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Big gains in bone marrow transplant survival since mid-2000s
Despite older, sicker patients, mortality rate dropped by one-third within 10-year period
New Science Spotlight Articles
Every month, Fred Hutch postdoc writer/editors summarize two papers from each of our scientific divisions to stimulate collaborations across campus
January 20, 2020
HLA-B leader sequences influence graft-versus-host-disease
From the Petersdorf laboratory, Clinical Research Division
Antiviral immunity survives CD19-directed therapy
From the Hill and Turtle laboratories, Vaccine and Infections Disease Division and Clinical Research Division
Science on the horizon
Fred Hutch experts make predictions for science trends, advances in 2020
Fred Hutch science and research highlights 2019
Articles showcasing some of the most significant advances in immunotherapy, cell biology and more
Study links common immune cell to failure of checkpoint inhibitors in lung cancer
New research suggests how to better predict which patients will respond to immunotherapy
What's new in breast cancer research: #SABCS19 edition
Fred Hutch researchers share long-term follow-up data on WHI hormone study, anti-hormone side-effect strategies and more at San Antonio meeting
New CAR T cells with synthetic ankyrin repeats
From the Riddell Laboratory, Clinical Research Division
Targeting renal cell carcinoma with transgenic T cell therapy
From the Tykodi and Warren laboratories, Clinical Research Division
Scientists show thin metal mesh loaded with T cells shrinks solid tumors
Within weeks, CAR T cells targeting ovarian cancer cleared tumors in 70% of treated mice, shows study in Nature Biomedical Engineering. (Note: Images available for media use.)
Gimme shelter: CRISPR hides healthy cells from leukemia drug
In mouse study, gene-edited cells stay safe as immunotherapy attacks cancer
Cancer immunotherapy gets assist from micro-scale engineering
With new molecular 'handles' and stimulating signals, metallic thin films become a stronghold for cancer-killing immune cells
Try, try again: Can a 2nd dose of CAR T cells succeed when the first fails?
First-of-its-kind study offers early indication of factors linked to increased odds of success for patients out of options
World AIDS Day: Stepping up the search for a cure
New funding from Gates Foundation and NIH give vote of confidence for an audacious goal
'Keeping these out of the hands of adolescents is critical'
Fred Hutch lung cancer expert testifies as Washington state weighs flavored vaping ban
GM-CSF potentiates acute graft-versus-host-disease
From the Hill lab, Clinical research Division
For the best stem cells, mimic their native niche
By the Delaney lab, Clinical Research Division
Public health throws shade on tanning, and it works
New study shows sharp drop in melanoma rates in people under 30, but skin cancer rates still going up in those over 40
Targeting metastatic breast cancer with CAR T-cell immunotherapy
$4M 'Breakthrough' award funds collaborative research aimed at destroying dormant disseminated tumor cells
Scientists discover new process shaping red blood cell development
Finding could shed new light on causes of certain cancers, anemias