2026 |
2026
Yan Y, Chen W, Ge X, Sun J, Yu L, Garcia-Mansfield K, Zhang X, Yu Y, Xiong W, Zou D, An G, Jia Z, Pirrotte P, Li JJ, Yu Z, Hao M, Qiu L, Qi J, Wang L, Yi S. Proteogenomic features define subtypes of mantle cell lymphoma. Blood Adv. 2026 Mar 5:bloodadvances.2025018701. doi: 10.1182/bloodadvances.2025018701. Epub ahead of print. PMID: 41785305.
Dong, C.Y., Cen, Y., Song, D., and Li, J.J. (2026). scDesignPop generates realistic population-scale single-cell RNA-seq for power analysis, benchmarking, and privacy protection. bioRxiv.
Cai Y, Surapaneni A, Vasconcelos AG, Johnson M, Hsu L, Sun W, Kooperberg C, Yu B, Yeo WJ, Auer PL, Grams ME, Franceschini N, Raffield LM, Reiner AP. Alterations of Plasma Metabolites Associated with Sickle Cell Trait. Clin J Am Soc Nephrol. 2026 Feb 27. doi: 10.2215/CJN.0000001015. Epub ahead of print. PMID: 41758580.
Booth A, Hillman S, Laumann K, Zhao YQ, LeBlanc M, Chansky K, Giri S, Dill J, Johnson J, Kelley K, Martin L, Osarogiagbon RU, Morris MJ, Chiang AC, Kozono DE, Blanke CD, Galanis E, Gray JE, Stinchcombe TE, Aljumaily R, Morgensztern D, Mandrekar SJ. PROSPECT-LUNG: A National Clinical Trials Network Trial Advancing Pragmatic Innovation in Cancer Clinical Trials. J Thorac Oncol. 2026 Feb 24:103650. doi: 10.1016/j.jtho.2026.103650. Epub ahead of print. PMID: 41747891.
Singal AG, Jin Q, Marrero J, Parikh ND, Lok AS, Lopez C, Page-Lester S, Roberts LR, Reddy R, Luster M, Khaderi S, Asrani SK, El-Serag HB, Kanwal F, Feng Z, Tayob N. Validation of longitudinal biomarker screening algorithms for HCC detection in patients with cirrhosis. Hepatol Commun. 2026 Feb 19;10(3):e00902. doi: 10.1097/HC9.0000000000000902. PMID: 41730232; PMCID: PMC12922931.
Brück CC, Mwangi LW, van Wifferen F, Hsu L, Thomas M, Peters U. Risk-based screening for early detection of colorectal cancer: an overview. Best Pract Res Clin Gastroenterol. 2026 Feb;80:102014. doi: 10.1016/j.bpg.2025.102014. Epub 2025 May 8. PMID: 41724531.
Eyrich NW, Huang Y, Zheng Y, Wei J, Sokoll L, Chan DW, Patil D, Chinnaiyan A, Tomlins SA, Lotan Y, Lin D, Scherr D, Wang Y, Kibel A, Taneja SS, Bidair M, Thompson IM, Sanda MG, Narayan VM. Combining Serum Prostate Health Index With Urinary PCA3 and TMPRSS2:ERG RNA Testing Improves Detection of Clinically Significant Prostate Cancer. JU Open Plus. 2026 Feb 19;4(2):e00019. doi: 10.1097/JU9.0000000000000425. PMID: 41709952; PMCID: PMC12911490.
