Oncology Insights with Dr. Petros Grivas - Episode 19

Exploring advances in acute lymphoblastic leukemia with Dr. Ryan Cassaday

In this episode, host Petros Grivas, MD, PhD, FASCO, welcomes Ryan Cassaday, MD, a leukemia researcher and physician at Fred Hutch Cancer Center and a professor at the University of Washington School of Medicine, to discuss his path to oncology, recent advances in acute lymphoblastic leukemia (ALL) treatment and the importance of clinical trials and community partnerships. Listen to learn how emerging therapies and innovative research are helping improve outcomes and expand access to care for patients with ALL.

Key topics

  • Cassaday's career path and what inspired his interest in oncology and blood cancers

  • His research at Fred Hutch focused on novel immunotherapy- and chemotherapy-based approaches for ALL

  • The impact of bispecific T-cell engager therapies, including blinatumomab, and the potential of new formulations

  • Innovative clinical trial designs, including dose-adjusted EPOCH combined with monoclonal antibody therapies

  • The role of community partnerships in caring for patients with complex leukemia diagnoses

  • Opportunities and challenges in coordinating inpatient and outpatient leukemia care across large geographic regions

  • Fred Hutch's leadership in cellular therapies, stem cell transplantation and care for patients from around the world

  • Future directions in ALL treatment aimed at improving cure rates while reducing treatment-related burden

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