basic Sciences for four decades