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List clinical trials by disease

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Searched for: Prostate Cancer. 23 results shown below.
Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Hormone-Resistant Prostate Cancer
Complete title: A Phase I/II Trial of Concurrent Chemohormonal therapy using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration Resistant Prostate Cancer

Principal Investigator: Heather Cheng

Study Number: 9279

Phase: I/II



Proton Therapy vs. IMRT for Low or Intermediate Risk Prostate Cancer (PARTIQoL)
Complete title: PARTIQol: Prostate Advance Radiation Technologies Investigating Quality of Life: A Phase III Randomized Clinical Trial of Proton Therapy vs. IMRT for Low or Intermediate Risk Prostate Cancer

Principal Investigator: Jing Zeng

Study Number: 9328

Phase: III



Diet and Exercise Program in Promoting Weight Loss and Improving Health in Patients With Low- or Low-Intermediate-Risk Prostate Cancer (PALS)
Complete title: PALS: Prostate Cancer Active Lifestyle Study

Principal Investigator: Jonathan Wright

Study Number: 9369

Phase: N/A



Docetaxel and Carboplatin in Treating Patients With Metastatic, Castration Resistant Prostate Cancer Containing Inactivated Genes in the BRCA 1/2 Pathway
Complete title: A Pilot Study of Docetaxel and Carboplatin for Treatment of Patients with Metastatic, Castration Resistant Prostate Cancer Containing Biallelic Inactivation of Genes in the BRCA1/2 Pathway

Principal Investigator: Heather Cheng

Study Number: 9381

Phase: II



Sirolimus, Docetaxel, and Carboplatin in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
Complete title: A Phase 1-2 Study of Sirolimus, Docetaxel and Carboplatin for Treatment of Patients with Metastatic, Castration Resistant Prostate Cancer: (Rapamycin inhibition of DDSP [RID])

Principal Investigator: Robert Montgomery, MD

Study Number: 9388

Phase: I/II



Apalutamide in Treating Patients With Prostate Cancer Who Are in Active Surveillance
Complete title: A Phase 2 Study of Apalutamide in Active Surveillance Patients

Principal Investigator: Michael Schweizer

Study Number: 9582

Phase: II



INTense Exercise foR surVivAL Among Men With Metastatic Castrate-Resistant Prostate Cancer (INTERVAL)
Complete title: The GAP4 Study: INTense Exercise foR surVivAL among Men with Metastatic Castrate-Resistant Prostate Cancer (INTERVAL - MCRPC): A Multicenter, Randomized, Controlled Phase III Study

Principal Investigator: Jonathan Wright

Study Number: 9665

Phase: III



Use of an Experimental Drug, CC-115, With Enzalutamide in Men With Castration-Resistant Prostate Cancer
Complete title: A Phase 1b Study of Enzalutamide plus CC-115 in Men with Castration-Resistant Prostate Cancer (CRPC)

Principal Investigator: Heather Cheng

Study Number: 9767

Phase: I



Genetic Testing for Men With Metastatic Prostate Cancer (GENTleMEN)
Complete title: GENTleMEN: GENetic Testing for MEN with metastatic prostate cancer

Principal Investigator: Heather Cheng

Study Number: 9831

Phase: N/A



Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency
Complete title: PLATI-PARP: A Phase 2 Study of Induction Docetaxel and Carboplatin followed by Maintenance Rucaparib in Treatment of Patients with Metastatic Castration Resistant Prostate Cancer with Homologous Recombination DNA Repair Deficiency

Principal Investigator: Heather Cheng

Study Number: 9841

Phase: II



Testosterone Enanthate and Olaparib in Treating Participants With Castration-Resistant Prostate Cancer
Complete title: Bipolar Androgen Therapy Plus Olaparib in Patient with Castration-Resistant Prostate Cancer

Principal Investigator: Michael Schweizer

Study Number: 9984

Phase: II



Olaparib Before Surgery in Treating Participants With Localized Prostate Cancer
Complete title: Open-Label, Pilot Study of Olaparib as a Neoadjuvant Therapy for Patients Undergoing Prostatectomy for Localized Prostate Cancer

