The genomics team, in partnership with our bioinformatics colleagues, provides end-to-end support of Illumina next-generation sequencing projects. Our integrated resources are here for you every step of the way, from experimental design to library prep and downstream analysis.
The sequencers we have to support this work include an Illumina NovaSeq 6000, three NextSeq 2000s, and three MiSeqs. We offer a multitude of library preps including, but not limited to, bulk RNA-seq, single-cell RNA-seq (10x Genomics), RNA exome, polysome profiling, whole exome and whole genome sequencing, cell-free DNA, and targeted amplicon sequencing.
We also offer Cleavage Under Targets and Release Using Nuclease (CUT&RUN), an antibody-targeted chromatin profiling method developed by the Hutch’s Henikoff Lab to examine genome-wide occupancy of transcription factors and chromatin modifying proteins. CUT&RUN has been automated as AutoCUT&RUN, and we offer sample-to-Illumina library processing using a Beckman Biomek FX liquid-handling robot to facilitate high-throughput processing of 96 samples in two days.
Our experienced team will also work with you to develop and implement custom sequencing approaches.