Pembrolizumab and Carboplatin for the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Complete Title: A Phase II Study of Anti-PD-1 (pembrolizumab) in Combination with Carboplatin to Prevent Progression after Serologic Detection of Recurrent Ovarian Cancer
Trial Phase: II
Investigator: John Liao

This phase II trial investigates how well pembrolizumab and carboplatin work in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has come back (recurrent). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body`s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pembrolizumab together with carboplatin may work better in treating patients with recurrent ovarian, fallopian tube, or primary peritoneal cancer.

Keywords:
  • Fallopian Cancer
  • Ovarian Cancer
  • Peritoneal Cancer, Primary (PPC)
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Adult
II
John Liao
RG1007137
NCT04387227
A Phase II Study of Anti-PD-1 (pembrolizumab) in Combination with Carboplatin to Prevent Progression after Serologic Detection of Recurrent Ovarian Cancer
Fallopian Cancer
Ovarian Cancer
Peritoneal Cancer, Primary (PPC)