Gut Puzzle Study

Join us for a short study we are calling Gut Puzzle!

The question we aim to answer is: Do our stool bacteria help predict how we metabolize different foods?

‘Metabolize’ refers to the vast network of reactions that change the food we eat into energy we can use, and into biomass (as in… the physical ‘stuff’ of our bodies, muscle, bone, etc.) In the gut, this metabolism is driven by the bacteria. We still do not fully understand how bacterial and human metabolism work together to determine how we respond to specific foods.

About the Study

This short research study takes only 4 days to complete. We give participants a food record booklet to keep track of everything eaten for 3 days. On the fourth day participants collect stool with a kit we provide, and come for a fasting blood draw at the Fred Hutch in South Lake Union.

You may be eligible if you are healthy, between 18-65 years old and:

  • don’t take diabetes medications
  • don’t take proton pump inhibitors (PPIs)
  • don’t have a history of gastrointestinal disorders (ulcerative colitis, Crohn disease, celiac sprue, etc.)
  • don’t drink more than 2 alcoholic drinks most days
  • have a BMI (Body Mass Index) between 18 and 35.  To see if you are eligible, see chart below

If you are interested in participating, please complete this initial questionnaire.

Study Activities

guts puzzle study timeline graphic

Body Mass Index Chart

To see if you are eligible based on BMI, find your height in the left-hand column labeled “Your Height”.  Move across to “Your Weight”.  If you weigh between the weights stated you may be eligible for this study.

Your Height Your Weight (lbs)
4'10" 86 and 167
4'11" 89 and 173
5'0" 92 and 179
5'1" 95 and 185
5'2" 98 and 191
5'3" 101 and 197
5'4" 104 and 203
5'5" 108 and 210
5'6" 112 and 217
5'7" 115 and 223
5"8" 118 and 230
5"9" 122 and 237
5'10" 126 and 244
5'11" 129 and 250
6'0" 133 and 258
6'1" 137 and 265
6'2" 140 and 272
6'3" 144 and 280
6'4" 148 and 287
This is a collaboration between the Institute of Systems Biology (ISB) and Fred Hutch, funded by NIH grant R01DK133468
Fred Hutchinson Cancer Center logo
C ISB logo

Study Contact

Contact us if you have any questions about the study.