Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

Complete Title: A randomized phase 3 trial of fludarabine/cytarabine/gemtuzumab ozogamicin with or without venetoclax in children with relapsed AML
Trial Phase: III
Investigator: Katherine Tarlock

A study to evaluate if the randomized addition of venetoclax to a chemotherapy backbone (fludarabine/cytarabine/gemtuzumab ozogamicin [GO]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse who are unable to receive additional anthracyclines, or in 2nd relapse.

Keywords:
  • Leukemia, Acute Myeloid (AML)
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Adult
Pediatric
III
Katherine Tarlock
RG1123014
NCT05183035
A randomized phase 3 trial of fludarabine/cytarabine/gemtuzumab ozogamicin with or without venetoclax in children with relapsed AML
Leukemia, Acute Myeloid (AML)