Study of Magrolimab Given Together With FOLFIRI/BEV in Participants With Previously Treated Advanced Inoperable Metastatic Colorectal Cancer (mCRC) (Elevate mCRC)

Complete Title: Preliminary Studies Using Archived Tissue Brain Tumor
Trial Phase: II
Investigator: Eric Holland, MD, PhD

The primary objectives of this study are: (safety run-in cohort) to evaluate safety and tolerability, and the recommended Phase 2 dose (RP2D) and (randomized cohort) to evaluate the efficacy of magrolimab in combination with bevacizumab and 5-fluorouracil, irinotecan, and leucovorin (FOLFIRI) in previously treated participants with advanced inoperable metastatic colorectal cancer (mCRC).

Keywords:
  • Colorectal Neoplasms
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Adult
II
Eric Holland, MD, PhD
RG1121925
NCT05330429
Preliminary Studies Using Archived Tissue Brain Tumor
Colorectal Neoplasms