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Conducting RNA reconnaissance
Fred Hutch researchers invent a CRISPR screening method to understand RNA-binding proteins often mutated in cancer and other diseases
Virologist and HIV expert Dr. Michael Emerman retires
Emerman considers mentorship his most important duty in science
Mapping molecules of an unsung brain cell
Fred Hutch researchers create a gene-expression map of glial cells in tiny worms, adding the missing component that completes for the first time an atlas of the entire nervous system of a multicellular adult animal at the molecular level
Fred Hutch study finds genetic driver of drug resistance in small cell lung cancer
Researchers use CRISPR-Cas9 gene-editing tool on tumor cells grown in mice to better model how tumors that initially respond to chemotherapy become resistant
Managing mountains of genomic data
Tools invented at Fred Hutch are helping researchers analyze the enormous global database of genomic sequences of the virus that causes COVID-19 to better understand how pathogens evolve and spread
Rewriting the story about the molecules that turn genes on and off
Fred Hutch researchers discover that most transcription factors in budding yeast don’t follow the textbook example of binding close to the genes they regulate
Cell biologist and former Fred Hutch division leader Dr. Jonathan Cooper retires
Cooper sustained the distinct culture of Basic Sciences for four decades
Evolutionary cell biologist Dr. Grant King named a Hanna Gray Fellow
Long fascinated by life seen and unseen, King awarded eight years of funding to finish postdoctoral training at Fred Hutch and establish an independent lab
Tricking cells into trashing cancer
Fred Hutch chemical biologist rapidly reduces lung tumors in mice with a tagging system that grabs cancer-causing proteins and hauls them out with the molecular trash
50 years of doing hard things
Founded in 1975 to honor a brother, Fred Hutch Cancer Center pursued bold science, pioneered a cure for blood diseases that changed medicine and became a world-class biomedical research and clinical care institution
Blocking a cancer escape hatch
Fred Hutch graduate student wins NIH F31 award to study structure of a key protein that helps blood vessels grow, but also helps cancer spread when it malfunctions
Cracking the sparkle code
Fred Hutch cancer biologist wins V Foundation Scholar Award to explore role of protein sugaring in leukemia tumors that survive chemotherapy
Making the most of a small supply
Fred Hutch researchers receive $1.3 million grant from the U.S. Department of Defense to study the fundamental biology of five rare liver cancers that could lead to new treatments one day
Fred Hutch launches Atlas of Inspiring Hispanic/Latinx Scientists
Online atlas recognizes contributions of Hispanic and Latinx scientists
Priming the pump for future funding
Fred Hutch postdoctoral researchers win NIH training fellowship for pancreatic cancer and kinetochore projects
Cell biologist Dr. Susan Parkhurst named 2024 ASCB fellow
Fred Hutch researcher honored by American Society for Cell Biology discusses integrating generations of scientists through mentorship
Curiosity, connection and C. elegans
How a Fred Hutch worm study gives hope to families affected by an extremely rare genetic disorder
More to brain tumors than meets the eye
Fred Hutch researchers find new way to classify tumors based on their underlying biology rather than how they look
Another look at leptin
Fred Hutch researchers discover molecular switch for an appetite-regulating hormone, reviving dashed hopes for an obesity drug
The ins and outs of calcium during wound healing
From the Parkhurst Lab, Basic Sciences Division