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Brandeis University honors Fred Hutch molecular biologist
Dr. Steven Henikoff receives 55th Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research
Frogs help Fred Hutch find the shape of small things
Dr. Yasuhiro Arimura brings frogs back to Fred Hutch after a long absence to study the structure of DNA-linked molecular complexes that change during the cell cycle and malfunction in cancer and other diseases
Dr. Yeon Soo Kim receives NIH Pathway to Independence Award
Hsieh Lab postdoctoral fellow studies how advanced prostate cancer evades therapy by altering the way RNA builds proteins
Science fair for grown-ups
Poster sessions spark conversation and collaboration
Fred Hutch study finds new life for ‘ineffective’ drugs
Innovative method using more authentic tumor samples reveals untapped potential for drugs written off by more conventional tests
Oh, the microbes you’ll meet!
Fred Hutch Cancer Center immunologist discovers a biological mechanism sprung in the first week of life that trains a mouse pup’s immune system to tolerate harmless gut bugs and new foods
Looking beyond suspect genes in cancer
Fred Hutch is among 10 institutions in the U.S., the U.K. and Europe collaborating to find the function of every protein-coding gene in the human genome
Conducting RNA reconnaissance
Fred Hutch researchers invent a CRISPR screening method to understand RNA-binding proteins often mutated in cancer and other diseases
Virologist and HIV expert Dr. Michael Emerman retires
Emerman considers mentorship his most important duty in science
Mapping molecules of an unsung brain cell
Fred Hutch researchers create a gene-expression map of glial cells in tiny worms, adding the missing component that completes for the first time an atlas of the entire nervous system of a multicellular adult animal at the molecular level
Two Fred Hutch studies identify pancreatic cancer biomarker driving basal disease
Dr. Sita Kugel’s team recently published two papers identifying a key biological signature that not only provides clinics a faster, cheaper way to tell pancreatic cancer subtypes apart, but reveals a biological mechanism that could lead to new therapies
Fred Hutch study finds genetic driver of drug resistance in small cell lung cancer
Researchers use CRISPR-Cas9 gene-editing tool on tumor cells grown in mice to better model how tumors that initially respond to chemotherapy become resistant
Managing mountains of genomic data
Tools invented at Fred Hutch are helping researchers analyze the enormous global database of genomic sequences of the virus that causes COVID-19 to better understand how pathogens evolve and spread
Rewriting the story about the molecules that turn genes on and off
Fred Hutch researchers discover that most transcription factors in budding yeast don’t follow the textbook example of binding close to the genes they regulate
Cell biologist and former Fred Hutch division leader Dr. Jonathan Cooper retires
Cooper sustained the distinct culture of Basic Sciences for four decades
Drs. Keith Jerome and Jesse Bloom elected fellows of American Academy of Microbiology
Fred Hutch researchers’ study of viruses evolves from basic understanding to practical applications
New methods reveal cancer mechanism in ancient genes
Fred Hutch researchers discover that overproduction of DNA packaging material predicts aggressive brain and breast tumors, which could lead to cheaper diagnostic tests and new drug therapies
Evolutionary cell biologist Dr. Grant King named a Hanna Gray Fellow
Long fascinated by life seen and unseen, King awarded eight years of funding to finish postdoctoral training at Fred Hutch and establish an independent lab
Cold air makes oxygen toxic for worms
Fred Hutch study shows C. elegans, a microscopic worm, can survive low temperatures if oxygen supply is also low
Tricking cells into trashing cancer
Fred Hutch chemical biologist rapidly reduces lung tumors in mice with a tagging system that grabs cancer-causing proteins and hauls them out with the molecular trash