Tjader NP, Ramroop J, Gandhi T, Dauch C, Meadows O, Stevens P, Pearlman R, Hampel H, Aglago EK, Berndt SI, Bloomer A, Brenner H, Buchanan DD, Campbell PT, Cao Y, Chan AT, Cheng I, Dimou N, Drew DA, French AJ, Georgeson P, Giannakis M, Giles GG, Gomez M, Gruber SB, Hoffmeister M, Huang WY, Hullar MAJ, Huyghe JR, Loroña N, Moreno V, Newton CC, Nowak JA, Obón-Santacana M, Ogino S, Pellatt A, Peoples AR, Permuth JB, Schmit SL, Schoen RE, Siegel EM, Steinfelder RS, Sun W, Teer JK, Thomas CE, Trinh QM, Tsilidis K, Ugai T, Um CY, Van Guelpen B, Zaidi SH, Figueiredo J, Peters U, Phipps AI, McElroy JP, Toland AE. Association of germline variants with KRAS-mutation status in colorectal cancer. Sci Rep. 2026 Feb 13. doi: 10.1038/s41598-026-39644-8. Epub ahead of print. PMID: 41688657.
LaMonte MJ, Hyde ET, Nguyen S, Castro E, Seguin-Fowler RA, Eaton CB, Miller CR, Di C, Stefanick ML, LaCroix AZ. Muscular Strength and Mortality in Women Aged 63 to 99 Years. JAMA Netw Open. 2026 Feb 2;9(2):e2559367. doi: 10.1001/jamanetworkopen.2025.59367. PMID: 41686437; PMCID: PMC12905654.
Kanwal F, Lopez C, Ning J, Luster M, Reddy KR, Parikh ND, Singal AG, Marrero JA, Chhatwal J, Feng Z, Page-Lester S, Koay EJ, El-Serag HB. Validation of THCC-RI in the Hepatocellular Carcinoma Early Detection Strategy (HEDS) Study. Clin Gastroenterol Hepatol. 2026 Feb 9:S1542-3565(26)00070-4. doi: 10.1016/j.cgh.2026.01.041. Epub ahead of print. PMID: 41672261.
Hill CM, Malen RC, Reedy AM, Kahsai O, Curtis K, Ma N, Randolph TW, Ma J, Thomas CE, Ogino S, Potter JD, Buchanan DD, Newcomb PA, Hullar MAJ, Phipps AI. Associations of epidemiologic risk factors with Fusobacterium nucleatum and bacterial alpha diversity in the colorectal tumor-associated microbiota. Cancer Causes Control. 2026 Feb 10;37(3):45. doi: 10.1007/s10552-026-02133-4. PMID: 41665694; PMCID: PMC12891059.
Peoples AR, Obón-Santacana M, Kim AE, Kawaguchi ES, Fu Y, Qu C, Moratalla-Navarro F, Morrison J, Lin Y, Arndt V, Berndt SI, Bien SA, Bishop DT, Bouras E, Brenner H, Buchanan DD, Campbell PT, Chan AT, Chang-Claude J, Conti DV, Corley DA, Devall MA, Dimou N, Drew DA, Gruber SB, Gunter MJ, Harlid S, Harrison TA, Hoffmeister M, Hsu L, Huyghe JR, Keku TO, Kundaje A, Lewinger JP, Li L, Lynch BM, Le Marchand L, Martín V, Murphy N, Newton CC, Ogino S, Hardikar S, Ose J, Pai RK, Palmer JR, Papadimitriou N, Pardamean B, Pellatt AJ, Pinchev M, Platz EA, Potter JD, Rennert G, Ruiz-Narvaez EA, Sakoda LC, Schoen RE, Shcherbina A, Stern MC, Su YR, Thomas CE, Tian Y, Tsilidis KK, Um CY, van Duijnhoven FJB, Van Guelpen B, Visvanathan K, Wang J, White E, Wolk A, Woods MO, Wu AH, Ulrich CM, Peters U, Gauderman WJ, Moreno V. Genetic risk factors modulate the association between physical activity and colorectal cancer. BMC Med. 2026 Feb 5. doi: 10.1186/s12916-026-04675-5. Epub ahead of print. PMID: 41645200.