Principal Investigator: Robert Montgomery, MD

Study Number: 9985

Phase: II



Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer
Complete title: Molecular Correlates of Sensitivity and Resistance to Therapy in Genitourinary Malignancy

Principal Investigator: Robert Montgomery, MD

Study Number: 6932

Phase: N/A



Phase 1/1b Study of MGCD516 in Patients With Advanced Cancer
Complete title: A Phase 1/1b Study of MGCD516 in Patients With Advanced Solid Tumor Malignancies

Principal Investigator: Keith Eaton, MD, PhD

Study Number: 20150094

Phase: I



A Phase 1 Study To Evaluate Escalating Doses Of A Vaccine-Based Immunotherapy Regimen For Prostate Cancer (PrCa VBIR)
Complete title: A Phase I Study to Evaluate The Safety, PHarmacokinetics and PHarmacodynamics of Escalating Doses of a Vaccine-Based Immunotherapy Regimen (VBIR) for Prostate Cancer (PF-06753512)

Principal Investigator: Tia Higano, MD

Study Number: 20151318

Phase: I



Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK1/2/3, ROS1, or ALK Gene Rearrangements (Fusions) (STARTRK-2)
Complete title: An Open-Label, Multicenter, Global Phase II Basket Study of Entrectinib for the Treatment of Patients with Locally Advanced or Metastatic Solid Tumors that Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements

Principal Investigator: Gabriela Chiorean

Study Number: 20152369

Phase: II



A Phase 1 Trial of a Novel XPO1 Inhibitor in Patients With Advanced Solid Tumors
Complete title: A Phase 1 Study of SL-801, a Reversible Inhibitor of Nuclear Export, in Patients with Advanced Solid Tumors

Principal Investigator: Gabriela Chiorean

Study Number: 20160524

Phase: I



An Efficacy and Safety Study of Niraparib in Men With Metastatic Castration-Resistant Prostate Cancer and DNA-Repair Anomalies (Galahad)
Complete title: A Phase 2 Efficacy and Safety Study of Niraparib in Men with Metastatic Castration-Resistant Prostate Cancer and DNA-Repair Anomalies

Principal Investigator: Heather Cheng

Study Number: 20162044

Phase: II



A Study of ZEN003694 in Combination With Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer
Complete title: A Phase 1 Safety and Tolerability Study of ZEN003694 in Combination with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer

Principal Investigator: Michael Schweizer

Study Number: 20162882

Phase: I



Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
Complete title: Phase Ib/II Trial of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (mCRPC) (KEYNOTE-365)

Principal Investigator: Evan Yu, MD

Study Number: 20162991

Phase: I/II



A Phase I/Ib Study of NIZ985 in Combination With PDR001 in Adults With Metastatic Cancers
Complete title: A Phase 1/1b Study of Subcutaneous Recombinant Human NIZ985 ((hetIL-15) (IL15/sIL-15-15Ra)) alone and in Combination with PDR001 in Adults with Metastatic Cancers

Principal Investigator: John Thompson, MD

Study Number: 20170681

Phase: I



A Trial Comparing Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Advanced Prostate Cancer and Cardiovascular Disease (PRONOUNCE)
Complete title: A Multi-Center, Randomized, Assessor-Blind, Controlled Trial Comparing the Occurrence of Major Adverse Cardiovascular Events (MACEs) in Patients with Prostate Cancer and Cardiovascular Disease Receiving Degarelix (GnRH Receptor Antagonist) or Leuprolide (GnRH Receptor Agonist)

Principal Investigator: Tia Higano, MD

Study Number: 20182038

Phase: III



Phase 1/2 Study of LOXO-195 in Patients With Previously Treated NTRK Fusion Cancers
Complete title: A Phase 1/2 Study of the TRK Inhibitor LOXO-195 in Adult and Pedicatric Subjects with Previously treated NTRK Fusion Cancers

Principal Investigator: Catherine Albert, MD

Study Number: SC-4016

Phase: I



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