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Clinical Trial Details
Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations (SURF301)
Complete Title: A Multicenter, Open-label Phase 1/2 Study of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors with Activating FGFR3 Gene Alterations (SURF-301)
Trial Phase: I/II
Investigator: Evan Yu
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of TYRA-300 in cancers with FGFR3 activating gene alterations, including locally advanced/metastatic urothelial carcinoma of the bladder and urinary tract and other advanced solid tumors.
Keywords:
- Bladder Cancer
- Solid Tumors
- Urothelial Cancer
- Urinary Bladder Neoplasms
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Adult
I/II
Evan Yu
RG1122949
NCT05544552
A Multicenter, Open-label Phase 1/2 Study of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors with Activating FGFR3 Gene Alterations (SURF-301)
Bladder Cancer
Solid Tumors
Urothelial Cancer
Urinary Bladder Neoplasms