Xiong Y, Chan KCG, Gorfine M, Hsu L. Assessing the Benefits and Burdens of Preventive Interventions. Stat Med. 2026 Feb;45(3-5):e70410. doi: 10.1002/sim.70410. PMID: 41641624. Samorodnitsky S, Campbell K, Little A, Ling W, Zhao N, Chen YC, Wu MC. Detecting clinically relevant topological structures in multiplexed spatial proteomics using TopKAT. Patterns (N Y). 2026 Jan 9;7(1):101456. doi: 10.1016/j.patter.2025.101456. PMID: 41583981; PMCID: PMC12827733.
Montgomery B, Lynch JA, Brown J, Maxwell KN, Teerlink CC, Kabilovic N, Stoll K, Simon J, Kogan M, Hassan S, Whitbourne SB, Muralidhar S, Schoen MW, Ramoni R, Gaziano JM, Sokolova AO, Cheng HH, Etzioni R, Pritchard CC. Remote delivery of cancer genetic testing in veterans with metastatic prostate cancer: A Million Veteran Program pilot study. Cancer. 2026 Feb 1;132(3):e70283. doi: 10.1002/cncr.70283. PMID: 41615269; PMCID: PMC12857595.
Kendra KL, Bellasea SL, Eroglu Z, Hu-Lieskovan S, Campbell KM, Carson WE 3rd, Wada DA, Plaza JA, In GK, Ikeguchi A, Hyngstrom J, Brohl AS, Chmielowski B, Khushalani NI, Markowitz J, Monroe M, Contreras CM, Bowles T, Norman K, Medina E, Gonzalez CR, Baselga-Carretero I, Garcilazo IP, Vega-Crespo A, Chen JM, Deen NNA, Patel SP, Grossmann KF, Sondak VK, Sharon E, Moon J, Wu MC, Ribas A. Neoadjuvant PD-1 blockade in surgically resectable desmoplastic melanoma: cohort A of the phase 2 SWOG S1512 trial. Nat Cancer. 2026 Feb;7(2):272-282. doi: 10.1038/s43018-025-01113-y. Epub 2026 Jan 29. PMID: 41611998; PMCID: PMC12948668.
Pareek E, Pershad Y, Zhao K, Uddin MM, Xue L, Vlasschaert C, Mack TM, Haessler J, Collins JM, Glick E, Glaser V, Heise R, Ling W, Haring B, Shadyab A, Beydoun H, Wallace R, Jaiswal S, Manson JE, Natarajan P, Honigberg MC, Kooperberg C, Whitsel EA, Kitzman JO, Bick AG, Reiner AR, Desai P. Metformin does not significantly alter longitudinal dynamics of clonal hematopoiesis. Clin Cancer Res. 2026 Jan 28. doi: 10.1158/1078-0432.CCR-25-3606. Epub ahead of print. PMID: 41603726.
Samorodnitsky S, Campbell K, Little A, Ling W, Zhao N, Chen YC, Wu MC. Detecting clinically relevant topological structures in multiplexed spatial proteomics using TopKAT. Patterns (N Y). 2026 Jan 9;7(1):101456. doi: 10.1016/j.patter.2025.101456. PMID: 41583981; PMCID: PMC12827733.
Chen Z, Song W, Li Q, Li C, Wen W, Huyghe JR, Law PJ, Fernandez-Rozadilla C, Timofeeva MN, Thomas M, Schmit SL, Martin V, Devall M, Dampier C, Moratalla-Navarro F, Cai Q, Wang J, Shi J, Kweon SS, Tanikawa C, Jia WH, Shu X, Long J, Gao J, Kim J, Shin A, Matsuo K, Jee SH, Jung KJ, Wang N, Kim DH, Ping J, Yang G, Shin MH, Ren Z, Oh JH, Oze I, Ahn YO, Gao YT, Pan ZZ, Kamatani Y, Van Kaer L, Wu L, Li B, Matsuda K, Shu XO, Hsu L, Dunlop MG, Gruber SB, Houlston R, Tomlinson I, Li L, Lau KS, Moreno V, Casey G, Peters U, Zheng W, Guo X. Mixed-model and transcriptome-wide association analyses identify transcription factors and genes associated with colorectal cancer susceptibility. Nat Commun. 2026 Jan 15;17(1):1377. doi: 10.1038/s41467-025-68127-z. PMID: 41540004; PMCID: PMC12877115.
