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Giving CAR T cells a portable pit crew
Fred Hutch scientists dig deep into the biology of CAR T-cell exhaustion and examine experimental strategy to improve the immunotherapy for solid tumors
New long-term analysis suggests follicular lymphoma can be cured
The findings could change patient and provider expectations and influence how patients are followed after treatment
Dr. Elizabeth Halloran, expert in vaccine trial design and quantitative methods for infectious diseases, transitions to emerita
Infectious disease modeling pioneer helped outline modern precepts for design and analysis of vaccine trials, causal inference with interference; shaped a generation of infectious disease scientists
The benefits of HIV research? Let us count the ways
HIV work has helped shape the FDA, provided drugs for other infections, changed health systems globally and more, say Fred Hutch experts
‘I can’t remember the last time I saw someone with bad gut GVHD’: BMT expert reflects on recent lifesaving successes
Fred Hutch bone marrow transplant and GVHD expert Dr. Geoffrey Hill explains how a new approach has changed the BMT landscape, where research is headed next
Scientists see foam as starting point of a path to bedside gene therapy
Bioengineer Dr. Matthias Stephan developed a quick-foaming solution that he hopes could one day turn gene therapy into an outpatient procedure
Viral immunologist taps ‘incredible potential’ of immune system
Dr. Paul Thomas will combine computational and empirical approaches to understand the immune repertoire and turn this knowledge into new diagnostic and therapeutic tools
Two lifetimes’ worth of bone marrow transplant breakthroughs
Bone marrow transplant pioneer Dr. Rainer Storb retires and reflects on six decades of science and mentorship
New horizons in infectious disease treatment and prevention in immunocompromised patients
The 5th Symposium on Infectious Disease in the Immunocompromised Host emphasized new opportunities, next generation
Dr. Peter Gilbert receives Marvin Zelen Leadership Award in Statistical Science
Award recognizes leadership in HIV vaccine trial development, analysis
RNA “typos” can highlight leukemia cells for immune attack
Looking beyond DNA, scientists find possible “surgically targeted” option for splicing factor-mutant blood cancers that lack effective immunotherapies
Drs. Keith Jerome and Jesse Bloom elected fellows of American Academy of Microbiology
Fred Hutch researchers’ study of viruses evolves from basic understanding to practical applications
Crunching the numbers for next-gen COVID-19 vaccines
BARDA taps Fred Hutch biostatisticians to assess new vaccine technology, more nimble trial design
‘Action and progress link our globe’
HVTN’s Dr. Daniel Driffin focused on hope in remarks at White House World AIDS Day event
How protective antibodies get in malaria’s way
Fred Hutch researchers’ structural insights help reveal weak spot in parasite’s mode of attack, could guide vaccine design
Laying the groundwork for a new cancer-preventive vaccine
Fred Hutch scientists garner large NCI award to uncover secrets of immune response to virus behind Kaposi sarcoma
Going straight to the source in defense against infant RSV
New anti-idiotype antibody a first step in possible strategy to build infant immunity during vulnerable window
Infectious disease experts propose trials network dedicated to immunocompromised patients
ImmunOptimize workshop convened stakeholders across disciplines to brainstorm infectious disease clinical trials network designed to serve people with weakened immune systems
Engineered HSV can trigger genetic chain reaction, rejigger HSV genes during co-infection
Proof-of-concept work raises hope that ‘gene drive’ could one day form basis of curative gene therapy for herpes
Jennifer Doudna: ‘Curiosity-driven, fundamental science’ underpins Nobel Prize-winning work
CRISPR pioneer spoke at inaugural Fred Hutch President’s Seminar, outlined goals for gene-editing technology