Drug industry taking bigger role in cancer clinical trials
Dr. Joe Unger explained the scale of the cancer clinical trial funding gap: “We recognized that industry was playing an increasing role in cancer clinical research compared to decades ago. But we didn't realize the difference was this dramatic.”
Was Missouri’s bird flu case a one-off or something more? Quest for answers faces testing delay
Dr. Jesse Bloom explained how virus mutations could change the accuracy of serology tests for infections: "This type of mutation could make you want to then redo the assays with a virus that contained that mutation.”
Can AI cure cancer? New alliance unites tech giants and big research orgs in quest for breakthroughs
Dr. Thomas Lynch discussed the newly formed Cancer AI Alliance: “What was interesting about this whole process was how we were able to bring together these four incredible cancer centers, and these four major tech companies.”
The biology of ‘precancer’: stopping cancer before it starts
Dr. Ming Yu explained how aging cells that accumulate in the body can create a “tumor-promoting microenvironment,” but a certain drug may be able to eliminate these “zombie cells” and prevent them from developing into cancer.
A viral gene drive could offer a new approach to fighting herpes
Drs. Keith Jerome and Marius Walter discussed their Nature Communications study on gene editing for herpes. Jerome explained his hope for a herpes cure: “You don’t ever have to worry about this virus again.”
What does it mean to be immunocompromised?
Fred Hutch patient Kaley Karaffa and Dr. Josh Hill explained how being immunocompromised impacts daily life. Karaffa said, “I had to become cautious about who I saw, the activities I was involved in and even the kind of food I ate.”
Mammogram centers must now inform women about their breast density. Here’s how it could affect you
Dr. Brian Dontchos talked about dense breast classification: “Classification can vary depending on the doctor reading the mammogram because it’s somewhat subjective.” The story was syndicated in several news outlets.
The long shots: When patients defy all odds
Dr. Danielle Kirkey explained the balance of hope and reality when caring for patients. She said, "Anything we can do to give the best quality of life for as long as possible is always at the forefront of our mind.”
Meet the 2024 STAT Wunderkinds
STAT included Miguel Paredes in the Bedford Lab and Yapeng Su in the Greenberg Lab in its Wunkerkinds awards to 27 of the “most impressive doctors and researchers on the cusp of launching their careers.”
Advancing diversity, equity and inclusion through a challenging policy landscape
Dr. Chris Li and peers discussed DEI in the cancer workforce at a recent policy summit. In recruiting a diverse pool of job applicants, Li urged others to “treat search as a verb.”
What We Really Want From Life (But Might Not Know It) -- Medium, Oct. 23, 2024
Dr. Megan Shen summarized from her research of people facing serious illnesses that what people really want in life is “peace and love.” She added: “These are the only things that seemingly encompass all the other desires we have as humans.”
myeloMATCH to use genomics to enroll patients into target-based leukemia trials
Dr. Jerry Radich explained his lab’s involvement in a new NCI-led effort to use genomics testing to screen patients. He said, “What we learn from myeloMATCH may have a major impact on the future of clinical trials in leukemia and beyond.”
‘Stark’ finding: Cancer research in U.S. dominated by industry sponsors
Dr. Joe Unger pointed out that: “Federally sponsored, cancer clinical research has a unique role in identifying treatments that are best for patients. It’s not a role that can be supplanted by industry.”
Should First-Line Dual Checkpoint Blockade Be Used for NSCLC With Specific Mutations?
Dr. Lei Deng shared his thoughts on non-small cell lung cancer treatment data: “It is still not strong enough or definitive enough to make it standard of care to use dual checkpoint blockade for [patients with STK11 and/or KEAP1 mutations].”
COVID vaccine update: CDC now recommends second dose for older adults, immunocompromised
Dr. Larry Corey talked about the evolution of COVID noting, “The effects that the early vaccination had have long worn off, and the virus has escaped from them. The hope is double boosting will transfer your immunity.”
The truth about blood tests for cancer
Drs. Ruth Etzioni and Scott Ramsey discussed multi-cancer early detection blood tests. Etzioni noted, “The future of screening is going to look different from the past” although “we’re not quite there.”