Brzoska T, Kaminski TW, Katoch O, Menchikova EV, Alagbe AE, Tashbook SE, Tofovic SP, Jonassaint JC, St Croix CM, Watkins SC, Howe S, Field JJ, Seyerle AA, Pradhan-Sundd T, Laurie C, Pankratz ND, Smith NL, Goode EL, Pankow JS, Kooperberg C, Kato GJ, Zhang Y, Novelli EM, Gladwin MT, Jackson EK, Nouraie SM, Sundd P. CD39 polymorphism enables lung thrombosis in sickle cell disease. Nat Commun. 2026 Jan 14;17(1):1693. doi: 10.1038/s41467-026-68396-2. PMID: 41530145; PMCID: PMC12909804.
Johnson M, Cai Y, Vasconcelos AG, Orchard P, Auer PL, Lettre G, Wen J, Franceschini N, Kooperberg C, Sun W, Hsu L, Raffield LM, Reiner AP. Whole Blood Transcriptomic Analysis of Sickle Cell Trait. Eur J Haematol. 2026 Jan 13. doi: 10.1111/ejh.70114. Epub ahead of print. PMID: 41528117.
Liu D, Song B, Li Z, Zhang S, Fabiha T, Zhao J, Inoki A, Piccand J, Soh CL, Dixon G, Zhong A, Hu N, Luo R, Ozlusen B, Menon V, Zhou T, Qiu X, Gradwohl G, Yang D, Dey K, Sun W, Li W, Huangfu D. A stem cell knockout village reveals lineage rewiring and a non-canonical islet cell fate in monogenic diabetes. bioRxiv [Preprint]. 2025 Dec 25:2025.12.23.696311. doi: 10.64898/2025.12.23.696311. PMID: 41509490; PMCID: PMC12776134.
Werwath KE, Lawn RB, Salem MT, Li T, Mitchell BL, Shen H, Gordon SD, Kung B, Stafford C, Vemuri M, Ratanatharathorn A, Meijsen J, Shadyab AH, Kooperberg C, Koenen KC, Crandall CJ, Martin NG, Duncan LE. Trans-ancestry GWAS of hot flashes reveals potent treatment target and overlap with psychiatric disorders. Commun Med (Lond). 2026 Jan 6;6(1):51. doi: 10.1038/s43856-025-01305-8. PMID: 41495267; PMCID: PMC12830824.
Van Buren E, Zhang Y, Li X, Selvaraj MS, Li Z, Zhou H, Palmer ND, Arnett DK, Blangero J, Boerwinkle E, Cade BE, Carlson JC, Carson AP, Chen YI, Curran J, Duggirala R, Fornage M, Franceschini N, Graff M, Gu C, Guo X, He J, Heard-Cosa N, Hou L, Hung YJ, Kalyani RR, Kardia SLR, Kenny E, Kooperberg C, Kral BG, Lange L, Levy D, Li C, Liu S, Lloyd-Jones D, Loos RJF, Manichaikul AW, Martin LW, Mathias R, Minster RL, Mitchell BD, Mychaleckyj JC, Naseri T, North K, O'Connell J, Perry JA, Peyser PA, Psaty BM, Raffield LM, Vasan RS, Redline S, Reiner AP, Rich SS, Smith JA, Spitzer B, Tang H, Taylor KD, Tracy R, Viali S, Yanek L, Zhao W; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Rotter JI, Peloso GM, Natarajan P, Lin X. cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions. Nat Methods. 2026 Feb;23(2):338-349. doi: 10.1038/s41592-025-02919-5. Epub 2025 Dec 31. PMID: 41476111.
Li B, Lin R, Ni T, Yan G, Burns M, Li JJ, Yao Z. CellScope: high-performance cell atlas workflow with tree-structured representation. Nat Commun. 2025 Dec 30;17(1):1130. doi: 10.1038/s41467-025-67890-3. PMID: 41469386; PMCID: PMC12855844.
