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Looking beyond suspect genes in cancer
Fred Hutch is among 10 institutions in the U.S., the U.K. and Europe collaborating to find the function of every protein-coding gene in the human genome
Conducting RNA reconnaissance
Fred Hutch researchers invent a CRISPR screening method to understand RNA-binding proteins often mutated in cancer and other diseases
Virologist and HIV expert Dr. Michael Emerman retires
Emerman considers mentorship his most important duty in science
Fred Hutch study finds genetic driver of drug resistance in small cell lung cancer
Researchers use CRISPR-Cas9 gene-editing tool on tumor cells grown in mice to better model how tumors that initially respond to chemotherapy become resistant
Rewriting the story about the molecules that turn genes on and off
Fred Hutch researchers discover that most transcription factors in budding yeast don’t follow the textbook example of binding close to the genes they regulate
Cell biologist and former Fred Hutch division leader Dr. Jonathan Cooper retires
Cooper sustained the distinct culture of Basic Sciences for four decades
Evolutionary cell biologist Dr. Grant King named a Hanna Gray Fellow
Long fascinated by life seen and unseen, King awarded eight years of funding to finish postdoctoral training at Fred Hutch and establish an independent lab
Cold air makes oxygen toxic for worms
Fred Hutch study shows C. elegans, a microscopic worm, can survive low temperatures if oxygen supply is also low
Tricking cells into trashing cancer
Fred Hutch chemical biologist rapidly reduces lung tumors in mice with a tagging system that grabs cancer-causing proteins and hauls them out with the molecular trash
Blocking a cancer escape hatch
Fred Hutch graduate student wins NIH F31 award to study structure of a key protein that helps blood vessels grow, but also helps cancer spread when it malfunctions
Cracking the sparkle code
Fred Hutch cancer biologist wins V Foundation Scholar Award to explore role of protein sugaring in leukemia tumors that survive chemotherapy
New deputy CMO brings Texas-sized expertise to Fred Hutch
Dr. Nicole Fleming takes over daily operations of South Lake Union clinic that has grown by 30% in three years
Finding a new way to break the supply chain fueling advanced prostate cancer
Fred Hutch researcher wins a $1M grant for a London-Seattle collaboration to find new therapies for drug-resistant prostate cancer
Bottleneck breakthrough
Fred Hutch researchers discover why some HIV-1 variants are more transmissible than others, which could generate new approaches to stop the virus that causes AIDS at cell entry
Making the most of a small supply
Fred Hutch researchers receive $1.3 million grant from the U.S. Department of Defense to study the fundamental biology of five rare liver cancers that could lead to new treatments one day
Almost as good as delivering flowers
Volunteer driver Bill Conquergood fights traffic so out-of-state patients don’t have to
Priming the pump for future funding
Fred Hutch postdoctoral researchers win NIH training fellowship for pancreatic cancer and kinetochore projects
Cell biologist Dr. Susan Parkhurst named 2024 ASCB fellow
Fred Hutch researcher honored by American Society for Cell Biology discusses integrating generations of scientists through mentorship
Making the leap from postdoc to principal investigator
Fred Hutch postdoctoral research fellow hopes to run her own lab with a transition award from the Cystic Fibrosis Foundation
Curiosity, connection and C. elegans
How a Fred Hutch worm study gives hope to families affected by an extremely rare genetic disorder