Fred Hutch researchers excel at understanding the biology of pathogen-related cancers, identifying the immune system’s interaction with both pathogens and cancers, and leveraging that knowledge to develop and test innovative strategies that improve care for patients worldwide. The PAM IRC builds on those strengths, interfacing closely with other programs, including our Immunotherapy and Translational Data Sciences IRCs, and our Global Oncology, Cancer Prevention, Epidemiology and Cancer Basic Biology Programs.
Helicobacter pylori infection is one of the strongest risk factors for gastric cancer and is also more rarely linked to a type of lymphoma. The makeup of our microbiome and diet may also play a role in the formation of colorectal cancer. Our scientists are working to understand how the bacteria in our stomach and intestinal tract can influence the development of cancer or response to therapies. We aim to develop better ways to prevent cancer formation, detect cancer and identify patients at high risk of developing cancer, and explore new ways to treat bacterially associated cancers.