Harrison TA, Zaidi SH, Yin H, Steinfelder RS, Qu C, Aglago EK, Berndt SI, Boardman LA, Brenner H, Buchanan DD, Campbell PT, Cao Y, Chan AT, Chanock SJ, Doheny KF, Drew DA, Figueiredo JC, French AJ, Gallinger S, Georgeson P, Giannakis M, Goode EL, Gruber SB, Gsur A, Gunter MJ, Harlid S, Hoffmeister M, Huang WY, Hullar MA, Huyghe JR, Jenkins MA, Lin Y, Moreno V, Murphy N, Newcomb PA, Newton CC, Nowak JA, Obón-Santacana M, Ogino S, Shelford T, Song M, Thomas CE, Toland AE, Ugai T, Um CY, Van Guelpen B, Trinh QM, Sun W, Hudson TJ, Hsu L, Peters U, Phipps AI. Genomic characterization of colorectal tumors: insights into significantly mutated genes, pathways, and survival outcomes. BMC Cancer. 2025 Dec 18;26(1):109. doi: 10.1186/s12885-025-15440-x. PMID: 41413856; PMCID: PMC12831426.
Sevilla-González M, Wang N, Hanson PA, Bebo A, Hitchcock D, Hsu S, Westerman KE, Cromer SJ, Barry VG, Borns-Weil Y, Zhang Y, Ben-Yossef O, Patel CJ, Franceschini N, Taylor KD, Ávila-Pacheco J, Clish CB, Gertzen RE, Raffield LM, Kooperberg C, Rich SS, Dupuis J, Rotter JI, Liu CT, Meigs JB, Manning AK. Dissecting Genetic and Environmental Determinants of Plasma Molecular Signatures and Their Link to Type 2 Diabetes Risk. medRxiv [Preprint]. 2025 Nov 28:2025.11.26.25341007. doi: 10.1101/2025.11.26.25341007. PMID: 41358287; PMCID: PMC12676399.
Ferrier K, Graff M, Konigsberg IR, Stanislawski M, Highland HM, Raffield LM, Carson AP, Boerwinkle E, Norris JM, Gignoux CR, Hendricks AE, Raghavan S, North KE, Young KL, Justice AE, Allison MA, Budoff MJ, Kasela S, Aguet F, Joseph JJ, Kooperberg C, Rich SS, Rotter JI, Lange EM, Lange LA. Epigenome-wide association study meta-analysis of BMI in African Americans. HGG Adv. 2026 Jan 15;7(1):100552. doi: 10.1016/j.xhgg.2025.100552. Epub 2025 Dec 4. PMID: 41351263; PMCID: PMC12903085.
Perkins RB, Wolf AMD, Church TR, Elkin EB, Skates SJ, Etzioni RD, Guerra CE, Herzig A, Hoffman RM, Oeffinger KC, Raoof S, Shih YT, Walter LC, Zeigler-Johnson C, Manassaram-Baptiste D, Smith RA. Self-collected vaginal specimens for human papillomavirus testing and guidance on screening exit: An update to the American Cancer Society cervical cancer screening guideline. CA Cancer J Clin. 2026 Jan-Feb;76(1):e70041. doi: 10.3322/caac.70041. Erratum in: CA Cancer J Clin. 2026 Jan-Feb;76(1):e70066. doi: 10.3322/caac.70066. PMID: 41342729; PMCID: PMC12677112.
Zhao LP, Papadopoulos GK, Skyler JS, Parikh HM, Kwok WW, Lybrand TP, Bondinas GP, Moustakas AK, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark Å. Profiling Associations Between IGHG-FCGR Ligand-Receptor Interactions and Disease Progression From Stage 1 and 2 to Stage 3 Type 1 Diabetes. Diabetes. 2026 Jan 20;75(2):379-388. doi: 10.2337/db25-0610. PMID: 41335420; PMCID: PMC12823336.