/etc.clientlibs/common/clientlibs/resources/svg/provider-directory.svg
Test
Complete Physician Template, MD
Top Doctor icon

Complete Physician Template, MD

  • Medical Director, Cellular Immunotherapy and Bezos Family Immunotherapy Clinic, Fred Hutch
  • Professor of Medicine, Division of Oncology, University of Washington
  • Professor and Medical Director Cellular Immunotherapy, Clinical Research Division, Fred Hutch
  • Leonard and Norma Klorfine Endowed Chair for Clinical Research, Fred Hutch

Medical Oncology

About

Dr. First Last name cupcake marzipan icing marshmallow sesame snaps. Cupcake toffee pudding donut candy pie chupa chups jelly icing. Chocolate chocolate bar candy carrot cake oat cake. Jujubes jelly beans tootsie roll chocolate cake cupcake. Danish soufflé cheesecake caramels donut biscuit tootsie roll.


Provider Background

As the medical director of the Bezos Family Immunotherapy Clinic at Fred Hutch, I treat patients with lymphoid cancers, such as chronic lymphocytic leukemia (CLL), non-Hodgkin lymphoma and multiple myeloma. My expertise spans the use of antibodies (proteins in the immune system that fight invaders), vaccines and bone marrow transplants. In the 1990s, I led the development of the drug rituximab, the first antibody-based cancer treatment, and I was also part of the team that created the mini-transplant, a less intense form of the conventional stem cell transplant.

Today, my research is focused on developing new immunotherapies where a patient’s own T cells (immune cells) are modified with a molecule called a chimeric antigen receptor (CAR). This receptor directs a patient’s immune system to attack tumors. Known as CAR T-cell therapy, this approach has been remarkably effective in early-phase trials, even with very advanced cancers that resist other treatments.

Area of Clinical Practice
Adult blood and marrow transplantation, cellular immunotherapy, hematologic malignancies


“It’s not enough to treat cancer — we want to rev up your immune system to cure it.”

— Dr. Maloney


Why do you conduct research?

When I was a student at Stanford University in the 1980s, I was part of a team that made an amazing discovery. We created a protein called a monoclonal antibody that targeted cancer cells without harming healthy ones. At the time, there were a lot of skeptics — most people thought that antibody research wasn’t worthwhile. But we persevered, and now monoclonal antibodies are an important part of therapy for a variety of cancers. That breakthrough made me hungry for more. What else could I discover about the immune system? Could we train it to go after tumors the same way it attacks viruses? Does it hold the key for curing cancer, once and for all? These are the questions that have driven my work.

How do you approach cancer treatment?

A treatment plan isn’t something that we devise in one short discussion. It’s an in-depth conversation that may stretch across multiple visits. We’ll consider factors such as your health, your age, your disease, your personal philosophy and what the latest research has to offer. Treatments are rapidly evolving, and I enjoy sharing these advances with you so that you can make the best decisions about your care. Whatever you choose, I’m dedicated to helping you achieve the best possible outcome.

Diseases Treated

Languages

English

Education and Experience

Fellowship, Focus, Institution

Residency, Focus, Institution

MD, 

XX, 

Board Certifications

Medical Oncology 2019; Internal Medicine, 1988; American Board of Internal Medicine

Awards

Seattle Met's 2019 Top Doctors award
Dr. Maloney has been recognized as a Top Doctor in Seattle Met's annual survey multiple years in a row.

Clinical Trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch physicians. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your physician can decide if a study is right for you.

View Clinical Trials

Publications

Many of our Fred Hutch physicians conduct ongoing research to improve standards of patient care. Their work is evaluated by other physicians and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch physician has written.

View Dr. Maloney's Publications

Your Care Team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes physicians, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like registered dietitians, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders.

Insurance

Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.