Study of Novel Treatment Combinations in Patients With Lung Cancer (VELOCITY-Lung)

The goal of this platform clinical trial is to test how well novel treatment combinations work in participants with lung cancer. Substudy-01 will compare the different novel combinations versus standard of care in participants with metastatic (cancer that has spread) non-small-cell lung cancer (NSCLC) who have have not been treated before. Substudy-02 will compare the different novel combination versus standard of care in participants with cancer that has progressed after receiving previous treatment for metastatic NSCLC. New substudies and/or treatment arms may be added to the study through amendment of the master protocol and/or substudy protocols.