Major Collaborations

HIV Vaccine Trials Network (HVTN) designs and conducts all phases of clinical trials around the world, from evaluating experimental HIV/AIDS vaccines and broadly neutralizing antibody (bnAb) infusions for safety and immunogenicity to rigorously testing vaccine and bnAb efficacy. SCHARP has supported the network, which is funded by the National Institutes of Health (NIH), since 1999.

HIV Prevention Trials Network (HPTN) researchers integrate strategies for HIV prevention, including antiretroviral drugs and behavioral risk reduction interventions. This global network evaluates new HIV prevention interventions and strategies in populations and geographical regions that have a high rate of infection. SCHARP has provided data management expertise to HPTN since 1999.

The Vaccine Immunology Statistical Center (VISC) provides biostatistical collaboration to support projects that accelerate discovery for global health. The center brings technical expertise in high-dimensional data analysis, and statistical and machine learning methods that cut across disease foci including tuberculosis, COVID-19, malaria, HIV and others. VISC is funded by the Bill & Melinda Gates Foundation and is part of the Collaboration for AIDS Vaccine Discovery (CAVD). SCHARP partners with VISC on statistical analysis, methods development and lab data management. 

The most common cancers in low- and middle-income countries are associated with infectious diseases including HIV, human papillomavirus (HPV) and viral hepatitis. SCHARP supports a research study in Uganda through the Fred Hutch Global Oncology program, whose mission is to reduce cancer around the world and help people who are most vulnerable through improved diagnosis, better prevention strategies and optimized treatment plans. SCHARP frequently partners with clinical research collaborators around the world to publish critical study results. 

The Centers for Disease Control and Prevention’s Division of STD Prevention (DSTDP) launched the Sexually Transmitted Infections Impact Research Consortium (STIIRC) to provide research, scientific and technical expertise to increase the population-level impact of STI prevention and control through public health programs and improve health equity for populations disproportionately affected by STI. SCHARP serves as the Data Coordinating Center in partnership with the University of Washington.

The Infectious Disease Clinical Research Consortium (IDCRC) works through a flexible, sustaining structure to advance new countermeasures and approaches to product development, implement efficient clinical study/trial designs, promote the integration of special and underserved populations in IDCRC research across the human lifespan. The IDCRC also supports exceptional career development and mentoring of future leaders in infectious diseases clinical research. SCHARP supports the IDCRC’s Statistical and Data Science Unit.