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New Science Spotlight Articles
Every month, Fred Hutch postdoc writer/editors summarize two papers from each of our scientific divisions to stimulate collaborations across campus
13 NEW
May 24, 2023
Localized delivery of CAR T cells to treat children with brain tumors
From the Paulovich Lab, Translational Science and Therapeutics Division and Nicholas Vitanza Seattle Children’s Research Institute
Science Spotlight - April 17, 2023
Tags
Clinical Research
Translational Science and Therapeutics
seattle children's
Amanda Paulovich
Julie R. Park
Michael Jensen
CAR t-cell
pediatric brain tumors
Brain Tumors
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Methods for the masses: multiplexed growth signaling analyses by mass spec
From the Paulovich Lab, Clinical Research Division, and colleagues
Science Spotlight - June 21, 2021
Tags
Clinical Research Division (CRD)
Paulovich Lab
Amanda Paulovich
mass spectrometry
assay development
proteomic assays
cellular proliferation
cell growth
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Omics made easier
To see the big picture, just add ‘ome’
Hutch News - March 30, 2021
Tags
genomics
metagenomics
genome
epigenetics
metabolites
metabolomics
metabolism
alternative rna splicing
proteomics
microbiome
Steven Henikoff
Neelendu Dey
Lucas Sullivan
Amanda Paulovich
Robert Bradley
Human Biology
Clinical Research
Basic Sciences
Public Health Sciences
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One more hat: new roles for TGFβ in the DNA damage response
From the Paulovich Lab, Clinical Research Division, and colleagues
Science Spotlight - March 15, 2021
Tags
Clinical Research
Paulovich Lab
Amanda Paulovich
mass spectrometry
TGFb protein
dna repair
Cancers
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Scientists predict progress against COVID-19, cancer in 2021
After a challenging and deadly 2020, some hopeful predictions for the new year
Hutch News - December 22, 2020
Tags
Keith Jerome
Public Health Sciences
Lawrence Corey
Brain Tumors
HIV AIDS
cell and gene therapy
Clinical Research
Julie McElrath
Vaccine development - Viral cancers
Vaccine and Infectious Disease
precision medicine
herpes
Andrew Cowan
Amanda Paulovich
health disparities
Parth Shah
Herpesvirus Infections
vaccine development
Multiple Myeloma
COVID-19
virology
diagnostics and biomarkers
Tumor specific translational research
CAR t-cell
Transplant and Immunotherapy
CoVPN
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A path opens for precise analyses of breast cancer proteins
Paulovich lab runs CLIA-cleared tests to find patients appropriate for new HER2-targeted therapies
Hutch News - July 27, 2020
Tags
diagnostics and biomarkers
gene regulation and expression
immunotherapy
Breast Cancer
cancer proteomics
Amanda Paulovich
Paulovich Lab
mass spectrometry
precision diagnostics
precision medicine
tumor biomarker
Sabin Russell
Cecilia Yeung
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Targeting metastatic breast cancer with CAR T-cell immunotherapy
$4M 'Breakthrough' award funds collaborative research aimed at destroying dormant disseminated tumor cells
Hutch News - November 04, 2019
Tags
immunotherapy
metastatic breast cancer
CAR t-cell
Transplant and Immunotherapy
Cyrus Ghajar
Stanley R Riddell
Clinical Research
Public Health Sciences
Amanda Paulovich
Mark B. Headley
Ted A Gooley
Breast Cancer
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Stronger and faster is not always better
From the Riddell, Paulovich Labs, Clinical Research Division and Gottardo Lab, Vaccine and Infectious Disease Division.
Science Spotlight - October 15, 2018
Tags
CAR t-cell
Stanley R Riddell
Riddell Lab
Amanda Paulovich
Raphael Gottardo
Gottardo Lab
Science Signaling
Cancers
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Squelching ovarian cancer: the not-so-silent killer
The search continues for new biomarkers, better outcomes and, yes, cures for this deadly disease
Hutch News - September 17, 2018
Tags
Ovarian Cancer
gynecologic oncology
Amanda Paulovich
Charles Drescher
Jason Bielas
M. Robyn Andersen
Nicole Urban
Canary Foundation
t cell therapy
immunotherapy
genomics
proteomics
Angelina Jolie
Public Health Sciences Division (PHS)
biomarker
Cancer etiology - prevention - outcomes
Molecular basis of cancer
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First in-depth profile of CAR T-cell signals suggests how to improve immunotherapy
A Science Signaling paper reports how two common CAR designs impact T-cell efficacy against cancer in the laboratory
News Releases - August 21, 2018
Tags
Stanley R Riddell
Immunotherapy IRC (IIRC)
Amanda Paulovich
CAR t-cell
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Want to make better T-cell therapies? First, figure out how they work.
