Oncology Insights with Dr. Petros Grivas - Episode 18

Dr. Annemarie Shepherd on proton therapy, clinical trials and the future of radiation oncology

In this episode, host Petros Grivas, MD, PhD, FASCO, welcomes Annemarie Shepherd, MD, the medical director of Fred Hutch Cancer Center – Proton Therapy, to discuss the field of proton therapy and its advancements. They explore the technology, clinical trials, patient-centered care, collaboration and the future of radiation oncology.

Key Topics:

  • Shepherd's journey from the Northeast to Fred Hutch and her move to Seattle

  • Overview of Fred Hutch Proton Therapy's technology and unique regional role

  • Advancements in proton therapy technology such as pencil beam and machine upgrades

  • Current and upcoming clinical trials: leptomeningeal disease treatment and hippocampal sparing in craniospinal radiation

  • National registry efforts through the Proton Collaborative Group

  • Collaboration with community healthcare providers for patient access

  • Future directions in radiation oncology: precision, integration with systemic therapies, and benign conditions

  • The interdisciplinary nature of thoracic oncology and team collaboration at Fred Hutch

  • Integration of artificial intelligence in radiation planning

  • Leadership insights: active listening and advocacy during organizational change

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