Pathogen-Associated Malignancies Integrated Research Center (PAM-IRC)

Pathogen-Associated Malignancies Integrated Research Center

Advancing cures for cancers caused by pathogens

Each year, 14 million people worldwide are diagnosed with cancer, and up to 20 percent of those cancers are caused, directly or indirectly, by viruses and other pathogens.

At Fred Hutch, our goal is to lead the way in eliminating that burden — and to advance cures for all cancers — through our Pathogen-Associated Malignancies Integrated Research Center.

Led by Dr. Denise Galloway, the Pathogen-Associated Malignancies IRC brings together Hutch experts in infectious diseases, host-pathogen interactions, cancer biology, immunology, global oncology and immunotherapy to understand, treat and prevent the cancers linked to infectious agents.

Fred Hutch researchers excel at understanding the biology of pathogen-related cancers, identifying the immune system’s interaction with both pathogens and cancers, and leveraging that knowledge to develop and test innovative strategies that improve care for patients worldwide. The Pathogen-Associated Malignancies IRC builds on those strengths, interfacing closely with other programs, including our Immunotherapy IRC and Fred Hutch Global Oncology.

Over the next year this IRC will focus on seven infectious pathogens (shown in bold in the graphic below) and their related cancers. The center plans to engage other public and private organizations in a global collaborative effort to reduce the number of cancer cases associated with pathogens.


Dr. Denise Galloway, Director, Pathogen-Associated Malignancies IRC