New study maps out activities, effects of widely used components in cellular immunotherapies
Hutch News - August 21, 2018
Tags
Clinical Research
Stanley R Riddell
Amanda Paulovich
Raphael Gottardo
immunotherapy
Transplant and Immunotherapy
chimeric antigen receptor
t cell therapy
signal pathways
Cancers
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Good News: Fred Hutch scientists to develop bioassay for ovarian cancer for new NCI initiative
Celebrating faculty and staff achievements
Hutch News - June 29, 2017
Tags
Amanda Paulovich
Clinical Research
proteomics
Ovarian Cancer
Tumor specific translational research
Sunil Hingorani
Pancreatic Cancer
Michael Boeckh
Vaccine and Infectious Disease
Vaccine Development
infectious disease
Seattle Cancer Care Alliance (SCCA)
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Proteowhatnow? 6 questions with a proteomics expert
How a new technology could help identify the best cancer treatment for an individual patient
Hutch News - April 05, 2017
Tags
Cancers
Clinical Research
Amanda Paulovich
Molecular basis of cancer
proteomics
personalized medicine
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Good News: Communications & Marketing wins 12 creativity awards
Celebrating faculty and staff achievements
Hutch News - February 09, 2017
Tags
Marketing & Communications
Administration
Amanda Paulovich
Paulovich Lab
Clinical Research
proteomics
cancer moonshot
Molecular basis of cancer
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Good News: Ceballos honored for public health research; ACS research awards to three Hutch scientists; ASH grant to physician-researcher; Paulovich facilitates Moonshot panel
Celebrating faculty and staff achievements
Hutch News - November 21, 2016
Tags
Public Health Sciences
survivorship
national cancer institutes
T cell
Cierra Sisters
american cancer society
Clinical Research
hutchinson institute for cancer outcomes research
proteomics
Star Study
Cancer etiology - prevention - outcomes
Vice President Joe Biden
Biggins Lab
cancer moonshot
Amanda Paulovich
acute myeloid leukemia
hicor
immunotherapy
cell division
Matthias Stephan
Sue Biggins
american society of hematology
Gary Lyman
Tumor specific translational research
Bridgette Hempstead
Basic Sciences
chromosome
Stanley R Riddell
Molecular basis of cancer
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Good News: Dr. Jeff Whiteaker wins NCI Research Specialist Award; Human Biology gains four new faculty members
Celebrating faculty and staff achievements
Hutch News - September 30, 2016
Tags
Amanda Paulovich
Paulovich Lab
proteomics
proteomic assays
Clinical Research
Human Biology
cptac
moonshot initiative
protein
oncology
Lung Cancer
Liver Cancer
Cancers
Pancreatic Cancer
gene mutation
cancer therapies
Alice Berger
Molecular basis of cancer
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Hyundai Hope on Wheels presents $250K grant for pediatric cancer research; Drs. Amanda Paulovich, Jeff Whiteaker facilitate 'first step' in expanding NCI’s Protein Assay Portal
Celebrating faculty and staff achievements
Hutch News - September 16, 2016
Tags
proteomics
cancer proteomics
protein
proteomic assays
nci
national cancer institutes
cancer moonshot
Amanda Paulovich
Vice President Joe Biden
cptac
genome
mass spectrometry
Cancers
Clinical Research
dna
Hyundai Hope on Wheels
Roland Walter
immune cells
neuroblastoma
T cell
funding sources
Pediatric Oncology
Transplant and Immunotherapy
Share
‘We can get this done’: National Cancer Moonshot takes flight
Moonshot Summit at Fred Hutch part of coast-to-coast conversation to stop cancer
Hutch News - June 29, 2016
Tags
Vice President Joe Biden
cancer moonshot
D. Gary Gilliland
Amanda Paulovich
Paulovich Lab
big data
Matthew Trunnell
Frederick Appelbaum
genomics
cancer moonshot summit
Transplant and Immunotherapy
Share
Filling in the ‘missing biology’ of breast cancer
Study demonstrates important role of proteomics in personalized medicine
Hutch News - May 25, 2016
Tags
Amanda Paulovich
Paulovich Lab
Breast Cancer
Human Biology
dna
human genome project
Share
Drs. Michael Emerman and Nina Salama elected to Fellowship in the American Academy of Microbiology
Celebrating faculty and staff achievements
Hutch News - March 10, 2016
Tags
Michael Emerman
Nina Salama
Human Biology
Basic Sciences
Public Health Sciences
microbiology
h pylori
genomics
hiv
paleovirology
Esophageal Cancer
Seattle Barrett's Esophagus Research
esophageal adenocarcinoma
Georg Luebeck
Computational Biology
Andrew Hsieh
molecular biology
Oliver Press
Lawrence Corey
David M Hockenbery
Hans-Peter Kiem
Stephanie Lee
Paul Nghiem
Amanda Paulovich
Scott Ramsey
Breast Cancer Initiative 2.5 (BCI2.5)
globam
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Fred Hutchinson Cancer Center
Hutch News
Last Modified, April 02, 2020